PubRank

Donald F Hunt

Author PubWeight™ 261.36‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Peptide and protein sequence analysis by electron transfer dissociation mass spectrometry. Proc Natl Acad Sci U S A 2004 13.14
2 Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae. Nat Biotechnol 2002 8.37
3 Histone methyltransferases direct different degrees of methylation to define distinct chromatin domains. Mol Cell 2003 6.44
4 Regulation of HP1-chromatin binding by histone H3 methylation and phosphorylation. Nature 2005 6.40
5 A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis. Nature 2002 6.19
6 Set2 is a nucleosomal histone H3-selective methyltransferase that mediates transcriptional repression. Mol Cell Biol 2002 5.42
7 Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry. Proc Natl Acad Sci U S A 2007 5.09
8 Novel linear quadrupole ion trap/FT mass spectrometer: performance characterization and use in the comparative analysis of histone H3 post-translational modifications. J Proteome Res 2004 4.32
9 Aurora B phosphorylates centromeric MCAK and regulates its localization and microtubule depolymerization activity. Curr Biol 2004 4.20
10 Organismal differences in post-translational modifications in histones H3 and H4. J Biol Chem 2006 3.84
11 Chemical derivatization of histones for facilitated analysis by mass spectrometry. Nat Protoc 2007 3.78
12 Gene silencing: trans-histone regulatory pathway in chromatin. Nature 2002 3.77
13 Protein identification using sequential ion/ion reactions and tandem mass spectrometry. Proc Natl Acad Sci U S A 2005 3.77
14 Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes. Proc Natl Acad Sci U S A 2003 3.75
15 Cathepsin L proteolytically processes histone H3 during mouse embryonic stem cell differentiation. Cell 2008 3.09
16 A neutral loss activation method for improved phosphopeptide sequence analysis by quadrupole ion trap mass spectrometry. Anal Chem 2004 3.08
17 Expression patterns and post-translational modifications associated with mammalian histone H3 variants. J Biol Chem 2005 3.00
18 The utility of ETD mass spectrometry in proteomic analysis. Biochim Biophys Acta 2006 2.85
19 Extensive crosstalk between O-GlcNAcylation and phosphorylation regulates cytokinesis. Sci Signal 2010 2.79
20 MAPKAP kinase 2 phosphorylates tristetraprolin on in vivo sites including Ser178, a site required for 14-3-3 binding. J Biol Chem 2003 2.53
21 Long-distance combinatorial linkage between methylation and acetylation on histone H3 N termini. Proc Natl Acad Sci U S A 2007 2.43
22 N-terminal alpha-methylation of RCC1 is necessary for stable chromatin association and normal mitosis. Nat Cell Biol 2007 2.36
23 Insulin controls subcellular localization and multisite phosphorylation of the phosphatidic acid phosphatase, lipin 1. J Biol Chem 2006 2.32
24 The vertebrate Ndc80 complex contains Spc24 and Spc25 homologs, which are required to establish and maintain kinetochore-microtubule attachment. Curr Biol 2004 2.31
25 Mass spectrometry analysis of Arabidopsis histone H3 reveals distinct combinations of post-translational modifications. Nucleic Acids Res 2004 2.28
26 O-GlcNAc regulates FoxO activation in response to glucose. J Biol Chem 2008 2.27
27 Electron transfer dissociation of peptide anions. J Am Soc Mass Spectrom 2005 2.26
28 RNAi-dependent H3K27 methylation is required for heterochromatin formation and DNA elimination in Tetrahymena. Genes Dev 2007 2.26
29 Saccharomyces cerevisiae Rad9 acts as a Mec1 adaptor to allow Rad53 activation. Curr Biol 2005 2.20
30 Androgen receptor phosphorylation. Regulation and identification of the phosphorylation sites. J Biol Chem 2002 2.01
31 Genomic and functional evolution of the Drosophila melanogaster sperm proteome. Nat Genet 2006 1.97
32 Phosphoproteome analysis of capacitated human sperm. Evidence of tyrosine phosphorylation of a kinase-anchoring protein 3 and valosin-containing protein/p97 during capacitation. J Biol Chem 2002 1.96
33 NRMT is an alpha-N-methyltransferase that methylates RCC1 and retinoblastoma protein. Nature 2010 1.95
34 Characterization of histones and their post-translational modifications by mass spectrometry. Curr Opin Chem Biol 2006 1.92
35 Serine 31 phosphorylation of histone variant H3.3 is specific to regions bordering centromeres in metaphase chromosomes. Proc Natl Acad Sci U S A 2005 1.91
36 Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire. Proc Natl Acad Sci U S A 2012 1.89
37 Methods for analyzing peptides and proteins on a chromatographic timescale by electron-transfer dissociation mass spectrometry. Nat Protoc 2008 1.87
38 Par3 controls epithelial spindle orientation by aPKC-mediated phosphorylation of apical Pins. Curr Biol 2010 1.86
39 Post-acquisition ETD spectral processing for increased peptide identifications. J Am Soc Mass Spectrom 2009 1.86
40 Proteome-wide prediction of acetylation substrates. Proc Natl Acad Sci U S A 2009 1.81
41 A PGC-1alpha-O-GlcNAc transferase complex regulates FoxO transcription factor activity in response to glucose. J Biol Chem 2008 1.76
42 Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets. Proc Natl Acad Sci U S A 2012 1.75
43 Enrichment and site mapping of O-linked N-acetylglucosamine by a combination of chemical/enzymatic tagging, photochemical cleavage, and electron transfer dissociation mass spectrometry. Mol Cell Proteomics 2009 1.72
44 A novel histone deacetylase pathway regulates mitosis by modulating Aurora B kinase activity. Genes Dev 2006 1.70
45 Tandem mass spectrometry for peptide and protein sequence analysis. Biotechniques 2005 1.70
46 Codependent functions of RSK2 and the apoptosis-promoting factor TIA-1 in stress granule assembly and cell survival. Mol Cell 2008 1.67
47 Use of differential isotopic labeling and mass spectrometry to analyze capacitation-associated changes in the phosphorylation status of mouse sperm proteins. J Proteome Res 2009 1.64
48 Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes. J Proteome Res 2006 1.63
49 Toward a protein profile of Escherichia coli: comparison to its transcription profile. Proc Natl Acad Sci U S A 2003 1.60
50 Analysis of intact proteins on a chromatographic time scale by electron transfer dissociation tandem mass spectrometry. Int J Mass Spectrom 2007 1.56
51 Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex. EMBO J 2007 1.55
52 mTOR-dependent stimulation of the association of eIF4G and eIF3 by insulin. EMBO J 2006 1.51
53 Identification of histone H3 lysine 36 acetylation as a highly conserved histone modification. J Biol Chem 2006 1.50
54 The enhancement of histone H4 and H2A serine 1 phosphorylation during mitosis and S-phase is evolutionarily conserved. Chromosoma 2004 1.47
55 The platelet microparticle proteome. J Proteome Res 2005 1.42
56 Resetting the epigenetic histone code in the MRL-lpr/lpr mouse model of lupus by histone deacetylase inhibition. J Proteome Res 2005 1.41
57 Pillars article: Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry. Science 1992. 255: 1261-1263. J Immunol 2007 1.39
58 RLIP76 (RalBP1) is an R-Ras effector that mediates adhesion-dependent Rac activation and cell migration. J Cell Biol 2006 1.38
59 Methods for the detection of paxillin post-translational modifications and interacting proteins by mass spectrometry. J Proteome Res 2005 1.38
60 CDK9 regulates AR promoter selectivity and cell growth through serine 81 phosphorylation. Mol Endocrinol 2010 1.35
61 Analysis of protein phosphorylation by mass spectrometry. Methods 2005 1.33
62 Characterization of phosphorylation sites on histone H1 isoforms by tandem mass spectrometry. J Proteome Res 2004 1.33
63 Identification of class I MHC-associated phosphopeptides as targets for cancer immunotherapy. Proc Natl Acad Sci U S A 2006 1.32
64 Proteomic analysis of early melanosomes: identification of novel melanosomal proteins. J Proteome Res 2003 1.31
65 Pathways mediating the nuclear import of histones H3 and H4 in yeast. J Biol Chem 2001 1.31
66 Posttranslational modification of CENP-A influences the conformation of centromeric chromatin. Proc Natl Acad Sci U S A 2013 1.30
67 Modifications of human histone H3 variants during mitosis. Biochemistry 2005 1.29
68 Anopheles gambiae genome reannotation through synthesis of ab initio and comparative gene prediction algorithms. Genome Biol 2006 1.27
69 Analysis of histones in Xenopus laevis. I. A distinct index of enriched variants and modifications exists in each cell type and is remodeled during developmental transitions. J Biol Chem 2008 1.26
70 Comprehensive phosphoprotein analysis of linker histone H1 from Tetrahymena thermophila. Mol Cell Proteomics 2006 1.26
71 Structural basis for the presentation of tumor-associated MHC class II-restricted phosphopeptides to CD4+ T cells. J Mol Biol 2010 1.26
72 A receptor for activated C kinase is part of messenger ribonucleoprotein complexes associated with polyA-mRNAs in neurons. J Neurosci 2002 1.25
73 Sorting of Pmel17 to melanosomes through the plasma membrane by AP1 and AP2: evidence for the polarized nature of melanocytes. J Cell Sci 2006 1.20
74 Talin phosphorylation sites mapped by mass spectrometry. J Cell Sci 2005 1.19
75 Identification of tumor-associated, MHC class II-restricted phosphopeptides as targets for immunotherapy. Proc Natl Acad Sci U S A 2009 1.19
76 Tapasin is a facilitator, not an editor, of class I MHC peptide binding. J Immunol 2003 1.19
77 The minor histocompatibility antigen HA-3 arises from differential proteasome-mediated cleavage of the lymphoid blast crisis (Lbc) oncoprotein. Blood 2003 1.18
78 Paxillin phosphorylation sites mapped by mass spectrometry. J Cell Sci 2005 1.18
79 The PANE1 gene encodes a novel human minor histocompatibility antigen that is selectively expressed in B-lymphoid cells and B-CLL. Blood 2006 1.17
80 Acetylation of vertebrate H2A.Z and its effect on the structure of the nucleosome. Biochemistry 2009 1.17
81 Characterization of the histone H2A.Z-1 and H2A.Z-2 isoforms in vertebrates. BMC Biol 2009 1.17
82 Analysis of MHC class II antigen processing by quantitation of peptides that constitute nested sets. J Immunol 2002 1.16
83 Analysis of proteins and peptides on a chromatographic timescale by electron-transfer dissociation MS. FEBS J 2007 1.14
84 Proteomic, microarray, and signature-tagged mutagenesis analyses of anaerobic Pseudomonas aeruginosa at pH 6.5, likely representing chronic, late-stage cystic fibrosis airway conditions. J Bacteriol 2008 1.13
85 TAB4 stimulates TAK1-TAB1 phosphorylation and binds polyubiquitin to direct signaling to NF-kappaB. J Biol Chem 2008 1.13
86 Simian virus 40 small t antigen mediates conformation-dependent transfer of protein phosphatase 2A onto the androgen receptor. Mol Cell Biol 2005 1.13
87 MHC class I-associated phosphopeptides are the targets of memory-like immunity in leukemia. Sci Transl Med 2013 1.13
88 Identification of yin-yang regulators and a phosphorylation consensus for male germ cell-associated kinase (MAK)-related kinase. Mol Cell Biol 2006 1.12
89 Analysis of histones in Xenopus laevis. II. mass spectrometry reveals an index of cell type-specific modifications on H3 and H4. J Biol Chem 2008 1.12
90 Phosphorylation-dependent interaction between antigenic peptides and MHC class I: a molecular basis for the presentation of transformed self. Nat Immunol 2008 1.11
91 Cross-talk between two essential nutrient-sensitive enzymes: O-GlcNAc transferase (OGT) and AMP-activated protein kinase (AMPK). J Biol Chem 2014 1.09
92 Front-end electron transfer dissociation: a new ionization source. Anal Chem 2013 1.09
93 Gas channels for NH(3): proteins from hyperthermophiles complement an Escherichia coli mutant. J Bacteriol 2002 1.08
94 Cortactin phosphorylation sites mapped by mass spectrometry. J Cell Sci 2006 1.08
95 Histone H3 Thr 45 phosphorylation is a replication-associated post-translational modification in S. cerevisiae. Nat Cell Biol 2010 1.07
96 A phosphorylated subpopulation of the histone variant macroH2A1 is excluded from the inactive X chromosome and enriched during mitosis. Proc Natl Acad Sci U S A 2008 1.07
97 Trk activation of the ERK1/2 kinase pathway stimulates intermediate chain phosphorylation and recruits cytoplasmic dynein to signaling endosomes for retrograde axonal transport. J Neurosci 2012 1.06
98 Substrate specificity of mammalian N-terminal α-amino methyltransferase NRMT. Biochemistry 2012 1.05
99 Activation of a nuclear Cdc2-related kinase within a mitogen-activated protein kinase-like TDY motif by autophosphorylation and cyclin-dependent protein kinase-activating kinase. Mol Cell Biol 2005 1.04
100 A distinct H2A.X isoform is enriched in Xenopus laevis eggs and early embryos and is phosphorylated in the absence of a checkpoint. Proc Natl Acad Sci U S A 2009 1.04
101 Processing of a class I-restricted epitope from tyrosinase requires peptide N-glycanase and the cooperative action of endoplasmic reticulum aminopeptidase 1 and cytosolic proteases. J Immunol 2006 1.03
102 FAK phosphorylation sites mapped by mass spectrometry. J Cell Sci 2005 1.02
103 Comprehensive analysis of phosphorylation sites in Tensin1 reveals regulation by p38MAPK. Mol Cell Proteomics 2010 1.02
104 Use of selected reaction monitoring mass spectrometry for the detection of specific MHC class I peptide antigens on A3 supertype family members. Cancer Immunol Immunother 2004 1.01
105 Genomics, metagenomics and proteomics in biomining microorganisms. Biotechnol Adv 2005 1.01
106 Protein arginine methyltransferase Prmt5-Mep50 methylates histones H2A and H4 and the histone chaperone nucleoplasmin in Xenopus laevis eggs. J Biol Chem 2011 1.00
107 Diversity of aminopeptidases, derived from four lepidopteran gene duplications, and polycalins expressed in the midgut of Helicoverpa armigera: identification of proteins binding the delta-endotoxin, Cry1Ac of Bacillus thuringiensis. Insect Biochem Mol Biol 2008 1.00
108 Identification of the surfactant protein A receptor 210 as the unconventional myosin 18A. J Biol Chem 2005 0.98
109 The Fanconi anemia core complex forms four complexes of different sizes in different subcellular compartments. J Biol Chem 2004 0.97
110 Optimization of electron transfer dissociation via informed selection of reagents and operating parameters. Anal Chem 2012 0.97
111 FANCG is phosphorylated at serines 383 and 387 during mitosis. Mol Cell Biol 2004 0.97
112 Identification of phosphorylation sites in GIT1. J Cell Sci 2006 0.97
113 Novel function of prothymosin alpha as a potent inhibitor of human immunodeficiency virus type 1 gene expression in primary macrophages. J Virol 2006 0.96
114 Negative regulation of LRP6 function by casein kinase I epsilon phosphorylation. J Biol Chem 2006 0.96
115 Periplasmic proteins of the extremophile Acidithiobacillus ferrooxidans: a high throughput proteomics analysis. Mol Cell Proteomics 2007 0.95
116 Preventing the spontaneous modification of an HLA-A2-restricted peptide at an N-terminal glutamine or an internal cysteine residue enhances peptide antigenicity. J Immunother 2004 0.94
117 Competition between two MHC binding registers in a single peptide processed from myelin basic protein influences tolerance and susceptibility to autoimmunity. J Exp Med 2003 0.93
118 Proteomic characterization of messenger ribonucleoprotein complexes bound to nontranslated or translated poly(A) mRNAs in the rat cerebral cortex. J Biol Chem 2004 0.92
119 Binding of function-blocking mAbs to mouse and human P-selectin glycoprotein ligand-1 peptides with and without tyrosine sulfation. J Leukoc Biol 2002 0.91
120 Site-specific casein kinase 1epsilon-dependent phosphorylation of Dishevelled modulates beta-catenin signaling. FEBS J 2006 0.91
121 A novel model to identify interaction partners of the PTEN tumor suppressor gene in human bladder cancer. Biochem Biophys Res Commun 2006 0.91
122 Phosphorylation by casein kinase 2 regulates Nap1 localization and function. Mol Cell Biol 2007 0.89
123 Cytosolic malate dehydrogenase confers selectivity of the nucleic acid-conducting channel. Proc Natl Acad Sci U S A 2002 0.89
124 Distinct orientation of the alloreactive monoclonal CD8 T cell activation program by three different peptide/MHC complexes. Eur J Immunol 2006 0.88
125 O-Linked β-N-acetylglucosamine (O-GlcNAc) regulates emerin binding to barrier to autointegration factor (BAF) in a chromatin- and lamin B-enriched "niche". J Biol Chem 2013 0.88
126 Inhibition of tristetraprolin deadenylation by poly(A) binding protein. Am J Physiol Gastrointest Liver Physiol 2008 0.87
127 An experimentally derived database of candidate Ras-interacting proteins. J Proteome Res 2007 0.86
128 Smac is required for cytochrome c-induced apoptosis in prostate cancer LNCaP cells. Cancer Res 2002 0.86
129 Identification of novel and widely expressed cancer/testis gene isoforms that elicit spontaneous cytotoxic T-lymphocyte reactivity to melanoma. Cancer Res 2004 0.85
130 The characterization of amphibian nucleoplasmins yields new insight into their role in sperm chromatin remodeling. BMC Genomics 2006 0.85
131 Peptide-binding motifs associated with MHC molecules common in Chinese rhesus macaques are analogous to those of human HLA supertypes and include HLA-B27-like alleles. Immunogenetics 2013 0.85
132 Expression of Aedes trypsin-modulating oostatic factor on the virion of TMV: A potential larvicide. Proc Natl Acad Sci U S A 2006 0.85
133 Identification and origin of N-linked β-D-N-acetylglucosamine monosaccharide modifications on Arabidopsis proteins. Plant Physiol 2012 0.85
134 Structure-based design of altered MHC class II-restricted peptide ligands with heterogeneous immunogenicity. J Immunol 2013 0.85
135 C. elegans pur alpha, an activator of end-1, synergizes with the Wnt pathway to specify endoderm. Dev Biol 2008 0.84
136 Proteomic analysis and identification of the structural and regulatory proteins of the Rhodobacter capsulatus gene transfer agent. J Proteome Res 2009 0.84
137 Nuclear import of TFIIB is mediated by Kap114p, a karyopherin with multiple cargo-binding domains. Mol Biol Cell 2005 0.84
138 HDM2-binding partners: interaction with translation elongation factor EF1alpha. J Proteome Res 2007 0.84
139 Mass spectrometric identification of phosphorylation sites of rRNA transcription factor upstream binding factor. Am J Physiol Cell Physiol 2006 0.83
140 Protein profile of osteoarthritic human articular cartilage using tandem mass spectrometry. Rapid Commun Mass Spectrom 2006 0.83
141 C-terminal phosphorylation of murine testis-specific histone H1t in elongating spermatids. J Proteome Res 2008 0.82
142 Site-specific phosphorylation of the DNA damage response mediator rad9 by cyclin-dependent kinases regulates activation of checkpoint kinase 1. PLoS Genet 2013 0.81
143 Identification of phosphorylation sites in betaPIX and PAK1. J Cell Sci 2007 0.81
144 Increasing peptide identifications and decreasing search times for ETD spectra by pre-processing and calculation of parent precursor charge. Proteome Sci 2012 0.81
145 Intestinal cell kinase (ICK) promotes activation of mTOR complex 1 (mTORC1) through phosphorylation of Raptor Thr-908. J Biol Chem 2012 0.81
146 Identification of a shared epitope recognized by melanoma-specific, HLA-A3-restricted cytotoxic T lymphocytes. Immunol Lett 2003 0.81
147 Identification by mass spectrometry of CD8(+)-T-cell Mycobacterium tuberculosis epitopes within the Rv0341 gene product. Infect Immun 2002 0.80
148 Identification of a 17beta-hydroxysteroid dehydrogenase type 12 pseudogene as the source of a highly restricted BALB/c Meth A tumor rejection peptide. Cancer Immunol Immunother 2009 0.80
149 O-GlcNAcylation of the Plum pox virus capsid protein catalyzed by SECRET AGENT: characterization of O-GlcNAc sites by electron transfer dissociation mass spectrometry. Amino Acids 2010 0.80
150 O-GlcNAc modification of the coat protein of the potyvirus Plum pox virus enhances viral infection. Virology 2013 0.79
151 Impaired assembly results in the accumulation of multiple HLA-C heavy chain folding intermediates. J Immunol 2005 0.79
152 Weak agonist self-peptides promote selection and tuning of virus-specific T cells. Eur J Immunol 2003 0.78
153 Predominant occupation of the class I MHC molecule H-2Kwm7 with a single self-peptide suggests a mechanism for its diabetes-protective effect. Int Immunol 2010 0.77
154 Mitogen-activated protein kinase signaling mediates phosphorylation of polycomb ortholog Cbx7. J Biol Chem 2013 0.77
155 Protein digestion and phosphopeptide enrichment on a glass microchip. Anal Chim Acta 2005 0.76
156 Identification of the peptide-binding motif recognized by the pigtail macaque class I MHC molecule Mane-A1*082:01 (Mane A*0301). Immunogenetics 2012 0.76
157 Bacterial biofilms of importance to medicine and bioterrorism: proteomic techniques to identify novel vaccine components and drug targets. Expert Opin Biol Ther 2003 0.76
158 Identification and Characterization of Complex Glycosylated Peptides Presented by the MHC Class II Processing Pathway in Melanoma. J Proteome Res 2016 0.75