Published in FEBS J on February 01, 2005
Recent Advances in Synthetic Membrane Transporters. Supramol Chem (2007) 0.91
Kinetics of peptide folding in lipid membranes. Biopolymers (2015) 0.77
Recognition dynamics up to microseconds revealed from an RDC-derived ubiquitin ensemble in solution. Science (2008) 8.04
Release of long-range tertiary interactions potentiates aggregation of natively unstructured alpha-synuclein. Proc Natl Acad Sci U S A (2005) 3.48
Structure of the human voltage-dependent anion channel. Proc Natl Acad Sci U S A (2008) 2.69
Pre-fibrillar alpha-synuclein variants with impaired beta-structure increase neurotoxicity in Parkinson's disease models. EMBO J (2009) 2.09
Atomic model of the type III secretion system needle. Nature (2012) 2.02
Defining long-range order and local disorder in native alpha-synuclein using residual dipolar couplings. J Am Chem Soc (2005) 1.75
Model-free analysis of protein backbone motion from residual dipolar couplings. J Am Chem Soc (2002) 1.65
A ligand-induced switch in the periplasmic domain of sensor histidine kinase CitA. J Mol Biol (2008) 1.61
Structural polymorphism of 441-residue tau at single residue resolution. PLoS Biol (2009) 1.61
Sites of tau important for aggregation populate {beta}-structure and bind to microtubules and polyanions. J Biol Chem (2005) 1.54
Structural characterization of copper(II) binding to alpha-synuclein: Insights into the bioinorganic chemistry of Parkinson's disease. Proc Natl Acad Sci U S A (2005) 1.50
Highly populated turn conformations in natively unfolded tau protein identified from residual dipolar couplings and molecular simulation. J Am Chem Soc (2007) 1.49
The NMR structure of the sensory domain of the membranous two-component fumarate sensor (histidine protein kinase) DcuS of Escherichia coli. J Biol Chem (2003) 1.48
Weak long-range correlated motions in a surface patch of ubiquitin involved in molecular recognition. J Am Chem Soc (2011) 1.45
NMR of alpha-synuclein-polyamine complexes elucidates the mechanism and kinetics of induced aggregation. EMBO J (2004) 1.41
Protein conformational flexibility from structure-free analysis of NMR dipolar couplings: quantitative and absolute determination of backbone motion in ubiquitin. Angew Chem Int Ed Engl (2009) 1.38
Protein refolding is required for assembly of the type three secretion needle. Nat Struct Mol Biol (2010) 1.36
A thorough dynamic interpretation of residual dipolar couplings in ubiquitin. J Biomol NMR (2006) 1.34
Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease. Acta Neuropathol (2013) 1.34
Self-consistent residual dipolar coupling based model-free analysis for the robust determination of nanosecond to microsecond protein dynamics. J Biomol NMR (2008) 1.33
Quantitative determination of the conformational properties of partially folded and intrinsically disordered proteins using NMR dipolar couplings. Structure (2009) 1.33
Familial mutants of alpha-synuclein with increased neurotoxicity have a destabilized conformation. J Biol Chem (2005) 1.30
Interaction of alpha-synuclein with divalent metal ions reveals key differences: a link between structure, binding specificity and fibrillation enhancement. J Am Chem Soc (2006) 1.28
A correspondence between solution-state dynamics of an individual protein and the sequence and conformational diversity of its family. PLoS Comput Biol (2009) 1.27
The "jaws" of the tau-microtubule interaction. J Biol Chem (2007) 1.25
Novel techniques for weak alignment of proteins in solution using chemical tags coordinating lanthanide ions. J Biomol NMR (2004) 1.22
Structural characterization of the intrinsically unfolded protein beta-synuclein, a natural negative regulator of alpha-synuclein aggregation. J Mol Biol (2007) 1.21
Inhibition of the D-alanine:D-alanyl carrier protein ligase from Bacillus subtilis increases the bacterium's susceptibility to antibiotics that target the cell wall. FEBS J (2005) 1.21
Plasticity of the PAS domain and a potential role for signal transduction in the histidine kinase DcuS. Nat Struct Mol Biol (2008) 1.17
Similarity of SABRE field dependence in chemically different substrates. J Magn Reson (2011) 1.17
Structure of the NCoA-1/SRC-1 PAS-B domain bound to the LXXLL motif of the STAT6 transactivation domain. J Mol Biol (2004) 1.16
Characterization of Alzheimer's-like paired helical filaments from the core domain of tau protein using solid-state NMR spectroscopy. J Am Chem Soc (2008) 1.15
Site-specific interactions of Cu(II) with alpha and beta-synuclein: bridging the molecular gap between metal binding and aggregation. J Am Chem Soc (2008) 1.15
Structural basis of the activity of the microtubule-stabilizing agent epothilone a studied by NMR spectroscopy in solution. Angew Chem Int Ed Engl (2007) 1.13
Functional dynamics in the voltage-dependent anion channel. Proc Natl Acad Sci U S A (2010) 1.13
Conformational changes specific for pseudophosphorylation at serine 262 selectively impair binding of tau to microtubules. Biochemistry (2009) 1.12
A glutathione-dependent formaldehyde-activating enzyme (Gfa) from Paracoccus denitrificans detected and purified via two-dimensional proton exchange NMR spectroscopy. J Biol Chem (2001) 1.11
Bilayer in small bicelles revealed by lipid-protein interactions using NMR spectroscopy. J Am Chem Soc (2008) 1.11
The high-resolution solution structure of epothilone A bound to tubulin: an understanding of the structure-activity relationships for a powerful class of antitumor agents. Angew Chem Int Ed Engl (2003) 1.09
Side-chain orientation and hydrogen-bonding imprint supra-Tau(c) motion on the protein backbone of ubiquitin. Angew Chem Int Ed Engl (2005) 1.09
Modular architecture of Munc13/calmodulin complexes: dual regulation by Ca2+ and possible function in short-term synaptic plasticity. EMBO J (2009) 1.09
Kinetics of conformational sampling in ubiquitin. Angew Chem Int Ed Engl (2011) 1.07
Apoptolidin: induction of apoptosis by a natural product. Angew Chem Int Ed Engl (2006) 1.07
The native conformation of the human VDAC1 N terminus. Angew Chem Int Ed Engl (2010) 1.05
The INPHARMA method: protein-mediated interligand NOEs for pharmacophore mapping. Angew Chem Int Ed Engl (2005) 1.04
β-Barrel mobility underlies closure of the voltage-dependent anion channel. Structure (2012) 1.04
β-Sheet core of tau paired helical filaments revealed by solid-state NMR. J Am Chem Soc (2012) 1.03
Antimalarial drug quinacrine binds to C-terminal helix of cellular prion protein. J Med Chem (2003) 1.03
Total synthesis of apoptolidin. Angew Chem Int Ed Engl (2004) 1.02
Self-consistency analysis of dipolar couplings in multiple alignments of ubiquitin. J Am Chem Soc (2003) 1.01
Field dependent dynamic nuclear polarization with radicals in aqueous solution. J Am Chem Soc (2008) 1.01
The nature of the stimulus and of the fumarate binding site of the fumarate sensor DcuS of Escherichia coli. J Biol Chem (2005) 1.00
Structural characterization of Ca(2+)-ATPase-bound phospholamban in lipid bilayers by solid-state nuclear magnetic resonance (NMR) spectroscopy. Biochemistry (2008) 1.00
Structural and mechanistic basis behind the inhibitory interaction of PcTS on alpha-synuclein amyloid fibril formation. Proc Natl Acad Sci U S A (2009) 0.99
Apoptolidinone A: synthesis of the apoptolidin A aglycone. Chemistry (2006) 0.99
Paramagnetic tagging of diamagnetic proteins for solution NMR. Magn Reson Chem (2006) 0.98
Apoptolidin A: total synthesis and partially glycosylated analogues. Chemistry (2006) 0.97
Indirect DNA readout by an H-NS related protein: structure of the DNA complex of the C-terminal domain of Ler. PLoS Pathog (2011) 0.97
Electrophysiological response of cultured trabecular meshwork cells to synthetic ion channels. Chem Biol (2003) 0.97
Prion protein helix1 promotes aggregation but is not converted into beta-sheet. J Biol Chem (2006) 0.96
A structural model of the complex formed by phospholamban and the calcium pump of sarcoplasmic reticulum obtained by molecular mechanics. Chembiochem (2002) 0.96
Mobility of a one-dimensional confined file of water molecules as a function of file length. Phys Rev Lett (2006) 0.95
Orientational and dynamical heterogeneity of rhodamine 6G terminally attached to a DNA helix revealed by NMR and single-molecule fluorescence spectroscopy. J Am Chem Soc (2007) 0.95
Shuttle DNP spectrometer with a two-center magnet. Phys Chem Chem Phys (2010) 0.95
(1)H and (13)C dynamic nuclear polarization in aqueous solution with a two-field (0.35 T/14 T) shuttle DNP spectrometer. J Am Chem Soc (2009) 0.94
Structural insights into the calmodulin-Munc13 interaction obtained by cross-linking and mass spectrometry. Biochemistry (2009) 0.94
Derivation of dihedral angles from CH-CH dipolar-dipolar cross-correlated relaxation rates: a C-C torsion involving a quaternary carbon atom in epothilone A bound to tubulin. Angew Chem Int Ed Engl (2003) 0.93
A designed conformational shift to control protein binding specificity. Angew Chem Int Ed Engl (2014) 0.93
The dynamic structure of filamentous tau. Angew Chem Int Ed Engl (2011) 0.92
Stereoselective synthesis of methyl 7-dihydro-trioxacarcinoside B. Org Lett (2007) 0.91
Two new chiral EDTA-based metal chelates for weak alignment of proteins in solution. Org Lett (2006) 0.91
Population shuffling of protein conformations. Angew Chem Int Ed Engl (2014) 0.91
Toward a predictive understanding of slow methyl group dynamics in proteins. Biophys J (2011) 0.91
Accessing ns-micros side chain dynamics in ubiquitin with methyl RDCs. J Biomol NMR (2009) 0.91
Residual dipolar couplings as a tool to study molecular recognition of ubiquitin. Biochem Soc Trans (2008) 0.90
2-Aminopurine incorporation perturbs the dynamics and structure of DNA. Angew Chem Int Ed Engl (2010) 0.90
Dipolar couplings in multiple alignments suggest alpha helical motion in ubiquitin. J Am Chem Soc (2003) 0.90
Sensing by the membrane-bound sensor kinase DcuS: exogenous versus endogenous sensing of C(4)-dicarboxylates in bacteria. Future Microbiol (2010) 0.89
Bioinorganic chemistry of Parkinson's disease: structural determinants for the copper-mediated amyloid formation of alpha-synuclein. Inorg Chem (2010) 0.89
RDC-enhanced NMR spectroscopy in structure elucidation of sucro-neolambertellin. Angew Chem Int Ed Engl (2008) 0.88
Structural and microtubule binding properties of tau mutants of frontotemporal dementias. Biochemistry (2007) 0.88
Stable expression of soluble therapeutic peptides in eukaryotic cells by multimerisation: application to the HIV-1 fusion inhibitory peptide C46. ChemMedChem (2006) 0.88
Interaction of epothilone B (patupilone) with microtubules as detected by two-dimensional solid-state NMR spectroscopy. Angew Chem Int Ed Engl (2010) 0.88
Exceeding the limit of dynamics studies on biomolecules using high spin-lock field strengths with a cryogenically cooled probehead. J Magn Reson (2012) 0.87
Structure and dynamics of triazole-linked DNA: biocompatibility explained. Chemistry (2011) 0.87
The cofactor of the iron-sulfur cluster free hydrogenase hmd: structure of the light-inactivation product. Angew Chem Int Ed Engl (2004) 0.87
P160/SRC/NCoA coactivators form complexes via specific interaction of their PAS-B domain with the CID/AD1 domain. Nucleic Acids Res (2008) 0.87
The INPHARMA technique for pharmacophore mapping: A theoretical guide to the method. J Magn Reson (2009) 0.87
Convenient synthesis of multifunctional EDTA-based chiral metal chelates substituted with an S-mesylcysteine. Chemistry (2005) 0.87
Correlating calcium binding, Förster resonance energy transfer, and conformational change in the biosensor TN-XXL. Biophys J (2012) 0.87
Total synthesis of phoslactomycin A. Org Lett (2009) 0.86
Synthesis of Apoptolidinone This work was supported by the Fonds der Chemischen Industrie, Schering AG, and the Schering Forschungsgesellschaft. We thank Prof. Dr. U. Eder (Schering AG, Berlin) for stimulating and helpful discussions. Angew Chem Int Ed Engl (2001) 0.86
Crown ether-gramicidin hybrid ion channels: dehydration-assisted ion selectivity. Angew Chem Int Ed Engl (2006) 0.86
Interdomain dynamics explored by paramagnetic NMR. J Am Chem Soc (2013) 0.86
Structural studies on a twin-arginine signal sequence. FEBS Lett (2003) 0.86
NMR spectroscopic determination of the solution structure of a branched nucleic acid from residual dipolar couplings by using isotopically labeled nucleotides. Angew Chem Int Ed Engl (2004) 0.85
A dynamic zinc redox switch. J Biol Chem (2004) 0.85
Nucleotide interactions of the human voltage-dependent anion channel. J Biol Chem (2014) 0.85
NMR solution structure and dynamics of the peptidyl-prolyl cis-trans isomerase domain of the trigger factor from Mycoplasma genitalium compared to FK506-binding protein. J Mol Biol (2002) 0.84