Published in J Biol Chem on November 07, 2001
Rolling cell adhesion. Annu Rev Cell Dev Biol (2010) 1.97
The structure of the GPIb-filamin A complex. Blood (2005) 1.83
FlnA-null megakaryocytes prematurely release large and fragile platelets that circulate poorly. Blood (2011) 1.72
A new form of macrothrombocytopenia induced by a germ-line mutation in the PRKACG gene. Blood (2014) 1.59
A novel interaction between FlnA and Syk regulates platelet ITAM-mediated receptor signaling and function. J Exp Med (2010) 1.45
GPIbα regulates platelet size by controlling the subcellular localization of filamin. Blood (2011) 1.45
Glycoprotein Ibalpha forms disulfide bonds with 2 glycoprotein Ibbeta subunits in the resting platelet. Blood (2006) 1.39
A critical role for 14-3-3zeta protein in regulating the VWF binding function of platelet glycoprotein Ib-IX and its therapeutic implications. Blood (2005) 1.20
Specific heteromeric association of four transmembrane peptides derived from platelet glycoprotein Ib-IX complex. J Mol Biol (2008) 1.02
Identification of a unique filamin A binding region within the cytoplasmic domain of glycoprotein Ibalpha. Biochem J (2005) 0.98
Intrinsic impaired proplatelet formation and microtubule coil assembly of megakaryocytes in a mouse model of Bernard-Soulier syndrome. Haematologica (2009) 0.89
Improved platelet survival after cold storage by prevention of glycoprotein Ibα clustering in lipid rafts. Haematologica (2012) 0.86
iTRAQ proteomic identification of pVHL-dependent and -independent targets of Egln1 prolyl hydroxylase knockdown in renal carcinoma cells. Adv Enzyme Regul (2008) 0.83
A novel structural unit in the N-terminal region of filamins. J Biol Chem (2014) 0.81
Binding of pro-prion to filamin A: by design or an unfortunate blunder. Oncogene (2010) 0.78
Role of 14-3-3ζ in platelet glycoprotein Ibα-von Willebrand factor interaction-induced signaling. Int J Mol Sci (2012) 0.76
Platelet functional alterations in a Bernard-Soulier syndrome patient with filamin A mutation. J Hematol Oncol (2015) 0.75
Membrane skeleton orchestrates the platelet glycoprotein (GP) Ib-IX complex clustering and signaling. IUBMB Life (2016) 0.75
PI 3-kinase p110beta: a new target for antithrombotic therapy. Nat Med (2005) 3.96
A shear gradient-dependent platelet aggregation mechanism drives thrombus formation. Nat Med (2009) 3.57
Warfarin reversal: consensus guidelines, on behalf of the Australasian Society of Thrombosis and Haemostasis. Med J Aust (2004) 2.74
Sequential activation of class IB and class IA PI3K is important for the primed respiratory burst of human but not murine neutrophils. Blood (2005) 2.35
Identification of a fibrin-independent platelet contractile mechanism regulating primary hemostasis and thrombus growth. Blood (2008) 1.82
High shear-dependent loss of membrane integrity and defective platelet adhesion following disruption of the GPIbα-filamin interaction. Blood (2010) 1.75
Evidence for functional redundancy of class IA PI3K isoforms in insulin signalling. Biochem J (2007) 1.74
Two distinct pathways regulate platelet phosphatidylserine exposure and procoagulant function. Blood (2009) 1.74
Caspase-9 mediates the apoptotic death of megakaryocytes and platelets, but is dispensable for their generation and function. Blood (2012) 1.67
Identification of a 2-stage platelet aggregation process mediating shear-dependent thrombus formation. Blood (2006) 1.63
Bcl-xL-inhibitory BH3 mimetics can induce a transient thrombocytopathy that undermines the hemostatic function of platelets. Blood (2011) 1.56
Shear-dependent tether formation during platelet translocation on von Willebrand factor. Blood (2002) 1.42
Intercellular calcium communication regulates platelet aggregation and thrombus growth. J Cell Biol (2003) 1.42
Reconstituted high-density lipoprotein attenuates platelet function in individuals with type 2 diabetes mellitus by promoting cholesterol efflux. Circulation (2009) 1.40
Thrombin overcomes the thrombosis defect associated with platelet GPVI/FcRgamma deficiency. Blood (2006) 1.37
The role of platelets in atherothrombosis. Hematology Am Soc Hematol Educ Program (2011) 1.34
Targeting the PI3K p110alpha isoform inhibits medulloblastoma proliferation, chemoresistance, and migration. Clin Cancer Res (2008) 1.30
SHIP1 and Lyn Kinase Negatively Regulate Integrin alpha IIb beta 3 signaling in platelets. J Biol Chem (2004) 1.25
Signaling role for phospholipase C gamma 2 in platelet glycoprotein Ib alpha calcium flux and cytoskeletal reorganization. Involvement of a pathway distinct from FcR gamma chain and Fc gamma RIIA. J Biol Chem (2003) 1.24
Distinct glycoprotein Ib/V/IX and integrin alpha IIbbeta 3-dependent calcium signals cooperatively regulate platelet adhesion under flow. J Biol Chem (2001) 1.23
Continuous signaling via PI3K isoforms beta and gamma is required for platelet ADP receptor function in dynamic thrombus stabilization. Blood (2006) 1.21
Importance of platelet phospholipase Cgamma2 signaling in arterial thrombosis as a function of lesion severity. Arterioscler Thromb Vasc Biol (2005) 1.20
A microfluidics device to monitor platelet aggregation dynamics in response to strain rate micro-gradients in flowing blood. Lab Chip (2009) 1.16
Novel role of platelets in mediating inflammatory responses and ventricular rupture or remodeling following myocardial infarction. Arterioscler Thromb Vasc Biol (2011) 1.15
Integrin alpha IIb beta 3-dependent calcium signals regulate platelet-fibrinogen interactions under flow. Involvement of phospholipase C gamma 2. J Biol Chem (2003) 1.13
Role of phosphoinositide 3-kinase beta in glycoprotein VI-mediated Akt activation in platelets. J Biol Chem (2009) 1.11
Erythrocyte hemolysis and hemoglobin oxidation promote ferric chloride-induced vascular injury. J Biol Chem (2009) 1.10
Essential role for phosphoinositide 3-kinase in shear-dependent signaling between platelet glycoprotein Ib/V/IX and integrin alpha(IIb)beta(3). Blood (2002) 1.09
Pathophysiological levels of soluble P-selectin mediate adhesion of leukocytes to the endothelium through Mac-1 activation. Circ Res (2008) 1.08
Multiple alterations of platelet functions dominated by increased secretion in mice lacking Cdc42 in platelets. Blood (2010) 1.07
Platelet factor XIII and calpain negatively regulate integrin alphaIIbbeta3 adhesive function and thrombus growth. J Biol Chem (2004) 1.04
A mechanistic model for paradoxical platelet activation by ligand-mimetic alphaIIb beta3 (GPIIb/IIIa) antagonists. Arterioscler Thromb Vasc Biol (2006) 1.04
Identification of a unique co-operative phosphoinositide 3-kinase signaling mechanism regulating integrin alpha IIb beta 3 adhesive function in platelets. J Biol Chem (2007) 1.04
The CXCR1/2 ligand NAP-2 promotes directed intravascular leukocyte migration through platelet thrombi. Blood (2013) 1.03
Leucine-rich repeats 2-4 (Leu60-Glu128) of platelet glycoprotein Ibalpha regulate shear-dependent cell adhesion to von Willebrand factor. J Biol Chem (2006) 1.03
RhoA sustains integrin alpha IIbbeta 3 adhesion contacts under high shear. J Biol Chem (2002) 1.01
Shear induces a unique series of morphological changes in translocating platelets: effects of morphology on translocation dynamics. Arterioscler Thromb Vasc Biol (2005) 1.01
The impact of blood rheology on the molecular and cellular events underlying arterial thrombosis. J Mol Med (Berl) (2006) 1.01
New insights into the haemostatic function of platelets. Br J Haematol (2009) 1.01
Identification of a novel 14-3-3zeta binding site within the cytoplasmic tail of platelet glycoprotein Ibalpha. Blood (2004) 0.99
Class I phosphoinositide 3-kinases. Int J Biochem Cell Biol (2003) 0.99
Phosphatidylinositol(4,5)bisphosphate coordinates actin-mediated mobilization and translocation of secretory vesicles to the plasma membrane of chromaffin cells. Nat Commun (2011) 0.99
Identification of a unique filamin A binding region within the cytoplasmic domain of glycoprotein Ibalpha. Biochem J (2005) 0.98
Spectrum of the mutations in Bernard-Soulier syndrome. Hum Mutat (2014) 0.97
Novel role for insulin as an autocrine growth factor for malignant brain tumour cells. Biochem J (2007) 0.97
A sensitized RNA interference screen identifies a novel role for the PI3K p110γ isoform in medulloblastoma cell proliferation and chemoresistance. Mol Cancer Res (2011) 0.96
Bcl-xL-inhibitory BH3 mimetics (ABT-737 or ABT-263) and the modulation of cytosolic calcium flux and platelet function. Blood (2012) 0.95
A critical role for the transcription factor Scl in platelet production during stress thrombopoiesis. Blood (2006) 0.94
PI3-kinase p110α mediates β1 integrin-induced Akt activation and membrane protrusion during cell attachment and initial spreading. Cell Signal (2010) 0.94
Dissecting isoform selectivity of PI3K inhibitors: the role of non-conserved residues in the catalytic pocket. Biochem J (2008) 0.94
Phosphoinositide 3-kinase p110 beta regulates integrin alpha IIb beta 3 avidity and the cellular transmission of contractile forces. J Biol Chem (2009) 0.92
New consistent QTL in pea associated with partial resistance to Aphanomyces euteiches in multiple French and American environments. Theor Appl Genet (2011) 0.92
Non-redundant roles of phosphoinositide 3-kinase isoforms alpha and beta in glycoprotein VI-induced platelet signaling and thrombus formation. J Biol Chem (2009) 0.92
Insulin-like growth factor-1 regulates platelet activation through PI3-Kalpha isoform. Blood (2007) 0.90
Reconstitution of the platelet glycoprotein Ib-IX complex in phospholipid bilayer Nanodiscs. Biochemistry (2011) 0.89
Role of the intracellular domains of GPIb in controlling the adhesive properties of the platelet GPIb/V/IX complex. Blood (2003) 0.89
Conversion of platelets from a proaggregatory to a proinflammatory adhesive phenotype: role of PAF in spatially regulating neutrophil adhesion and spreading. Blood (2007) 0.89
Importance of temporal flow gradients and integrin alphaIIbbeta3 mechanotransduction for shear activation of platelets. J Biol Chem (2005) 0.89
QTL meta-analysis provides a comprehensive view of loci controlling partial resistance to Aphanomyces euteiches in four sources of resistance in pea. BMC Plant Biol (2013) 0.88
Techniques to examine platelet adhesive interactions under flow. Methods Mol Biol (2004) 0.88
Generation and characterization of mice with null mutation of the chloride intracellular channel 1 gene. Genesis (2010) 0.88
Diverging signaling events control the pathway of GPVI down-regulation in vivo. Blood (2007) 0.88
Synthesis, biological evaluation and molecular modelling of sulfonohydrazides as selective PI3K p110alpha inhibitors. Bioorg Med Chem (2007) 0.87
Pathologic shear triggers shedding of vascular receptors: a novel mechanism for down-regulation of platelet glycoprotein VI in stenosed coronary vessels. Blood (2012) 0.87
Platelet recruitment to the inflamed glomerulus occurs via an alphaIIbbeta3/GPVI-dependent pathway. Am J Pathol (2010) 0.86
Bidirectional integrin alphaIIbbeta3 signalling regulating platelet adhesion under flow: contribution of protein kinase C. Biochem J (2003) 0.86
An investigation on platelet transport during thrombus formation at micro-scale stenosis. PLoS One (2013) 0.86
Targeting platelet GPIbβ reduces platelet adhesion, GPIb signaling and thrombin generation and prevents arterial thrombosis. Arterioscler Thromb Vasc Biol (2013) 0.83
A synthetic haemoglobin-based oxygen carrier and the reversal of cardiac hypoxia secondary to severe anaemia following trauma. Med J Aust (2011) 0.83