Published in Biochemistry on May 25, 2004
Glucose signaling in Saccharomyces cerevisiae. Microbiol Mol Biol Rev (2006) 3.16
Regulation of G0 entry by the Pho80-Pho85 cyclin-CDK complex. EMBO J (2005) 1.51
Goa1p of Candida albicans localizes to the mitochondria during stress and is required for mitochondrial function and virulence. Eukaryot Cell (2009) 1.07
Pichia pastoris 14-3-3 regulates transcriptional activity of the methanol inducible transcription factor Mxr1 by direct interaction. Mol Microbiol (2012) 0.98
Deleting the 14-3-3 protein Bmh1 extends life span in Saccharomyces cerevisiae by increasing stress response. Genetics (2009) 0.90
Bmh1p (14-3-3) mediates pathways associated with virulence in Candida albicans. Microbiology (2009) 0.86
14-3-3 (Bmh) proteins inhibit transcription activation by Adr1 through direct binding to its regulatory domain. Mol Cell Biol (2010) 0.85
The yeast 14-3-3 proteins BMH1 and BMH2 differentially regulate rapamycin-mediated transcription. Biosci Rep (2014) 0.82
The proteome response to amyloid protein expression in vivo. PLoS One (2012) 0.80
Binding and transcriptional regulation by 14-3-3 (Bmh) proteins requires residues outside of the canonical motif. Eukaryot Cell (2013) 0.79
The Hsp70 homolog Ssb and the 14-3-3 protein Bmh1 jointly regulate transcription of glucose repressed genes in Saccharomyces cerevisiae. Nucleic Acids Res (2016) 0.77
The yeast Hsp70 homolog Ssb: a chaperone for general de novo protein folding and a nanny for specific intrinsically disordered protein domains. Curr Genet (2016) 0.75
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature (2006) 24.39
The role of autophagy during the early neonatal starvation period. Nature (2004) 22.40
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell (2005) 21.01
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy (2007) 20.92
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice. J Cell Biol (2005) 18.60
In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. Mol Biol Cell (2003) 17.55
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene. J Clin Invest (2003) 16.67
Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice. Cell (2007) 14.63
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat Chem Biol (2005) 11.63
Autophagy in immunity and inflammation. Nature (2011) 11.16
A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells. Nature (2008) 10.84
Autophagy defends cells against invading group A Streptococcus. Science (2004) 9.53
Dynamics and diversity in autophagy mechanisms: lessons from yeast. Nat Rev Mol Cell Biol (2009) 9.32
LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation. J Cell Sci (2004) 9.20
A unified nomenclature for yeast autophagy-related genes. Dev Cell (2003) 9.18
Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy. Mol Biol Cell (2009) 9.14
Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes. Nat Cell Biol (2004) 8.85
The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress. Nat Med (2007) 8.82
The role of Atg proteins in autophagosome formation. Annu Rev Cell Dev Biol (2011) 8.18
Autophagy-dependent viral recognition by plasmacytoid dendritic cells. Science (2007) 7.65
Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages. Nat Cell Biol (2009) 7.35
Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG. Mol Biol Cell (2008) 7.32
FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells. J Cell Biol (2008) 7.16
Atg8, a ubiquitin-like protein required for autophagosome formation, mediates membrane tethering and hemifusion. Cell (2007) 7.11
Escape of intracellular Shigella from autophagy. Science (2004) 6.64
Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate. J Cell Sci (2003) 6.50
The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy. J Biol Chem (2007) 6.28
Hierarchy of Atg proteins in pre-autophagosomal structure organization. Genes Cells (2007) 6.14
A critical role for the autophagy gene Atg5 in T cell survival and proliferation. J Exp Med (2006) 6.01
Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy. Dev Cell (2009) 5.85
Autophagosome formation in mammalian cells. Cell Struct Funct (2002) 5.58
A large-scale full-length cDNA analysis to explore the budding yeast transcriptome. Proc Natl Acad Sci U S A (2006) 5.24
De novo mutations in the autophagy gene WDR45 cause static encephalopathy of childhood with neurodegeneration in adulthood. Nat Genet (2013) 4.71
Autophagy-deficient mice develop multiple liver tumors. Genes Dev (2011) 4.64
Essential roles of Atg5 and FADD in autophagic cell death: dissection of autophagic cell death into vacuole formation and cell death. J Biol Chem (2005) 4.56
The hairpin-type tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomes. Cell (2012) 4.40
Formation of the approximately 350-kDa Apg12-Apg5.Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast. J Biol Chem (2002) 4.27
Tissue-specific autophagy alterations and increased tumorigenesis in mice deficient in Atg4C/autophagin-3. J Biol Chem (2007) 4.22
Autophagosome-independent essential function for the autophagy protein Atg5 in cellular immunity to intracellular pathogens. Cell Host Microbe (2008) 4.16
The dynamics of autophagy visualized in live cells: from autophagosome formation to fusion with endo/lysosomes. Autophagy (2005) 4.08
Atg17 functions in cooperation with Atg1 and Atg13 in yeast autophagy. Mol Biol Cell (2005) 4.02
Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins. Autophagy (2010) 3.99
LC3, an autophagosome marker, can be incorporated into protein aggregates independent of autophagy: caution in the interpretation of LC3 localization. Autophagy (2007) 3.91
Regulation of intracellular accumulation of mutant Huntingtin by Beclin 1. J Biol Chem (2006) 3.77
The Atg8 conjugation system is indispensable for proper development of autophagic isolation membranes in mice. Mol Biol Cell (2008) 3.72
Molecular machinery of autophagosome formation in yeast, Saccharomyces cerevisiae. FEBS Lett (2007) 3.65
Autophagy is essential for preimplantation development of mouse embryos. Science (2008) 3.55
Generation of cell lines with tetracycline-regulated autophagy and a role for autophagy in controlling cell size. FEBS Lett (2006) 3.49
Leaf senescence and starvation-induced chlorosis are accelerated by the disruption of an Arabidopsis autophagy gene. Plant Physiol (2002) 3.47
Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice. J Clin Invest (2010) 3.44
Induction of autophagy in axonal dystrophy and degeneration. J Neurosci (2006) 3.28
Structural basis of target recognition by Atg8/LC3 during selective autophagy. Genes Cells (2008) 3.23
In vivo requirement for Atg5 in antigen presentation by dendritic cells. Immunity (2010) 3.19
Cerebral ischemia-hypoxia induces intravascular coagulation and autophagy. Am J Pathol (2006) 3.18
Processing of ATG8s, ubiquitin-like proteins, and their deconjugation by ATG4s are essential for plant autophagy. Plant Cell (2004) 3.17
Lectin affinity capture, isotope-coded tagging and mass spectrometry to identify N-linked glycoproteins. Nat Biotechnol (2003) 3.15
Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance. Nature (2008) 3.09
Two ubiquitin-like conjugation systems essential for autophagy. Semin Cell Dev Biol (2004) 3.04
DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics. Mol Cell Biol (2007) 3.03
The origin of planetary impactors in the inner solar system. Science (2005) 3.01
Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane. J Biol Chem (2011) 2.99
Coronavirus replication complex formation utilizes components of cellular autophagy. J Biol Chem (2003) 2.96
Tor directly controls the Atg1 kinase complex to regulate autophagy. Mol Cell Biol (2009) 2.86
Atg8-family interacting motif crucial for selective autophagy. FEBS Lett (2010) 2.83
A sensitive and quantitative technique for detecting autophagic events based on lysosomal delivery. Chem Biol (2011) 2.81
Atg101, a novel mammalian autophagy protein interacting with Atg13. Autophagy (2009) 2.78
Yeast autophagosomes: de novo formation of a membrane structure. Trends Cell Biol (2002) 2.69
A crucial role for adipose tissue p53 in the regulation of insulin resistance. Nat Med (2009) 2.65
Autophagy is required for maintenance of amino acid levels and protein synthesis under nitrogen starvation. J Biol Chem (2005) 2.64
Assortment of phosphatidylinositol 3-kinase complexes--Atg14p directs association of complex I to the pre-autophagosomal structure in Saccharomyces cerevisiae. Mol Biol Cell (2006) 2.63
Intracellular inclusions containing mutant alpha1-antitrypsin Z are propagated in the absence of autophagic activity. J Biol Chem (2005) 2.60
A comprehensive analysis of allelic methylation status of CpG islands on human chromosome 21q. Genome Res (2004) 2.56
Participation of autophagy in storage of lysosomes in neurons from mouse models of neuronal ceroid-lipofuscinoses (Batten disease). Am J Pathol (2005) 2.56
Organization of the pre-autophagosomal structure responsible for autophagosome formation. Mol Biol Cell (2008) 2.49
Identification of Ser-386 of interferon regulatory factor 3 as critical target for inducible phosphorylation that determines activation. J Biol Chem (2003) 2.45
Tor2 directly phosphorylates the AGC kinase Ypk2 to regulate actin polarization. Mol Cell Biol (2005) 2.44
Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes. J Cell Sci (2004) 2.35
Autophagy negatively regulates cell death by controlling NPR1-dependent salicylic acid signaling during senescence and the innate immune response in Arabidopsis. Plant Cell (2009) 2.32
Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selection. J Cell Biol (2010) 2.32
The structure of Atg4B-LC3 complex reveals the mechanism of LC3 processing and delipidation during autophagy. EMBO J (2009) 2.25
In vivo and in vitro reconstitution of Atg8 conjugation essential for autophagy. J Biol Chem (2004) 2.21
Structure of Atg5.Atg16, a complex essential for autophagy. J Biol Chem (2006) 2.18
Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue. Mol Brain (2012) 2.18
A direct nanoflow liquid chromatography-tandem mass spectrometry system for interaction proteomics. Anal Chem (2002) 2.18
p62 Targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding. J Cell Biol (2011) 2.16
Suppression of autophagy in skeletal muscle uncovers the accumulation of ubiquitinated proteins and their potential role in muscle damage in Pompe disease. Hum Mol Genet (2008) 2.15
Constitutive activation of chaperone-mediated autophagy in cells with impaired macroautophagy. Mol Biol Cell (2008) 2.14
Living donor liver transplantation: the Asian perspective. Transplantation (2014) 2.13
Atg9 vesicles are an important membrane source during early steps of autophagosome formation. J Cell Biol (2012) 2.12
AtATG genes, homologs of yeast autophagy genes, are involved in constitutive autophagy in Arabidopsis root tip cells. Plant Cell Physiol (2006) 2.06