Published in J Biol Chem on December 22, 2008
Cross talk between O-GlcNAcylation and phosphorylation: roles in signaling, transcription, and chronic disease. Annu Rev Biochem (2011) 4.95
From estrogen-centric to aging and oxidative stress: a revised perspective of the pathogenesis of osteoporosis. Endocr Rev (2010) 3.11
Regulation of PGC-1α, a nodal regulator of mitochondrial biogenesis. Am J Clin Nutr (2011) 2.98
FOXOs: signalling integrators for homeostasis maintenance. Nat Rev Mol Cell Biol (2013) 2.83
The hexosamine signaling pathway: O-GlcNAc cycling in feast or famine. Biochim Biophys Acta (2009) 2.66
Chronic rapamycin treatment causes glucose intolerance and hyperlipidemia by upregulating hepatic gluconeogenesis and impairing lipid deposition in adipose tissue. Diabetes (2010) 2.65
O-linked beta-N-acetylglucosamine (O-GlcNAc): Extensive crosstalk with phosphorylation to regulate signaling and transcription in response to nutrients and stress. Biochim Biophys Acta (2009) 2.64
Identification of protein O-GlcNAcylation sites using electron transfer dissociation mass spectrometry on native peptides. Proc Natl Acad Sci U S A (2009) 2.54
The intersections between O-GlcNAcylation and phosphorylation: implications for multiple signaling pathways. J Cell Sci (2010) 2.22
O-GlcNAc signaling: a metabolic link between diabetes and cancer? Trends Biochem Sci (2010) 2.05
O-GlcNAc signalling: implications for cancer cell biology. Nat Rev Cancer (2011) 1.87
Mass spectrometry in the analysis of N-linked and O-linked glycans. Curr Opin Struct Biol (2009) 1.77
Alternative mRNA splicing produces a novel biologically active short isoform of PGC-1alpha. J Biol Chem (2009) 1.67
Peroxisome proliferator-activated receptor gamma coactivator 1alpha or 1beta overexpression inhibits muscle protein degradation, induction of ubiquitin ligases, and disuse atrophy. J Biol Chem (2010) 1.66
Targeting Forkhead box O1 from the concept to metabolic diseases: lessons from mouse models. Antioxid Redox Signal (2010) 1.59
Modulation of transcription factor function by O-GlcNAc modification. Biochim Biophys Acta (2010) 1.55
O-GlcNAc transferase/host cell factor C1 complex regulates gluconeogenesis by modulating PGC-1α stability. Cell Metab (2012) 1.46
O-GlcNAc signaling in the cardiovascular system. Circ Res (2010) 1.43
Nutrient-dependent regulation of PGC-1alpha's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5. Biochim Biophys Acta (2009) 1.39
The FoxO family in cardiac function and dysfunction. Annu Rev Physiol (2010) 1.33
Regulation of insulin receptor substrate 1 (IRS-1)/AKT kinase-mediated insulin signaling by O-Linked beta-N-acetylglucosamine in 3T3-L1 adipocytes. J Biol Chem (2009) 1.28
O-GlcNAcylation increases ChREBP protein content and transcriptional activity in the liver. Diabetes (2011) 1.28
Augmented O-GlcNAc signaling attenuates oxidative stress and calcium overload in cardiomyocytes. Amino Acids (2010) 1.26
GCN5-mediated transcriptional control of the metabolic coactivator PGC-1beta through lysine acetylation. J Biol Chem (2009) 1.23
O-GlcNAc cycling: implications for neurodegenerative disorders. Int J Biochem Cell Biol (2009) 1.22
O-GlcNAc transferase enables AgRP neurons to suppress browning of white fat. Cell (2014) 1.18
Inducible nitric oxide synthase induction underlies lipid-induced hepatic insulin resistance in mice: potential role of tyrosine nitration of insulin signaling proteins. Diabetes (2010) 1.14
O-GlcNAc signaling entrains the circadian clock by inhibiting BMAL1/CLOCK ubiquitination. Cell Metab (2013) 1.14
Protein O-GlcNAcylation in diabetes and diabetic complications. Expert Rev Proteomics (2013) 1.12
Forkhead box class O transcription factors in liver function and disease. J Gastroenterol Hepatol (2013) 1.07
Mitochondria and PGC-1α in Aging and Age-Associated Diseases. J Aging Res (2011) 1.04
Redox regulation of FoxO transcription factors. Redox Biol (2015) 1.01
Separation and identification of isomeric glycopeptides by high field asymmetric waveform ion mobility spectrometry. Anal Chem (2012) 0.99
Multiple tissue-specific roles for the O-GlcNAc post-translational modification in the induction of and complications arising from type II diabetes. J Biol Chem (2014) 0.98
Dynamic O-GlcNAcylation and its roles in the cellular stress response and homeostasis. Cell Stress Chaperones (2013) 0.98
Diabetes-associated dysregulation of O-GlcNAcylation in rat cardiac mitochondria. Proc Natl Acad Sci U S A (2015) 0.97
Autophagy: an affair of the heart. Heart Fail Rev (2013) 0.97
The active site of O-GlcNAc transferase imposes constraints on substrate sequence. Nat Struct Mol Biol (2015) 0.97
O-linked-N-acetylglucosamine cycling and insulin signaling are required for the glucose stress response in Caenorhabditis elegans. Genetics (2011) 0.95
Mechanism, Structure, and Inhibition of O-GlcNAc Processing Enzymes. Curr Signal Transduct Ther (2010) 0.94
Functional crosstalk of PGC-1 coactivators and inflammation in skeletal muscle pathophysiology. Semin Immunopathol (2013) 0.93
Fenofibrate improves renal lipotoxicity through activation of AMPK-PGC-1α in db/db mice. PLoS One (2014) 0.92
O-GlcNAcylation at promoters, nutrient sensors, and transcriptional regulation. Biochim Biophys Acta (2013) 0.91
Glycosylation of the nuclear pore. Traffic (2014) 0.90
Elevated O-GlcNAcylation promotes colonic inflammation and tumorigenesis by modulating NF-κB signaling. Oncotarget (2015) 0.89
The role of O-GlcNAc signaling in the pathogenesis of diabetic retinopathy. Proteomics Clin Appl (2014) 0.88
Electron transfer dissociation (ETD): the mass spectrometric breakthrough essential for O-GlcNAc protein site assignments-a study of the O-GlcNAcylated protein host cell factor C1. Proteomics (2013) 0.88
Cardiomyocyte Ogt is essential for postnatal viability. Am J Physiol Heart Circ Physiol (2013) 0.88
Hepatic FoxO1 integrates glucose utilization and lipid synthesis through regulation of Chrebp O-glycosylation. PLoS One (2012) 0.86
O-GlcNAc transferase and O-GlcNAcase: achieving target substrate specificity. Amino Acids (2014) 0.83
Role of transcription factor modifications in the pathogenesis of insulin resistance. Exp Diabetes Res (2011) 0.82
Pleiotropic and age-dependent effects of decreased protein modification by O-linked N-acetylglucosamine on pancreatic β-cell function and vascularization. J Biol Chem (2011) 0.81
Glucosamine-induced OGT activation mediates glucose production through cleaved Notch1 and FoxO1, which coordinately contributed to the regulation of maintenance of self-renewal in mouse embryonic stem cells. Stem Cells Dev (2014) 0.81
Glucosamine for osteoarthritis: biological effects, clinical efficacy, and safety on glucose metabolism. Arthritis (2014) 0.80
IHG-1 promotes mitochondrial biogenesis by stabilizing PGC-1α. J Am Soc Nephrol (2011) 0.80
O-GlcNAc: A Bittersweet Switch in Liver. Front Endocrinol (Lausanne) (2014) 0.79
Regulation of Oct1/Pou2f1 transcription activity by O-GlcNAcylation. FASEB J (2013) 0.78
O-GlcNAcylation, contractile protein modifications and calcium affinity in skeletal muscle. Front Physiol (2014) 0.78
O-Linked β-N-acetylglucosamine (O-GlcNAc) Acts as a Glucose Sensor to Epigenetically Regulate the Insulin Gene in Pancreatic Beta Cells. J Biol Chem (2015) 0.78
Chronic HMGCR/HMG-CoA reductase inhibitor treatment contributes to dysglycemia by upregulating hepatic gluconeogenesis through autophagy induction. Autophagy (2015) 0.77
Aging leads to elevation of O-GlcNAcylation and disruption of mitochondrial homeostasis in retina. Oxid Med Cell Longev (2014) 0.76
The augmentation of O-GlcNAcylation reduces glyoxal-induced cell injury by attenuating oxidative stress in human retinal microvascular endothelial cells. Int J Mol Med (2015) 0.76
Drosophila O-GlcNAcase Deletion Globally Perturbs Chromatin O-GlcNAcylation. J Biol Chem (2016) 0.76
The Role of the O-GlcNAc Modification in Regulating Eukaryotic Gene Expression. Curr Signal Transduct Ther (2010) 0.76
Memory and synaptic plasticity are impaired by dysregulated hippocampal O-GlcNAcylation. Sci Rep (2017) 0.75
Molecular Functions of Glycoconjugates in Autophagy. J Mol Biol (2016) 0.75
O-GlcNAcylation mediates the control of cytosolic phosphoenolpyruvate carboxykinase activity via Pgc1α. PLoS One (2017) 0.75
The protein kinase complement of the human genome. Science (2002) 35.36
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell (1999) 32.32
Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature (2005) 18.41
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1. Nature (2001) 11.72
Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators. Cell (2006) 10.18
Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction. Nature (2003) 9.77
Cycling of O-linked beta-N-acetylglucosamine on nucleocytoplasmic proteins. Nature (2007) 8.48
PGC-1 coactivators: inducible regulators of energy metabolism in health and disease. J Clin Invest (2006) 6.85
Negative regulation of the forkhead transcription factor FKHR by Akt. J Biol Chem (1999) 5.66
The general transcription machinery and general cofactors. Crit Rev Biochem Mol Biol (2006) 5.52
Cytokine stimulation of energy expenditure through p38 MAP kinase activation of PPARgamma coactivator-1. Mol Cell (2001) 4.58
The O-GlcNAc transferase gene resides on the X chromosome and is essential for embryonic stem cell viability and mouse ontogeny. Proc Natl Acad Sci U S A (2000) 4.55
Activation of PPARgamma coactivator-1 through transcription factor docking. Science (1999) 4.33
An autoregulatory loop controls peroxisome proliferator-activated receptor gamma coactivator 1alpha expression in muscle. Proc Natl Acad Sci U S A (2003) 4.31
Dynamic glycosylation of nuclear and cytosolic proteins. Cloning and characterization of a unique O-GlcNAc transferase with multiple tetratricopeptide repeats. J Biol Chem (1997) 4.24
The hexosamine signaling pathway: deciphering the "O-GlcNAc code". Sci STKE (2005) 4.20
Discovery of a metabolic pathway mediating glucose-induced desensitization of the glucose transport system. Role of hexosamine biosynthesis in the induction of insulin resistance. J Biol Chem (1991) 4.16
Hepatic glucose sensing via the CREB coactivator CRTC2. Science (2008) 4.05
Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance. Nature (2008) 3.98
Metabolic adaptations through the PGC-1 alpha and SIRT1 pathways. FEBS Lett (2007) 3.65
Subfemtomole MS and MS/MS peptide sequence analysis using nano-HPLC micro-ESI fourier transform ion cyclotron resonance mass spectrometry. Anal Chem (2000) 3.38
Dynamic O-GlcNAc modification of nucleocytoplasmic proteins in response to stress. A survival response of mammalian cells. J Biol Chem (2004) 3.35
A neutral loss activation method for improved phosphopeptide sequence analysis by quadrupole ion trap mass spectrometry. Anal Chem (2004) 3.08
Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytes. Proc Natl Acad Sci U S A (2002) 3.08
Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1. Mol Cell (2000) 3.00
Recruitment of O-GlcNAc transferase to promoters by corepressor mSin3A: coupling protein O-GlcNAcylation to transcriptional repression. Cell (2002) 2.89
The utility of ETD mass spectrometry in proteomic analysis. Biochim Biophys Acta (2006) 2.85
RNA polymerase II is a glycoprotein. Modification of the COOH-terminal domain by O-GlcNAc. J Biol Chem (1993) 2.68
Sugar-lectin interactions: how does wheat-germ agglutinin bind sialoglycoconjugates? Eur J Biochem (1980) 2.64
O-GlcNAc a sensor of cellular state: the role of nucleocytoplasmic glycosylation in modulating cellular function in response to nutrition and stress. Biochim Biophys Acta (2004) 2.62
Characterization of a mouse monoclonal antibody specific for O-linked N-acetylglucosamine. Anal Biochem (2001) 2.58
Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1alpha: modulation by p38 MAPK. Genes Dev (2004) 2.39
Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia. Proc Natl Acad Sci U S A (2002) 2.32
PGC-1, a versatile coactivator. Trends Endocrinol Metab (2001) 2.31
Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha. Mol Cell (2003) 2.31
O-GlcNAc regulates FoxO activation in response to glucose. J Biol Chem (2008) 2.27
Discovery of O-GlcNAc transferase inhibitors. J Am Chem Soc (2005) 2.27
Transducer of regulated CREB-binding proteins (TORCs) induce PGC-1alpha transcription and mitochondrial biogenesis in muscle cells. Proc Natl Acad Sci U S A (2006) 2.26
Reciprocity between O-GlcNAc and O-phosphate on the carboxyl terminal domain of RNA polymerase II. Biochemistry (2001) 2.24
Hexosamines, insulin resistance, and the complications of diabetes: current status. Am J Physiol Endocrinol Metab (2006) 2.12
Convergence of peroxisome proliferator-activated receptor gamma and Foxo1 signaling pathways. J Biol Chem (2003) 1.99
A Caenorhabditis elegans model of insulin resistance: altered macronutrient storage and dauer formation in an OGT-1 knockout. Proc Natl Acad Sci U S A (2005) 1.93
Activation of nuclear receptor coactivator PGC-1alpha by arginine methylation. Genes Dev (2005) 1.92
Methods for analyzing peptides and proteins on a chromatographic timescale by electron-transfer dissociation mass spectrometry. Nat Protoc (2008) 1.87
AMP-activated protein kinase and p38 MAPK activate O-GlcNAcylation of neuronal proteins during glucose deprivation. J Biol Chem (2008) 1.86
SCFCdc4 acts antagonistically to the PGC-1alpha transcriptional coactivator by targeting it for ubiquitin-mediated proteolysis. Genes Dev (2008) 1.78
Increased hexosamine biosynthesis and protein O-GlcNAc levels associated with myocardial protection against calcium paradox and ischemia. J Mol Cell Cardiol (2005) 1.66
Glucose deprivation stimulates O-GlcNAc modification of proteins through up-regulation of O-linked N-acetylglucosaminyltransferase. J Biol Chem (2008) 1.64
O-linked beta-N-acetylglucosaminyltransferase substrate specificity is regulated by myosin phosphatase targeting and other interacting proteins. J Biol Chem (2008) 1.64
Activation of cardiac Cdk9 represses PGC-1 and confers a predisposition to heart failure. EMBO J (2004) 1.62
Increased enzymatic O-GlcNAcylation of mitochondrial proteins impairs mitochondrial function in cardiac myocytes exposed to high glucose. J Biol Chem (2008) 1.62
Identification and cloning of a novel family of coiled-coil domain proteins that interact with O-GlcNAc transferase. J Biol Chem (2002) 1.60
Regulation of the O-linked beta-N-acetylglucosamine transferase by insulin signaling. J Biol Chem (2008) 1.45
Glucosamine cardioprotection in perfused rat hearts associated with increased O-linked N-acetylglucosamine protein modification and altered p38 activation. Am J Physiol Heart Circ Physiol (2007) 1.37
Non-canonical glycosyltransferase modulates post-hypoxic cardiac myocyte death and mitochondrial permeability transition. J Mol Cell Cardiol (2008) 1.36
Signal transduction. Sweet conundrum. Science (2008) 0.83
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet (2003) 53.59
Resveratrol improves health and survival of mice on a high-calorie diet. Nature (2006) 20.91
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha. Cell (2006) 19.16
Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature (2005) 18.41
Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres. Nature (2002) 14.37
Peptide and protein sequence analysis by electron transfer dissociation mass spectrometry. Proc Natl Acad Sci U S A (2004) 13.14
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity. Nature (2009) 10.59
Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae. Nat Biotechnol (2002) 8.37
Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha. EMBO J (2007) 7.30
mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex. Nature (2007) 7.12
Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle. Proc Natl Acad Sci U S A (2004) 6.53
Histone methyltransferases direct different degrees of methylation to define distinct chromatin domains. Mol Cell (2003) 6.44
Regulation of HP1-chromatin binding by histone H3 methylation and phosphorylation. Nature (2005) 6.40
A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis. Nature (2002) 6.19
Set2 is a nucleosomal histone H3-selective methyltransferase that mediates transcriptional repression. Mol Cell Biol (2002) 5.42
Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment. Nature (2009) 5.32
Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry. Proc Natl Acad Sci U S A (2007) 5.09
Fasting-dependent glucose and lipid metabolic response through hepatic sirtuin 1. Proc Natl Acad Sci U S A (2007) 4.87
SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis. EMBO J (2007) 4.66
GCN5 acetyltransferase complex controls glucose metabolism through transcriptional repression of PGC-1alpha. Cell Metab (2006) 4.50
Lenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cells. Science (2013) 4.39
Regulation of hepatic fasting response by PPARgamma coactivator-1alpha (PGC-1): requirement for hepatocyte nuclear factor 4alpha in gluconeogenesis. Proc Natl Acad Sci U S A (2003) 4.34
Novel linear quadrupole ion trap/FT mass spectrometer: performance characterization and use in the comparative analysis of histone H3 post-translational modifications. J Proteome Res (2004) 4.32
Aurora B phosphorylates centromeric MCAK and regulates its localization and microtubule depolymerization activity. Curr Biol (2004) 4.20
Peroxisome proliferator-activated receptor gamma coactivator 1beta (PGC-1beta ), a novel PGC-1-related transcription coactivator associated with host cell factor. J Biol Chem (2001) 4.20
Organismal differences in post-translational modifications in histones H3 and H4. J Biol Chem (2006) 3.84
Chemical derivatization of histones for facilitated analysis by mass spectrometry. Nat Protoc (2007) 3.78
Gene silencing: trans-histone regulatory pathway in chromatin. Nature (2002) 3.77
Protein identification using sequential ion/ion reactions and tandem mass spectrometry. Proc Natl Acad Sci U S A (2005) 3.77
Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes. Proc Natl Acad Sci U S A (2003) 3.75
PGC1α expression defines a subset of human melanoma tumors with increased mitochondrial capacity and resistance to oxidative stress. Cancer Cell (2013) 3.71
Metabolic adaptations through the PGC-1 alpha and SIRT1 pathways. FEBS Lett (2007) 3.65
Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction. J Biol Chem (2006) 3.40
Dynamic O-GlcNAc modification of nucleocytoplasmic proteins in response to stress. A survival response of mammalian cells. J Biol Chem (2004) 3.35
Cathepsin L proteolytically processes histone H3 during mouse embryonic stem cell differentiation. Cell (2008) 3.09
Cell signaling, the essential role of O-GlcNAc! Biochim Biophys Acta (2006) 3.09
A neutral loss activation method for improved phosphopeptide sequence analysis by quadrupole ion trap mass spectrometry. Anal Chem (2004) 3.08
Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytes. Proc Natl Acad Sci U S A (2002) 3.08
Expression patterns and post-translational modifications associated with mammalian histone H3 variants. J Biol Chem (2005) 3.00
p38 mitogen-activated protein kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene. Mol Cell Biol (2004) 3.00
Mapping sites of O-GlcNAc modification using affinity tags for serine and threonine post-translational modifications. Mol Cell Proteomics (2002) 2.88
The utility of ETD mass spectrometry in proteomic analysis. Biochim Biophys Acta (2006) 2.85
Discrimination among individual Watson-Crick base pairs at the termini of single DNA hairpin molecules. Nucleic Acids Res (2003) 2.81
Extensive crosstalk between O-GlcNAcylation and phosphorylation regulates cytokinesis. Sci Signal (2010) 2.79
Perturbations in O-linked beta-N-acetylglucosamine protein modification cause severe defects in mitotic progression and cytokinesis. J Biol Chem (2005) 2.74
O-GlcNAcylation regulates phosphorylation of tau: a mechanism involved in Alzheimer's disease. Proc Natl Acad Sci U S A (2004) 2.67
O-linked beta-N-acetylglucosamine (O-GlcNAc): Extensive crosstalk with phosphorylation to regulate signaling and transcription in response to nutrients and stress. Biochim Biophys Acta (2009) 2.64
O-GlcNAc a sensor of cellular state: the role of nucleocytoplasmic glycosylation in modulating cellular function in response to nutrition and stress. Biochim Biophys Acta (2004) 2.62
Ogt-dependent X-chromosome-linked protein glycosylation is a requisite modification in somatic cell function and embryo viability. Mol Cell Biol (2004) 2.56
Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP. Genes Dev (2010) 2.55
MAPKAP kinase 2 phosphorylates tristetraprolin on in vivo sites including Ser178, a site required for 14-3-3 binding. J Biol Chem (2003) 2.53
Beta-N-acetylglucosamine (O-GlcNAc) is part of the histone code. Proc Natl Acad Sci U S A (2010) 2.47
Cross-talk between GlcNAcylation and phosphorylation: site-specific phosphorylation dynamics in response to globally elevated O-GlcNAc. Proc Natl Acad Sci U S A (2008) 2.45
Long-distance combinatorial linkage between methylation and acetylation on histone H3 N termini. Proc Natl Acad Sci U S A (2007) 2.43
Cross-talk between GlcNAcylation and phosphorylation: roles in insulin resistance and glucose toxicity. Am J Physiol Endocrinol Metab (2008) 2.40
EMRE is an essential component of the mitochondrial calcium uniporter complex. Science (2013) 2.39
Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1alpha: modulation by p38 MAPK. Genes Dev (2004) 2.39
The cAMP/PKA pathway rapidly activates SIRT1 to promote fatty acid oxidation independently of changes in NAD(+). Mol Cell (2011) 2.36
N-terminal alpha-methylation of RCC1 is necessary for stable chromatin association and normal mitosis. Nat Cell Biol (2007) 2.36
Insulin controls subcellular localization and multisite phosphorylation of the phosphatidic acid phosphatase, lipin 1. J Biol Chem (2006) 2.32
The vertebrate Ndc80 complex contains Spc24 and Spc25 homologs, which are required to establish and maintain kinetochore-microtubule attachment. Curr Biol (2004) 2.31
Mass spectrometry analysis of Arabidopsis histone H3 reveals distinct combinations of post-translational modifications. Nucleic Acids Res (2004) 2.28
O-GlcNAc regulates FoxO activation in response to glucose. J Biol Chem (2008) 2.27