Published in Diabetes on April 01, 2005
The number of x chromosomes causes sex differences in adiposity in mice. PLoS Genet (2012) 2.02
Sex and depot differences in adipocyte insulin sensitivity and glucose metabolism. Diabetes (2009) 1.76
Estrogen and androgen receptors: regulators of fuel homeostasis and emerging targets for diabetes and obesity. Trends Endocrinol Metab (2010) 1.41
FOXO1 transrepresses peroxisome proliferator-activated receptor gamma transactivation, coordinating an insulin-induced feed-forward response in adipocytes. J Biol Chem (2009) 1.29
Atrazine-induced aromatase expression is SF-1 dependent: implications for endocrine disruption in wildlife and reproductive cancers in humans. Environ Health Perspect (2007) 1.27
Mice with a deletion in the gene for CCAAT/enhancer-binding protein beta are protected against diet-induced obesity. Diabetes (2007) 1.20
Sex differences in the physiology of eating. Am J Physiol Regul Integr Comp Physiol (2013) 1.18
Effects of age and dysfunction on human meibomian glands. Arch Ophthalmol (2011) 1.11
Adiponectin activates adenosine monophosphate-activated protein kinase and decreases luteinizing hormone secretion in LbetaT2 gonadotropes. Mol Endocrinol (2007) 1.08
Sex-specific differences in lipid and glucose metabolism. Front Endocrinol (Lausanne) (2015) 1.08
Differential effects of estrogen/androgen on the prevention of nonalcoholic fatty liver disease in the male rat. J Lipid Res (2012) 1.00
Estradiol treatment, physical activity, and muscle function in ovarian-senescent mice. Exp Gerontol (2011) 0.97
The pituitary function of androgen receptor constitutes a glucocorticoid production circuit. Mol Cell Biol (2007) 0.97
Deletion of the androgen receptor in adipose tissue in male mice elevates retinol binding protein 4 and reveals independent effects on visceral fat mass and on glucose homeostasis. Diabetes (2012) 0.95
Myocyte androgen receptors increase metabolic rate and improve body composition by reducing fat mass. Endocrinology (2010) 0.94
Lowered testosterone in male obesity: mechanisms, morbidity and management. Asian J Androl (2014) 0.91
The role of androgens in metabolism, obesity, and diabetes in males and females. Obesity (Silver Spring) (2015) 0.90
Androgens and adipose tissue in males: a complex and reciprocal interplay. Int J Endocrinol (2011) 0.89
Body composition changes and inhibition of fat development in vivo implicates androgen in regulation of stem cell lineage allocation. J Cell Biochem (2011) 0.89
Androgen receptor (AR) pathophysiological roles in androgen-related diseases in skin, bone/muscle, metabolic syndrome and neuron/immune systems: lessons learned from mice lacking AR in specific cells. Nucl Recept Signal (2013) 0.88
Associations of sex hormone-binding globulin and testosterone with diabetes among men and women (the Saku Diabetes study): a case control study. Cardiovasc Diabetol (2012) 0.88
Developmental androgen excess disrupts reproduction and energy homeostasis in adult male mice. J Endocrinol (2013) 0.86
Androgen receptor promotes sex-independent angiogenesis in response to ischemia and is required for activation of vascular endothelial growth factor receptor signaling. Circulation (2013) 0.84
Human androgen deficiency: insights gained from androgen receptor knockout mouse models. Asian J Androl (2014) 0.84
Impairment of vesicular ATP release affects glucose metabolism and increases insulin sensitivity. Sci Rep (2014) 0.84
Bofutsushosan, a Japanese herbal (Kampo) medicine, attenuates progression of nonalcoholic steatohepatitis in mice. J Gastroenterol (2013) 0.83
Testosterone replacement ameliorates nonalcoholic fatty liver disease in castrated male rats. Endocrinology (2013) 0.83
A novel hypothesis for the adaptive maintenance of environmental sex determination in a turtle. Proc Biol Sci (2014) 0.82
Androgen receptor roles in insulin resistance and obesity in males: the linkage of androgen-deprivation therapy to metabolic syndrome. Diabetes (2014) 0.81
The androgen receptor confers protection against diet-induced atherosclerosis, obesity, and dyslipidemia in female mice. FASEB J (2014) 0.81
The role of AMP-activated protein kinase in the androgenic potentiation of cannabinoid-induced changes in energy homeostasis. Am J Physiol Endocrinol Metab (2014) 0.79
Extranuclear Actions of the Androgen Receptor Enhance Glucose-Stimulated Insulin Secretion in the Male. Cell Metab (2016) 0.79
Testosterone replacement alters the cell size in visceral fat but not in subcutaneous fat in hypogonadal aged male rats as a late-onset hypogonadism animal model. Res Rep Urol (2015) 0.79
Fully-automated, high-throughput micro-computed tomography analysis of body composition enables therapeutic efficacy monitoring in preclinical models. Int J Obes (Lond) (2015) 0.79
Functional deficits in PAK5, PAK6 and PAK5/PAK6 knockout mice. PLoS One (2013) 0.78
Sex hormones and macronutrient metabolism. Crit Rev Food Sci Nutr (2015) 0.78
Castration influences intestinal microflora and induces abdominal obesity in high-fat diet-fed mice. Sci Rep (2016) 0.78
Hematopoietic androgen receptor deficiency promotes visceral fat deposition in male mice without impairing glucose homeostasis. Andrology (2015) 0.77
Sex-dependent expression of caveolin 1 in response to sex steroid hormones is closely associated with development of obesity in rats. PLoS One (2014) 0.76
Androgen Receptor Structure, Function and Biology: From Bench to Bedside. Clin Biochem Rev (2016) 0.76
Hypogonadism alters cecal and fecal microbiota in male mice. Gut Microbes (2016) 0.75
Testosterone, Dihydrotestosterone, Sex Hormone Binding Globulin and Incident Diabetes among Older Men: the Cardiovascular Health Study. J Clin Endocrinol Metab (2016) 0.75
Differential sensitivity of Pak5, Pak6, and Pak5/Pak6 double-knockout mice to the stimulant effects of amphetamine and exercise-induced alterations in body weight. Nutr Neurosci (2013) 0.75
PPARγ Regulates Mouse Meibocyte Differentiation and Lipid Synthesis. Ocul Surf (2016) 0.75
Transcriptome profiling of visceral adipose tissue in a novel obese rat model, WNIN/Ob & its comparison with other animal models. Indian J Med Res (2016) 0.75
Cardiovascular effects of hormone therapy for prostate cancer. Drug Healthc Patient Saf (2015) 0.75
Regulation of Estrogen Receptor α Expression in the Hypothalamus by Sex Steroids: Implication in the Regulation of Energy Homeostasis. Int J Endocrinol (2015) 0.75
ssc-miR-7134-3p regulates fat accumulation in castrated male pigs by targeting MARK4 gene. Int J Biol Sci (2017) 0.75
Sex differences in the effects of androgens acting in the central nervous system on metabolism. Dialogues Clin Neurosci (2016) 0.75
Effect of Cross-Sex Hormonal Replacement on Antioxidant Enzymes in Rat Retroperitoneal Fat Adipocytes. Oxid Med Cell Longev (2016) 0.75
Endocrine disrupting chemicals in mixture and obesity, diabetes and related metabolic disorders. World J Biol Chem (2017) 0.75
Cross-talk between miR-471-5p and autophagy component proteins regulates LC3-associated phagocytosis (LAP) of apoptotic germ cells. Nat Commun (2017) 0.75
Modulation of microRNA processing by p53. Nature (2009) 7.88
Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1. Dev Cell (2007) 5.45
Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice. Nat Cell Biol (2009) 4.78
Estrogen prevents bone loss via estrogen receptor alpha and induction of Fas ligand in osteoclasts. Cell (2007) 4.71
Retracted DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs. Nat Cell Biol (2007) 4.45
Retracted A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPAR-gamma transactivation. Nat Cell Biol (2007) 3.97
TGF-beta 1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice. J Immunol (2004) 3.79
A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing. Mol Cell (2008) 3.60
Dioxin receptor is a ligand-dependent E3 ubiquitin ligase. Nature (2007) 3.59
Modulation of oestrogen receptor signalling by association with the activated dioxin receptor. Nature (2003) 3.49
Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis. Nat Med (2012) 3.46
Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis. Science (2008) 3.38
Retracted GlcNAcylation of a histone methyltransferase in retinoic-acid-induced granulopoiesis. Nature (2009) 3.10
Retracted DNA demethylation in hormone-induced transcriptional derepression. Nature (2009) 2.90
Circulating FGF-23 is regulated by 1alpha,25-dihydroxyvitamin D3 and phosphorus in vivo. J Biol Chem (2004) 2.72
Results from a randomized trial of salvage chemotherapy followed by lestaurtinib for patients with FLT3 mutant AML in first relapse. Blood (2011) 2.66
Topical vitamin D3 and low-calcemic analogs induce thymic stromal lymphopoietin in mouse keratinocytes and trigger an atopic dermatitis. Proc Natl Acad Sci U S A (2006) 2.60
Impaired flow-dependent control of vascular tone and remodeling in P2X4-deficient mice. Nat Med (2005) 2.59
Hedgehog signaling pathway is a new therapeutic target for patients with breast cancer. Cancer Res (2004) 2.55
Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population. Diabetes (2009) 2.54
Demonstration of osteocytic perilacunar/canalicular remodeling in mice during lactation. J Bone Miner Res (2012) 2.53
Wnt and PPARgamma signaling in osteoblastogenesis and adipogenesis. Nat Rev Rheumatol (2009) 2.50
Retracted Maturation of microRNA is hormonally regulated by a nuclear receptor. Mol Cell (2009) 2.48
FLT3-mutant allelic burden and clinical status are predictive of response to FLT3 inhibitors in AML. Blood (2009) 2.44
Androgen-dependent neurodegeneration by polyglutamine-expanded human androgen receptor in Drosophila. Neuron (2002) 2.15
GlcNAcylation of histone H2B facilitates its monoubiquitination. Nature (2011) 2.14
Usefulness of mitral annular velocity in predicting exercise tolerance in patients with impaired left ventricular systolic function. Am J Cardiol (2006) 2.14
Deletion of vitamin D receptor gene in mice results in abnormal skeletal muscle development with deregulated expression of myoregulatory transcription factors. Endocrinology (2003) 2.10
Retracted Cytokines suppress adipogenesis and PPAR-gamma function through the TAK1/TAB1/NIK cascade. Nat Cell Biol (2003) 2.08
Vitamin E decreases bone mass by stimulating osteoclast fusion. Nat Med (2012) 2.04
Cyclic GMP-dependent protein kinase II is a molecular switch from proliferation to hypertrophic differentiation of chondrocytes. Genes Dev (2004) 2.00
Role of FGF10/FGFR2b signaling during mammary gland development in the mouse embryo. Development (2002) 1.99
Protein kinase C-dependent increase in reactive oxygen species (ROS) production in vascular tissues of diabetes: role of vascular NAD(P)H oxidase. J Am Soc Nephrol (2003) 1.89
Retracted The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome. Cell (2003) 1.88
Smad2 and Smad3 are redundantly essential for the TGF-beta-mediated regulation of regulatory T plasticity and Th1 development. J Immunol (2010) 1.86
Elevated levels of serum advanced glycation end products in patients with non-alcoholic steatohepatitis. J Gastroenterol Hepatol (2007) 1.85
FGF10 maintains stem cell compartment in developing mouse incisors. Development (2002) 1.84
Limited internal radiation exposure associated with resettlements to a radiation-contaminated homeland after the Fukushima Daiichi nuclear disaster. PLoS One (2013) 1.81
A new meiosis-specific cohesin complex implicated in the cohesin code for homologous pairing. EMBO Rep (2011) 1.79
Requirements for FGF3 and FGF10 during inner ear formation. Development (2003) 1.76
Retracted Nuclear receptor function requires a TFTC-type histone acetyl transferase complex. Mol Cell (2002) 1.75
Prospective randomized trial of transnasal versus peroral endoscopy using an ultrathin videoendoscope in unsedated patients. J Gastroenterol Hepatol (2007) 1.74
Suppressive function of androgen receptor in bone resorption. Proc Natl Acad Sci U S A (2003) 1.72
Osteoclast-secreted CTHRC1 in the coupling of bone resorption to formation. J Clin Invest (2013) 1.70
Induction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stress. Mol Biol Cell (2010) 1.70
Long-term inhibition of RhoA attenuates vascular contractility by enhancing endothelial NO production in an intact rabbit mesenteric artery. Circ Res (2005) 1.69
HIF1α is required for osteoclast activation by estrogen deficiency in postmenopausal osteoporosis. Proc Natl Acad Sci U S A (2013) 1.67
Involvement of Propionibacterium acnes in the augmentation of lipogenesis in hamster sebaceous glands in vivo and in vitro. J Invest Dermatol (2009) 1.67
ADRP stimulates lipid accumulation and lipid droplet formation in murine fibroblasts. Am J Physiol Endocrinol Metab (2002) 1.66
Noroviruses distinguish between type 1 and type 2 histo-blood group antigens for binding. J Virol (2008) 1.65
Augmentation of lipogenesis by 15-deoxy-Delta12,14-prostaglandin J2 in hamster sebaceous glands: identification of cytochrome P-450-mediated 15-deoxy-Delta12,14-prostaglandin J2 production. J Invest Dermatol (2005) 1.64
STAT6 Inhibits TGF-beta1-mediated Foxp3 induction through direct binding to the Foxp3 promoter, which is reverted by retinoic acid receptor. J Biol Chem (2008) 1.64
Harmonin mutations cause mechanotransduction defects in cochlear hair cells. Neuron (2009) 1.63
Thymic stromal lymphopoietin overproduced by keratinocytes in mouse skin aggravates experimental asthma. Proc Natl Acad Sci U S A (2009) 1.63
Inhibition of Stabilin-2 elevates circulating hyaluronic acid levels and prevents tumor metastasis. Proc Natl Acad Sci U S A (2012) 1.61
Wnt/beta-catenin and estrogen signaling converge in vivo. J Biol Chem (2004) 1.60
The Blimp1-Bcl6 axis is critical to regulate osteoclast differentiation and bone homeostasis. J Exp Med (2010) 1.59
Osteoclast-specific Dicer gene deficiency suppresses osteoclastic bone resorption. J Cell Biochem (2010) 1.54
A comparison of the defective granulopoiesis in childhood cyclic neutropenia and in severe congenital neutropenia. Haematologica (2005) 1.53
Tight junction proteins claudin-2 and -12 are critical for vitamin D-dependent Ca2+ absorption between enterocytes. Mol Biol Cell (2008) 1.53
Ligand-dependent switching of ubiquitin-proteasome pathways for estrogen receptor. EMBO J (2004) 1.52
Brain masculinization requires androgen receptor function. Proc Natl Acad Sci U S A (2004) 1.51
Low molecular weight phenotype of Apo(a) is a risk factor of corticosteroid-induced osteonecrosis of the femoral head after renal transplant. J Rheumatol (2007) 1.50
A histone chaperone, DEK, transcriptionally coactivates a nuclear receptor. Genes Dev (2009) 1.49
Suppression of PPAR transactivation switches cell fate of bone marrow stem cells from adipocytes into osteoblasts. Ann N Y Acad Sci (2007) 1.48
Genome-wide array-based comparative genomic hybridization of natural killer cell lymphoma/leukemia: different genomic alteration patterns of aggressive NK-cell leukemia and extranodal Nk/T-cell lymphoma, nasal type. Genes Chromosomes Cancer (2005) 1.47
Contributing factors related to efficacy of the dipeptidyl peptidase-4 inhibitor sitagliptin in Japanese patients with type 2 diabetes. Diabetes Res Clin Pract (2011) 1.46
C1galt1-deficient mice exhibit thrombocytopenia due to abnormal terminal differentiation of megakaryocytes. Blood (2013) 1.45
An HLA-A24-restricted cytotoxic T lymphocyte epitope of a tumor-associated protein, survivin. Clin Cancer Res (2002) 1.45
Premature ovarian failure in androgen receptor-deficient mice. Proc Natl Acad Sci U S A (2005) 1.44
Lifestyle changes through the use of delivered meals and dietary counseling in a single-blind study. The STYLIST study. Circ J (2012) 1.44
Retracted Ligand-induced transrepression by VDR through association of WSTF with acetylated histones. EMBO J (2005) 1.43
Insulin-like growth factor 1/insulin signaling activates androgen signaling through direct interactions of Foxo1 with androgen receptor. J Biol Chem (2007) 1.43
TDAG8 is a proton-sensing and psychosine-sensitive G-protein-coupled receptor. J Biol Chem (2004) 1.42
Comparison of clinical effectiveness between surgical and endovascular treatment for thrombotic obstruction in hemodialysis access. J Vasc Access (2011) 1.41
The androgen receptor in health and disease. Annu Rev Physiol (2012) 1.41
Prognostic significance of expressions of cell-cycle regulatory proteins in gastrointestinal stromal tumor and the relevance of the risk grade. Hum Pathol (2005) 1.41
Activation of the FGF2-FGFR1 autocrine pathway: a novel mechanism of acquired resistance to gefitinib in NSCLC. Mol Cancer Res (2013) 1.40
Perilipin 5, a lipid droplet-binding protein, protects heart from oxidative burden by sequestering fatty acid from excessive oxidation. J Biol Chem (2012) 1.40
Aryl hydrocarbon receptor suppresses intestinal carcinogenesis in ApcMin/+ mice with natural ligands. Proc Natl Acad Sci U S A (2009) 1.40
Involvement of proton-sensing TDAG8 in extracellular acidification-induced inhibition of proinflammatory cytokine production in peritoneal macrophages. J Immunol (2009) 1.39
Retracted A cell cycle-dependent co-repressor mediates photoreceptor cell-specific nuclear receptor function. EMBO J (2007) 1.39
Ingested medium-chain fatty acids are directly utilized for the acyl modification of ghrelin. Endocrinology (2005) 1.38
Glucocorticoid suppresses the canonical Wnt signal in cultured human osteoblasts. Biochem Biophys Res Commun (2005) 1.37
PKA-dependent regulation of the histone lysine demethylase complex PHF2-ARID5B. Nat Cell Biol (2011) 1.36
Retracted Transrepression by a liganded nuclear receptor via a bHLH activator through co-regulator switching. EMBO J (2004) 1.35
Blimp1-mediated repression of negative regulators is required for osteoclast differentiation. Proc Natl Acad Sci U S A (2010) 1.34
Evidence for contribution of vascular NAD(P)H oxidase to increased oxidative stress in animal models of diabetes and obesity. Free Radic Biol Med (2004) 1.34
Lack of the vitamin D receptor is associated with reduced epidermal differentiation and hair follicle growth. J Invest Dermatol (2002) 1.34
Rapid modulation of long-term depression and spinogenesis via synaptic estrogen receptors in hippocampal principal neurons. J Neurochem (2007) 1.34