Published in Am J Respir Crit Care Med on December 03, 2004
Sepsis biomarkers: a review. Crit Care (2010) 4.76
Nampt/PBEF/Visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme. Cell Metab (2007) 4.16
Receptor for advanced glycation end-products is a marker of type I cell injury in acute lung injury. Am J Respir Crit Care Med (2006) 3.38
Adipose tissue: the new endocrine organ? A review article. Dig Dis Sci (2008) 2.26
Obesity and primary graft dysfunction after lung transplantation: the Lung Transplant Outcomes Group Obesity Study. Am J Respir Crit Care Med (2011) 2.11
Body mass index is associated with the development of acute respiratory distress syndrome. Thorax (2009) 1.96
Intracellular NAD levels regulate tumor necrosis factor protein synthesis in a sirtuin-dependent manner. Nat Med (2009) 1.70
Nicotinamide phosphoribosyltransferase (Nampt): a link between NAD biology, metabolism, and diseases. Curr Pharm Des (2009) 1.69
ANGPT2 genetic variant is associated with trauma-associated acute lung injury and altered plasma angiopoietin-2 isoform ratio. Am J Respir Crit Care Med (2011) 1.62
Microarray-based analysis of ventilator-induced lung injury. Proc Am Thorac Soc (2007) 1.58
Prognostic value of plasma N-terminal probrain natriuretic peptide levels in the acute respiratory distress syndrome. Crit Care Med (2008) 1.52
Pharmacological inhibition of nicotinamide phosphoribosyltransferase/visfatin enzymatic activity identifies a new inflammatory pathway linked to NAD. PLoS One (2008) 1.48
Pathogenetic significance of biological markers of ventilator-associated lung injury in experimental and clinical studies. Chest (2006) 1.45
Cigarette smoke-induced emphysema in A/J mice is associated with pulmonary oxidative stress, apoptosis of lung cells, and global alterations in gene expression. Am J Physiol Lung Cell Mol Physiol (2009) 1.40
Nicotinamide exacerbates hypoxemia in ventilator-induced lung injury independent of neutrophil infiltration. PLoS One (2015) 1.39
In vitro identification and in silico utilization of interspecies sequence similarities using GeneChip technology. BMC Genomics (2005) 1.39
Essential role of pre-B-cell colony enhancing factor in ventilator-induced lung injury. Am J Respir Crit Care Med (2008) 1.38
Recent advances in genetic predisposition to clinical acute lung injury. Am J Physiol Lung Cell Mol Physiol (2009) 1.34
Macrophage migration inhibitory factor in acute lung injury: expression, biomarker, and associations. Transl Res (2007) 1.21
Genetic variation in the FAS gene and associations with acute lung injury. Am J Respir Crit Care Med (2010) 1.19
Genome wide association identifies PPFIA1 as a candidate gene for acute lung injury risk following major trauma. PLoS One (2012) 1.11
Discovery of the gene signature for acute lung injury in patients with sepsis. Physiol Genomics (2009) 1.10
Integrating microRNAs into a system biology approach to acute lung injury. Transl Res (2011) 1.10
A quality assessment of genetic association studies supporting susceptibility and outcome in acute lung injury. Crit Care (2008) 1.08
GADD45a is a novel candidate gene in inflammatory lung injury via influences on Akt signaling. FASEB J (2009) 1.06
Poly(ADP-ribose) polymerase 1 at the crossroad of metabolic stress and inflammation in aging. Aging (Albany NY) (2009) 1.05
Inflammation and immune-related candidate gene associations with acute lung injury susceptibility and severity: a validation study. PLoS One (2012) 1.04
PSMB2 and RPL32 are suitable denominators to normalize gene expression profiles in bronchoalveolar cells. BMC Mol Biol (2008) 1.04
Neuronal protective role of PBEF in a mouse model of cerebral ischemia. J Cereb Blood Flow Metab (2010) 1.04
IL1RN coding variant is associated with lower risk of acute respiratory distress syndrome and increased plasma IL-1 receptor antagonist. Am J Respir Crit Care Med (2013) 1.03
Visfatin/Nampt: an adipokine with cardiovascular impact. Mediators Inflamm (2013) 1.03
Nicotinamide Phosphoribosyltransferase in Human Diseases. J Bioanal Biomed (2011) 1.01
Critical role of PBEF expression in pulmonary cell inflammation and permeability. Cell Biol Int (2008) 0.98
Type 2 deiodinase and host responses of sepsis and acute lung injury. Am J Respir Cell Mol Biol (2011) 0.94
Regulation of inflammatory cytokine expression in pulmonary epithelial cells by pre-B-cell colony-enhancing factor via a nonenzymatic and AP-1-dependent mechanism. J Biol Chem (2009) 0.92
Visfatin in human pregnancy: maternal gestational diabetes vis-à-vis neonatal birthweight. J Perinat Med (2009) 0.92
Genetic epidemiology of acute respiratory distress syndrome: implications for future prevention and treatment. Clin Chest Med (2006) 0.90
Pre-B cell colony enhancing factor (PBEF), a cytokine with multiple physiological functions. Cytokine Growth Factor Rev (2013) 0.90
Making genomics functional: deciphering the genetics of acute lung injury. Proc Am Thorac Soc (2008) 0.90
Mechanical stress induces pre-B-cell colony-enhancing factor/NAMPT expression via epigenetic regulation by miR-374a and miR-568 in human lung endothelium. Am J Respir Cell Mol Biol (2014) 0.90
Integrative assessment of chlorine-induced acute lung injury in mice. Am J Respir Cell Mol Biol (2012) 0.89
Genetic determinants and ethnic disparities in sepsis-associated acute lung injury. Proc Am Thorac Soc (2005) 0.89
Nicotinamide phosphoribosyltransferase inhibitor is a novel therapeutic candidate in murine models of inflammatory lung injury. Am J Respir Cell Mol Biol (2014) 0.88
Genetic polymorphisms associated with acute lung injury. Pharmacogenomics (2009) 0.88
Reciprocal congenic lines of mice capture the aliq1 effect on acute lung injury survival time. Am J Respir Cell Mol Biol (2007) 0.88
Adipokines NUCB2/nesfatin-1 and visfatin as novel inflammatory factors in chronic obstructive pulmonary disease. Mediators Inflamm (2014) 0.87
Bioinformatics insights into acute lung injury/acute respiratory distress syndrome. Clin Transl Med (2012) 0.87
Role of adipokines signaling in the modulation of T cells function. Front Immunol (2013) 0.87
Visfatin, glucose metabolism and vascular disease: a review of evidence. Diabetol Metab Syndr (2010) 0.87
Proinflammatory actions of visfatin/nicotinamide phosphoribosyltransferase (Nampt) involve regulation of insulin signaling pathway and Nampt enzymatic activity. J Biol Chem (2012) 0.86
Maternal visfatin concentration in normal pregnancy. J Perinat Med (2009) 0.86
Unique Toll-Like Receptor 4 Activation by NAMPT/PBEF Induces NFκB Signaling and Inflammatory Lung Injury. Sci Rep (2015) 0.85
Role of growth arrest and DNA damage-inducible α in Akt phosphorylation and ubiquitination after mechanical stress-induced vascular injury. Am J Respir Crit Care Med (2011) 0.85
Visfatin levels and intima-media thicknesses in rheumatic diseases. Clin Rheumatol (2010) 0.85
Interactions between PBEF and oxidative stress proteins--a potential new mechanism underlying PBEF in the pathogenesis of acute lung injury. FEBS Lett (2008) 0.84
Augmentation of Pulmonary Epithelial Cell IL-8 Expression and Permeability by Pre-B-cell Colony Enhancing Factor. J Inflamm (Lond) (2008) 0.84
Searching for candidate genes in acute lung injury: SNPs, Chips and PBEF. Trans Am Clin Climatol Assoc (2005) 0.84
Functional promoter variants in sphingosine 1-phosphate receptor 3 associate with susceptibility to sepsis-associated acute respiratory distress syndrome. Am J Physiol Lung Cell Mol Physiol (2013) 0.84
Loss-of-function thrombospondin-1 mutations in familial pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol (2011) 0.83
Stretch and inflammation-induced Pre-B cell colony-enhancing factor (PBEF/Visfatin) and Interleukin-8 in amniotic epithelial cells. Placenta (2010) 0.82
The NAMPT promoter is regulated by mechanical stress, signal transducer and activator of transcription 5, and acute respiratory distress syndrome-associated genetic variants. Am J Respir Cell Mol Biol (2014) 0.82
Integrating genomic and clinical medicine: searching for susceptibility genes in complex lung diseases. Transl Res (2007) 0.82
Expression of nicotinamide phosphoribosyltransferase-influenced genes predicts recurrence-free survival in lung and breast cancers. Sci Rep (2014) 0.82
Searching for acute respiratory distress syndrome genes: aren't we there yet? Am J Respir Crit Care Med (2005) 0.82
GADD45a promoter regulation by a functional genetic variant associated with acute lung injury. PLoS One (2014) 0.81
Plasma and myocardial visfatin expression changes are associated with therapeutic hypothermia protection during murine hemorrhagic shock/resuscitation. Resuscitation (2010) 0.81
Visfatin as a novel mediator released by inflamed human endothelial cells. PLoS One (2013) 0.80
Prognostic significance of elevated cardiac troponin-T levels in acute respiratory distress syndrome patients. PLoS One (2012) 0.79
Focusing on the flood: targeting functional polymorphisms in ALI permeability pathways. Am J Respir Crit Care Med (2011) 0.79
A critical role of nicotinamide phosphoribosyltransferase in human telomerase reverse transcriptase induction by resveratrol in aortic smooth muscle cells. Oncotarget (2015) 0.79
Bacterial translocation - impact on the adipocyte compartment. Front Immunol (2014) 0.78
Pre-B-cell colony-enhancing factor and its clinical correlates with acute lung injury and sepsis. Chest (2011) 0.78
Genomic investigations into acute inflammatory lung injury. Proc Am Thorac Soc (2011) 0.78
Serum adipokine concentrations in dogs with acute pancreatitis. J Vet Intern Med (2014) 0.78
Microarray meta-analysis identifies acute lung injury biomarkers in donor lungs that predict development of primary graft failure in recipients. PLoS One (2012) 0.78
The potential interplay of adipokines with toll-like receptors in the development of hepatocellular carcinoma. Gastroenterol Res Pract (2011) 0.78
Interlinking Periodontitis and Type 2 Diabetes Mellitus by Assessment of Crevicular Visfatin Levels in Health and in Disease Before and After Initial Periodontal Therapy. J Clin Diagn Res (2016) 0.77
Identification of novel single nucleotide polymorphisms associated with acute respiratory distress syndrome by exome-seq. PLoS One (2014) 0.77
The Role of Nicotinamide Phosphoribosyltransferase in Cerebral Ischemia. Curr Top Med Chem (2015) 0.76
Association of Nicotinamide Phosphoribosyltransferase (NAMPT) Gene Polymorphisms and of Serum NAMPT Levels with Dilated Cardiomyopathy in a Chinese Population. Int J Mol Sci (2015) 0.76
Maternal plasma concentration of the pro-inflammatory adipokine pre-B-cell-enhancing factor (PBEF)/visfatin is elevated in pregnant patients with acute pyelonephritis. Am J Reprod Immunol (2010) 0.76
Genetic variant in visfatin gene promoter contributes to reduced risk of hepatocellular carcinoma in a Chinese population. Oncotarget (2016) 0.75
In-vitro function of upstream visfatin polymorphisms that are associated with adverse cardiometabolic parameters in obese children. BMC Genomics (2016) 0.75
Endothelial Cell Signaling and Ventilator-Induced Lung Injury (VILI): Molecular Mechanisms, Genomic Analyses & Therapeutic Targets. Am J Physiol Lung Cell Mol Physiol (2016) 0.75
Nampt/PBEF/visfatin serum levels: a new biomarker for retinal blood vessel occlusions. Clin Ophthalmol (2015) 0.75
Metabolic and molecular insights into an essential role of nicotinamide phosphoribosyltransferase. Cell Death Dis (2017) 0.75
Endotoxin- and mechanical stress-induced epigenetic changes in the regulation of the nicotinamide phosphoribosyltransferase promoter. Pulm Circ (2016) 0.75
Targeting of nicotinamide phosphoribosyltransferase enzymatic activity ameliorates lung damage induced by ischemia/reperfusion in rats. Respir Res (2017) 0.75
MC-PPEA as a new and more potent inhibitor of CLP-induced sepsis and pulmonary inflammation than FK866. Drug Des Devel Ther (2017) 0.75
Serum Concentrations of Leptin and Adiponectin in Dogs with Myxomatous Mitral Valve Disease. J Vet Intern Med (2016) 0.75
Effect of Non-surgical Periodontal Therapy on Serum and Salivary Concentrations of Visfatin in Patients with Chronic Periodontitis. J Dent Res Dent Clin Dent Prospects (2015) 0.75
ANLN truncation causes a familial fatal acute respiratory distress syndrome in Dalmatian dogs. PLoS Genet (2017) 0.75
Peptidomic analysis of human peripheral monocytes persistently infected by Chlamydia trachomatis. Med Microbiol Immunol (2007) 0.75
Beyond single-nucleotide polymorphisms: genetics, genomics, and other 'omic approaches to acute respiratory distress syndrome. Clin Chest Med (2014) 0.75
Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med (2000) 48.03
Development of human protein reference database as an initial platform for approaching systems biology in humans. Genome Res (2003) 14.79
Multiple-laboratory comparison of microarray platforms. Nat Methods (2005) 11.74
The genetic association database. Nat Genet (2004) 11.29
Sensitive detection of chromosomal segments of distinct ancestry in admixed populations. PLoS Genet (2009) 6.36
Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice. J Clin Invest (2004) 6.32
Driving pressure and survival in the acute respiratory distress syndrome. N Engl J Med (2015) 6.06
Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1. Blood (2004) 5.71
Optimal unified approach for rare-variant association testing with application to small-sample case-control whole-exome sequencing studies. Am J Hum Genet (2012) 5.48
Randomized, placebo-controlled clinical trial of an aerosolized β₂-agonist for treatment of acute lung injury. Am J Respir Crit Care Med (2011) 5.24
Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice. J Exp Med (2005) 4.31
Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice. Nat Med (2005) 4.31
Variants of DENND1B associated with asthma in children. N Engl J Med (2009) 4.18
Retracted Expression of concern: Decline in NRF2-regulated antioxidants in chronic obstructive pulmonary disease lungs due to loss of its positive regulator, DJ-1. Am J Respir Crit Care Med (2008) 3.93
Short telomeres are a risk factor for idiopathic pulmonary fibrosis. Proc Natl Acad Sci U S A (2008) 3.86
Tidal volume reduction in patients with acute lung injury when plateau pressures are not high. Am J Respir Crit Care Med (2005) 3.69
Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. Nat Genet (2011) 3.68
Detectable clonal mosaicism from birth to old age and its relationship to cancer. Nat Genet (2012) 3.68
Protective effects of sphingosine 1-phosphate in murine endotoxin-induced inflammatory lung injury. Am J Respir Crit Care Med (2004) 3.59
Activated protein C mediates novel lung endothelial barrier enhancement: role of sphingosine 1-phosphate receptor transactivation. J Biol Chem (2005) 3.54
The Gene, Environment Association Studies consortium (GENEVA): maximizing the knowledge obtained from GWAS by collaboration across studies of multiple conditions. Genet Epidemiol (2010) 3.48
Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene. Am J Hum Genet (2009) 3.41
Rosuvastatin for sepsis-associated acute respiratory distress syndrome. N Engl J Med (2014) 3.39
Telomere length is a determinant of emphysema susceptibility. Am J Respir Crit Care Med (2011) 3.28
Genetics and epidemiology. Curr Opin Allergy Clin Immunol (2002) 3.12
Pathobiology of cigarette smoke-induced chronic obstructive pulmonary disease. Physiol Rev (2007) 3.03
Expression of human herpesvirus 8 in primary pulmonary hypertension. N Engl J Med (2003) 3.00
CD4+CD25+Foxp3+ Tregs resolve experimental lung injury in mice and are present in humans with acute lung injury. J Clin Invest (2009) 2.96
Incidence of acute lung injury in the United States. Crit Care Med (2003) 2.93
Role of PD-1 and its ligand, B7-H1, in early fate decisions of CD8 T cells. Blood (2007) 2.93
Magnitude-dependent regulation of pulmonary endothelial cell barrier function by cyclic stretch. Am J Physiol Lung Cell Mol Physiol (2003) 2.89
Reducing deep sedation and delirium in acute lung injury patients: a quality improvement project. Crit Care Med (2013) 2.89
Endothelial dysfunction in pulmonary hypertension. Circulation (2004) 2.82
Cytokine modulation of atopic dermatitis filaggrin skin expression. J Allergy Clin Immunol (2007) 2.79
Sphingosine 1-phosphate reduces vascular leak in murine and canine models of acute lung injury. Am J Respir Crit Care Med (2004) 2.73
Lung protective mechanical ventilation and two year survival in patients with acute lung injury: prospective cohort study. BMJ (2012) 2.69
Modern age pathology of pulmonary arterial hypertension. Am J Respir Crit Care Med (2012) 2.68
Low caloric intake is associated with nosocomial bloodstream infections in patients in the medical intensive care unit. Crit Care Med (2004) 2.65
Toll-like receptor 1 polymorphisms affect innate immune responses and outcomes in sepsis. Am J Respir Crit Care Med (2008) 2.64
Effects of recruitment maneuvers in patients with acute lung injury and acute respiratory distress syndrome ventilated with high positive end-expiratory pressure. Crit Care Med (2003) 2.63
Early physical medicine and rehabilitation for patients with acute respiratory failure: a quality improvement project. Arch Phys Med Rehabil (2010) 2.61
State of the Art. A structural and functional assessment of the lung via multidetector-row computed tomography: phenotyping chronic obstructive pulmonary disease. Proc Am Thorac Soc (2006) 2.60
A combinatorial F box protein directed pathway controls TRAF adaptor stability to regulate inflammation. Nat Immunol (2013) 2.60
A genome-wide association study on African-ancestry populations for asthma. J Allergy Clin Immunol (2009) 2.53
Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice. Proc Natl Acad Sci U S A (2008) 2.53
Ischemic acute kidney injury induces a distant organ functional and genomic response distinguishable from bilateral nephrectomy. Am J Physiol Renal Physiol (2007) 2.46
Pulmonary endothelial cell barrier enhancement by sphingosine 1-phosphate: roles for cortactin and myosin light chain kinase. J Biol Chem (2004) 2.44
Alterations of cellular bioenergetics in pulmonary artery endothelial cells. Proc Natl Acad Sci U S A (2007) 2.44
Prioritizing the organization and management of intensive care services in the United States: the PrOMIS Conference. Crit Care Med (2007) 2.42
An animal model of autoimmune emphysema. Am J Respir Crit Care Med (2004) 2.40
A protocol for high-frequency oscillatory ventilation in adults: results from a roundtable discussion. Crit Care Med (2007) 2.38
Airway pressures, tidal volumes, and mortality in patients with acute respiratory distress syndrome. Crit Care Med (2005) 2.37
Regulation of sphingosine 1-phosphate-induced endothelial cytoskeletal rearrangement and barrier enhancement by S1P1 receptor, PI3 kinase, Tiam1/Rac1, and alpha-actinin. FASEB J (2005) 2.29
Mitochondrial metabolism, redox signaling, and fusion: a mitochondria-ROS-HIF-1alpha-Kv1.5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer. Am J Physiol Heart Circ Physiol (2007) 2.26
Differential regulation of pulmonary endothelial monolayer integrity by varying degrees of cyclic stretch. Am J Pathol (2006) 2.25
Relationship between dynamic respiratory mechanics and disease heterogeneity in sheep lavage injury. Crit Care Med (2007) 2.25
Vascular endothelial growth factor in the lung. Am J Physiol Lung Cell Mol Physiol (2006) 2.25
Association between the MUC5B promoter polymorphism and survival in patients with idiopathic pulmonary fibrosis. JAMA (2013) 2.20
Filaggrin mutations that confer risk of atopic dermatitis confer greater risk for eczema herpeticum. J Allergy Clin Immunol (2009) 2.20
Hyperoxia-induced NAD(P)H oxidase activation and regulation by MAP kinases in human lung endothelial cells. Am J Physiol Lung Cell Mol Physiol (2002) 2.18
Prognostic and pathogenetic value of combining clinical and biochemical indices in patients with acute lung injury. Chest (2009) 2.17
Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis. Nat Genet (2012) 2.14
Simvastatin attenuates vascular leak and inflammation in murine inflammatory lung injury. Am J Physiol Lung Cell Mol Physiol (2005) 2.13
Idiopathic pulmonary fibrosis and pulmonary hypertension: connecting the dots. Am J Respir Crit Care Med (2007) 2.11
Nasopharyngeal carcinoma treated by radical radiotherapy alone: Ten-year experience of a single institution. Int J Radiat Oncol Biol Phys (2006) 2.11
Gain-of-function mutation of GATA-2 in acute myeloid transformation of chronic myeloid leukemia. Proc Natl Acad Sci U S A (2008) 2.10
Blood pressure excursions below the cerebral autoregulation threshold during cardiac surgery are associated with acute kidney injury. Crit Care Med (2013) 2.09
Somatic chromosome abnormalities in the lungs of patients with pulmonary arterial hypertension. Am J Respir Crit Care Med (2010) 2.09
The local and systemic inflammatory transcriptome after acute kidney injury. J Am Soc Nephrol (2008) 2.08
Characterization of the interstitial lung diseases via density-based and texture-based analysis of computed tomography images of lung structure and function. Acad Radiol (2003) 2.08
Role of Rho GTPases in thrombin-induced lung vascular endothelial cells barrier dysfunction. Microvasc Res (2004) 2.07
Predicting the limits of cerebral autoregulation during cardiopulmonary bypass. Anesth Analg (2011) 2.07
Caloric intake in medical ICU patients: consistency of care with guidelines and relationship to clinical outcomes. Chest (2003) 2.05
Variant IRAK-1 haplotype is associated with increased nuclear factor-kappaB activation and worse outcomes in sepsis. Am J Respir Crit Care Med (2006) 2.05
Ethnic differences and functional analysis of MET mutations in lung cancer. Clin Cancer Res (2009) 2.03
Real-time continuous monitoring of cerebral blood flow autoregulation using near-infrared spectroscopy in patients undergoing cardiopulmonary bypass. Stroke (2010) 2.02
In vitro and in vivo modulation of vascular barrier integrity by sphingosine 1-phosphate: mechanistic insights. Cell Signal (2005) 2.01
Fluid balance, diuretic use, and mortality in acute kidney injury. Clin J Am Soc Nephrol (2011) 2.00
Phenotype of atopic dermatitis subjects with a history of eczema herpeticum. J Allergy Clin Immunol (2009) 2.00
The effect of a quality improvement intervention on perceived sleep quality and cognition in a medical ICU. Crit Care Med (2013) 2.00
Novel role of microtubules in thrombin-induced endothelial barrier dysfunction. FASEB J (2004) 1.98
The role of the microtubules in tumor necrosis factor-alpha-induced endothelial cell permeability. Am J Respir Cell Mol Biol (2003) 1.93
Recruitment maneuvers for acute lung injury: a systematic review. Am J Respir Crit Care Med (2008) 1.91
Circulating angiogenic precursors in idiopathic pulmonary arterial hypertension. Am J Pathol (2008) 1.90
Epoxycyclopentenone-containing oxidized phospholipids restore endothelial barrier function via Cdc42 and Rac. Circ Res (2004) 1.88
Novel polymorphisms in the myosin light chain kinase gene confer risk for acute lung injury. Am J Respir Cell Mol Biol (2006) 1.88