Published in Nat Rev Immunol on February 03, 2012
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Identification of host cell factors required for intoxication through use of modified cholera toxin. J Cell Biol (2011) 1.47
The caspase-like sites of proteasomes, their substrate specificity, new inhibitors and substrates, and allosteric interactions with the trypsin-like sites. J Biol Chem (2003) 1.46
Dissection of the dislocation pathway for type I membrane proteins with a new small molecule inhibitor, eeyarestatin. Mol Biol Cell (2004) 1.44
Discovery of CD8+ T cell epitopes in Chlamydia trachomatis infection through use of caged class I MHC tetramers. Proc Natl Acad Sci U S A (2008) 1.43
Site-specific protein labeling via sortase-mediated transpeptidation. Curr Protoc Protein Sci (2009) 1.43
Viral modulation of antigen presentation: manipulation of cellular targets in the ER and beyond. Immunol Rev (2005) 1.43
Using a small molecule inhibitor of peptide: N-glycanase to probe its role in glycoprotein turnover. Chem Biol (2004) 1.42
Quality and quantity control at the endoplasmic reticulum. Curr Opin Cell Biol (2010) 1.42
Effects of PS-341 on the activity and composition of proteasomes in multiple myeloma cells. Cancer Res (2005) 1.39
Visualization of the ER-to-cytosol dislocation reaction of a type I membrane protein. EMBO J (2002) 1.39
Rapid turnover of unspliced Xbp-1 as a factor that modulates the unfolded protein response. J Biol Chem (2005) 1.39
Preparation of unnatural N-to-N and C-to-C protein fusions. Proc Natl Acad Sci U S A (2012) 1.38
Granulin is a soluble cofactor for toll-like receptor 9 signaling. Immunity (2011) 1.36
Kaposi's sarcoma-associated herpesvirus K3 utilizes the ubiquitin-proteasome system in routing class major histocompatibility complexes to late endocytic compartments. J Virol (2002) 1.36
Preferred in vivo ubiquitination sites. Bioinformatics (2004) 1.36
The CD8 T-cell response against murine gammaherpesvirus 68 is directed toward a broad repertoire of epitopes from both early and late antigens. J Virol (2008) 1.35
Lipid modification of proteins through sortase-catalyzed transpeptidation. J Am Chem Soc (2008) 1.34
Enzymatic blockade of the ubiquitin-proteasome pathway. PLoS Biol (2011) 1.33
A closer look at proteolysis and MHC-class-II-restricted antigen presentation. Curr Opin Immunol (2002) 1.32
Cellular internalization of cytolethal distending toxin: a new end to a known pathway. Cell Microbiol (2005) 1.32
A straight path to circular proteins. J Biol Chem (2009) 1.31
Chlamydia trachomatis-derived deubiquitinating enzymes in mammalian cells during infection. Mol Microbiol (2006) 1.30
The human cytomegalovirus US10 gene product delays trafficking of major histocompatibility complex class I molecules. J Virol (2002) 1.28
Fungal recognition is mediated by the association of dectin-1 and galectin-3 in macrophages. Proc Natl Acad Sci U S A (2011) 1.28
Helicobacter pylori cytotoxin-associated gene A (CagA) subverts the apoptosis-stimulating protein of p53 (ASPP2) tumor suppressor pathway of the host. Proc Natl Acad Sci U S A (2011) 1.27
Membrane-specific, host-derived factors are required for US2- and US11-mediated degradation of major histocompatibility complex class I molecules. J Biol Chem (2001) 1.27
Tubulation of class II MHC compartments is microtubule dependent and involves multiple endolysosomal membrane proteins in primary dendritic cells. J Immunol (2007) 1.27
Chemistry in living cells: detection of active proteasomes by a two-step labeling strategy. Angew Chem Int Ed Engl (2003) 1.25
Differential regulation of effector- and central-memory responses to Toxoplasma gondii Infection by IL-12 revealed by tracking of Tgd057-specific CD8+ T cells. PLoS Pathog (2010) 1.25
Profiling antibody responses by multiparametric analysis of primary B cells. Proc Natl Acad Sci U S A (2008) 1.25
Mechanism-based probe for the analysis of cathepsin cysteine proteases in living cells. ACS Chem Biol (2006) 1.25
Site-specific C-terminal and internal loop labeling of proteins using sortase-mediated reactions. Nat Protoc (2013) 1.25
Monovalent ligation of the B cell receptor induces receptor activation but fails to promote antigen presentation. Proc Natl Acad Sci U S A (2006) 1.23
Substrate filtering by the active site crossover loop in UCHL3 revealed by sortagging and gain-of-function mutations. J Biol Chem (2008) 1.22
Sortase-catalyzed transformations that improve the properties of cytokines. Proc Natl Acad Sci U S A (2011) 1.21
Site-specific N-terminal labeling of proteins using sortase-mediated reactions. Nat Protoc (2013) 1.19
Human cytomegalovirus protein US11 provokes an unfolded protein response that may facilitate the degradation of class I major histocompatibility complex products. J Virol (2005) 1.19
Protein unfolding is not a prerequisite for endoplasmic reticulum-to-cytosol dislocation. J Biol Chem (2002) 1.19
Bruton's Tyrosine Kinase (BTK) and Vav1 contribute to Dectin1-dependent phagocytosis of Candida albicans in macrophages. PLoS Pathog (2013) 1.19