Published in Mol Cell Biol on September 01, 2005
The histone variant mH2A1.1 interferes with transcription by down-regulating PARP-1 enzymatic activity. Genes Dev (2006) 1.95
Dynamic nucleosomes. Chromosome Res (2006) 1.93
The histone variant macroH2A1 marks repressed autosomal chromatin, but protects a subset of its target genes from silencing. Genes Dev (2009) 1.82
The histone variant macroH2A is an epigenetic regulator of key developmental genes. Nat Struct Mol Biol (2009) 1.75
Mechanism of polymerase II transcription repression by the histone variant macroH2A. Mol Cell Biol (2006) 1.75
Differential regulation and predictive potential of MacroH2A1 isoforms in colon cancer. Am J Pathol (2012) 1.71
Histone variant macroH2A confers resistance to nuclear reprogramming. EMBO J (2011) 1.57
Epigenetic determination of a cell-specific gene expression program by ATF-2 and the histone variant macroH2A. EMBO J (2006) 1.54
MacroH2A1 and ATM Play Opposing Roles in Paracrine Senescence and the Senescence-Associated Secretory Phenotype. Mol Cell (2015) 1.53
The roles of PARP1 in gene control and cell differentiation. Curr Opin Genet Dev (2010) 1.40
QKI-mediated alternative splicing of the histone variant MacroH2A1 regulates cancer cell proliferation. Mol Cell Biol (2011) 1.38
Histone H2A variants in nucleosomes and chromatin: more or less stable? Nucleic Acids Res (2012) 1.33
The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket. J Virol (2009) 1.32
Nucleosome structural studies. Curr Opin Struct Biol (2010) 1.32
Epigenetic aberrations and cancer. Mol Cancer (2006) 1.29
macroH2A1 histone variants are depleted on active genes but concentrated on the inactive X chromosome. Mol Cell Biol (2006) 1.28
Histone variants: dynamic punctuation in transcription. Genes Dev (2014) 1.22
Histone variants: emerging players in cancer biology. Cell Mol Life Sci (2013) 1.17
PARP-14 functions as a transcriptional switch for Stat6-dependent gene activation. J Biol Chem (2010) 1.14
Epigenetic factors influencing resistance to nuclear reprogramming. Trends Genet (2011) 1.14
MacroH2A1 regulates the balance between self-renewal and differentiation commitment in embryonic and adult stem cells. Mol Cell Biol (2012) 1.11
Histone variant macroH2A marks embryonic differentiation in vivo and acts as an epigenetic barrier to induced pluripotency. J Cell Sci (2012) 1.10
ATRX-mediated chromatin association of histone variant macroH2A1 regulates α-globin expression. Genes Dev (2012) 1.10
MacroH2A allows ATP-dependent chromatin remodeling by SWI/SNF and ACF complexes but specifically reduces recruitment of SWI/SNF. Biochemistry (2008) 1.08
Structure of the Drosophila nucleosome core particle highlights evolutionary constraints on the H2A-H2B histone dimer. Proteins (2008) 1.07
The nsP3 macro domain is important for Sindbis virus replication in neurons and neurovirulence in mice. Virology (2009) 1.06
Nucleosome structure and function. Chem Rev (2014) 1.02
The end adjusts the means: heterochromatin remodelling during terminal cell differentiation. Chromosome Res (2006) 0.99
Skp2-macroH2A1-CDK8 axis orchestrates G2/M transition and tumorigenesis. Nat Commun (2015) 0.98
Geometry of the nucleosomal DNA superhelix. Biophys J (2008) 0.97
The SARS-unique domain (SUD) of SARS coronavirus contains two macrodomains that bind G-quadruplexes. PLoS Pathog (2009) 0.96
Rapid elimination of the histone variant MacroH2A from somatic cell heterochromatin after nuclear transfer. Cell Reprogram (2010) 0.95
Crystal structures of the X-domains of a Group-1 and a Group-3 coronavirus reveal that ADP-ribose-binding may not be a conserved property. Protein Sci (2009) 0.93
The linker region of macroH2A promotes self-association of nucleosomal arrays. J Biol Chem (2011) 0.91
The histone domain of macroH2A1 contains several dispersed elements that are each sufficient to direct enrichment on the inactive X chromosome. J Mol Biol (2007) 0.89
Nuclear magnetic resonance structure shows that the severe acute respiratory syndrome coronavirus-unique domain contains a macrodomain fold. J Virol (2008) 0.88
Nucleosome adaptability conferred by sequence and structural variations in histone H2A-H2B dimers. Curr Opin Struct Biol (2015) 0.87
DNA architecture, deformability, and nucleosome positioning. J Biomol Struct Dyn (2010) 0.87
Macro histone variants are critical for the differentiation of human pluripotent cells. J Biol Chem (2013) 0.85
The histone variant MacroH2A1 regulates target gene expression in part by recruiting the transcriptional coregulator PELP1. Mol Cell Biol (2014) 0.85
The basic linker of macroH2A stabilizes DNA at the entry/exit site of the nucleosome. Nucleic Acids Res (2012) 0.84
The histone variant MacroH2A regulates Ca(2+) influx through TRPC3 and TRPC6 channels. Oncogenesis (2013) 0.83
Revealing transient structures of nucleosomes as DNA unwinds. Nucleic Acids Res (2014) 0.83
Chromatin Dynamics in Vivo: A Game of Musical Chairs. Genes (Basel) (2015) 0.82
Genome-wide analysis of the chromatin composition of histone H2A and H3 variants in mouse embryonic stem cells. PLoS One (2014) 0.81
MacroH2A subtypes contribute antagonistically to the transcriptional regulation of the ribosomal cistron during seasonal acclimatization of the carp fish. Epigenetics Chromatin (2010) 0.80
The right place at the right time: chaperoning core histone variants. EMBO Rep (2015) 0.80
Histone variants as emerging regulators of embryonic stem cell identity. Epigenetics (2015) 0.79
An ensemble of B-DNA dinucleotide geometries lead to characteristic nucleosomal DNA structure and provide plasticity required for gene expression. BMC Struct Biol (2011) 0.79
Effects of MacroH2A and H2A.Z on Nucleosome Dynamics as Elucidated by Molecular Dynamics Simulations. Biophys J (2016) 0.78
The histone H2A variant macroH2A1 does not localize to the centrosome. PLoS One (2011) 0.77
In Vitro Chromatin Assembly: Strategies and Quality Control. Methods Enzymol (2016) 0.77
Macro Domain from Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Is an Efficient ADP-ribose Binding Module: CRYSTAL STRUCTURE AND BIOCHEMICAL STUDIES. J Biol Chem (2016) 0.76
The Structural Determinants behind the Epigenetic Role of Histone Variants. Genes (Basel) (2015) 0.76
The Histone Variant MacroH2A1.2 Is Necessary for the Activation of Muscle Enhancers and Recruitment of the Transcription Factor Pbx1. Cell Rep (2016) 0.75
The macro domain as fusion tag for carrier-driven crystallization. Protein Sci (2016) 0.75
Chromatin changes in reprogramming of mammalian somatic cells. Rejuvenation Res (2014) 0.75
Loss of histone variant macroH2A2 expression associates with progression of anal neoplasm. J Clin Pathol (2015) 0.75
The characterization of macroH2A beyond vertebrates supports an ancestral origin and conserved role for histone variants in chromatin. Epigenetics (2016) 0.75
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Crystal structure of the nucleosome core particle at 2.8 A resolution. Nature (1997) 44.55
Histone H3.1 and H3.3 complexes mediate nucleosome assembly pathways dependent or independent of DNA synthesis. Cell (2004) 10.16
ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex. Science (2003) 10.04
The histone variant H3.3 marks active chromatin by replication-independent nucleosome assembly. Mol Cell (2002) 9.80
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FACT facilitates transcription-dependent nucleosome alteration. Science (2003) 5.83
A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1. Mol Cell (2003) 5.57
A protein complex containing the conserved Swi2/Snf2-related ATPase Swr1p deposits histone variant H2A.Z into euchromatin. PLoS Biol (2004) 5.02
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The macro domain is an ADP-ribose binding module. EMBO J (2005) 4.07
Crystal structure of a nucleosome core particle containing the variant histone H2A.Z. Nat Struct Biol (2000) 4.05
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MacroH2A, a core histone containing a large nonhistone region. Science (1992) 2.96
The essential histone variant H2A.Z regulates the equilibrium between different chromatin conformational states. Nat Struct Biol (2002) 2.63
Evolutionary conservation of histone macroH2A subtypes and domains. Nucleic Acids Res (1998) 2.63
The histone variant macroH2A interferes with transcription factor binding and SWI/SNF nucleosome remodeling. Mol Cell (2003) 2.29
Characterization of the stability and folding of H2A.Z chromatin particles: implications for transcriptional activation. J Biol Chem (2001) 1.77
Crystal structures of nucleosome core particles in complex with minor groove DNA-binding ligands. J Mol Biol (2003) 1.63
Higher concentrations of histone macroH2A in the Barr body are correlated with higher nucleosome density. Curr Biol (2000) 1.56
The crystal structure of AF1521 a protein from Archaeoglobus fulgidus with homology to the non-histone domain of macroH2A. J Mol Biol (2003) 1.44
Dynamic relocation of epigenetic chromatin markers reveals an active role of constitutive heterochromatin in the transition from proliferation to quiescence. J Cell Sci (2004) 1.30
Cdyl: a new transcriptional co-repressor. EMBO Rep (2003) 1.18
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Solvent mediated interactions in the structure of the nucleosome core particle at 1.9 a resolution. J Mol Biol (2002) 8.42
Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification. Cell (2011) 5.27
Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA. Dev Cell (2005) 4.83
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In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation. EMBO J (2002) 4.28
Structural determinants for generating centromeric chromatin. Nature (2004) 4.25
HDAC-6 interacts with and deacetylates tubulin and microtubules in vivo. EMBO J (2003) 3.96
Differential histone modifications mark mouse imprinting control regions during spermatogenesis. EMBO J (2007) 3.46
The nucleosomal surface as a docking station for Kaposi's sarcoma herpesvirus LANA. Science (2006) 3.46
Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally. Mol Cell Biol (2008) 2.85
Cooperative binding of two acetylation marks on a histone tail by a single bromodomain. Nature (2009) 2.83
The histone chaperone Nap1 promotes nucleosome assembly by eliminating nonnucleosomal histone DNA interactions. Mol Cell (2010) 2.69
H2A.Z alters the nucleosome surface to promote HP1alpha-mediated chromatin fiber folding. Mol Cell (2004) 2.63
The essential histone variant H2A.Z regulates the equilibrium between different chromatin conformational states. Nat Struct Biol (2002) 2.63
HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates. Genes Dev (2007) 2.56
HDAC6-p97/VCP controlled polyubiquitin chain turnover. EMBO J (2006) 2.52
A new fluorescence resonance energy transfer approach demonstrates that the histone variant H2AZ stabilizes the histone octamer within the nucleosome. J Biol Chem (2004) 2.33
The histone variant macroH2A interferes with transcription factor binding and SWI/SNF nucleosome remodeling. Mol Cell (2003) 2.29
Acetylation-dependent chromatin reorganization by BRDT, a testis-specific bromodomain-containing protein. Mol Cell Biol (2003) 2.22
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The role of histones in chromatin remodelling during mammalian spermiogenesis. Eur J Biochem (2004) 2.10
Histone chaperones in nucleosome eviction and histone exchange. Curr Opin Struct Biol (2008) 2.09
Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions. EMBO J (2004) 2.08
Nucleosome assembly protein 1 exchanges histone H2A-H2B dimers and assists nucleosome sliding. J Biol Chem (2004) 2.08
Assembly and mechanosensory function of focal adhesions: experiments and models. Eur J Cell Biol (2005) 2.06
Phosphorylation of histone H4 Ser1 regulates sporulation in yeast and is conserved in fly and mouse spermatogenesis. Genes Dev (2006) 2.05
Pericentric heterochromatin reprogramming by new histone variants during mouse spermiogenesis. J Cell Biol (2007) 1.96
HSP27 is a ubiquitin-binding protein involved in I-kappaBalpha proteasomal degradation. Mol Cell Biol (2003) 1.96
A charged and contoured surface on the nucleosome regulates chromatin compaction. Nat Struct Mol Biol (2007) 1.95
Histone chaperones and nucleosome assembly. Curr Opin Struct Biol (2003) 1.94
Histone deacetylase 9 couples neuronal activity to muscle chromatin acetylation and gene expression. Nat Neurosci (2005) 1.92
The core histone N-terminal tail domains function independently and additively during salt-dependent oligomerization of nucleosomal arrays. J Biol Chem (2005) 1.91
A novel Rho-mDia2-HDAC6 pathway controls podosome patterning through microtubule acetylation in osteoclasts. J Cell Sci (2005) 1.87
Stress-induced transcription of satellite III repeats. J Cell Biol (2003) 1.86
A unified phylogeny-based nomenclature for histone variants. Epigenetics Chromatin (2012) 1.82
Nucleosome-binding affinity as a primary determinant of the nuclear mobility of the pioneer transcription factor FoxA. Genes Dev (2009) 1.82
Tip60 is targeted to proteasome-mediated degradation by Mdm2 and accumulates after UV irradiation. EMBO J (2002) 1.81
Ectopic activation of germline and placental genes identifies aggressive metastasis-prone lung cancers. Sci Transl Med (2013) 1.79
Developmental changes in histone macroH2A1-mediated gene regulation. Mol Cell Biol (2007) 1.77
Regulation of protein turnover by acetyltransferases and deacetylases. Biochimie (2007) 1.75
The effect of H3K79 dimethylation and H4K20 trimethylation on nucleosome and chromatin structure. Nat Struct Mol Biol (2008) 1.73
Nucleosomes containing the histone variant H2A.Bbd organize only 118 base pairs of DNA. EMBO J (2004) 1.67
Class II histone deacetylases are directly recruited by BCL6 transcriptional repressor. J Biol Chem (2002) 1.67
Differentiation of NUT midline carcinoma by epigenomic reprogramming. Cancer Res (2011) 1.65
From meiosis to postmeiotic events: the secrets of histone disappearance. FEBS J (2009) 1.65
Bromodomain-dependent stage-specific male genome programming by Brdt. EMBO J (2012) 1.64
Structure and function of nucleosome assembly proteins. Biochem Cell Biol (2006) 1.64
Histone chaperone FACT coordinates nucleosome interaction through multiple synergistic binding events. J Biol Chem (2011) 1.63
Crystal structures of nucleosome core particles in complex with minor groove DNA-binding ligands. J Mol Biol (2003) 1.63
Functional interaction between class II histone deacetylases and ICP0 of herpes simplex virus type 1. J Virol (2004) 1.59
Oncogenesis by sequestration of CBP/p300 in transcriptionally inactive hyperacetylated chromatin domains. EMBO J (2010) 1.58
Preferential binding of the histone (H3-H4)2 tetramer by NAP1 is mediated by the amino-terminal histone tails. J Biol Chem (2003) 1.56
Regulation of microtubule dynamics by inhibition of the tubulin deacetylase HDAC6. J Cell Sci (2009) 1.55
Nucleosome accessibility governed by the dimer/tetramer interface. Nucleic Acids Res (2010) 1.55
HDAC6 controls the kinetics of platelet activation. Blood (2012) 1.54
Nucleosome core particles containing a poly(dA.dT) sequence element exhibit a locally distorted DNA structure. J Mol Biol (2006) 1.52
Regulatory cross-talk between lysine acetylation and ubiquitination: role in the control of protein stability. Bioessays (2005) 1.51
Role of the tetradecapeptide repeat domain of human histone deacetylase 6 in cytoplasmic retention. J Biol Chem (2004) 1.47
Structure and Scm3-mediated assembly of budding yeast centromeric nucleosomes. Nat Commun (2011) 1.46
The tale of protein lysine acetylation in the cytoplasm. J Biomed Biotechnol (2010) 1.44
Nucleosome structure(s) and stability: variations on a theme. Annu Rev Biophys (2011) 1.43
Histone chaperone specificity in Rtt109 activation. Nat Struct Mol Biol (2008) 1.42
Establishment of male-specific epigenetic information. Gene (2005) 1.42
HDAC6 a new cellular stress surveillance factor. Cell Cycle (2007) 1.40
MacroH2A histone variants act as a barrier upon reprogramming towards pluripotency. Nat Commun (2013) 1.39
A thermodynamic model for Nap1-histone interactions. J Biol Chem (2008) 1.36
The histone chaperone FACT: structural insights and mechanisms for nucleosome reorganization. J Biol Chem (2011) 1.34
Replacement of histone H3 with CENP-A directs global nucleosome array condensation and loosening of nucleosome superhelical termini. Proc Natl Acad Sci U S A (2011) 1.33
Histone chaperone FACT action during transcription through chromatin by RNA polymerase II. Proc Natl Acad Sci U S A (2013) 1.32
Two catalytic domains are required for protein deacetylation. J Biol Chem (2005) 1.31
Loss of histone H4K20 trimethylation occurs in preneoplasia and influences prognosis of non-small cell lung cancer. Clin Cancer Res (2008) 1.31
Structural and biophysical studies of human PARP-1 in complex with damaged DNA. J Mol Biol (2009) 1.31
Dynamic relocation of epigenetic chromatin markers reveals an active role of constitutive heterochromatin in the transition from proliferation to quiescence. J Cell Sci (2004) 1.30
macroH2A1 histone variants are depleted on active genes but concentrated on the inactive X chromosome. Mol Cell Biol (2006) 1.28
Molecular recognition of the nucleosomal "supergroove". Proc Natl Acad Sci U S A (2004) 1.25
p14ARF activates a Tip60-dependent and p53-independent ATM/ATR/CHK pathway in response to genotoxic stress. Mol Cell Biol (2006) 1.25
Chromatin-to-nucleoprotamine transition is controlled by the histone H2B variant TH2B. Genes Dev (2013) 1.24
Acetylation and phosphorylation of SRSF2 control cell fate decision in response to cisplatin. EMBO J (2010) 1.23
Meiotic sex chromosome inactivation in male mice with targeted disruptions of Xist. J Cell Sci (2002) 1.22
Histone crotonylation specifically marks the haploid male germ cell gene expression program: post-meiotic male-specific gene expression. Bioessays (2011) 1.22
CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin. EMBO J (2009) 1.21
HSP27 favors ubiquitination and proteasomal degradation of p27Kip1 and helps S-phase re-entry in stressed cells. FASEB J (2006) 1.21
Real-time imaging of histone H4 hyperacetylation in living cells. Proc Natl Acad Sci U S A (2009) 1.20
Yeast CAF-1 assembles histone (H3-H4)2 tetramers prior to DNA deposition. Nucleic Acids Res (2012) 1.18
Cdyl: a new transcriptional co-repressor. EMBO Rep (2003) 1.18
Systematic screen reveals new functional dynamics of histones H3 and H4 during gametogenesis. Genes Dev (2010) 1.17
The DEK oncoprotein is a Su(var) that is essential to heterochromatin integrity. Genes Dev (2011) 1.17
Fluorescence strategies for high-throughput quantification of protein interactions. Nucleic Acids Res (2011) 1.16
Identification of a novel BET bromodomain inhibitor-sensitive, gene regulatory circuit that controls Rituximab response and tumour growth in aggressive lymphoid cancers. EMBO Mol Med (2013) 1.16
Genome-wide distribution of macroH2A1 histone variants in mouse liver chromatin. Mol Cell Biol (2010) 1.15
Site-specific introduction of an acetyl-lysine mimic into peptides and proteins by cysteine alkylation. J Am Chem Soc (2010) 1.15
macroH2A1-dependent silencing of endogenous murine leukemia viruses. Mol Cell Biol (2008) 1.14
HIV-1 Tat targets Tip60 to impair the apoptotic cell response to genotoxic stresses. EMBO J (2005) 1.14
The viral control of cellular acetylation signaling. Bioessays (2003) 1.13
A new insight into male genome reprogramming by histone variants and histone code. Cell Cycle (2008) 1.12
The histone variant macro-H2A preferentially forms "hybrid nucleosomes". J Biol Chem (2006) 1.12
Heat-shock factor 1 controls genome-wide acetylation in heat-shocked cells. Mol Biol Cell (2009) 1.12
p300-mediated tax transactivation from recombinant chromatin: histone tail deletion mimics coactivator function. Mol Cell Biol (2002) 1.12