Published in Mol Cell Biol on December 01, 2005
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The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells. Genes Dev (2007) 6.77
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Polycomb complex 2 is required for E-cadherin repression by the Snail1 transcription factor. Mol Cell Biol (2008) 2.57
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Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation. Genes Dev (2009) 2.36
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DNA methylation in development and human disease. Mutat Res (2008) 1.74
Ubiquitin E3 ligase Ring1b/Rnf2 of polycomb repressive complex 1 contributes to stable maintenance of mouse embryonic stem cells. PLoS One (2008) 1.72
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DNA methyltransferase controls stem cell aging by regulating BMI1 and EZH2 through microRNAs. PLoS One (2011) 1.27
DNMT1 and DNMT3B modulate distinct polycomb-mediated histone modifications in colon cancer. Cancer Res (2009) 1.26
Changes in the distributions and dynamics of polycomb repressive complexes during embryonic stem cell differentiation. Mol Cell Biol (2008) 1.26
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DNA hypermethylation accompanied by transcriptional repression in follicular lymphoma. Genes Chromosomes Cancer (2009) 1.16
A multifactorial signature of DNA sequence and polycomb binding predicts aberrant CpG island methylation. Cancer Res (2009) 1.15
Evidence for alteration of EZH2, BMI1, and KDM6A and epigenetic reprogramming in human papillomavirus type 16 E6/E7-expressing keratinocytes. J Virol (2011) 1.08
Akt phosphorylates the transcriptional repressor bmi1 to block its effects on the tumor-suppressing ink4a-arf locus. Sci Signal (2012) 1.06
Dietary manipulation of histone structure and function. Annu Rev Nutr (2008) 1.02
Decreased expression of Bmi1 is closely associated with cellular senescence in small bile ducts in primary biliary cirrhosis. Am J Pathol (2006) 1.02
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Superior efficacy of a combined epigenetic therapy against human mantle cell lymphoma cells. Clin Cancer Res (2012) 0.99
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EZH2 dependent H3K27me3 is involved in epigenetic silencing of ID4 in prostate cancer. Oncotarget (2014) 0.94
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DNA methylation is a guardian of stem cell self-renewal and multipotency. Nat Genet (2009) 0.81
Tumor-secreted Hsp90 subverts polycomb function to drive prostate tumor growth and invasion. J Biol Chem (2015) 0.81
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Cbx2 stably associates with mitotic chromosomes via a PRC2- or PRC1-independent mechanism and is needed for recruiting PRC1 complex to mitotic chromosomes. Mol Biol Cell (2014) 0.80
YC-1 inhibits proliferation of breast cancer cells by down-regulating EZH2 expression via activation of c-Cbl and ERK. Br J Pharmacol (2014) 0.80
Histone acetylation and DNA demethylation of T cells result in an anaplastic large cell lymphoma-like phenotype. Haematologica (2012) 0.79
Expression Profiling of DNA Methylation and Transcriptional Repression Associated Genes in Lens Epithelium Cells of Age-Related Cataract. Cell Mol Neurobiol (2016) 0.78
Dysregulation of the Bmi-1/p16(Ink⁴a) pathway provokes an aging-associated decline of submandibular gland function. Aging Cell (2015) 0.78
The Polycomb Repressive Complex 1 Protein BMI1 Is Required for Constitutive Heterochromatin Formation and Silencing in Mammalian Somatic Cells. J Biol Chem (2015) 0.77
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Targeting of BMI-1 with PTC-209 shows potent anti-myeloma activity and impairs the tumour microenvironment. J Hematol Oncol (2016) 0.76
BMI1 suffers a degrading experience. Cell Cycle (2011) 0.75
Ephemeral Protein Binding to DNA Shapes Stable Nuclear Bodies and Chromatin Domains. Biophys J (2017) 0.75
MDR1 mediated chemoresistance: BMI1 and TIP60 in action. Biochim Biophys Acta (2016) 0.75
STAT3 signaling drives EZH2 transcriptional activation and mediates poor prognosis in gastric cancer. Mol Cancer (2016) 0.75
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A Genome-wide multidimensional RNAi screen reveals pathways controlling MHC class II antigen presentation. Cell (2011) 1.14
Polycomb function during oogenesis is required for mouse embryonic development. Genes Dev (2012) 1.09
Neuronal ceroid lipofuscinosis protein CLN3 interacts with motor proteins and modifies location of late endosomal compartments. Cell Mol Life Sci (2012) 1.09
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Thymocyte proliferation induced by pre-T cell receptor signaling is maintained through polycomb gene product Bmi-1-mediated Cdkn2a repression. Immunity (2008) 1.05
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Bmi1 is required for Hedgehog pathway-driven medulloblastoma expansion. Neoplasia (2008) 1.04
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The serine-threonine kinase LKB1 is essential for survival under energetic stress in zebrafish. Proc Natl Acad Sci U S A (2011) 1.00
Small regulators, major consequences - Ca²⁺ and cholesterol at the endosome-ER interface. J Cell Sci (2014) 1.00
B cell receptor-mediated internalization of salmonella: a novel pathway for autonomous B cell activation and antibody production. J Immunol (2009) 1.00
PKA-induced phosphorylation of ERα at serine 305 and high PAK1 levels is associated with sensitivity to tamoxifen in ER-positive breast cancer. Breast Cancer Res Treat (2010) 0.99
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Cholesterol-binding molecules MLN64 and ORP1L mark distinct late endosomes with transporters ABCA3 and NPC1. J Lipid Res (2013) 0.97
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