Published in J Biol Chem on April 21, 2004
The spectrin-ankyrin-4.1-adducin membrane skeleton: adapting eukaryotic cells to the demands of animal life. Protoplasma (2010) 1.26
NuMA localization, stability, and function in spindle orientation involve 4.1 and Cdk1 interactions. Mol Biol Cell (2013) 0.96
Downregulation of protein 4.1R, a mature centriole protein, disrupts centrosomes, alters cell cycle progression, and perturbs mitotic spindles and anaphase. Mol Cell Biol (2008) 0.91
Mitotic regulation of protein 4.1R involves phosphorylation by cdc2 kinase. Mol Biol Cell (2004) 0.87
Structural protein 4.1R is integrally involved in nuclear envelope protein localization, centrosome-nucleus association and transcriptional signaling. J Cell Sci (2011) 0.79
Alternatively spliced exon 5 of the FERM domain of protein 4.1R encodes a novel binding site for erythrocyte p55 and is critical for membrane targeting in epithelial cells. Biochim Biophys Acta (2008) 0.77
Protein 4.1R self-association: identification of the binding domain. Biochem J (2006) 0.75
Comprehensive characterization of protein 4.1 expression in epithelium of large intestine. Histochem Cell Biol (2014) 0.75
Phase I clinical trial of a selective inhibitor of CYP17, abiraterone acetate, confirms that castration-resistant prostate cancer commonly remains hormone driven. J Clin Oncol (2008) 10.91
Selective inhibition of CYP17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer. J Clin Oncol (2009) 6.68
Phase I clinical trial of the CYP17 inhibitor abiraterone acetate demonstrating clinical activity in patients with castration-resistant prostate cancer who received prior ketoconazole therapy. J Clin Oncol (2010) 6.04
Significant and sustained antitumor activity in post-docetaxel, castration-resistant prostate cancer with the CYP17 inhibitor abiraterone acetate. J Clin Oncol (2010) 5.86
Visualization of a Ran-GTP gradient in interphase and mitotic Xenopus egg extracts. Science (2002) 4.26
A Rae1-containing ribonucleoprotein complex is required for mitotic spindle assembly. Cell (2005) 3.65
Dissection of the mammalian midbody proteome reveals conserved cytokinesis mechanisms. Science (2004) 3.48
Analysis of a RanGTP-regulated gradient in mitotic somatic cells. Nature (2006) 3.47
Mechanisms of mitotic spindle assembly and function. Int Rev Cytol (2008) 3.44
Mechanisms and molecules of the mitotic spindle. Curr Biol (2004) 3.25
Resolving the distinct stages in erythroid differentiation based on dynamic changes in membrane protein expression during erythropoiesis. Proc Natl Acad Sci U S A (2009) 3.00
Allele-specific silencing of dominant disease genes. Proc Natl Acad Sci U S A (2003) 3.00
Erythroblastic islands: niches for erythropoiesis. Blood (2008) 2.93
The RanGTP gradient - a GPS for the mitotic spindle. J Cell Sci (2008) 2.78
Primary role for adherent leukocytes in sickle cell vascular occlusion: a new paradigm. Proc Natl Acad Sci U S A (2002) 2.72
Hereditary spherocytosis. Lancet (2008) 2.37
Direct determination of lipoprotein particle sizes and concentrations by ion mobility analysis. Clin Chem (2008) 2.27
A band 3-based macrocomplex of integral and peripheral proteins in the RBC membrane. Blood (2003) 2.24
Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice. J Clin Invest (2010) 2.18
Protein 4.1R-dependent multiprotein complex: new insights into the structural organization of the red blood cell membrane. Proc Natl Acad Sci U S A (2008) 2.18
Katanin contributes to interspecies spindle length scaling in Xenopus. Cell (2011) 2.16
Hypoxia-induced acute lung injury in murine models of sickle cell disease. Am J Physiol Lung Cell Mol Physiol (2003) 2.08
Contribution of parasite proteins to altered mechanical properties of malaria-infected red blood cells. Blood (2002) 1.93
The dendritic cell receptor Clec9A binds damaged cells via exposed actin filaments. Immunity (2012) 1.89
A transgenic mouse model demonstrates a dominant negative effect of a point mutation in the RPS19 gene associated with Diamond-Blackfan anemia. Blood (2010) 1.88
Cytoplasmic volume modulates spindle size during embryogenesis. Science (2013) 1.88
Quantitative assessment of sensing and sequestration of spherocytic erythrocytes by the human spleen. Blood (2012) 1.87
Hereditary spherocytosis and hereditary elliptocytosis: aberrant protein sorting during erythroblast enucleation. Blood (2010) 1.81
Investigating mitotic spindle assembly and function in vitro using Xenopus laevis egg extracts. Nat Protoc (2006) 1.80
Nuclear size is regulated by importin α and Ntf2 in Xenopus. Cell (2010) 1.79
Disorders of red cell membrane. Br J Haematol (2008) 1.74
A Maurer's cleft-associated protein is essential for expression of the major malaria virulence antigen on the surface of infected red blood cells. J Cell Biol (2006) 1.73
The spectrin-based membrane skeleton stabilizes mouse megakaryocyte membrane systems and is essential for proplatelet and platelet formation. Blood (2011) 1.67
Methods for studying spindle assembly and chromosome condensation in Xenopus egg extracts. Methods Mol Biol (2006) 1.65
Identification of a novel protein regulating microtubule stability through a chemical approach. Chem Biol (2004) 1.64
Xenopus tropicalis egg extracts provide insight into scaling of the mitotic spindle. J Cell Biol (2007) 1.63
Targeted gene deletion demonstrates that the cell adhesion molecule ICAM-4 is critical for erythroblastic island formation. Blood (2006) 1.63
REEP3/4 ensure endoplasmic reticulum clearance from metaphase chromatin and proper nuclear envelope architecture. Dev Cell (2013) 1.62
Cytoskeletal protein 4.1R negatively regulates T-cell activation by inhibiting the phosphorylation of LAT. Blood (2009) 1.57
Genome-wide analysis demonstrates conserved localization of messenger RNAs to mitotic microtubules. J Cell Biol (2007) 1.55
Malaria and the red blood cell membrane. Semin Hematol (2004) 1.54
Identification of a functional role for lipid asymmetry in biological membranes: Phosphatidylserine-skeletal protein interactions modulate membrane stability. Proc Natl Acad Sci U S A (2002) 1.53
Modulation of erythrocyte membrane mechanical function by protein 4.1 phosphorylation. J Biol Chem (2004) 1.53
A computational model predicts Xenopus meiotic spindle organization. J Cell Biol (2010) 1.53
Mechanism of protein sorting during erythroblast enucleation: role of cytoskeletal connectivity. Blood (2003) 1.52
The sensing of poorly deformable red blood cells by the human spleen can be mimicked in vitro. Blood (2010) 1.52
Membrane remodeling during reticulocyte maturation. Blood (2009) 1.47
Shear-response of the spectrin dimer-tetramer equilibrium in the red blood cell membrane. J Biol Chem (2002) 1.46
Disease-related modifications in tau affect the interaction between Fyn and Tau. J Biol Chem (2005) 1.45
Nonhuman primate model of pertussis. Infect Immun (2012) 1.45
Malaria, erythrocytic infection, and anemia. Hematology Am Soc Hematol Educ Program (2009) 1.44
Histone H1 is essential for mitotic chromosome architecture and segregation in Xenopus laevis egg extracts. J Cell Biol (2005) 1.43
The ring-infected erythrocyte surface antigen (RESA) of Plasmodium falciparum stabilizes spectrin tetramers and suppresses further invasion. Blood (2007) 1.42
Red blood cell blood group antigens: structure and function. Semin Hematol (2004) 1.42
Adducin forms a bridge between the erythrocyte membrane and its cytoskeleton and regulates membrane cohesion. Blood (2009) 1.42
Rac GTPases regulate the morphology and deformability of the erythrocyte cytoskeleton. Blood (2006) 1.41
Structural and functional studies of interaction between Plasmodium falciparum knob-associated histidine-rich protein (KAHRP) and erythrocyte spectrin. J Biol Chem (2005) 1.41
Importazole, a small molecule inhibitor of the transport receptor importin-β. ACS Chem Biol (2011) 1.39
Interneuronal transfer of human tau between Lamprey central neurons in situ. J Alzheimers Dis (2010) 1.39
Quantitative analysis of murine terminal erythroid differentiation in vivo: novel method to study normal and disordered erythropoiesis. Blood (2013) 1.39
Fluctuations of the red blood cell membrane: relation to mechanical properties and lack of ATP dependence. Biophys J (2008) 1.38
Erythrocyte remodeling by malaria parasites. Curr Opin Hematol (2007) 1.37
Mechanisms of intracellular scaling. Annu Rev Cell Dev Biol (2012) 1.35
Lineage and species-specific long noncoding RNAs during erythro-megakaryocytic development. Blood (2014) 1.34
Racial differences in human platelet PAR4 reactivity reflect expression of PCTP and miR-376c. Nat Med (2013) 1.34
Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice. Blood (2008) 1.32
The hydration state of human red blood cells and their susceptibility to invasion by Plasmodium falciparum. Blood (2005) 1.32
Erythrocyte G protein as a novel target for malarial chemotherapy. PLoS Med (2006) 1.31
Erythrocyte G protein-coupled receptor signaling in malarial infection. Science (2003) 1.31
Xorbit/CLASP links dynamic microtubules to chromosomes in the Xenopus meiotic spindle. J Cell Biol (2006) 1.31
Conformational stabilities of the structural repeats of erythroid spectrin and their functional implications. J Biol Chem (2006) 1.29
Micromanipulation studies of chromatin fibers in Xenopus egg extracts reveal ATP-dependent chromatin assembly dynamics. Mol Biol Cell (2006) 1.27
Erythrocyte detergent-resistant membrane proteins: their characterization and selective uptake during malarial infection. Blood (2003) 1.26
Hereditary spherocytosis, elliptocytosis, and other red cell membrane disorders. Blood Rev (2013) 1.26
Characterization of glycolytic enzyme interactions with murine erythrocyte membranes in wild-type and membrane protein knockout mice. Blood (2008) 1.23
Ribosomal protein S19 expression during erythroid differentiation. Blood (2002) 1.20
Mitotic spindle scaling during Xenopus development by kif2a and importin α. Elife (2013) 1.18
Cytoskeletal protein 4.1R affects repolarization and regulates calcium handling in the heart. Circ Res (2008) 1.17
Nuclear actin and protein 4.1: essential interactions during nuclear assembly in vitro. Proc Natl Acad Sci U S A (2003) 1.17
Complement depletion renders C57BL/6 mice sensitive to the Bacillus anthracis Sterne strain. Infect Immun (2005) 1.17
Study of the effects of proteasome inhibitors on ribosomal protein S19 (RPS19) mutants, identified in patients with Diamond-Blackfan anemia. Haematologica (2008) 1.16
The perichromosomal layer. Chromosoma (2005) 1.16
Chromatin condensation in terminally differentiating mouse erythroblasts does not involve special architectural proteins but depends on histone deacetylation. Chromosome Res (2009) 1.16
Significant biochemical, biophysical and metabolic diversity in circulating human cord blood reticulocytes. PLoS One (2013) 1.15
The contribution of endothelial cell P-selectin to the microvascular flow of mouse sickle erythrocytes in vivo. Blood (2004) 1.15
Functional characterization of spectrin-actin-binding domains in 4.1 family of proteins. Biochemistry (2002) 1.15
Nuclear substructure reorganization during late-stage erythropoiesis is selective and does not involve caspase cleavage of major nuclear substructural proteins. Blood (2005) 1.15
Identification and functional characterization of protein 4.1R and actin-binding sites in erythrocyte beta spectrin: regulation of the interactions by phosphatidylinositol-4,5-bisphosphate. Biochemistry (2005) 1.13
A dynamic alternative splicing program regulates gene expression during terminal erythropoiesis. Nucleic Acids Res (2014) 1.13
Plasmodium falciparum erythrocyte membrane protein 3 (PfEMP3) destabilizes erythrocyte membrane skeleton. J Biol Chem (2007) 1.12