Association of physical activity and body mass index with novel and traditional cardiovascular biomarkers in women.

PubWeight™: 2.99‹?› | Rank: Top 1%

🔗 View Article (PMID 16551713)

Published in JAMA on March 22, 2006

Authors

Samia Mora1, I-Min Lee, Julie E Buring, Paul M Ridker

Author Affiliations

1: Donald W. Reynolds Center for Cardiovascular Research, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass 02215, USA. smora2@partners.org

Articles citing this

Physical activity and weight gain prevention. JAMA (2010) 5.27

Physical activity and reduced risk of cardiovascular events: potential mediating mechanisms. Circulation (2007) 3.20

Physical inactivity rapidly induces insulin resistance and microvascular dysfunction in healthy volunteers. Arterioscler Thromb Vasc Biol (2007) 2.07

Physical activity and risk of stroke in women. Stroke (2010) 1.85

Novel associations of CPS1, MUT, NOX4, and DPEP1 with plasma homocysteine in a healthy population: a genome-wide evaluation of 13 974 participants in the Women's Genome Health Study. Circ Cardiovasc Genet (2009) 1.71

Role of self-care in management of diabetes mellitus. J Diabetes Metab Disord (2013) 1.70

Caloric restriction alone and with exercise improves CVD risk in healthy non-obese individuals. Atherosclerosis (2008) 1.58

Lifestyle interaction with fat mass and obesity-associated (FTO) genotype and risk of obesity in apparently healthy U.S. women. Diabetes Care (2011) 1.44

Caloric restriction in humans: impact on physiological, psychological, and behavioral outcomes. Antioxid Redox Signal (2010) 1.42

Cardiac aging: from molecular mechanisms to significance in human health and disease. Antioxid Redox Signal (2012) 1.40

The use of high-sensitivity assays for C-reactive protein in clinical practice. Nat Clin Pract Cardiovasc Med (2008) 1.21

A novel protein glycan biomarker and future cardiovascular disease events. J Am Heart Assoc (2014) 1.13

Effect of caloric restriction in non-obese humans on physiological, psychological and behavioral outcomes. Physiol Behav (2008) 1.13

Physical activity and breast cancer risk among women in the southwestern United States. Ann Epidemiol (2007) 1.12

General and abdominal adiposity and risk of stroke in Chinese women. Stroke (2009) 1.06

Vigorous-intensity leisure-time physical activity and risk of major chronic disease in men. Med Sci Sports Exerc (2012) 1.06

Marriage protects men from clinically meaningful elevations in C-reactive protein: results from the National Social Life, Health, and Aging Project (NSHAP). Psychosom Med (2009) 1.04

The fat-mass and obesity-associated (FTO) gene, physical activity, and risk of incident cardiovascular events in white women. Am Heart J (2010) 1.03

Socioeconomic position, health behaviors, and C-reactive protein: a moderated-mediation analysis. Health Psychol (2010) 1.02

Body mass index, physical activity, and serum markers of inflammation, immunity, and insulin resistance. Cancer Epidemiol Biomarkers Prev (2014) 1.01

Physical activity and high-sensitivity C-reactive protein: the multi-ethnic study of atherosclerosis. Am J Prev Med (2008) 1.00

Relation of body composition to body mass index in HIV-infected patients with metabolic abnormalities. J Acquir Immune Defic Syndr (2008) 0.98

Vigorous physical activity, mediating biomarkers, and risk of myocardial infarction. Med Sci Sports Exerc (2011) 0.98

Changes in physical fitness predict improvements in modifiable cardiovascular risk factors independently of body weight loss in subjects with type 2 diabetes participating in the Italian Diabetes and Exercise Study (IDES). Diabetes Care (2012) 0.97

High-density lipoprotein particle subclass heterogeneity and incident coronary heart disease. Circ Cardiovasc Qual Outcomes (2013) 0.95

The effects of body acupuncture on obesity: anthropometric parameters, lipid profile, and inflammatory and immunologic markers. ScientificWorldJournal (2012) 0.94

High levels of inflammatory biomarkers are associated with increased allele-specific apolipoprotein(a) levels in African-Americans. J Clin Endocrinol Metab (2008) 0.94

Lipoprotein subclass abnormalities and incident hypertension in initially healthy women. Clin Chem (2011) 0.92

Fat or fit: what is more important? Diabetes Care (2009) 0.92

No reduction in C-reactive protein following a 12-month randomized controlled trial of exercise in men and women. Cancer Epidemiol Biomarkers Prev (2008) 0.92

The effect of aerobic versus strength-based training on high-sensitivity C-reactive protein in older adults. Eur J Appl Physiol (2010) 0.92

Impact of genetic and environmental factors on hsCRP concentrations and response to therapeutic agents. Clin Chem (2008) 0.90

Inflammatory cytokines in general and central obesity and modulating effects of physical activity. PLoS One (2015) 0.90

Muscular strength and incident hypertension in normotensive and prehypertensive men. Med Sci Sports Exerc (2010) 0.87

Longitudinal relationship between physical activity and cardiometabolic factors in overweight and obese adults. Eur J Appl Physiol (2009) 0.87

Physical activity and mammographic breast density: a systematic review. Breast Cancer Res Treat (2012) 0.86

Overweight adults may have the lowest mortality--do they have the best health? Am J Epidemiol (2011) 0.85

Meeting physical activity guidelines is associated with reduced risk for cardiovascular disease in black South African women; a 5.5-year follow-up study. BMC Public Health (2014) 0.85

Association between mobility mode and C-reactive protein levels in men with chronic spinal cord injury. Arch Phys Med Rehabil (2008) 0.84

The influence of cardiac rehabilitation on inflammation and metabolic syndrome in women with coronary heart disease. J Cardiovasc Nurs (2010) 0.84

Ambulatory activity associations with cardiovascular and metabolic risk factors in smokers. J Phys Act Health (2011) 0.83

Epidemiology of Hypertension Stages in Two Countries in Sub-Sahara Africa: Factors Associated with Hypertension Stages. Int J Hypertens (2015) 0.83

Circulating N-Linked Glycoprotein Acetyls and Longitudinal Mortality Risk. Circ Res (2016) 0.83

Physical Activity, Bone Health, and Obesity in Peri-/Pre- and Postmenopausal Women: Results from the EPIC-Potsdam Study. Calcif Tissue Int (2015) 0.82

The effects of exercise on cardiovascular biomarkers in patients with chronic heart failure. Am Heart J (2013) 0.82

Consumption of less than 10% of total energy from added sugars is associated with increasing HDL in females during adolescence: a longitudinal analysis. J Am Heart Assoc (2014) 0.82

Association between the interleukin-6 promoter polymorphism -174G/C and serum lipoprotein(a) concentrations in humans. PLoS One (2011) 0.82

The influence of systematic pulse-limited physical exercise on the parameters of the cardiovascular system in patients over 65 years of age. Arch Med Sci (2013) 0.82

Exercise: friend or foe? Nat Rev Cardiol (2013) 0.81

The association between physical activity and the risk of incident psoriasis. Arch Dermatol (2012) 0.81

Smoking cessation program with exercise improves cardiovascular disease biomarkers in sedentary women. J Womens Health (Larchmt) (2011) 0.81

Decline in physical activity level in the Childhood Cancer Survivor Study cohort. Cancer Epidemiol Biomarkers Prev (2014) 0.81

The "fit but fat" paradigm addressed using accelerometer-determined physical activity data. N Am J Med Sci (2014) 0.80

Combination of physical activity, nutrition, or other metabolic factors and vaccine response. Front Biosci (2007) 0.80

Association of recreational physical activity with homocysteine, folate and lipid markers in young women. Eur J Appl Physiol (2008) 0.80

Paradoxical association of lipoprotein measures with incident atrial fibrillation. Circ Arrhythm Electrophysiol (2014) 0.80

Impact of lifestyle factors on trends in lipid profiles among Korean adolescents: the Korea National Health and Nutrition Examination Surveys study, 1998 and 2010. Korean J Pediatr (2016) 0.79

Lipid biomarkers and long-term risk of cancer in the Women's Health Study. Am J Clin Nutr (2016) 0.79

Tomato-based food products are related to clinically modest improvements in selected coronary biomarkers in women. J Nutr (2012) 0.79

A situation-specific theory of Midlife Women's Attitudes Toward Physical Activity (MAPA). Nurs Outlook (2010) 0.79

Physical activity, genes for physical fitness, and risk of coronary heart disease. Med Sci Sports Exerc (2013) 0.77

Multiancestral analysis of inflammation-related genetic variants and C-reactive protein in the population architecture using genomics and epidemiology study. Circ Cardiovasc Genet (2014) 0.77

Effect of diet or diet plus physical activity versus usual care on inflammatory markers in patients with newly diagnosed type 2 diabetes: the Early ACTivity in Diabetes (ACTID) randomized, controlled trial. J Am Heart Assoc (2014) 0.76

Nonexercise physical activity and inflammatory and oxidative stress markers in women. J Womens Health (Larchmt) (2013) 0.76

Is the association of continuous metabolic syndrome risk score with body mass index independent of physical activity? The CASPIAN-III study. Nutr Res Pract (2015) 0.76

Effects of lifestyle measures, antiobesity agents, and bariatric surgery on serological markers of inflammation in obese patients. Mediators Inflamm (2010) 0.76

The Effects of Muscle Mass on Homocyst(e)ine Levels in Plasma and Urine. Int J Exerc Sci (2012) 0.75

Premature Atherosclerotic Cardiovascular Disease in Childhood Cancer Survivors. Prog Pediatr Cardiol (2015) 0.75

Physical Activity, Sedentary Behavior, and Inflammatory and Hemostatic Markers in Men. Med Sci Sports Exerc (2017) 0.75

Effect of prolonged standardized bed rest on cystatin C and other markers of cardiovascular risk. BMC Physiol (2011) 0.75

Physical activity, body mass index, and cardiovascular biomarkers in women. JAMA (2006) 0.75

General and Central Obesity in Two Iranian Ethnic Groups Living in Urmia, West Azerbaijan, Iran: Effect of the Neighborhood Environment. Iran Red Crescent Med J (2016) 0.75

Physical Activity among Veterans and Nonveterans with Diabetes. J Aging Res (2012) 0.75

Psychosocial Variables Related to Why Women are Less Active than Men and Related Health Implications. Clin Med Insights Womens Health (2016) 0.75

Effect of Acupuncture on Body Weight Reduction and Inflammatory Mediators in Egyptian Obese Patients. Open Access Maced J Med Sci (2015) 0.75

Articles by these authors

Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08

Inflammation and atherosclerosis. Circulation (2002) 20.77

Physical activity and public health: updated recommendation for adults from the American College of Sports Medicine and the American Heart Association. Med Sci Sports Exerc (2007) 20.11

Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01

Physical activity and public health: updated recommendation for adults from the American College of Sports Medicine and the American Heart Association. Circulation (2007) 18.32

A randomized trial of low-dose aspirin in the primary prevention of cardiovascular disease in women. N Engl J Med (2005) 17.32

Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events. N Engl J Med (2002) 16.23

Development and validation of improved algorithms for the assessment of global cardiovascular risk in women: the Reynolds Risk Score. JAMA (2007) 15.32

American College of Sports Medicine position stand. Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: guidance for prescribing exercise. Med Sci Sports Exerc (2011) 14.42

Body-mass index and mortality among 1.46 million white adults. N Engl J Med (2010) 13.34

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25

Vitamin E in the primary prevention of cardiovascular disease and cancer: the Women's Health Study: a randomized controlled trial. JAMA (2005) 12.09

Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women. JAMA (2007) 9.68

Progress and challenges in translating the biology of atherosclerosis. Nature (2011) 9.41

Low-dose aspirin in the primary prevention of cancer: the Women's Health Study: a randomized controlled trial. JAMA (2005) 9.03

From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I. Circulation (2003) 8.61

A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1). Nat Genet (2009) 8.39

Vitamins E and C in the prevention of cardiovascular disease in men: the Physicians' Health Study II randomized controlled trial. JAMA (2008) 8.32

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94

Advances in measuring the effect of individual predictors of cardiovascular risk: the role of reclassification measures. Ann Intern Med (2009) 7.62

Long term effects of dietary sodium reduction on cardiovascular disease outcomes: observational follow-up of the trials of hypertension prevention (TOHP). BMJ (2007) 7.54

Blood levels of long-chain n-3 fatty acids and the risk of sudden death. N Engl J Med (2002) 7.32

C-reactive protein, the metabolic syndrome, and risk of incident cardiovascular events: an 8-year follow-up of 14 719 initially healthy American women. Circulation (2003) 6.99

Population analysis of large copy number variants and hotspots of human genetic disease. Am J Hum Genet (2009) 6.79

C-reactive protein, fibrinogen, and cardiovascular disease prediction. N Engl J Med (2012) 6.39

Migraine and risk of cardiovascular disease in women. JAMA (2006) 6.16

Sex hormone-binding globulin and risk of type 2 diabetes in women and men. N Engl J Med (2009) 6.16

Inflammation in atherosclerosis: from pathophysiology to practice. J Am Coll Cardiol (2009) 6.11

Effect of sleep loss on C-reactive protein, an inflammatory marker of cardiovascular risk. J Am Coll Cardiol (2004) 6.08

Cardiovascular disease risk prediction with and without knowledge of genetic variation at chromosome 9p21.3. Ann Intern Med (2009) 6.00

Sugar-sweetened beverages and genetic risk of obesity. N Engl J Med (2012) 5.98

Hemoglobin A1c predicts diabetes but not cardiovascular disease in nondiabetic women. Am J Med (2007) 5.95

Effect of folic acid and B vitamins on risk of cardiovascular events and total mortality among women at high risk for cardiovascular disease: a randomized trial. JAMA (2008) 5.92

C-reactive protein and the risk of developing hypertension. JAMA (2003) 5.75

Non-HDL cholesterol, apolipoproteins A-I and B100, standard lipid measures, lipid ratios, and CRP as risk factors for cardiovascular disease in women. JAMA (2005) 5.74

The effect of including C-reactive protein in cardiovascular risk prediction models for women. Ann Intern Med (2006) 5.69

New loci associated with kidney function and chronic kidney disease. Nat Genet (2010) 5.58

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet (2012) 5.48

Measures of obesity and cardiovascular risk among men and women. J Am Coll Cardiol (2008) 5.28

Physical activity and weight gain prevention. JAMA (2010) 5.27

Multivitamins in the prevention of cancer in men: the Physicians' Health Study II randomized controlled trial. JAMA (2012) 5.25

Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer. Nat Genet (2009) 5.14

Vitamins E and C in the prevention of prostate and total cancer in men: the Physicians' Health Study II randomized controlled trial. JAMA (2008) 5.13

Migraine and cardiovascular disease: systematic review and meta-analysis. BMJ (2009) 4.98

Inactivating mutations in NPC1L1 and protection from coronary heart disease. N Engl J Med (2014) 4.94

A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33. Nat Genet (2010) 4.89

Multiple loci associated with indices of renal function and chronic kidney disease. Nat Genet (2009) 4.78

Risk of death and cardiovascular events in initially healthy women with new-onset atrial fibrillation. JAMA (2011) 4.73

Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis. PLoS Genet (2009) 4.71

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies. Lancet (2012) 4.63

Association of LDL cholesterol, non-HDL cholesterol, and apolipoprotein B levels with risk of cardiovascular events among patients treated with statins: a meta-analysis. JAMA (2012) 4.49

Pharmacogenetic study of statin therapy and cholesterol reduction. JAMA (2004) 4.47

Association between a literature-based genetic risk score and cardiovascular events in women. JAMA (2010) 4.46

A randomized trial of rosuvastatin in the prevention of venous thromboembolism. N Engl J Med (2009) 4.46

Prevalence of dry eye syndrome among US women. Am J Ophthalmol (2003) 4.46

Rationale, design, and methodology of the Women's Genome Health Study: a genome-wide association study of more than 25,000 initially healthy american women. Clin Chem (2007) 4.45

Multivitamins in the prevention of cardiovascular disease in men: the Physicians' Health Study II randomized controlled trial. JAMA (2012) 4.40

Statins for the primary prevention of cardiovascular events in women with elevated high-sensitivity C-reactive protein or dyslipidemia: results from the Justification for the Use of Statins in Prevention: An Intervention Trial Evaluating Rosuvastatin (JUPITER) and meta-analysis of women from primary prevention trials. Circulation (2010) 4.37

Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study. Am J Hum Genet (2008) 4.31

Inflammation as a cardiovascular risk factor. Circulation (2004) 4.26

From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part II. Circulation (2003) 3.94

Lipoprotein particle profiles by nuclear magnetic resonance compared with standard lipids and apolipoproteins in predicting incident cardiovascular disease in women. Circulation (2009) 3.93

Anti-inflammatory effects of statins: clinical evidence and basic mechanisms. Nat Rev Drug Discov (2005) 3.92

Lipid-related markers and cardiovascular disease prediction. JAMA (2012) 3.91

Dose response between physical activity and risk of coronary heart disease: a meta-analysis. Circulation (2011) 3.84

Genome-wide association studies identify four ER negative-specific breast cancer risk loci. Nat Genet (2013) 3.81

Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Nat Genet (2012) 3.71

Detectable clonal mosaicism and its relationship to aging and cancer. Nat Genet (2012) 3.69

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation (2011) 3.68

2013 AHA/ACC guideline on lifestyle management to reduce cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation (2013) 3.63

Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein. Am J Hum Genet (2008) 3.61

Methods for pooling results of epidemiologic studies: the Pooling Project of Prospective Studies of Diet and Cancer. Am J Epidemiol (2006) 3.41

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet (2011) 3.40

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet (2010) 3.37

A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer. Nat Genet (2011) 3.37

A randomized factorial trial of vitamins C and E and beta carotene in the secondary prevention of cardiovascular events in women: results from the Women's Antioxidant Cardiovascular Study. Arch Intern Med (2007) 3.37

2013 AHA/ACC guideline on lifestyle management to reduce cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol (2013) 3.35

Relationship of physical activity vs body mass index with type 2 diabetes in women. JAMA (2004) 3.31

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet (2013) 3.25

Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes. Hum Mol Genet (2010) 3.24

Blood pressure and risk of developing type 2 diabetes mellitus: the Women's Health Study. Eur Heart J (2007) 3.21

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21

Physical activity and reduced risk of cardiovascular events: potential mediating mechanisms. Circulation (2007) 3.20