Published in J Allergy Clin Immunol on July 01, 2004
E-prostanoid 2 receptors dampen mast cell degranulation via cAMP/PKA-mediated suppression of IgE-dependent signaling. J Leukoc Biol (2012) 1.47
Functional KCa3.1 K+ channels are required for human lung mast cell migration. Thorax (2006) 1.39
Regulation of Ca2+ signaling with particular focus on mast cells. Crit Rev Immunol (2009) 1.20
The Quintiles Prize Lecture 2004. The identification of the adenosine A2B receptor as a novel therapeutic target in asthma. Br J Pharmacol (2005) 1.08
The K+ channels K(Ca)3.1 and K(v)1.3 as novel targets for asthma therapy. Br J Pharmacol (2009) 1.08
Endothelial small-conductance and intermediate-conductance KCa channels: an update on their pharmacology and usefulness as cardiovascular targets. J Cardiovasc Pharmacol (2013) 1.05
Adenosine closes the K+ channel KCa3.1 in human lung mast cells and inhibits their migration via the adenosine A2A receptor. Eur J Immunol (2007) 1.04
Chemokines and their receptors as potential targets for the treatment of asthma. Br J Pharmacol (2007) 1.01
The Lymphocyte Potassium Channels Kv1.3 and KCa3.1 as Targets for Immunosuppression. Drug Dev Res (2011) 0.98
CRACM/Orai ion channel expression and function in human lung mast cells. J Allergy Clin Immunol (2012) 0.96
Functional KCa3.1 K+ channels are required for human fibrocyte migration. J Allergy Clin Immunol (2011) 0.95
Regulation and function of the two-pore-domain (K2P) potassium channel Trek-1 in alveolar epithelial cells. Am J Physiol Lung Cell Mol Physiol (2011) 0.92
Phosphatidylinositol-3-kinase C2β and TRIM27 function to positively and negatively regulate IgE receptor activation of mast cells. Mol Cell Biol (2012) 0.92
IgE-dependent signaling as a therapeutic target for allergies. Trends Pharmacol Sci (2012) 0.92
The K+ channel KCa3.1 as a novel target for idiopathic pulmonary fibrosis. PLoS One (2013) 0.92
Engagement of the EP2 prostanoid receptor closes the K+ channel KCa3.1 in human lung mast cells and attenuates their migration. Eur J Immunol (2008) 0.89
Ca(2+)-activated K(+) channel-3.1 blocker TRAM-34 attenuates airway remodeling and eosinophilia in a murine asthma model. Am J Respir Cell Mol Biol (2012) 0.88
K(Ca)3.1 channel-blockade attenuates airway pathophysiology in a sheep model of chronic asthma. PLoS One (2013) 0.84
Human lung myofibroblast TGFβ1-dependent Smad2/3 signalling is Ca(2+)-dependent and regulated by KCa3.1 K(+) channels. Fibrogenesis Tissue Repair (2015) 0.82
Serum- and glucocorticoid-inducible kinase 1 in the regulation of renal and extrarenal potassium transport. Clin Exp Nephrol (2011) 0.79
Blunted IgE-mediated activation of mast cells in mice lacking the serum- and glucocorticoid-inducible kinase SGK3. Am J Physiol Cell Physiol (2010) 0.79
Systemic effects of ingested Lactobacillus rhamnosus: inhibition of mast cell membrane potassium (IKCa) current and degranulation. PLoS One (2012) 0.78
Sphingosine-1-phosphate can promote mast cell hyper-reactivity through regulation of contactin-4 expression. J Leukoc Biol (2013) 0.78
Orai/CRACM1 and KCa3.1 ion channels interact in the human lung mast cell plasma membrane. Cell Commun Signal (2015) 0.76
KCa3.1 K+ Channel Expression and Function in Human Bronchial Epithelial Cells. PLoS One (2015) 0.76
The role of stretch-activated ion channels in acute respiratory distress syndrome: finally a new target? Am J Physiol Lung Cell Mol Physiol (2016) 0.75
Evidence for a novel Kit adhesion domain mediating human mast cell adhesion to structural airway cells. Respir Res (2015) 0.75
Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial. Lancet (2002) 8.57
Mepolizumab and exacerbations of refractory eosinophilic asthma. N Engl J Med (2009) 8.36
Mast-cell infiltration of airway smooth muscle in asthma. N Engl J Med (2002) 6.52
Elevated sputum interleukin-5 and submucosal eosinophilia in obese individuals with severe asthma. Am J Respir Crit Care Med (2013) 4.95
Evidence of a role of tumor necrosis factor alpha in refractory asthma. N Engl J Med (2006) 4.83
Stress-induced apoptosis associated with null mutation of ADAR1 RNA editing deaminase gene. J Biol Chem (2003) 3.93
Role of YKL-40 in bronchial smooth muscle remodeling in asthma. Am J Respir Crit Care Med (2012) 2.53
Pathological features and inhaled corticosteroid response of eosinophilic and non-eosinophilic asthma. Thorax (2007) 2.37
Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients. J Allergy Clin Immunol (2012) 2.24
Vibratory Urticaria Associated with a Missense Variant in ADGRE2. N Engl J Med (2016) 2.09
Cold urticaria, immunodeficiency, and autoimmunity related to PLCG2 deletions. N Engl J Med (2012) 2.08
Induced sputum inflammatory mediator concentrations in chronic cough. Am J Respir Crit Care Med (2003) 1.98
The CXCL10/CXCR3 axis mediates human lung mast cell migration to asthmatic airway smooth muscle. Am J Respir Crit Care Med (2005) 1.95
Requirement of dimerization for RNA editing activity of adenosine deaminases acting on RNA. J Biol Chem (2003) 1.93
Increased sputum and bronchial biopsy IL-13 expression in severe asthma. J Allergy Clin Immunol (2008) 1.92
TH2 cytokine expression in bronchoalveolar lavage fluid T lymphocytes and bronchial submucosa is a feature of asthma and eosinophilic bronchitis. J Allergy Clin Immunol (2002) 1.92
Bronchial smooth muscle remodeling involves calcium-dependent enhanced mitochondrial biogenesis in asthma. J Exp Med (2007) 1.91
IgE sensitization to Aspergillus fumigatus is associated with reduced lung function in asthma. Am J Respir Crit Care Med (2010) 1.91
Macrophage and mast-cell invasion of tumor cell islets confers a marked survival advantage in non-small-cell lung cancer. J Clin Oncol (2005) 1.87
Airway hyperresponsiveness is dissociated from airway wall structural remodeling. J Allergy Clin Immunol (2008) 1.76
Sulfuryl fluoride as a quarantine treatment for Chlorophorus annularis (Coleoptera: Cerambycidae) in Chinese bamboo poles. J Econ Entomol (2010) 1.70
Comments on Point:Counterpoint: Alterations in airway smooth muscle phenotype do/do not cause airway hyperresponsiveness in asthma. J Appl Physiol (1985) (2012) 1.62
Airway smooth muscle and mast cell-derived CC chemokine ligand 19 mediate airway smooth muscle migration in asthma. Am J Respir Crit Care Med (2006) 1.53
Sputum and bronchial submucosal IL-13 expression in asthma and eosinophilic bronchitis. J Allergy Clin Immunol (2004) 1.52
Fraktalkine produced by airway smooth muscle cells contributes to mast cell recruitment in asthma. J Immunol (2006) 1.49
Calcium channel blocker reduces airway remodeling in severe asthma. A proof-of-concept study. Am J Respir Crit Care Med (2015) 1.48
Computed tomographic measurement of airway remodeling and emphysema in advanced chronic obstructive pulmonary disease. Correlation with pulmonary hypertension. Am J Respir Crit Care Med (2015) 1.47
Experimental Cerenkov luminescence tomography of the mouse model with SPECT imaging validation. Opt Express (2010) 1.45
Three-dimensional distribution of transient interactions in the nuclear pore complex obtained from single-molecule snapshots. Proc Natl Acad Sci U S A (2010) 1.45
C3a, mast cells, and asthma. FASEB J (2005) 1.42
Airway compliance studied by lumen area changes alone cannot discriminate between collapsibility and elasticity. Am J Respir Crit Care Med (2013) 1.39
Increased expression of immunoreactive thymic stromal lymphopoietin in patients with severe asthma. J Allergy Clin Immunol (2011) 1.38
Mast cells promote airway smooth muscle cell differentiation via autocrine up-regulation of TGF-beta 1. J Immunol (2008) 1.34
Bronchial measurements in patients with asthma: comparison of quantitative thin-section CT findings with those in healthy subjects and correlation with pathologic findings. Radiology (2009) 1.32
Self-regulated viscous channel in the nuclear pore complex. Proc Natl Acad Sci U S A (2012) 1.31
Cooperative molecular and cellular networks regulate Toll-like receptor-dependent inflammatory responses. FASEB J (2006) 1.30
Functional transient receptor potential melastatin 7 channels are critical for human mast cell survival. J Immunol (2007) 1.30
Assessment of airways with three-dimensional quantitative thin-section CT: in vitro and in vivo validation. Radiology (2006) 1.29
Clinical, radiologic, and induced sputum features of chronic obstructive pulmonary disease in nonsmokers: a descriptive study. Am J Respir Crit Care Med (2002) 1.27
Human airway smooth muscle promotes human lung mast cell survival, proliferation, and constitutive activation: cooperative roles for CADM1, stem cell factor, and IL-6. J Immunol (2008) 1.23
KCa3.1 Ca2+ activated K+ channels regulate human airway smooth muscle proliferation. Am J Respir Cell Mol Biol (2007) 1.20
Knowledge, attitude and practice of antibiotics: a questionnaire study among 2500 Chinese students. BMC Med Educ (2013) 1.20
Diminished allergic disease in patients with STAT3 mutations reveals a role for STAT3 signaling in mast cell degranulation. J Allergy Clin Immunol (2013) 1.19
Quantitative analysis of high-resolution computed tomography scans in severe asthma subphenotypes. Thorax (2010) 1.19
Single-molecule measurements of importin alpha/cargo complex dissociation at the nuclear pore. Proc Natl Acad Sci U S A (2008) 1.17
Vascular remodeling is a feature of asthma and nonasthmatic eosinophilic bronchitis. J Allergy Clin Immunol (2007) 1.17
Timed sequential therapy of acute leukemia with flavopiridol: in vitro model for a phase I clinical trial. Clin Cancer Res (2003) 1.17
Co-suppression of miR-221/222 cluster suppresses human glioma cell growth by targeting p27kip1 in vitro and in vivo. Int J Oncol (2009) 1.15
Differential expression of CCR3 and CXCR3 by human lung and bone marrow-derived mast cells: implications for tissue mast cell migration. J Leukoc Biol (2005) 1.14
The reclassification of asthma based on subphenotypes. Curr Opin Allergy Clin Immunol (2007) 1.14
β2-Agonist induced cAMP is decreased in asthmatic airway smooth muscle due to increased PDE4D. PLoS One (2011) 1.10
Activation of human mast cells through the platelet-activating factor receptor. J Allergy Clin Immunol (2010) 1.08
Perlecan domain I-conjugated, hyaluronic acid-based hydrogel particles for enhanced chondrogenic differentiation via BMP-2 release. Biomaterials (2009) 1.05
Inhibition of human mast cell proliferation and survival by tamoxifen in association with ion channel modulation. J Allergy Clin Immunol (2003) 1.05
Adenosine closes the K+ channel KCa3.1 in human lung mast cells and inhibits their migration via the adenosine A2A receptor. Eur J Immunol (2007) 1.04
Heme oxygenase inhibits human airway smooth muscle proliferation via a bilirubin-dependent modulation of ERK1/2 phosphorylation. J Biol Chem (2003) 1.04
The relationship between clinical outcomes and medication adherence in difficult-to-control asthma. Thorax (2012) 1.04
Airway remodeling in asthma: new mechanisms and potential for pharmacological intervention. Pharmacol Ther (2011) 1.03
Cuttine edge: diabetes-associated quantitative trait locus, Idd4, is responsible for the IL-12p40 overexpression defect in nonobese diabetic (NOD) mice. J Immunol (2003) 1.03
The tissue microlocalisation and cellular expression of CD163, VEGF, HLA-DR, iNOS, and MRP 8/14 is correlated to clinical outcome in NSCLC. PLoS One (2011) 1.01
Human lung mast cells adhere to human airway smooth muscle, in part, via tumor suppressor in lung cancer-1. J Immunol (2006) 1.00
Indiplon is a high-affinity positive allosteric modulator with selectivity for alpha1 subunit-containing GABAA receptors. J Pharmacol Exp Ther (2006) 0.99
Beta2-adrenoceptor regulation of the K+ channel iKCa1 in human mast cells. FASEB J (2005) 0.99
The pivotal role of airway smooth muscle in asthma pathophysiology. J Allergy (Cairo) (2011) 0.98
Three-dimensional noninvasive monitoring iodine-131 uptake in the thyroid using a modified Cerenkov luminescence tomography approach. PLoS One (2012) 0.97
Bronchial measurement with three-dimensional quantitative thin-section CT in patients with cystic fibrosis. Radiology (2006) 0.97
AMPK-regulated and Akt-dependent enhancement of glucose uptake is essential in ischemic preconditioning-alleviated reperfusion injury. PLoS One (2013) 0.97
Airway smooth muscle in asthma: just a target for bronchodilation? Clin Chest Med (2012) 0.96
CRACM/Orai ion channel expression and function in human lung mast cells. J Allergy Clin Immunol (2012) 0.96
Human lung mast cells mediate pneumococcal cell death in response to activation by pneumolysin. J Immunol (2010) 0.96
Intraspinal neurenteric cysts in children. Can J Neurol Sci (2008) 0.96
Coating electrospun collagen and gelatin fibers with perlecan domain I for increased growth factor binding. Biomacromolecules (2007) 0.95
Glucocorticoid receptor β and histone deacetylase 1 and 2 expression in the airways of severe asthma. Thorax (2011) 0.95
Chemokine receptor expression in tumour islets and stroma in non-small cell lung cancer. BMC Cancer (2010) 0.95
Functional KCa3.1 K+ channels are required for human fibrocyte migration. J Allergy Clin Immunol (2011) 0.95
IgE alone promotes human lung mast cell survival through the autocrine production of IL-6. BMC Immunol (2008) 0.94
Quantitative analysis of breast cancer resistance protein and cellular resistance to flavopiridol in acute leukemia patients. Clin Cancer Res (2003) 0.94
Proteolytic susceptibility of the serine protease inhibitor trappin-2 (pre-elafin): evidence for tryptase-mediated generation of elafin. Biol Chem (2005) 0.94
Single-molecule studies of nucleocytoplasmic transport: from one dimension to three dimensions. Integr Biol (Camb) (2011) 0.94
A proof-of-concept, randomized, controlled trial of omalizumab in patients with severe, difficult-to-control, nonatopic asthma. Chest (2013) 0.93
CCL11 and GM-CSF differentially use the Rho GTPase pathway to regulate motility of human eosinophils in a three-dimensional microenvironment. J Immunol (2008) 0.92
RNA interference decreases PAR-2 expression and function in human airway smooth muscle cells. Am J Respir Cell Mol Biol (2005) 0.91
Global changes of mRNA expression reveals an increased activity of the interferon-induced signal transducer and activator of transcription (STAT) pathway by repression of miR-221/222 in glioblastoma U251 cells. Int J Oncol (2010) 0.90
Airway remodeling in a mouse asthma model assessed by in-vivo respiratory-gated micro-computed tomography. Eur Radiol (2009) 0.90
Injectable perlecan domain 1-hyaluronan microgels potentiate the cartilage repair effect of BMP2 in a murine model of early osteoarthritis. Biomed Mater (2012) 0.89
A novel FcεRIβ-chain truncation regulates human mast cell proliferation and survival. FASEB J (2010) 0.89
Engagement of the EP2 prostanoid receptor closes the K+ channel KCa3.1 in human lung mast cells and attenuates their migration. Eur J Immunol (2008) 0.89
High-resolution three-dimensional mapping of mRNA export through the nuclear pore. Nat Commun (2013) 0.89