Published in Nature on April 06, 2005
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The interferon-alpha signature of systemic lupus erythematosus. Lupus (2010) 1.69
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Innate immune pattern recognition: a cell biological perspective. Annu Rev Immunol (2015) 1.66
Negative regulation of signaling by a soluble form of toll-like receptor 9. Eur J Immunol (2011) 1.66
A protein associated with Toll-like receptor (TLR) 4 (PRAT4A) is required for TLR-dependent immune responses. J Exp Med (2007) 1.62
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Key role of splenic myeloid DCs in the IFN-alphabeta response to adenoviruses in vivo. PLoS Pathog (2008) 1.58
Type I interferons protect from Toll-like receptor 9-associated liver injury and regulate IL-1 receptor antagonist in mice. Gastroenterology (2010) 1.56
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Visualization of IFNbeta production by plasmacytoid versus conventional dendritic cells under specific stimulation conditions in vivo. Proc Natl Acad Sci U S A (2008) 1.44
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Suppressor of cytokine signaling-1 selectively inhibits LPS-induced IL-6 production by regulating JAK-STAT. Proc Natl Acad Sci U S A (2005) 1.39
Autoreactive B cells discriminate CpG-rich and CpG-poor DNA and this response is modulated by IFN-alpha. J Immunol (2008) 1.39
Lung epithelium as a sentinel and effector system in pneumonia--molecular mechanisms of pathogen recognition and signal transduction. Respir Res (2006) 1.39
Spatiotemporal trafficking of HIV in human plasmacytoid dendritic cells defines a persistently IFN-α-producing and partially matured phenotype. J Clin Invest (2011) 1.37
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Protective T cell immunity in mice following protein-TLR7/8 agonist-conjugate immunization requires aggregation, type I IFN, and multiple DC subsets. J Clin Invest (2011) 1.33
Functional characterization of murine interferon regulatory factor 5 (IRF-5) and its role in the innate antiviral response. J Biol Chem (2008) 1.31
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TLR7 stimulation in human plasmacytoid dendritic cells leads to the induction of early IFN-inducible genes in the absence of type I IFN. Blood (2009) 1.20
How location governs toll-like receptor signaling. Traffic (2009) 1.16
Chloroquine modulates HIV-1-induced plasmacytoid dendritic cell alpha interferon: implication for T-cell activation. Antimicrob Agents Chemother (2009) 1.16
RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA. J Exp Med (2013) 1.15
Signaling organelles of the innate immune system. Cell (2012) 1.15
Essential role for the prolyl isomerase Pin1 in Toll-like receptor signaling and type I interferon-mediated immunity. Nat Immunol (2011) 1.14
pH-Responsive nanoparticle vaccines for dual-delivery of antigens and immunostimulatory oligonucleotides. ACS Nano (2013) 1.13
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Antiinfective applications of toll-like receptor 9 agonists. Proc Am Thorac Soc (2007) 1.12
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Inhibition of the type I interferon antiviral response during arenavirus infection. Viruses (2010) 1.11
Regulation of IRF7 through cell type-specific protein stability. Biochem Biophys Res Commun (2006) 1.10
Essential requirement for IRF8 and SLC15A4 implicates plasmacytoid dendritic cells in the pathogenesis of lupus. Proc Natl Acad Sci U S A (2013) 1.10
Essential role for IKKβ in production of type 1 interferons by plasmacytoid dendritic cells. J Biol Chem (2012) 1.10
Structure-dependent immunostimulatory effect of CpG oligodeoxynucleotides and their delivery system. Int J Nanomedicine (2012) 1.09
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Inability of plasmacytoid dendritic cells to directly lyse HIV-infected autologous CD4+ T cells despite induction of tumor necrosis factor-related apoptosis-inducing ligand. J Virol (2009) 1.08
Endosomal crosstalk: meeting points for signaling pathways. Trends Cell Biol (2012) 1.08
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DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response. Nature (2007) 13.56
IRF-7 is the master regulator of type-I interferon-dependent immune responses. Nature (2005) 13.23
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IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors. Nat Rev Immunol (2006) 7.98
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The IRF family transcription factors in immunity and oncogenesis. Annu Rev Immunol (2008) 6.60
Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors. Nature (2005) 5.37
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Control of cell polarity and motility by the PtdIns(3,4,5)P3 phosphatase SHIP1. Nat Cell Biol (2006) 3.19
Comparing antibody and small-molecule therapies for cancer. Nat Rev Cancer (2006) 3.19
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Essential role of IRF-3 in lipopolysaccharide-induced interferon-beta gene expression and endotoxin shock. Biochem Biophys Res Commun (2003) 2.37
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The contribution of transcription factor IRF1 to the interferon-gamma-interleukin 12 signaling axis and TH1 versus TH-17 differentiation of CD4+ T cells. Nat Immunol (2007) 2.15
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A critical link between Toll-like receptor 3 and type II interferon signaling pathways in antiviral innate immunity. Proc Natl Acad Sci U S A (2008) 1.75
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