Identification of anthrax toxin genes in a Bacillus cereus associated with an illness resembling inhalation anthrax.

PubWeight™: 4.73‹?› | Rank: Top 1%

🔗 View Article (PMC 420414)

Published in Proc Natl Acad Sci U S A on May 21, 2004

Authors

Alex R Hoffmaster1, Jacques Ravel, David A Rasko, Gail D Chapman, Michael D Chute, Chung K Marston, Barun K De, Claudio T Sacchi, Collette Fitzgerald, Leonard W Mayer, Martin C J Maiden, Fergus G Priest, Margaret Barker, Lingxia Jiang, Regina Z Cer, Jennifer Rilstone, Scott N Peterson, Robbin S Weyant, Darrell R Galloway, Timothy D Read, Tanja Popovic, Claire M Fraser

Author Affiliations

1: Epidemiologic Investigations Laboratory, Meningitis and Special Pathogens Branch, Centers for Disease Control and Prevention, 1600 Clifton Road, MS G34, Atlanta, GA 30333, USA.

Articles citing this

(truncated to the top 100)

Genomic insights that advance the species definition for prokaryotes. Proc Natl Acad Sci U S A (2005) 9.63

Who ate whom? Adaptive Helicobacter genomic changes that accompanied a host jump from early humans to large felines. PLoS Genet (2006) 4.65

The bacterial species definition in the genomic era. Philos Trans R Soc Lond B Biol Sci (2006) 4.47

Visualization of comparative genomic analyses by BLAST score ratio. BMC Bioinformatics (2005) 3.54

Bacillus cereus, a volatile human pathogen. Clin Microbiol Rev (2010) 3.33

Pathogenomic sequence analysis of Bacillus cereus and Bacillus thuringiensis isolates closely related to Bacillus anthracis. J Bacteriol (2006) 3.23

Characterization of Bacillus cereus isolates associated with fatal pneumonias: strains are closely related to Bacillus anthracis and harbor B. anthracis virulence genes. J Clin Microbiol (2006) 3.15

Microbial threat lists: obstacles in the quest for biosecurity? Nat Rev Microbiol (2010) 2.63

Genotyping of Bacillus anthracis strains based on automated capillary 25-loci multiple locus variable-number tandem repeats analysis. BMC Microbiol (2006) 2.22

The genome of a Bacillus isolate causing anthrax in chimpanzees combines chromosomal properties of B. cereus with B. anthracis virulence plasmids. PLoS One (2010) 1.91

Characterization of Bacillus anthracis-like bacteria isolated from wild great apes from Cote d'Ivoire and Cameroon. J Bacteriol (2006) 1.77

Complete sequence analysis of novel plasmids from emetic and periodontal Bacillus cereus isolates reveals a common evolutionary history among the B. cereus-group plasmids, including Bacillus anthracis pXO1. J Bacteriol (2006) 1.70

Phylogeny in aid of the present and novel microbial lineages: diversity in Bacillus. PLoS One (2009) 1.62

Microarray-based resequencing of multiple Bacillus anthracis isolates. Genome Biol (2004) 1.61

A novel FtsZ-like protein is involved in replication of the anthrax toxin-encoding pXO1 plasmid in Bacillus anthracis. J Bacteriol (2006) 1.54

Capsules, toxins and AtxA as virulence factors of emerging Bacillus cereus biovar anthracis. PLoS Negl Trop Dis (2015) 1.51

Nucleation of platelets with blood-borne pathogens on Kupffer cells precedes other innate immunity and contributes to bacterial clearance. Nat Immunol (2013) 1.46

Bacillus anthracis multiplication, persistence, and genetic exchange in the rhizosphere of grass plants. Appl Environ Microbiol (2006) 1.42

Human monoclonal antibodies against anthrax lethal factor and protective antigen act independently to protect against Bacillus anthracis infection and enhance endogenous immunity to anthrax. Infect Immun (2007) 1.40

Genome-wide single nucleotide polymorphism typing method for identification of Bacillus anthracis species and strains among B. cereus group species. J Clin Microbiol (2010) 1.38

Genomic characterization of the Bacillus cereus sensu lato species: backdrop to the evolution of Bacillus anthracis. Genome Res (2012) 1.37

Bacillus anthracis physiology and genetics. Mol Aspects Med (2009) 1.29

Distribution, diversity, and potential mobility of extrachromosomal elements related to the Bacillus anthracis pXO1 and pXO2 virulence plasmids. Appl Environ Microbiol (2009) 1.29

Characterization of sporulation histidine kinases of Bacillus anthracis. J Bacteriol (2005) 1.28

Conjugative plasmid pAW63 brings new insights into the genesis of the Bacillus anthracis virulence plasmid pXO2 and of the Bacillus thuringiensis plasmid pBT9727. BMC Genomics (2005) 1.28

Reliable detection of Bacillus anthracis, Francisella tularensis and Yersinia pestis by using multiplex qPCR including internal controls for nucleic acid extraction and amplification. BMC Microbiol (2010) 1.25

The genome and variation of Bacillus anthracis. Mol Aspects Med (2009) 1.23

Rap phosphatase of virulence plasmid pXO1 inhibits Bacillus anthracis sporulation. J Bacteriol (2006) 1.23

The InhA metalloproteases of Bacillus cereus contribute concomitantly to virulence. J Bacteriol (2010) 1.21

A new Bacillus anthracis found in wild chimpanzees and a gorilla from West and Central Africa. PLoS Pathog (2006) 1.19

Genetic diversity of clinical isolates of Bacillus cereus using multilocus sequence typing. BMC Microbiol (2008) 1.17

Molecular basis for group-specific activation of the virulence regulator PlcR by PapR heptapeptides. Nucleic Acids Res (2008) 1.16

Microbial virulence as an emergent property: consequences and opportunities. PLoS Pathog (2011) 1.16

Using Mahalanobis distance to compare genomic signatures between bacterial plasmids and chromosomes. Nucleic Acids Res (2008) 1.14

BslA, the S-layer adhesin of B. anthracis, is a virulence factor for anthrax pathogenesis. Mol Microbiol (2009) 1.14

Anthrax, but not Bacillus anthracis? PLoS Pathog (2006) 1.13

Comparative transcriptional profiling of Bacillus cereus sensu lato strains during growth in CO2-bicarbonate and aerobic atmospheres. PLoS One (2009) 1.11

Two capsular polysaccharides enable Bacillus cereus G9241 to cause anthrax-like disease. Mol Microbiol (2011) 1.11

InhA1, NprA, and HlyII as candidates for markers to differentiate pathogenic from nonpathogenic Bacillus cereus strains. J Clin Microbiol (2010) 1.10

Specificity and polymorphism of the PlcR-PapR quorum-sensing system in the Bacillus cereus group. J Bacteriol (2005) 1.09

Identification and functional characterization of the Lactococcus lactis CodY-regulated branched-chain amino acid permease BcaP (CtrA). J Bacteriol (2006) 1.09

Molecular approaches to identify and differentiate Bacillus anthracis from phenotypically similar Bacillus species isolates. BMC Microbiol (2006) 1.09

The Bacillus anthracis chromosome contains four conserved, excision-proficient, putative prophages. BMC Microbiol (2006) 1.09

A new minimal replicon of Bacillus anthracis plasmid pXO1. J Bacteriol (2009) 1.08

Survey of group I and group II introns in 29 sequenced genomes of the Bacillus cereus group: insights into their spread and evolution. Nucleic Acids Res (2008) 1.08

IlsA, a unique surface protein of Bacillus cereus required for iron acquisition from heme, hemoglobin and ferritin. PLoS Pathog (2009) 1.08

Secondary cell wall polysaccharides from Bacillus cereus strains G9241, 03BB87 and 03BB102 causing fatal pneumonia share similar glycosyl structures with the polysaccharides from Bacillus anthracis. Glycobiology (2011) 1.07

Induction of natural competence in Bacillus cereus ATCC14579. Microb Biotechnol (2008) 1.07

Cell wall carbohydrate compositions of strains from the Bacillus cereus group of species correlate with phylogenetic relatedness. J Bacteriol (2007) 1.07

Multiplexed detection of anthrax-related toxin genes. J Mol Diagn (2006) 1.05

Unusual group II introns in bacteria of the Bacillus cereus group. J Bacteriol (2005) 1.05

Structural elucidation of the nonclassical secondary cell wall polysaccharide from Bacillus cereus ATCC 10987. Comparison with the polysaccharides from Bacillus anthracis and B. cereus type strain ATCC 14579 reveals both unique and common structural features. J Biol Chem (2008) 1.05

A Genomic View of Lactobacilli and Pediococci Demonstrates that Phylogeny Matches Ecology and Physiology. Appl Environ Microbiol (2015) 1.04

Air-liquid interface biofilms of Bacillus cereus: formation, sporulation, and dispersion. Appl Environ Microbiol (2007) 1.04

Sensor domains encoded in Bacillus anthracis virulence plasmids prevent sporulation by hijacking a sporulation sensor histidine kinase. J Bacteriol (2006) 1.04

Photodynamic inactivation of Bacillus spores, mediated by phenothiazinium dyes. Appl Environ Microbiol (2005) 1.02

Capsule production in Bacillus cereus strains associated with severe pneumonia. J Clin Microbiol (2006) 1.02

Rapid identification of genetic modifications in Bacillus anthracis using whole genome draft sequences generated by 454 pyrosequencing. PLoS One (2010) 0.99

Genetic diversity in a Bacillus anthracis historical collection (1954 to 1988). J Clin Microbiol (2007) 0.98

Anthrax: A disease of biowarfare and public health importance. World J Clin Cases (2015) 0.97

Massive horizontal gene transfer, strictly vertical inheritance and ancient duplications differentially shape the evolution of Bacillus cereus enterotoxin operons hbl, cytK and nhe. BMC Evol Biol (2015) 0.97

Plasmid-encoded regulator of extracellular proteases in Bacillus anthracis. J Bacteriol (2005) 0.97

Structure-activity relationships of Bacillus cereus and Bacillus anthracis dihydrofolate reductase: toward the identification of new potent drug leads. Antimicrob Agents Chemother (2006) 0.97

The early humoral immune response to Bacillus anthracis toxins in patients infected with cutaneous anthrax. FEMS Immunol Med Microbiol (2011) 0.97

The tubulin-like RepX protein encoded by the pXO1 plasmid forms polymers in vivo in Bacillus anthracis. J Bacteriol (2009) 0.96

Effective antiprotease-antibiotic treatment of experimental anthrax. BMC Infect Dis (2005) 0.96

Cholera- and anthrax-like toxins are among several new ADP-ribosyltransferases. PLoS Comput Biol (2010) 0.96

An attenuated strain of Bacillus anthracis (CDC 684) has a large chromosomal inversion and altered growth kinetics. BMC Genomics (2011) 0.96

Secondary cell wall polysaccharides of Bacillus anthracis are antigens that contain specific epitopes which cross-react with three pathogenic Bacillus cereus strains that caused severe disease, and other epitopes common to all the Bacillus cereus strains tested. Glycobiology (2009) 0.95

Clinical detection and characterization of bacterial pathogens in the genomics era. Genome Med (2014) 0.94

Environmental factors determining the epidemiology and population genetic structure of the Bacillus cereus group in the field. PLoS Pathog (2010) 0.94

Bacillus cereus Biovar Anthracis Causing Anthrax in Sub-Saharan Africa-Chromosomal Monophyly and Broad Geographic Distribution. PLoS Negl Trop Dis (2016) 0.92

Seasonal trend and clinical presentation of Bacillus cereus bloodstream infection: association with summer and indwelling catheter. Eur J Clin Microbiol Infect Dis (2014) 0.91

Comparison of minisatellite polymorphisms in the Bacillus cereus complex: a simple assay for large-scale screening and identification of strains most closely related to Bacillus anthracis. Appl Environ Microbiol (2005) 0.91

Global mRNA decay analysis at single nucleotide resolution reveals segmental and positional degradation patterns in a Gram-positive bacterium. Genome Biol (2012) 0.91

In silico and in vitro evaluation of PCR-based assays for the detection of Bacillus anthracis chromosomal signature sequences. Virulence (2013) 0.91

Development and comparison of two assay formats for parallel detection of four biothreat pathogens by using suspension microarrays. PLoS One (2012) 0.90

An extracytoplasmic function sigma factor controls beta-lactamase gene expression in Bacillus anthracis and other Bacillus cereus group species. J Bacteriol (2009) 0.90

Immunotoxicology of arc welding fume: worker and experimental animal studies. J Immunotoxicol (2012) 0.88

The Microbial Rosetta Stone: a database system for tracking infectious microorganisms. Int J Legal Med (2008) 0.88

Anthrax Toxin-Expressing Bacillus cereus Isolated from an Anthrax-Like Eschar. PLoS One (2016) 0.87

Transcriptome analysis identifies Bacillus anthracis genes that respond to CO2 through an AtxA-dependent mechanism. BMC Genomics (2014) 0.87

The pore-forming protein Cry5B elicits the pathogenicity of Bacillus sp. against Caenorhabditis elegans. PLoS One (2011) 0.87

An anthrax subunit vaccine candidate based on protective regions of Bacillus anthracis protective antigen and lethal factor. Vaccine (2010) 0.87

Genotyping of Bacillus cereus strains by microarray-based resequencing. PLoS One (2008) 0.87

Discrimination of Bacillus anthracis and closely related microorganisms by analysis of 16S and 23S rRNA with oligonucleotide microarray. Chem Biol Interact (2007) 0.86

Bacillus cereus G9241 makes anthrax toxin and capsule like highly virulent B. anthracis Ames but behaves like attenuated toxigenic nonencapsulated B. anthracis Sterne in rabbits and mice. Infect Immun (2011) 0.86

Clostridial binary toxins: iota and C2 family portraits. Front Cell Infect Microbiol (2011) 0.86

Identification of Bacillus anthracis spore component antigens conserved across diverse Bacillus cereus sensu lato strains. Mol Cell Proteomics (2009) 0.85

Reverse line blot macroarray for simultaneous detection and characterization of four biological warfare agents. Indian J Microbiol (2012) 0.85

Expression of transcription activator ComK of Bacillus subtilis in the heterologous host Lactococcus lactis leads to a genome-wide repression pattern: a case study of horizontal gene transfer. Appl Environ Microbiol (2006) 0.84

Activation of the latent PlcR regulon in Bacillus anthracis. Microbiology (2010) 0.84

Differentiation of Bacillus anthracis, B. cereus, and B. thuringiensis by using pulsed-field gel electrophoresis. Appl Environ Microbiol (2007) 0.84

Strategy for identification of Bacillus cereus and Bacillus thuringiensis strains closely related to Bacillus anthracis. Appl Environ Microbiol (2006) 0.84

Structures of a bifunctional cell wall hydrolase CwlT containing a novel bacterial lysozyme and an NlpC/P60 DL-endopeptidase. J Mol Biol (2013) 0.83

Investigating the genome diversity of B. cereus and evolutionary aspects of B. anthracis emergence. Genomics (2011) 0.83

Characterization of an environmental strain of Bacillus thuringiensis from a hot spring in Western Himalayas. Curr Microbiol (2010) 0.82

Phase 1 study of a recombinant mutant protective antigen of Bacillus anthracis. Clin Vaccine Immunol (2011) 0.82

Rapid focused sequencing: a multiplexed assay for simultaneous detection and strain typing of Bacillus anthracis, Francisella tularensis, and Yersinia pestis. PLoS One (2013) 0.82

Certhrax toxin, an anthrax-related ADP-ribosyltransferase from Bacillus cereus. J Biol Chem (2012) 0.82

Articles cited by this

The neighbor-joining method: a new method for reconstructing phylogenetic trees. Mol Biol Evol (1987) 266.90

A whole-genome assembly of Drosophila. Science (2000) 38.48

The Genome sequence of the SARS-associated coronavirus. Science (2003) 16.68

Bioterrorism-related inhalational anthrax: the first 10 cases reported in the United States. Emerg Infect Dis (2001) 11.73

The Comprehensive Microbial Resource. Nucleic Acids Res (2001) 11.19

The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria. Nature (2003) 10.38

Demonstration of a capsule plasmid in Bacillus anthracis. Infect Immun (1985) 8.46

Bacillus anthracis, Bacillus cereus, and Bacillus thuringiensis--one species on the basis of genetic evidence. Appl Environ Microbiol (2000) 7.87

Genome sequence of Bacillus cereus and comparative analysis with Bacillus anthracis. Nature (2003) 7.05

Molecular evolution and diversity in Bacillus anthracis as detected by amplified fragment length polymorphism markers. J Bacteriol (1997) 6.93

Investigation of bioterrorism-related anthrax, United States, 2001: epidemiologic findings. Emerg Infect Dis (2002) 5.23

Sequence and organization of pXO1, the large Bacillus anthracis plasmid harboring the anthrax toxin genes. J Bacteriol (1999) 4.50

Genome sequence of Chlamydophila caviae (Chlamydia psittaci GPIC): examining the role of niche-specific genes in the evolution of the Chlamydiaceae. Nucleic Acids Res (2003) 4.33

The genome sequence of Bacillus cereus ATCC 10987 reveals metabolic adaptations and a large plasmid related to Bacillus anthracis pXO1. Nucleic Acids Res (2004) 3.62

PlcR is a pleiotropic regulator of extracellular virulence factor gene expression in Bacillus thuringiensis. Mol Microbiol (1999) 3.43

Genetic diversity in the protective antigen gene of Bacillus anthracis. J Bacteriol (1999) 2.92

Fluorescent Amplified Fragment Length Polymorphism Analysis of Norwegian Bacillus cereus and Bacillus thuringiensis Soil Isolates. Appl Environ Microbiol (2001) 2.85

Specific identification of Bacillus anthracis by means of a variant bacteriophage. J Infect Dis (1955) 2.74

Sequencing of 16S rRNA gene: a rapid tool for identification of Bacillus anthracis. Emerg Infect Dis (2002) 2.54

Sequence, assembly and analysis of pX01 and pX02. J Appl Microbiol (1999) 2.53

The incompatibility between the PlcR- and AtxA-controlled regulons may have selected a nonsense mutation in Bacillus anthracis. Mol Microbiol (2001) 2.20

Bacillus anthracis pXO1 plasmid sequence conservation among closely related bacterial species. J Bacteriol (2002) 2.11

Homoduplex and heteroduplex polymorphisms of the amplified ribosomal 16S-23S internal transcribed spacers describe genetic relationships in the "Bacillus cereus group". Appl Environ Microbiol (2000) 1.97

Fulminating bacteremia and pneumonia due to Bacillus cereus. J Clin Microbiol (1997) 1.75

Passive transfer of protection against Bacillus anthracis infection in a murine model. Vaccine (2001) 1.60

Mapping dominant-negative mutations of anthrax protective antigen by scanning mutagenesis. Proc Natl Acad Sci U S A (2003) 1.59

A two-component direct fluorescent-antibody assay for rapid identification of Bacillus anthracis. Emerg Infect Dis (2002) 1.54

DNA sequence conservation between the Bacillus anthracis pXO2 plasmid and genomic sequence from closely related bacteria. BMC Genomics (2002) 1.34

Genetic relationship in the 'Bacillus cereus group' by rep-PCR fingerprinting and sequencing of a Bacillus anthracis-specific rep-PCR fragment. J Appl Microbiol (2003) 1.30

Production of diarrheal enterotoxins and other potential virulence factors by veterinary isolates of bacillus species associated with nongastrointestinal infections. Appl Environ Microbiol (2003) 1.12

Articles by these authors

Genome sequence of the human malaria parasite Plasmodium falciparum. Nature (2002) 37.89

Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Nature (2004) 24.40

The genome sequence of the malaria mosquito Anopheles gambiae. Science (2002) 20.36

Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: implications for the microbial "pan-genome". Proc Natl Acad Sci U S A (2005) 14.59

Sex and virulence in Escherichia coli: an evolutionary perspective. Mol Microbiol (2006) 14.53

Large-scale sequencing of human influenza reveals the dynamic nature of viral genome evolution. Nature (2005) 11.99

The genome of the African trypanosome Trypanosoma brucei. Science (2005) 11.48

Report of the ad hoc committee for the re-evaluation of the species definition in bacteriology. Int J Syst Evol Microbiol (2002) 11.02

The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria. Nature (2003) 10.38

Hybrid error correction and de novo assembly of single-molecule sequencing reads. Nat Biotechnol (2012) 10.31

Comparative genome sequencing for discovery of novel polymorphisms in Bacillus anthracis. Science (2002) 9.83

BIGSdb: Scalable analysis of bacterial genome variation at the population level. BMC Bioinformatics (2010) 9.30

Genome sequence and comparative analysis of the model rodent malaria parasite Plasmodium yoelii yoelii. Nature (2002) 8.92

Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain. J Bacteriol (2005) 8.72

The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease. Science (2005) 7.61

Minimum information about a marker gene sequence (MIMARKS) and minimum information about any (x) sequence (MIxS) specifications. Nat Biotechnol (2011) 7.53

Genome sequence of the dissimilatory metal ion-reducing bacterium Shewanella oneidensis. Nat Biotechnol (2002) 6.96

mlstdbNet - distributed multi-locus sequence typing (MLST) databases. BMC Bioinformatics (2004) 6.75

Moving pictures of the human microbiome. Genome Biol (2011) 6.72

Multi-locus sequence typing: a tool for global epidemiology. Trends Microbiol (2003) 6.23

The pangenome structure of Escherichia coli: comparative genomic analysis of E. coli commensal and pathogenic isolates. J Bacteriol (2008) 6.02

Phylogenetic discovery bias in Bacillus anthracis using single-nucleotide polymorphisms from whole-genome sequencing. Proc Natl Acad Sci U S A (2004) 5.98

The dog genome: survey sequencing and comparative analysis. Science (2003) 5.84

The complete genome sequence of the Arabidopsis and tomato pathogen Pseudomonas syringae pv. tomato DC3000. Proc Natl Acad Sci U S A (2003) 5.62

Whole-genome analysis of human influenza A virus reveals multiple persistent lineages and reassortment among recent H3N2 viruses. PLoS Biol (2005) 5.48

The genome of the protist parasite Entamoeba histolytica. Nature (2005) 5.33

Complete genome sequence and comparative genomic analysis of an emerging human pathogen, serotype V Streptococcus agalactiae. Proc Natl Acad Sci U S A (2002) 5.28

The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts. Proc Natl Acad Sci U S A (2002) 5.28

Investigation of bioterrorism-related anthrax, United States, 2001: epidemiologic findings. Emerg Infect Dis (2002) 5.23

Major structural differences and novel potential virulence mechanisms from the genomes of multiple campylobacter species. PLoS Biol (2005) 5.22

Patellamide A and C biosynthesis by a microcin-like pathway in Prochloron didemni, the cyanobacterial symbiont of Lissoclinum patella. Proc Natl Acad Sci U S A (2005) 5.02

Genome sequence of Silicibacter pomeroyi reveals adaptations to the marine environment. Nature (2004) 5.00

A physical map of the mouse genome. Nature (2002) 4.97

Whole genome comparisons of serotype 4b and 1/2a strains of the food-borne pathogen Listeria monocytogenes reveal new insights into the core genome components of this species. Nucleic Acids Res (2004) 4.97

Global genetic population structure of Bacillus anthracis. PLoS One (2007) 4.94

The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans. Science (2005) 4.74

Complete genome sequence of the plant commensal Pseudomonas fluorescens Pf-5. Nat Biotechnol (2005) 4.65

Temporal dynamics of the human vaginal microbiota. Sci Transl Med (2012) 4.58

Characterization of encapsulated and noncapsulated Haemophilus influenzae and determination of phylogenetic relationships by multilocus sequence typing. J Clin Microbiol (2003) 4.47

Evaluation and improvement of real-time PCR assays targeting lytA, ply, and psaA genes for detection of pneumococcal DNA. J Clin Microbiol (2007) 4.44

Complete genome sequence of the oral pathogenic Bacterium porphyromonas gingivalis strain W83. J Bacteriol (2003) 4.41

Yersinia pestis genome sequencing identifies patterns of global phylogenetic diversity. Nat Genet (2010) 4.35

Multiple antimicrobial resistance in plague: an emerging public health risk. PLoS One (2007) 4.21

Complete genome sequence of the Q-fever pathogen Coxiella burnetii. Proc Natl Acad Sci U S A (2003) 4.20

Unsuspected diversity among marine aerobic anoxygenic phototrophs. Nature (2002) 4.14

Structural flexibility in the Burkholderia mallei genome. Proc Natl Acad Sci U S A (2004) 4.13

Natural combinatorial peptide libraries in cyanobacterial symbionts of marine ascidians. Nat Chem Biol (2006) 4.12

Molecular characterization of Campylobacter jejuni clones: a basis for epidemiologic investigation. Emerg Infect Dis (2002) 3.98

Candida orthopsilosis and Candida metapsilosis spp. nov. to replace Candida parapsilosis groups II and III. J Clin Microbiol (2005) 3.93

The genome sequence of Bacillus cereus ATCC 10987 reveals metabolic adaptations and a large plasmid related to Bacillus anthracis pXO1. Nucleic Acids Res (2004) 3.62

Changes in Neisseria meningitidis disease epidemiology in the United States, 1998-2007: implications for prevention of meningococcal disease. Clin Infect Dis (2010) 3.61

Visualization of comparative genomic analyses by BLAST score ratio. BMC Bioinformatics (2005) 3.54

Metagenomics: read length matters. Appl Environ Microbiol (2008) 3.51

Multilocus sequence typing system for the endosymbiont Wolbachia pipientis. Appl Environ Microbiol (2006) 3.45

The genome sequence of the anaerobic, sulfate-reducing bacterium Desulfovibrio vulgaris Hildenborough. Nat Biotechnol (2004) 3.43

Fatal inhalational anthrax in a 94-year-old Connecticut woman. JAMA (2002) 3.26

Genomics of the Bacillus cereus group of organisms. FEMS Microbiol Rev (2005) 3.23

The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic, anaerobic, green-sulfur bacterium. Proc Natl Acad Sci U S A (2002) 3.19

A global assembly line for cyanobactins. Nat Chem Biol (2008) 3.17

Characterization of Bacillus cereus isolates associated with fatal pneumonias: strains are closely related to Bacillus anthracis and harbor B. anthracis virulence genes. J Clin Microbiol (2006) 3.15

The psychrophilic lifestyle as revealed by the genome sequence of Colwellia psychrerythraea 34H through genomic and proteomic analyses. Proc Natl Acad Sci U S A (2005) 3.10

Genome sequence of the PCE-dechlorinating bacterium Dehalococcoides ethenogenes. Science (2005) 3.10

Population structure and evolution of the Bacillus cereus group. J Bacteriol (2004) 3.08

PorA variable regions of Neisseria meningitidis. Emerg Infect Dis (2004) 3.08

Genomic diversity of 2010 Haitian cholera outbreak strains. Proc Natl Acad Sci U S A (2012) 3.04

Evaluation of four commercially available rapid serologic tests for diagnosis of leptospirosis. J Clin Microbiol (2003) 3.01

Molecular subtyping of Bacillus anthracis and the 2001 bioterrorism-associated anthrax outbreak, United States. Emerg Infect Dis (2002) 2.99

Chapter 8. Methods for in silico prediction of microbial polyketide and nonribosomal peptide biosynthetic pathways from DNA sequence data. Methods Enzymol (2009) 2.93

TLR signaling is required for Salmonella typhimurium virulence. Cell (2011) 2.88

Sequence typing and comparison of population biology of Campylobacter coli and Campylobacter jejuni. J Clin Microbiol (2005) 2.88

Outbreak of W135 meningococcal disease in 2000: not emergence of a new W135 strain but clonal expansion within the electophoretic type-37 complex. J Infect Dis (2002) 2.88

Phylogenomics: intersection of evolution and genomics. Science (2003) 2.86

Skewed genomic variability in strains of the toxigenic bacterial pathogen, Clostridium perfringens. Genome Res (2006) 2.84