Published in J Biol Chem on February 24, 2010
SUMO Losing Balance: SUMO Proteases Disrupt SUMO Homeostasis to Facilitate Cancer Development and Progression. Genes Cancer (2010) 1.42
Human pathogens and the host cell SUMOylation system. J Virol (2011) 1.31
Redox regulation of the stability of the SUMO protease SENP3 via interactions with CHIP and Hsp90. EMBO J (2010) 1.11
Sumoylation and regulation of cardiac gene expression. Circ Res (2010) 1.08
Arsenic-induced SUMO-dependent recruitment of RNF4 into PML nuclear bodies. Mol Biol Cell (2010) 1.07
SUMOylation-Mediated Regulation of Cell Cycle Progression and Cancer. Trends Biochem Sci (2015) 0.95
Dimerumic acid inhibits SW620 cell invasion by attenuating H₂O₂-mediated MMP-7 expression via JNK/C-Jun and ERK/C-Fos activation in an AP-1-dependent manner. Int J Biol Sci (2011) 0.93
The SUMO protease SENP6 is a direct regulator of PML nuclear bodies. Mol Biol Cell (2010) 0.91
SENP1 deSUMOylates and regulates Pin1 protein activity and cellular function. Cancer Res (2013) 0.90
Post-translational modifications of PML: consequences and implications. Front Oncol (2013) 0.88
Advances in the development of SUMO specific protease (SENP) inhibitors. Comput Struct Biotechnol J (2015) 0.88
Covalent small ubiquitin-like modifier (SUMO) modification of Maf1 protein controls RNA polymerase III-dependent transcription repression. J Biol Chem (2013) 0.87
Small ubiquitin-like modifier 1-3 conjugation [corrected] is activated in human astrocytic brain tumors and is required for glioblastoma cell survival. Cancer Sci (2012) 0.86
De-SUMOylation of FOXC2 by SENP3 promotes the epithelial-mesenchymal transition in gastric cancer cells. Oncotarget (2014) 0.85
The biphasic redox sensing of SENP3 accounts for the HIF-1 transcriptional activity shift by oxidative stress. Acta Pharmacol Sin (2012) 0.83
Transcriptional repression of estrogen receptor α signaling by SENP2 in breast cancer cells. Mol Endocrinol (2013) 0.82
SUMOylation and SUMO-interacting motif (SIM) of metastasis tumor antigen 1 (MTA1) synergistically regulate its transcriptional repressor function. J Biol Chem (2011) 0.80
SUMO-Specific Protease 2 (SENP2) Is an Important Regulator of Fatty Acid Metabolism in Skeletal Muscle. Diabetes (2015) 0.79
Overexpression of SENP3 in oral squamous cell carcinoma and its association with differentiation. Oncol Rep (2013) 0.79
The effects of buthionine sulfoximine on the proliferation and apoptosis of biliary tract cancer cells induced by cisplatin and gemcitabine. Oncol Lett (2015) 0.78
Inhibition of SENP5 suppresses cell growth and promotes apoptosis in osteosarcoma cells. Exp Ther Med (2014) 0.78
Expression and cell distribution of SENP3 in the cerebral cortex after experimental subarachnoid hemorrhage in rats: a pilot study. Cell Mol Neurobiol (2014) 0.77
Control of antioxidative response by the tumor suppressor protein PML through regulating Nrf2 activity. Mol Biol Cell (2014) 0.77
SENP3 regulates the global protein turnover and the Sp1 level via antagonizing SUMO2/3-targeted ubiquitination and degradation. Protein Cell (2015) 0.77
SUMOylation and SENP3 regulate STAT3 activation in head and neck cancer. Oncogene (2016) 0.76
SUMO and the robustness of cancer. Nat Rev Cancer (2017) 0.75
Phenylethyl isothiocyanate reverses cisplatin resistance in biliary tract cancer cells via glutathionylation-dependent degradation of Mcl-1. Oncotarget (2016) 0.75
SUMO-specific protease 3 is a key regulator for hepatic lipid metabolism in non-alcoholic fatty liver disease. Sci Rep (2016) 0.75
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PML nuclear bodies: dynamic sensors of DNA damage and cellular stress. Bioessays (2004) 2.32
Redox control of cell fate by MAP kinase: physiological roles of ASK1-MAP kinase pathway in stress signaling. Biochim Biophys Acta (2008) 2.31
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The SUMO protease SENP5 is required to maintain mitochondrial morphology and function. J Cell Sci (2007) 2.12
Hydrogen peroxide activates NF-kappa B through tyrosine phosphorylation of I kappa B alpha and serine phosphorylation of p65: evidence for the involvement of I kappa B alpha kinase and Syk protein-tyrosine kinase. J Biol Chem (2003) 2.05
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The SUMO-specific protease SENP5 is required for cell division. Mol Cell Biol (2006) 1.81
A novel mammalian Smt3-specific isopeptidase 1 (SMT3IP1) localized in the nucleolus at interphase. Eur J Biochem (2000) 1.75
Transient global cerebral ischemia induces a massive increase in protein sumoylation. J Cereb Blood Flow Metab (2007) 1.74
Emodin enhances cytotoxicity of chemotherapeutic drugs in prostate cancer cells: the mechanisms involve ROS-mediated suppression of multidrug resistance and hypoxia inducible factor-1. Cancer Biol Ther (2007) 1.70
SUSP1 antagonizes formation of highly SUMO2/3-conjugated species. J Cell Biol (2006) 1.67
Regulation of apoptosis by PML and the PML-NBs. Oncogene (2008) 1.67
Global shifts in protein sumoylation in response to electrophile and oxidative stress. Chem Res Toxicol (2004) 1.57
Dual modification of BMAL1 by SUMO2/3 and ubiquitin promotes circadian activation of the CLOCK/BMAL1 complex. Mol Cell Biol (2008) 1.52
Increased protein SUMOylation following focal cerebral ischemia. Neuropharmacology (2007) 1.48
The nucleolar SUMO-specific protease SENP3 reverses SUMO modification of nucleophosmin and is required for rRNA processing. EMBO Rep (2008) 1.47
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Size, position and dynamic behavior of PML nuclear bodies following cell stress as a paradigm for supramolecular trafficking and assembly. J Cell Sci (2003) 1.45
Loss of SUMO1 in mice affects RanGAP1 localization and formation of PML nuclear bodies, but is not lethal as it can be compensated by SUMO2 or SUMO3. J Cell Sci (2008) 1.44
SENP3 is responsible for HIF-1 transactivation under mild oxidative stress via p300 de-SUMOylation. EMBO J (2009) 1.41
SUMO on the road to neurodegeneration. Biochim Biophys Acta (2007) 1.35
Stabilization of PML nuclear localization by conjugation and oligomerization of SUMO-3. Oncogene (2005) 1.33
Expression of SUMO-2/3 induced senescence through p53- and pRB-mediated pathways. J Biol Chem (2006) 1.26
New insights into the role of PML in tumour suppression. Cell Res (2008) 1.22
Heat shock and Cd2+ exposure regulate PML and Daxx release from ND10 by independent mechanisms that modify the induction of heat-shock proteins 70 and 25 differently. J Cell Sci (2003) 1.20
RanBP2 and SENP3 function in a mitotic SUMO2/3 conjugation-deconjugation cycle on Borealin. Mol Biol Cell (2008) 1.19
Arf-induced turnover of the nucleolar nucleophosmin-associated SUMO-2/3 protease Senp3. Cell Cycle (2008) 1.13
Redox signaling and cancer: the role of "labile" iron. Cancer Lett (2008) 1.10
Isoforms of the promyelocytic leukemia protein differ in their effects on ND10 organization. Exp Cell Res (2005) 1.03
SUMO-specific proteases and the cell cycle. An essential role for SENP5 in cell proliferation. Cell Cycle (2006) 0.98
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The IL-6 family of cytokines modulates STAT3 activation by desumoylation of PML through SENP1 induction. Biochem Biophys Res Commun (2008) 0.91
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Atypical mechanism of NF-kappaB activation during reoxygenation stress in microvascular endothelium: a role for tyrosine kinases. Free Radic Biol Med (2002) 0.86
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A human gut microbial gene catalogue established by metagenomic sequencing. Nature (2010) 43.63
A draft sequence of the rice genome (Oryza sativa L. ssp. indica). Science (2002) 42.78
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SOAPdenovo2: an empirically improved memory-efficient short-read de novo assembler. Gigascience (2012) 20.89
The genome sequence of the malaria mosquito Anopheles gambiae. Science (2002) 20.36
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
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SNP detection for massively parallel whole-genome resequencing. Genome Res (2009) 15.96
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From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus. Nature (2010) 12.07
A metagenome-wide association study of gut microbiota in type 2 diabetes. Nature (2012) 11.68
piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells. Nature (2009) 11.27
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Open-source genomic analysis of Shiga-toxin-producing E. coli O104:H4. N Engl J Med (2011) 7.11
The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models. Nat Biotechnol (2010) 7.08
Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia. Nat Genet (2010) 7.08
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Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. Nat Genet (2009) 6.42
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Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder. Nat Genet (2011) 5.73
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New loci associated with kidney function and chronic kidney disease. Nat Genet (2010) 5.58
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Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells. Science (2010) 5.50
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Single-cell exome sequencing and monoclonal evolution of a JAK2-negative myeloproliferative neoplasm. Cell (2012) 5.16
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SUMO-specific protease 1 is essential for stabilization of HIF1alpha during hypoxia. Cell (2007) 4.46
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Hepatocyte growth factor induces gefitinib resistance of lung adenocarcinoma with epidermal growth factor receptor-activating mutations. Cancer Res (2008) 4.30
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