Published in Pharmacogenet Genomics on June 01, 2006
A synonymous polymorphism in a common MDR1 (ABCB1) haplotype shapes protein function. Biochim Biophys Acta (2009) 1.79
Selected ABCB1, ABCB4 and ABCC2 polymorphisms do not enhance the risk of drug-induced hepatotoxicity in a Spanish cohort. PLoS One (2014) 1.39
Very important pharmacogene summary: ABCB1 (MDR1, P-glycoprotein). Pharmacogenet Genomics (2011) 1.29
Bayesian survival analysis in genetic association studies. Bioinformatics (2008) 0.86
Multidrug resistance-associated protein-1 (MRP1) genetic variants, MRP1 protein levels and severity of COPD. Respir Res (2010) 0.85
Association of ABCB1 polymorphisms with prognostic outcomes of anthracycline and cytarabine in Chinese patients with acute myeloid leukemia. Eur J Clin Pharmacol (2015) 0.85
Multidrug resistance-associated protein 1 (MRP1/ABCC1) polymorphism: from discovery to clinical application. Zhong Nan Da Xue Xue Bao Yi Xue Ban (2011) 0.82
Gene-wide characterization of common quantitative trait loci for ABCB1 mRNA expression in normal liver tissues in the Chinese population. PLoS One (2012) 0.81
Comparative description of haplotype structure and genetic diversity of MDR1 (ABCB1) in HIV-positive and HIV-negative populations. Infect Genet Evol (2009) 0.81
Genetic variation of the ABC transporter gene ABCC1 (Multidrug resistance protein 1 - MRP1) in the Polish population. BMC Genet (2015) 0.78
miR-134: A Human Cancer Suppressor? Mol Ther Nucleic Acids (2016) 0.77
Association of MDR1 gene C3435T polymorphism with childhood intractable epilepsy: a meta-analysis. J Neural Transm (Vienna) (2014) 0.77
A linkage and association analysis study in the multidrug resistance gene 1 (mdr1) in renal patients. Int J Mol Epidemiol Genet (2012) 0.75
Initial sequencing and comparative analysis of the mouse genome. Nature (2002) 96.15
Accurate whole human genome sequencing using reversible terminator chemistry. Nature (2008) 90.20
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007) 75.09
A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature (2007) 35.08
Dynamic repertoire of a eukaryotic transcriptome surveyed at single-nucleotide resolution. Nature (2008) 18.84
DNA methylation profiling of human chromosomes 6, 20 and 22. Nat Genet (2006) 18.08
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
The genome sequence of Caenorhabditis briggsae: a platform for comparative genomics. PLoS Biol (2003) 13.32
Approximate Bayesian computation in population genetics. Genetics (2002) 13.06
Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature (2003) 13.00
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature (2010) 12.27
Prepublication data sharing. Nature (2009) 12.24
Complete MHC haplotype sequencing for common disease gene mapping. Genome Res (2004) 12.09
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet (2012) 11.09
Target-enrichment strategies for next-generation sequencing. Nat Methods (2010) 8.78
The zebrafish reference genome sequence and its relationship to the human genome. Nature (2013) 8.52
Epigenome-wide association studies for common human diseases. Nat Rev Genet (2011) 7.96
A novel CpG island set identifies tissue-specific methylation at developmental gene loci. PLoS Biol (2008) 7.95
De novo mutations in epileptic encephalopathies. Nature (2013) 7.42
The DNA sequence of the human X chromosome. Nature (2005) 6.97
Architectures of somatic genomic rearrangement in human cancer amplicons at sequence-level resolution. Genome Res (2007) 6.91
Faciobrachial dystonic seizures precede Lgi1 antibody limbic encephalitis. Ann Neurol (2011) 6.77
Simultaneous analysis of all SNPs in genome-wide and re-sequencing association studies. PLoS Genet (2008) 6.66
The genome of the blood fluke Schistosoma mansoni. Nature (2009) 5.94
Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity. Nat Genet (2007) 5.68
Analyses of pig genomes provide insight into porcine demography and evolution. Nature (2012) 5.58
Common genetic variation near MC4R is associated with waist circumference and insulin resistance. Nat Genet (2008) 5.55
Identifying adaptive genetic divergence among populations from genome scans. Mol Ecol (2004) 5.31
A physical map of the mouse genome. Nature (2002) 4.97
Assessment of cumulative evidence on genetic associations: interim guidelines. Int J Epidemiol (2007) 4.96
The Medicago genome provides insight into the evolution of rhizobial symbioses. Nature (2011) 4.94
hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. Genomics (2007) 4.62
Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C9 and VKORC1 genotypes and warfarin dosing. Clin Pharmacol Ther (2011) 4.42
Bayesian statistical methods for genetic association studies. Nat Rev Genet (2009) 4.37
Prominent use of distal 5' transcription start sites and discovery of a large number of additional exons in ENCODE regions. Genome Res (2007) 4.33
Genome-wide and fine-resolution association analysis of malaria in West Africa. Nat Genet (2009) 4.30
Variation analysis and gene annotation of eight MHC haplotypes: the MHC Haplotype Project. Immunogenetics (2008) 4.25
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet (2014) 4.13
Insights into hominid evolution from the gorilla genome sequence. Nature (2012) 4.12
Sequence-level population simulations over large genomic regions. Genetics (2007) 4.04
Inferring population history with DIY ABC: a user-friendly approach to approximate Bayesian computation. Bioinformatics (2008) 4.02
Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. Hum Mol Genet (2008) 3.93
HLA-A*3101 and carbamazepine-induced hypersensitivity reactions in Europeans. N Engl J Med (2011) 3.93
Which drugs cause preventable admissions to hospital? A systematic review. Br J Clin Pharmacol (2006) 3.56
Improved heritability estimation from genome-wide SNPs. Am J Hum Genet (2012) 3.48
Genome-wide significance for dense SNP and resequencing data. Genet Epidemiol (2008) 3.26
Large-scale mutagenesis in p19(ARF)- and p53-deficient mice identifies cancer genes and their collaborative networks. Cell (2008) 3.25
Faciobrachial dystonic seizures: the influence of immunotherapy on seizure control and prevention of cognitive impairment in a broadening phenotype. Brain (2013) 3.22
Nodulation signaling in legumes requires NSP2, a member of the GRAS family of transcriptional regulators. Science (2005) 3.19
A conserved supergene locus controls colour pattern diversity in Heliconius butterflies. PLoS Biol (2006) 3.15
AIP mutation in pituitary adenomas in the 18th century and today. N Engl J Med (2011) 3.14
TranscriptSNPView: a genome-wide catalog of mouse coding variation. Nat Genet (2006) 3.10
Research capacity. Enabling the genomic revolution in Africa. Science (2014) 3.05
Spread of an inactive form of caspase-12 in humans is due to recent positive selection. Am J Hum Genet (2006) 3.00
Logistic regression protects against population structure in genetic association studies. Genome Res (2005) 2.94
Genetic analysis of completely sequenced disease-associated MHC haplotypes identifies shuffling of segments in recent human history. PLoS Genet (2006) 2.80
Transcriptional regulation of the stem cell leukemia gene (SCL)--comparative analysis of five vertebrate SCL loci. Genome Res (2002) 2.77
Pharmacodynamic and pharmacokinetic study of oral Curcuma extract in patients with colorectal cancer. Clin Cancer Res (2001) 2.69
Chromosomal rearrangements maintain a polymorphic supergene controlling butterfly mimicry. Nature (2011) 2.65
Legume genome evolution viewed through the Medicago truncatula and Lotus japonicus genomes. Proc Natl Acad Sci U S A (2006) 2.61
Rare deletions at 16p13.11 predispose to a diverse spectrum of sporadic epilepsy syndromes. Am J Hum Genet (2010) 2.61
Impact of CYP2B6 983T>C polymorphism on non-nucleoside reverse transcriptase inhibitor plasma concentrations in HIV-infected patients. J Antimicrob Chemother (2008) 2.52
Pharmacogenetics of warfarin: current status and future challenges. Pharmacogenomics J (2006) 2.40
HLA genotype and carbamazepine-induced cutaneous adverse drug reactions: a systematic review. Clin Pharmacol Ther (2012) 2.36
A functional genomics approach reveals novel quantitative trait loci associated with platelet signaling pathways. Blood (2009) 2.25
A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order. J Allergy Clin Immunol (2011) 2.24
Fregene: simulation of realistic sequence-level data in populations and ascertained samples. BMC Bioinformatics (2008) 2.23
Integration of genetic, clinical, and INR data to refine warfarin dosing. Clin Pharmacol Ther (2010) 2.21
Conservation of the H19 noncoding RNA and H19-IGF2 imprinting mechanism in therians. Nat Genet (2008) 2.20
Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels. Nat Genet (2009) 2.19
Population structure and inbreeding from pedigree analysis of purebred dogs. Genetics (2008) 2.14
The relative contribution of NSAIDs and Helicobacter pylori to the aetiology of endoscopically-diagnosed peptic ulcer disease: observations from a tertiary referral hospital in the UK between 2005 and 2010. Aliment Pharmacol Ther (2012) 2.10
Evolutionary breakpoints in the gibbon suggest association between cytosine methylation and karyotype evolution. PLoS Genet (2009) 2.07
The evolution of the DLK1-DIO3 imprinted domain in mammals. PLoS Biol (2008) 2.05
A genome-wide, end-sequenced 129Sv BAC library resource for targeting vector construction. Genomics (2005) 2.02
Nilotinib concentration in cell lines and primary CD34(+) chronic myeloid leukemia cells is not mediated by active uptake or efflux by major drug transporters. Leukemia (2009) 1.99
Genome-wide association mapping to candidate polymorphism resolution in the unsequenced barley genome. Proc Natl Acad Sci U S A (2010) 1.96
Coping with cold: An integrative, multitissue analysis of the transcriptome of a poikilothermic vertebrate. Proc Natl Acad Sci U S A (2004) 1.93
Genetic association of the major histocompatibility complex with rheumatoid arthritis implicates two non-DRB1 loci. Arthritis Rheum (2009) 1.92
Mutagenic insertion and chromosome engineering resource (MICER). Nat Genet (2004) 1.88
A high utility integrated map of the pig genome. Genome Biol (2007) 1.88
Clinical pharmacogenetics implementation consortium guidelines for HLA-B genotype and abacavir dosing. Clin Pharmacol Ther (2012) 1.88
DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. Nature (2006) 1.81
Predictors of kidney tubular dysfunction in HIV-infected patients treated with tenofovir: a pharmacogenetic study. Clin Infect Dis (2009) 1.81
Analysis of multiple genomic sequence alignments: a web resource, online tools, and lessons learned from analysis of mammalian SCL loci. Genome Res (2004) 1.80
Exon array CGH: detection of copy-number changes at the resolution of individual exons in the human genome. Am J Hum Genet (2005) 1.78
Crop genome sequencing: lessons and rationales. Trends Plant Sci (2011) 1.77
Attitudes and knowledge of hospital pharmacists to adverse drug reaction reporting. Br J Clin Pharmacol (2001) 1.77
Plasma HIV-1 RNA detection below 50 copies/ml and risk of virologic rebound in patients receiving highly active antiretroviral therapy. Clin Infect Dis (2012) 1.76
Swine Genome Sequencing Consortium (SGSC): a strategic roadmap for sequencing the pig genome. Comp Funct Genomics (2005) 1.75
Current assessment of risk-benefit by regulators: is it time to introduce decision analyses? Clin Pharmacol Ther (2007) 1.70
Neural correlates of speech anticipatory anxiety in generalized social phobia. Neuroreport (2004) 1.69
High-resolution transcriptional analysis of the regulatory influence of cell-to-cell signalling reveals novel genes that contribute to Xanthomonas phytopathogenesis. Mol Microbiol (2013) 1.68
Common genetic variation and susceptibility to partial epilepsies: a genome-wide association study. Brain (2010) 1.67
Heritability of left ventricular mass in a large cohort of twins. J Hypertens (2006) 1.65
Common genetic variation near melatonin receptor MTNR1B contributes to raised plasma glucose and increased risk of type 2 diabetes among Indian Asians and European Caucasians. Diabetes (2009) 1.65