Published in Neoplasia on June 01, 2005
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Identification and targeting of cancer stem cells. Bioessays (2009) 1.44
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Telomerase and the aging process. Exp Gerontol (2007) 0.89
Fibroblast stimulation of blood vessel development and cancer cell invasion in a subrenal capsule xenograft model: stress-induced premature senescence does not increase effect. Neoplasia (2007) 0.88
Improving cell therapy--experiments using transplanted telomerase-immortalized cells in immunodeficient mice. Mech Ageing Dev (2006) 0.86
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Modelling the molecular circuitry of cancer. Nat Rev Cancer (2002) 5.43
Enumeration of the simian virus 40 early region elements necessary for human cell transformation. Mol Cell Biol (2002) 4.77
Distinct requirements for Ras oncogenesis in human versus mouse cells. Genes Dev (2002) 4.30
Immortalization and transformation of primary human airway epithelial cells by gene transfer. Oncogene (2002) 3.80
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The tumor-suppressive functions of the human INK4A locus. Cancer Cell (2003) 2.31
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Human adrenocortical cell xenotransplantation: model of cotransplantation of human adrenocortical cells and 3T3 cells in scid mice to form vascularized functional tissue and prevent adrenal insufficiency. Xenotransplantation (2002) 0.95
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Mutational analysis defines a minimum level of telomerase activity required for tumourigenic growth of human cells. Oncogene (2002) 0.84
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Senescent human fibroblasts increase the early growth of xenograft tumors via matrix metalloproteinase secretion. Cancer Res (2007) 2.94
DNA end joining becomes less efficient and more error-prone during cellular senescence. Proc Natl Acad Sci U S A (2004) 2.51
Dynamic assembly of chromatin complexes during cellular senescence: implications for the growth arrest of human melanocytic nevi. Aging Cell (2007) 2.07
Resistance to experimental tumorigenesis in cells of a long-lived mammal, the naked mole-rat (Heterocephalus glaber). Aging Cell (2010) 1.69
Competition of CUGBP1 and calreticulin for the regulation of p21 translation determines cell fate. EMBO J (2004) 1.54
Expression of human telomerase (hTERT) does not prevent stress-induced senescence in normal human fibroblasts but protects the cells from stress-induced apoptosis and necrosis. J Biol Chem (2002) 1.50
MRG15, a novel chromodomain protein, is present in two distinct multiprotein complexes involved in transcriptional activation. J Biol Chem (2002) 1.44
p53 is preferentially recruited to the promoters of growth arrest genes p21 and GADD45 during replicative senescence of normal human fibroblasts. Cancer Res (2006) 1.43
Upregulation of mortalin/mthsp70/Grp75 contributes to human carcinogenesis. Int J Cancer (2006) 1.42
MRG15 regulates embryonic development and cell proliferation. Mol Cell Biol (2005) 1.35
Generation of induced pluripotent stem cells from newborn marmoset skin fibroblasts. Stem Cell Res (2010) 1.31
Microfluidics device for single cell gene expression analysis in Saccharomyces cerevisiae. Yeast (2006) 1.16
Primary and compensatory roles for RB family members at cell cycle gene promoters that are deacetylated and downregulated in doxorubicin-induced senescence of breast cancer cells. Mol Cell Biol (2006) 1.16
Mrg15 null and heterozygous mouse embryonic fibroblasts exhibit DNA-repair defects post exposure to gamma ionizing radiation. FEBS Lett (2007) 1.11
Adenoviral vectors can impair adrenocortical steroidogenesis: clinical implications for natural infections and gene therapy. Proc Natl Acad Sci U S A (2002) 1.10
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Role of IFI 16 in cellular senescence of human fibroblasts. Oncogene (2004) 1.07
WNT4 acts downstream of BMP2 and functions via β-catenin signaling pathway to regulate human endometrial stromal cell differentiation. Endocrinology (2012) 1.07
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Stress resistance in the naked mole-rat: the bare essentials - a mini-review. Gerontology (2012) 1.03
Improved coinfection with amphotropic pseudotyped retroviral vectors. J Biomed Biotechnol (2009) 1.02
Progressive loss of malignant behavior in telomerase-negative tumorigenic adrenocortical cells and restoration of tumorigenicity by human telomerase reverse transcriptase. Cancer Res (2004) 0.99
Establishment and characterization of a cancer cell line derived from an aggressive childhood liver tumor. Pediatr Blood Cancer (2009) 0.98
Evidence that high telomerase activity may induce a senescent-like growth arrest in human fibroblasts. J Biol Chem (2002) 0.97
Human adrenocortical cell xenotransplantation: model of cotransplantation of human adrenocortical cells and 3T3 cells in scid mice to form vascularized functional tissue and prevent adrenal insufficiency. Xenotransplantation (2002) 0.95
Type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3) contributes to testosterone production in the adrenal reticularis. J Clin Endocrinol Metab (2009) 0.95
MRG15, a component of HAT and HDAC complexes, is essential for proliferation and differentiation of neural precursor cells. J Neurosci Res (2009) 0.94
Multipurpose MRG domain involved in cell senescence and proliferation exhibits structural homology to a DNA-interacting domain. Structure (2006) 0.94
Mortalin: present and prospective. Exp Gerontol (2002) 0.92
The genomic organization, promoter position and expression profile of the mouse MRG15 gene. Gene (2002) 0.92
The role of the MORF/MRG family of genes in cell growth, differentiation, DNA repair, and thereby aging. Ann N Y Acad Sci (2007) 0.92
Global gene expression response to telomerase in bovine adrenocortical cells. Biochem Biophys Res Commun (2005) 0.91
Nonhuman primate induced pluripotent stem cells in regenerative medicine. Stem Cells Int (2012) 0.91
MRGX is a novel transcriptional regulator that exhibits activation or repression of the B-myb promoter in a cell type-dependent manner. J Biol Chem (2003) 0.90
Identification of alpha-enolase as a nuclear DNA-binding protein in the zona fasciculata but not the zona reticularis of the human adrenal cortex. J Endocrinol (2005) 0.89
Fibroblast stimulation of blood vessel development and cancer cell invasion in a subrenal capsule xenograft model: stress-induced premature senescence does not increase effect. Neoplasia (2007) 0.88
Improving cell therapy--experiments using transplanted telomerase-immortalized cells in immunodeficient mice. Mech Ageing Dev (2006) 0.86
Functional analysis of MRG-1: the ortholog of human MRG15 in Caenorhabditis elegans. J Gerontol A Biol Sci Med Sci (2005) 0.85
Emerging role of the MORF/MRG gene family in various biological processes, including aging. Ann N Y Acad Sci (2010) 0.85
PAM14, a novel MRG- and Rb-associated protein, is not required for development and T-cell function in mice. Mol Cell Biol (2004) 0.85
Adrenocortical cell transplantation in scid mice: the role of the host animals' adrenal glands. J Steroid Biochem Mol Biol (2003) 0.84
Immortal ALT+ human cells do not require telomerase reverse transcriptase for malignant transformation. Cancer Res (2005) 0.83
MrgX is not essential for cell growth and development in the mouse. Mol Cell Biol (2005) 0.82
Cooperation of hTERT, SV40 T antigen and oncogenic Ras in tumorigenesis: a cell transplantation model using bovine adrenocortical cells. Neoplasia (2002) 0.82
Screen anticancer drug in vitro using resonance light scattering technique. Talanta (2008) 0.82
What can we learn from gene expression profiling for adrenal tumor management? J Clin Endocrinol Metab (2005) 0.82
The cell senescence inducing gene product MORF4 is regulated by degradation via the ubiquitin/proteasome pathway. Exp Cell Res (2009) 0.82
MRG15 activates the cdc2 promoter via histone acetylation in human cells. Exp Cell Res (2011) 0.82
Loss of the chromatin regulator MRG15 limits neural stem/progenitor cell proliferation via increased expression of the p21 Cdk inhibitor. Stem Cell Res (2011) 0.81
Conditional inactivation of MRG15 gene function limits survival during larval and adult stages of Drosophila melanogaster. Exp Gerontol (2010) 0.81
In vitro osteogenic differentiation of adipose stem cells after lentiviral transduction with green fluorescent protein. J Craniofac Surg (2009) 0.81
New methods for investigating experimental human adrenal tumorigenesis. Mol Cell Endocrinol (2008) 0.81
Directed neural differentiation of induced pluripotent stem cells from non-human primates. Exp Biol Med (Maywood) (2013) 0.81
Neoplastic conversion of human colon smooth muscle cells: No requirement for telomerase. Mol Carcinog (2008) 0.81
The aging factor in health and disease: the promise of basic research on aging. Aging Clin Exp Res (2004) 0.81
Antitumor function and mechanism of phycoerythrin from Porphyra haitanensis. Biol Res (2013) 0.80
The hypoglycemic effect of a polysaccharide (GLP) from Gracilaria lemaneiformis and its degradation products in diabetic mice. Food Funct (2015) 0.80
Replicative senescence of human and mouse cells in culture: significance for aging research. Mech Ageing Dev (2003) 0.80
Exploring the link between MORF4L1 and risk of breast cancer. Breast Cancer Res (2011) 0.79
Optimizing orthotopic cell transplantation in the mouse adrenal gland. Cell Transplant (2010) 0.79
Using cell transplantation to investigate genes involved in aging. Mech Ageing Dev (2003) 0.77
Intradermal cell transplantation in soluble collagen. Cell Transplant (2002) 0.77
Hedgehog-signaling is upregulated in non-producing human adrenal adenomas and antagonism of hedgehog-signaling inhibits proliferation of NCI-H295R cells and an immortalized primary human adrenal cell line. J Steroid Biochem Mol Biol (2013) 0.76
A single-stage mechanism controls replicative senescence through Sudden Senescence Syndrome. Biogerontology (2002) 0.76
Bioluminescence measurements in mice using a skin window. J Biomed Opt (2007) 0.76
Effect and mechanism of Salicornia bigelovii Torr. plant salt on blood pressure in SD rats. Food Funct (2015) 0.76
Tumorigenic study on hepatocytes coexpressing SV40 with Ras. Mol Carcinog (2006) 0.76
Derivation of induced pluripotent stem cells from the baboon: a nonhuman primate model for preclinical testing of stem cell therapies. Cell Reprogram (2013) 0.75
Longitudinal analysis of short-term high-fat diet on endothelial senescence in baboons. Am J Cardiovasc Dis (2013) 0.75
Telomerase is not required for experimental tumorigenesis of human and bovine adrenocortical cells. Endocr Res (2004) 0.75
The role of chromatin reorganization in the process of cellular senescence. Curr Drug Targets (2012) 0.75
Fibroblasts from Werner syndrome patients: cancer cells derived by experimental introduction of oncogenes maintain malignant properties despite entering crisis. Oncol Rep (2010) 0.75
Use of Gemini surfactant in a one-step ellagic acid assay by resonance light scattering technique. Talanta (2010) 0.75
An interview with Peter J. Hornsby, Ph.D. Interview by Vicki Glaser. J Anti Aging Med (2003) 0.75
Early-senescing human skin fibroblasts do not demonstrate accelerated telomere shortening. J Gerontol A Biol Sci Med Sci (2005) 0.75
Biosensor technology in aging research and age-related diseases. Ageing Res Rev (2011) 0.75
Human chorionic gonadotropin does not alter patterns of adrenal androgen secretion in primary human adrenal reticularis and fasciculata cell culture. Menopause (2007) 0.75