Published in Protein Eng Des Sel on August 27, 2008
Proteome scale characterization of human S-acylated proteins in lipid raft-enriched and non-raft membranes. Mol Cell Proteomics (2009) 2.16
PDZ domains and their binding partners: structure, specificity, and modification. Cell Commun Signal (2010) 2.07
Where is mTOR and what is it doing there? J Cell Biol (2013) 1.91
A novel family of Toxoplasma IMC proteins displays a hierarchical organization and functions in coordinating parasite division. PLoS Pathog (2010) 1.70
A family of intermediate filament-like proteins is sequentially assembled into the cytoskeleton of Toxoplasma gondii. Cell Microbiol (2011) 1.50
GPS-SNO: computational prediction of protein S-nitrosylation sites with a modified GPS algorithm. PLoS One (2010) 1.40
Ion channel regulation by protein palmitoylation. J Biol Chem (2011) 1.25
A forward genetic screen reveals that calcium-dependent protein kinase 3 regulates egress in Toxoplasma. PLoS Pathog (2012) 1.23
A Toxoplasma MORN1 null mutant undergoes repeated divisions but is defective in basal assembly, apicoplast division and cytokinesis. PLoS One (2010) 1.21
Novel membrane-associated androgen receptor splice variant potentiates proliferative and survival responses in prostate cancer cells. J Biol Chem (2011) 1.21
Proteomic analysis of palmitoylated platelet proteins. Blood (2011) 1.14
S-acylation-dependent association of the calcium sensor CBL2 with the vacuolar membrane is essential for proper abscisic acid responses. Cell Res (2012) 1.05
Multiple palmitoyltransferases are required for palmitoylation-dependent regulation of large conductance calcium- and voltage-activated potassium channels. J Biol Chem (2010) 1.04
Palmitoylation regulates epidermal homeostasis and hair follicle differentiation. PLoS Genet (2009) 1.04
Pannexin 2 is expressed by postnatal hippocampal neural progenitors and modulates neuronal commitment. J Biol Chem (2010) 1.03
The physiology of protein S-acylation. Physiol Rev (2015) 1.03
Mice with alopecia, osteoporosis, and systemic amyloidosis due to mutation in Zdhhc13, a gene coding for palmitoyl acyltransferase. PLoS Genet (2010) 1.02
Characterization of subcellular localization of duck enteritis virus UL51 protein. Virol J (2009) 1.01
Intracellular trafficking of guanylate-binding proteins is regulated by heterodimerization in a hierarchical manner. PLoS One (2010) 1.01
Palmitoylation of the S0-S1 linker regulates cell surface expression of voltage- and calcium-activated potassium (BK) channels. J Biol Chem (2010) 0.98
Palmitoylation of hepatitis C virus core protein is important for virion production. J Biol Chem (2009) 0.98
Fat chance! Getting a grip on a slippery modification. ACS Chem Biol (2012) 0.98
Membrane recruitment of endogenous LRRK2 precedes its potent regulation of autophagy. Hum Mol Genet (2014) 0.98
Targeted proteomic dissection of Toxoplasma cytoskeleton sub-compartments using MORN1. Cytoskeleton (Hoboken) (2012) 0.97
Global analysis of protein palmitoylation in African trypanosomes. Eukaryot Cell (2010) 0.97
Sequence analysis of the genome of piscine orthoreovirus (PRV) associated with heart and skeletal muscle inflammation (HSMI) in Atlantic salmon (Salmo salar). PLoS One (2013) 0.96
Plasticity between MyoC- and MyoA-glideosomes: an example of functional compensation in Toxoplasma gondii invasion. PLoS Pathog (2014) 0.95
Evolution of the globin gene family in deuterostomes: lineage-specific patterns of diversification and attrition. Mol Biol Evol (2012) 0.94
A membrane-bound vertebrate globin. PLoS One (2011) 0.94
The inhibitory effect of phospholemman on the sodium pump requires its palmitoylation. J Biol Chem (2011) 0.92
Interacting regions of CD81 and two of its partners, EWI-2 and EWI-2wint, and their effect on hepatitis C virus infection. J Biol Chem (2011) 0.92
Differential regulation of two palmitoylation sites in the cytoplasmic tail of the beta1-adrenergic receptor. J Biol Chem (2011) 0.92
Emerging roles for protein S-palmitoylation in immunity from chemical proteomics. Curr Opin Chem Biol (2013) 0.92
Palmitoylation influences the function and pharmacology of sodium channels. Proc Natl Acad Sci U S A (2011) 0.91
Arabidopsis tetraspanins are confined to discrete expression domains and cell types in reproductive tissues and form homo- and heterodimers when expressed in yeast. Plant Physiol (2013) 0.91
SwissPalm: Protein Palmitoylation database. F1000Res (2015) 0.91
Annotation of microsporidian genomes using transcriptional signals. Nat Commun (2012) 0.90
NOCA-1 functions with γ-tubulin and in parallel to Patronin to assemble non-centrosomal microtubule arrays in C. elegans. Elife (2015) 0.90
An electrostatic switch controls palmitoylation of the large conductance voltage- and calcium-activated potassium (BK) channel. J Biol Chem (2011) 0.90
Palmitoylation of gephyrin controls receptor clustering and plasticity of GABAergic synapses. PLoS Biol (2014) 0.89
In silico screening for palmitoyl substrates reveals a role for DHHC1/3/10 (zDHHC1/3/11)-mediated neurochondrin palmitoylation in its targeting to Rab5-positive endosomes. J Biol Chem (2013) 0.89
Acylation in trypanosomatids: an essential process and potential drug target. Trends Parasitol (2014) 0.88
Initial characteristics of RbcX proteins from Arabidopsis thaliana. Plant Mol Biol (2011) 0.87
Novel missense mutations in exon 15 of desmoglein-2: role of the intracellular cadherin segment in arrhythmogenic right ventricular cardiomyopathy? Heart Rhythm (2010) 0.87
Reversible palmitoylation regulates surface stability of AMPA receptors in the nucleus accumbens in response to cocaine in vivo. Biol Psychiatry (2011) 0.87
Chemoproteomics reveals Toll-like receptor fatty acylation. BMC Biol (2014) 0.86
The autodepalmitoylating activity of APT maintains the spatial organization of palmitoylated membrane proteins. Biophys J (2014) 0.86
The maize high-lysine mutant opaque7 is defective in an acyl-CoA synthetase-like protein. Genetics (2011) 0.86
Palmitoylation of the β4-subunit regulates surface expression of large conductance calcium-activated potassium channel splice variants. J Biol Chem (2013) 0.86
Differential expression of CPKs and cytosolic Ca2+ variation in resistant and susceptible apple cultivars (Malus x domestica) in response to the pathogen Erwinia amylovora and mechanical wounding. BMC Genomics (2013) 0.85
Evolution and functional characterisation of melanopsins in a deep-sea chimaera (elephant shark, Callorhinchus milii). PLoS One (2012) 0.85
ORF7 of varicella-zoster virus is a neurotropic factor. J Virol (2012) 0.85
The apical complex provides a regulated gateway for secretion of invasion factors in Toxoplasma. PLoS Pathog (2014) 0.85
The apicomplexan glideosome and adhesins - Structures and function. J Struct Biol (2015) 0.84
Modulatory mechanisms and multiple functions of somatodendritic A-type K (+) channel auxiliary subunits. Front Cell Neurosci (2014) 0.84
miR-786 regulation of a fatty-acid elongase contributes to rhythmic calcium-wave initiation in C. elegans. Curr Biol (2012) 0.84
The palmitoyltransferase Approximated promotes growth via the Hippo pathway by palmitoylation of Fat. J Cell Biol (2016) 0.84
TXNDC5, a newly discovered disulfide isomerase with a key role in cell physiology and pathology. Int J Mol Sci (2014) 0.84
PalmPred: an SVM based palmitoylation prediction method using sequence profile information. PLoS One (2014) 0.84
Human germline and pan-cancer variomes and their distinct functional profiles. Nucleic Acids Res (2014) 0.84
Genome-wide survey and expression analysis of calcium-dependent protein kinase in Gossypium raimondii. PLoS One (2014) 0.83
Curation of the Mammalian Palmitoylome Indicates a Pivotal Role for Palmitoylation in Diseases and Disorders of the Nervous System and Cancers. PLoS Comput Biol (2015) 0.83
Helix 8 of the ligand binding domain of the glucocorticoid receptor (GR) is essential for ligand binding. Mol Cell Endocrinol (2015) 0.83
Palmitoylation of LIM Kinase-1 ensures spine-specific actin polymerization and morphological plasticity. Elife (2015) 0.83
FAD synthesis and degradation in the nucleus create a local flavin cofactor pool. J Biol Chem (2013) 0.83
Ion channel regulation by protein S-acylation. J Gen Physiol (2014) 0.82
Regulation of large conductance calcium- and voltage-activated potassium (BK) channels by S-palmitoylation. Biochem Soc Trans (2013) 0.82
Proteome analysis of Cry4Ba toxin-interacting Aedes aegypti lipid rafts using geLC-MS/MS. J Proteome Res (2012) 0.82
Plant plasma membrane-bound staphylococcal-like DNases as a novel class of eukaryotic nucleases. BMC Plant Biol (2012) 0.82
Rice hypersensitive induced reaction protein 1 (OsHIR1) associates with plasma membrane and triggers hypersensitive cell death. BMC Plant Biol (2010) 0.82
Plasma membrane localization is essential for Oryza sativa Pto-interacting protein 1a-mediated negative regulation of immune signaling in rice. Plant Physiol (2014) 0.82
A novel role of the yeast CaaX protease Ste24 in chitin synthesis. Mol Biol Cell (2010) 0.82
Interplay between phosphorylation and palmitoylation mediates plasma membrane targeting and sorting of GAP43. Mol Biol Cell (2014) 0.81
Palmitoylation of the immunity related GTPase, Irgm1: impact on membrane localization and ability to promote mitochondrial fission. PLoS One (2014) 0.81
S-palmitoylation represents a novel mechanism regulating the mitochondrial targeting of BAX and initiation of apoptosis. Cell Death Dis (2014) 0.81
Proteomic analysis of the cilia membrane of Paramecium tetraurelia. J Proteomics (2012) 0.81
Global Analysis of Palmitoylated Proteins in Toxoplasma gondii. Cell Host Microbe (2015) 0.81
The globin gene repertoire of lampreys: convergent evolution of hemoglobin and myoglobin in jawed and jawless vertebrates. Mol Biol Evol (2014) 0.81
Multiple post-translational modifications affect heterologous protein synthesis. J Biol Chem (2012) 0.81
A comparative analysis of trypanosomatid SNARE proteins. Parasitol Int (2013) 0.81
Analysis of familial hemophagocytic lymphohistiocytosis type 4 (FHL-4) mutant proteins reveals that S-acylation is required for the function of syntaxin 11 in natural killer cells. PLoS One (2014) 0.80
Identifying cellular pathways modulated by Drosophila palmitoyl-protein thioesterase 1 function. Neurobiol Dis (2010) 0.80
Recognition of the protein kinase AVRPPHB SUSCEPTIBLE1 by the disease resistance protein RESISTANCE TO PSEUDOMONAS SYRINGAE5 is dependent on s-acylation and an exposed loop in AVRPPHB SUSCEPTIBLE1. Plant Physiol (2013) 0.80
Genome-Wide Identification of Calcium Dependent Protein Kinase Gene Family in Plant Lineage Shows Presence of Novel D-x-D and D-E-L Motifs in EF-Hand Domain. Front Plant Sci (2015) 0.80
GPS-Lipid: a robust tool for the prediction of multiple lipid modification sites. Sci Rep (2016) 0.80
The palmitoylation state of PMP22 modulates epithelial cell morphology and migration. ASN Neuro (2012) 0.80
Stable expression and function of the inositol 1,4,5-triphosphate receptor requires palmitoylation by a DHHC6/selenoprotein K complex. Proc Natl Acad Sci U S A (2014) 0.80
The Road not Taken: Less Traveled Roads from the TGN to the Plasma Membrane. Membranes (Basel) (2015) 0.80
Legionella pneumophila Effector LpdA Is a Palmitoylated Phospholipase D Virulence Factor. Infect Immun (2015) 0.80
A redox signalling globin is essential for reproduction in Caenorhabditis elegans. Nat Commun (2015) 0.80
Genome-wide identification of calcium-dependent protein kinases in soybean and analyses of their transcriptional responses to insect herbivory and drought stress. Sci Rep (2016) 0.80
S-palmitoylation and s-oleoylation of rabbit and pig sarcolipin. J Biol Chem (2014) 0.79
Cysteine palmitoylation of the γ subunit has a dominant role in modulating activity of the epithelial sodium channel. J Biol Chem (2014) 0.79
Agonist-dependent signaling by group I metabotropic glutamate receptors is regulated by association with lipid domains. J Biol Chem (2013) 0.79
The Arabidopsis Protein Phosphatase PP2C38 Negatively Regulates the Central Immune Kinase BIK1. PLoS Pathog (2016) 0.78
Palmitoylation of plakophilin is required for desmosome assembly. J Cell Sci (2014) 0.78
Germline and somatic mutations in the MTOR gene in focal cortical dysplasia and epilepsy. Neurol Genet (2016) 0.78
Palmitoylation-dependent membrane localization of the rice resistance protein pit is critical for the activation of the small GTPase OsRac1. J Biol Chem (2014) 0.78
DHCR24 associates strongly with the endoplasmic reticulum beyond predicted membrane domains: implications for the activities of this multi-functional enzyme. Biosci Rep (2014) 0.78
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Global analysis of protein palmitoylation in yeast. Cell (2006) 4.43
Palmitoylation of intracellular signaling proteins: regulation and function. Annu Rev Biochem (2004) 4.34
Trafficking and signaling by fatty-acylated and prenylated proteins. Nat Chem Biol (2006) 4.11
Palmitoylation of ligands, receptors, and intracellular signaling molecules. Sci STKE (2006) 3.56
The yeast DHHC cysteine-rich domain protein Akr1p is a palmitoyl transferase. J Cell Biol (2002) 3.48
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Protein palmitoylation: a regulator of neuronal development and function. Nat Rev Neurosci (2002) 2.32
N-terminal N-myristoylation of proteins: prediction of substrate proteins from amino acid sequence. J Mol Biol (2002) 2.18
Palmitoylation-dependent protein sorting. J Cell Biol (2007) 2.14
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Identification of GPI anchor attachment signals by a Kohonen self-organizing map. Bioinformatics (2005) 1.99
Refinement and prediction of protein prenylation motifs. Genome Biol (2005) 1.84
N-terminal N-myristoylation of proteins: refinement of the sequence motif and its taxon-specific differences. J Mol Biol (2002) 1.72
N-Terminal myristoylation predictions by ensembles of neural networks. Proteomics (2004) 1.67
Predicting N-terminal myristoylation sites in plant proteins. BMC Genomics (2004) 1.53
On the mechanism of protein palmitoylation. EMBO Rep (2004) 1.52
CSS-Palm: palmitoylation site prediction with a clustering and scoring strategy (CSS). Bioinformatics (2006) 1.42
Palmitoylation is required for efficient Fas cell death signaling. EMBO J (2006) 1.33
The palmitoylation of metastasis suppressor KAI1/CD82 is important for its motility- and invasiveness-inhibitory activity. Cancer Res (2004) 1.22
Prediction of lipid posttranslational modifications and localization signals from protein sequences: big-Pi, NMT and PTS1. Nucleic Acids Res (2003) 1.14
NBA-Palm: prediction of palmitoylation site implemented in Naïve Bayes algorithm. BMC Bioinformatics (2006) 1.12
Cellular palmitoylation and trafficking of lipidated peptides. J Lipid Res (2007) 1.07
GPS 2.0, a tool to predict kinase-specific phosphorylation sites in hierarchy. Mol Cell Proteomics (2008) 4.33
CCL18 from tumor-associated macrophages promotes breast cancer metastasis via PITPNM3. Cancer Cell (2011) 3.31
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Internalization of NK cells into tumor cells requires ezrin and leads to programmed cell-in-cell death. Cell Res (2009) 2.07
Direct interaction between survivin and Smac/DIABLO is essential for the anti-apoptotic activity of survivin during taxol-induced apoptosis. J Biol Chem (2003) 2.06
SUMOsp: a web server for sumoylation site prediction. Nucleic Acids Res (2006) 1.88
Structure of a CENP-A-histone H4 heterodimer in complex with chaperone HJURP. Genes Dev (2011) 1.87
A novel set of DNA methylation markers in urine sediments for sensitive/specific detection of bladder cancer. Clin Cancer Res (2007) 1.77
Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis. Cell Res (2007) 1.71
Expression of seven main Rho family members in gastric carcinoma. Biochem Biophys Res Commun (2004) 1.63
NEK2A interacts with MAD1 and possibly functions as a novel integrator of the spindle checkpoint signaling. J Biol Chem (2004) 1.58
Structural disorder in the complex of human pregnane X receptor and the macrolide antibiotic rifampicin. Mol Endocrinol (2005) 1.55
GPS 2.1: enhanced prediction of kinase-specific phosphorylation sites with an algorithm of motif length selection. Protein Eng Des Sel (2010) 1.53
Structural basis of heroin and cocaine metabolism by a promiscuous human drug-processing enzyme. Nat Struct Biol (2003) 1.46
Human Zwint-1 specifies localization of Zeste White 10 to kinetochores and is essential for mitotic checkpoint signaling. J Biol Chem (2004) 1.44
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CSS-Palm: palmitoylation site prediction with a clustering and scoring strategy (CSS). Bioinformatics (2006) 1.42
GPS-SNO: computational prediction of protein S-nitrosylation sites with a modified GPS algorithm. PLoS One (2010) 1.40
Stabilization of PML nuclear localization by conjugation and oligomerization of SUMO-3. Oncogene (2005) 1.33
Phosphorylation of HsMis13 by Aurora B kinase is essential for assembly of functional kinetochore. J Biol Chem (2008) 1.30
Nudel modulates kinetochore association and function of cytoplasmic dynein in M phase. Mol Biol Cell (2007) 1.30
Influence of mutations in hepatitis B virus surface protein on viral antigenicity and phenotype in occult HBV strains from blood donors. J Hepatol (2012) 1.29
Human NUF2 interacts with centromere-associated protein E and is essential for a stable spindle microtubule-kinetochore attachment. J Biol Chem (2007) 1.27
Prediction of Nepsilon-acetylation on internal lysines implemented in Bayesian Discriminant Method. Biochem Biophys Res Commun (2006) 1.24
PLK1 phosphorylates mitotic centromere-associated kinesin and promotes its depolymerase activity. J Biol Chem (2010) 1.24
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Characterization of protein kinase A-mediated phosphorylation of ezrin in gastric parietal cell activation. J Biol Chem (2003) 1.19
PhosSNP for systematic analysis of genetic polymorphisms that influence protein phosphorylation. Mol Cell Proteomics (2009) 1.15
Systematic analysis of protein phosphorylation networks from phosphoproteomic data. Mol Cell Proteomics (2012) 1.15
A genome-wide analysis of sumoylation-related biological processes and functions in human nucleus. FEBS Lett (2005) 1.15
PALS1 specifies the localization of ezrin to the apical membrane of gastric parietal cells. J Biol Chem (2005) 1.15
PKA-mediated protein phosphorylation regulates ezrin-WWOX interaction. Biochem Biophys Res Commun (2006) 1.14
NBA-Palm: prediction of palmitoylation site implemented in Naïve Bayes algorithm. BMC Bioinformatics (2006) 1.12
CENP-E kinesin interacts with SKAP protein to orchestrate accurate chromosome segregation in mitosis. J Biol Chem (2011) 1.12
Evaluation of polyamidoamine (PAMAM) dendrimers as drug carriers of anti-bacterial drugs using sulfamethoxazole (SMZ) as a model drug. Eur J Med Chem (2006) 1.12
Phosphorylation of ezrin on threonine 567 produces a change in secretory phenotype and repolarizes the gastric parietal cell. J Cell Sci (2005) 1.12
Rho kinase phosphorylation promotes ezrin-mediated metastasis in hepatocellular carcinoma. Cancer Res (2011) 1.11
CPSS: a computational platform for the analysis of small RNA deep sequencing data. Bioinformatics (2012) 1.10
PinX1 is a novel microtubule-binding protein essential for accurate chromosome segregation. J Biol Chem (2009) 1.09
EB1 acetylation by P300/CBP-associated factor (PCAF) ensures accurate kinetochore-microtubule interactions in mitosis. Proc Natl Acad Sci U S A (2012) 1.09
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Apoptosis of rat granulosa cells after staurosporine and serum withdrawal is suppressed by adenovirus-directed overexpression of prohibitin. Endocrinology (2006) 1.08
CPLA 1.0: an integrated database of protein lysine acetylation. Nucleic Acids Res (2010) 1.08
Reversal of the malignant phenotype of gastric cancer cells by inhibition of RhoA expression and activity. Clin Cancer Res (2004) 1.08
PRC1 cooperates with CLASP1 to organize central spindle plasticity in mitosis. J Biol Chem (2009) 1.06
CENP-U cooperates with Hec1 to orchestrate kinetochore-microtubule attachment. J Biol Chem (2010) 1.06
Mitotic regulator SKAP forms a link between kinetochore core complex KMN and dynamic spindle microtubules. J Biol Chem (2012) 1.05
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A summary of computational resources for protein phosphorylation. Curr Protein Pept Sci (2010) 1.05
Proteomic identification and functional characterization of a novel ARF6 GTPase-activating protein, ACAP4. Mol Cell Proteomics (2006) 1.05
GPS-CCD: a novel computational program for the prediction of calpain cleavage sites. PLoS One (2011) 1.04
Targeting the brain with PEG-PLGA nanoparticles modified with phage-displayed peptides. Biomaterials (2011) 1.04
Helicobacter pylori VacA disrupts apical membrane-cytoskeletal interactions in gastric parietal cells. J Biol Chem (2008) 1.04
Polarized distribution of IQGAP proteins in gastric parietal cells and their roles in regulated epithelial cell secretion. Mol Biol Cell (2003) 1.03
The structure of the FANCM-MHF complex reveals physical features for functional assembly. Nat Commun (2012) 1.03
Syntaxin 3 is required for cAMP-induced acid secretion: streptolysin O-permeabilized gastric gland model. Am J Physiol Gastrointest Liver Physiol (2002) 1.03
GPS-PUP: computational prediction of pupylation sites in prokaryotic proteins. Mol Biosyst (2011) 1.01
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Differential secretome analysis reveals CST6 as a suppressor of breast cancer bone metastasis. Cell Res (2012) 1.00