Investigating the role of small, acid-soluble spore proteins (SASPs) in the resistance of Clostridium perfringens spores to heat.

PubWeight™: 1.19‹?› | Rank: Top 10%

🔗 View Article (PMC 1501028)

Published in BMC Microbiol on June 08, 2006

Authors

Deepa Raju1, Michael Waters, Peter Setlow, Mahfuzur R Sarker

Author Affiliations

1: Department of Biomedical Sciences, College of Veterinary Medicine, Oregon State University, Corvallis, Oregon 97331, USA. rajud@onid.orst.edu

Articles citing this

Characterization of Clostridium perfringens spores that lack SpoVA proteins and dipicolinic acid. J Bacteriol (2008) 1.53

The transcriptional program underlying the physiology of clostridial sporulation. Genome Biol (2008) 1.48

A novel small acid soluble protein variant is important for spore resistance of most Clostridium perfringens food poisoning isolates. PLoS Pathog (2008) 1.27

SleC is essential for cortex peptidoglycan hydrolysis during germination of spores of the pathogenic bacterium Clostridium perfringens. J Bacteriol (2009) 1.22

Antisense-RNA-mediated decreased synthesis of small, acid-soluble spore proteins leads to decreased resistance of clostridium perfringens spores to moist heat and UV radiation. Appl Environ Microbiol (2007) 1.12

Carbon catabolite repression of type IV pilus-dependent gliding motility in the anaerobic pathogen Clostridium perfringens. J Bacteriol (2007) 1.08

Clostridium difficile spore-macrophage interactions: spore survival. PLoS One (2012) 0.97

Roles of DacB and spm proteins in clostridium perfringens spore resistance to moist heat, chemicals, and UV radiation. Appl Environ Microbiol (2008) 0.94

Further characterization of Clostridium perfringens small acid soluble protein-4 (Ssp4) properties and expression. PLoS One (2009) 0.93

Role of GerKB in germination and outgrowth of Clostridium perfringens spores. Appl Environ Microbiol (2009) 0.92

Genotypic and phenotypic characterization of Clostridium perfringens isolates from Darmbrand cases in post-World War II Germany. Infect Immun (2012) 0.91

Microbiological and 16S rRNA analysis of sulphite-reducing clostridia from river sediments in central Italy. BMC Microbiol (2008) 0.88

The Clostridium perfringens germinant receptor protein GerKC is located in the spore inner membrane and is crucial for spore germination. J Bacteriol (2013) 0.85

GerO, a putative Na+/H+-K+ antiporter, is essential for normal germination of spores of the pathogenic bacterium Clostridium perfringens. J Bacteriol (2009) 0.83

Photochemistry and Photobiology of the Spore Photoproduct: A 50-Year Journey. Photochem Photobiol (2015) 0.78

Clostridium perfringens Sporulation and Sporulation-Associated Toxin Production. Microbiol Spectr (2016) 0.78

Effect of a small, acid-soluble spore protein from Clostridium perfringens on the resistance properties of Bacillus subtilis spores. J Bacteriol (2007) 0.76

Variability in DPA and Calcium Content in the Spores of Clostridium Species. Front Microbiol (2016) 0.75

Analysis of Clostridium beijerinckii NCIMB 8052's transcriptional response to ferulic acid and its application to enhance the strain tolerance. Biotechnol Biofuels (2015) 0.75

Multi-functional nano silver: A novel disruptive and theranostic agent for pathogenic organisms in real-time. Sci Rep (2016) 0.75

Rapid and efficient filtration-based procedure for separation and safe analysis of CBRN mixed samples. PLoS One (2014) 0.75

Genetic Characterization of the Exceptionally High Heat Resistance of the Non-toxic Surrogate Clostridium sporogenes PA 3679. Front Microbiol (2017) 0.75

Articles cited by this

beta-Glucuronidase from Escherichia coli as a gene-fusion marker. Proc Natl Acad Sci U S A (1986) 9.05

Resistance of Bacillus endospores to extreme terrestrial and extraterrestrial environments. Microbiol Mol Biol Rev (2000) 6.86

Complete genome sequence of Clostridium perfringens, an anaerobic flesh-eater. Proc Natl Acad Sci U S A (2002) 5.40

Essential role of small, acid-soluble spore proteins in resistance of Bacillus subtilis spores to UV light. J Bacteriol (1986) 4.46

Small, acid-soluble spore proteins of Bacillus species: structure, synthesis, genetics, function, and degradation. Annu Rev Microbiol (1988) 4.26

Mechanisms for the prevention of damage to DNA in spores of Bacillus species. Annu Rev Microbiol (1995) 3.27

Inactivation of the gene (cpe) encoding Clostridium perfringens enterotoxin eliminates the ability of two cpe-positive C. perfringens type A human gastrointestinal disease isolates to affect rabbit ileal loops. Mol Microbiol (1999) 2.99

Comparison of Western immunoblots and gene detection assays for identification of potentially enterotoxigenic isolates of Clostridium perfringens. J Clin Microbiol (1994) 2.81

Virulence studies on chromosomal alpha-toxin and theta-toxin mutants constructed by allelic exchange provide genetic evidence for the essential role of alpha-toxin in Clostridium perfringens-mediated gas gangrene. Mol Microbiol (1995) 2.79

Evidence that the enterotoxin gene can be episomal in Clostridium perfringens isolates associated with non-food-borne human gastrointestinal diseases. J Clin Microbiol (1998) 2.60

Binding of small, acid-soluble spore proteins to DNA plays a significant role in the resistance of Bacillus subtilis spores to hydrogen peroxide. Appl Environ Microbiol (1993) 2.36

Clostridium perfringens-Escherichia coli shuttle vectors that carry single antibiotic resistance determinants. Plasmid (1993) 2.35

Comparative experiments to examine the effects of heating on vegetative cells and spores of Clostridium perfringens isolates carrying plasmid genes versus chromosomal enterotoxin genes. Appl Environ Microbiol (2000) 2.12

Construction of a sequenced Clostridium perfringens-Escherichia coli shuttle plasmid. Plasmid (1992) 2.09

Regulated expression of Clostridium perfringens enterotoxin in naturally cpe-negative type A, B, and C isolates of C. perfringens. Infect Immun (1996) 2.09

Identification and characterization of sporulation-dependent promoters upstream of the enterotoxin gene (cpe) of Clostridium perfringens. J Bacteriol (1998) 2.02

Prevention of DNA damage in spores and in vitro by small, acid-soluble proteins from Bacillus species. J Bacteriol (1993) 1.98

Phenotypic characterization of enterotoxigenic Clostridium perfringens isolates from non-foodborne human gastrointestinal diseases. Anaerobe (1998) 1.88

Interaction between DNA and alpha/beta-type small, acid-soluble spore proteins: a new class of DNA-binding protein. J Bacteriol (1992) 1.70

Expression from the Clostridium perfringens cpe promoter in C. perfringens and Bacillus subtilis. Infect Immun (1994) 1.68

Purification and amino acid sequence of two small, acid-soluble proteins from Clostridium bifermentans spores. FEMS Microbiol Lett (1989) 1.66

Identification of several unique, low-molecular-weight basic proteins in dormant spores of clastridium bifermentans and their degradation during spore germination. J Bacteriol (1976) 1.42

Disruption of the gene (spo0A) encoding sporulation transcription factor blocks endospore formation and enterotoxin production in enterotoxigenic Clostridium perfringens type A. FEMS Microbiol Lett (2004) 1.39

Cloning and nucleotide sequence of three genes coding for small, acid-soluble proteins of Clostridium perfringens spores. FEMS Microbiol Lett (1991) 1.03

Cloning and sequencing of the genes encoding acid-soluble spore proteins from Clostridium perfringens. Gene (1990) 0.82

Articles by these authors

The forespore line of gene expression in Bacillus subtilis. J Mol Biol (2006) 2.52

Germination of spores of Bacillales and Clostridiales species: mechanisms and proteins involved. Trends Microbiol (2010) 2.24

Effects of overexpression of nutrient receptors on germination of spores of Bacillus subtilis. J Bacteriol (2003) 2.21

Association of beta2 toxin production with Clostridium perfringens type A human gastrointestinal disease isolates carrying a plasmid enterotoxin gene. Mol Microbiol (2005) 2.06

Cooperativity between different nutrient receptors in germination of spores of Bacillus subtilis and reduction of this cooperativity by alterations in the GerB receptor. J Bacteriol (2006) 1.87

The products of the spoVA operon are involved in dipicolinic acid uptake into developing spores of Bacillus subtilis. J Bacteriol (2002) 1.72

Studies of the commitment step in the germination of spores of bacillus species. J Bacteriol (2010) 1.68

Isolation and characterization of superdormant spores of Bacillus species. J Bacteriol (2009) 1.65

Role of SpoVA proteins in release of dipicolinic acid during germination of Bacillus subtilis spores triggered by dodecylamine or lysozyme. J Bacteriol (2006) 1.57

Identification of a new gene essential for germination of Bacillus subtilis spores with Ca2+-dipicolinate. J Bacteriol (2003) 1.55

Localization of the cortex lytic enzyme CwlJ in spores of Bacillus subtilis. J Bacteriol (2002) 1.54

Characterization of Clostridium perfringens spores that lack SpoVA proteins and dipicolinic acid. J Bacteriol (2008) 1.53

Lipids in the inner membrane of dormant spores of Bacillus species are largely immobile. Proc Natl Acad Sci U S A (2004) 1.52

Germination proteins in the inner membrane of dormant Bacillus subtilis spores colocalize in a discrete cluster. Mol Microbiol (2011) 1.49

How moist heat kills spores of Bacillus subtilis. J Bacteriol (2007) 1.48

Role of GerD in germination of Bacillus subtilis spores. J Bacteriol (2006) 1.44

A soluble protein is immobile in dormant spores of Bacillus subtilis but is mobile in germinated spores: implications for spore dormancy. Proc Natl Acad Sci U S A (2003) 1.43

Localization of SpoVAD to the inner membrane of spores of Bacillus subtilis. J Bacteriol (2005) 1.42

The Bacillus subtilis spore coat provides "eat resistance" during phagocytic predation by the protozoan Tetrahymena thermophila. Proc Natl Acad Sci U S A (2005) 1.42

Mechanisms of induction of germination of Bacillus subtilis spores by high pressure. Appl Environ Microbiol (2002) 1.42

Disruption of the gene (spo0A) encoding sporulation transcription factor blocks endospore formation and enterotoxin production in enterotoxigenic Clostridium perfringens type A. FEMS Microbiol Lett (2004) 1.39

Effects of a gerF (lgt) mutation on the germination of spores of Bacillus subtilis. J Bacteriol (2004) 1.35

Genotyping and phenotyping of beta2-toxigenic Clostridium perfringens fecal isolates associated with gastrointestinal diseases in piglets. J Clin Microbiol (2003) 1.32

Levels of Ca2+-dipicolinic acid in individual bacillus spores determined using microfluidic Raman tweezers. J Bacteriol (2007) 1.30

The solar UV environment and bacterial spore UV resistance: considerations for Earth-to-Mars transport by natural processes and human spaceflight. Mutat Res (2005) 1.30

Elastic and inelastic light scattering from single bacterial spores in an optical trap allows the monitoring of spore germination dynamics. Anal Chem (2009) 1.29

Factors influencing germination of Bacillus subtilis spores via activation of nutrient receptors by high pressure. Appl Environ Microbiol (2005) 1.28

Factors affecting variability in time between addition of nutrient germinants and rapid dipicolinic acid release during germination of spores of Bacillus species. J Bacteriol (2010) 1.27

Structure of a protein-DNA complex essential for DNA protection in spores of Bacillus species. Proc Natl Acad Sci U S A (2008) 1.27

Analysis of the germination of spores of Bacillus subtilis with temperature sensitive spo mutations in the spoVA operon. FEMS Microbiol Lett (2004) 1.25

Clostridium perfringens spore germination: characterization of germinants and their receptors. J Bacteriol (2007) 1.24

Combination of Raman tweezers and quantitative differential interference contrast microscopy for measurement of dynamics and heterogeneity during the germination of individual bacterial spores. J Biomed Opt (2010) 1.23

SleC is essential for cortex peptidoglycan hydrolysis during germination of spores of the pathogenic bacterium Clostridium perfringens. J Bacteriol (2009) 1.22

Role of dipicolinic acid in resistance and stability of spores of Bacillus subtilis with or without DNA-protective alpha/beta-type small acid-soluble proteins. J Bacteriol (2006) 1.21

Interaction between individual protein components of the GerA and GerB nutrient receptors that trigger germination of Bacillus subtilis spores. J Bacteriol (2005) 1.19

Role of dipicolinic acid in the germination, stability, and viability of spores of Bacillus subtilis. J Bacteriol (2008) 1.19

KCNC3: phenotype, mutations, channel biophysics-a study of 260 familial ataxia patients. Hum Mutat (2010) 1.17

Germination of individual Bacillus subtilis spores with alterations in the GerD and SpoVA proteins, which are important in spore germination. J Bacteriol (2011) 1.15

Effects of sporulation conditions on the germination and germination protein levels of Bacillus subtilis spores. Appl Environ Microbiol (2012) 1.14

Transglutaminase-mediated cross-linking of GerQ in the coats of Bacillus subtilis spores. J Bacteriol (2004) 1.14

Role of a SpoVA protein in dipicolinic acid uptake into developing spores of Bacillus subtilis. J Bacteriol (2012) 1.13

Superdormant spores of Bacillus species have elevated wet-heat resistance and temperature requirements for heat activation. J Bacteriol (2009) 1.13

Antisense-RNA-mediated decreased synthesis of small, acid-soluble spore proteins leads to decreased resistance of clostridium perfringens spores to moist heat and UV radiation. Appl Environ Microbiol (2007) 1.12

Gene expression in Bacillus subtilis surface biofilms with and without sporulation and the importance of yveR for biofilm maintenance. Biotechnol Bioeng (2004) 1.12

Characterization of bacterial spore germination using phase-contrast and fluorescence microscopy, Raman spectroscopy and optical tweezers. Nat Protoc (2011) 1.12

Localization of the germination protein GerD to the inner membrane in Bacillus subtilis spores. J Bacteriol (2008) 1.12

Germination protein levels and rates of germination of spores of Bacillus subtilis with overexpressed or deleted genes encoding germination proteins. J Bacteriol (2012) 1.11

The physical state of water in bacterial spores. Proc Natl Acad Sci U S A (2009) 1.09

Analysis of interactions between nutrient germinant receptors and SpoVA proteins of Bacillus subtilis spores. FEMS Microbiol Lett (2007) 1.08

Carbon catabolite repression of type IV pilus-dependent gliding motility in the anaerobic pathogen Clostridium perfringens. J Bacteriol (2007) 1.08

Levels of germination proteins in dormant and superdormant spores of Bacillus subtilis. J Bacteriol (2012) 1.07

Photosensitization of DNA by dipicolinic acid, a major component of spores of Bacillus species. Photochem Photobiol Sci (2005) 1.07

The protease CspB is essential for initiation of cortex hydrolysis and dipicolinic acid (DPA) release during germination of spores of Clostridium perfringens type A food poisoning isolates. Microbiology (2009) 1.07

Release of small molecules during germination of spores of Bacillus Species. J Bacteriol (2008) 1.06

Characterization of bacterial spore germination using integrated phase contrast microscopy, Raman spectroscopy, and optical tweezers. Anal Chem (2010) 1.04

Characterization of spores of Bacillus subtilis that lack most coat layers. J Bacteriol (2008) 1.04

Structure-based functional studies of the effects of amino acid substitutions in GerBC, the C subunit of the Bacillus subtilis GerB spore germinant receptor. J Bacteriol (2011) 1.02

Identification of new proteins that modulate the germination of spores of bacillus species. J Bacteriol (2013) 1.02

Roles of the major, small, acid-soluble spore proteins and spore-specific and universal DNA repair mechanisms in resistance of Bacillus subtilis spores to ionizing radiation from X rays and high-energy charged-particle bombardment. J Bacteriol (2007) 1.01

Roles of small, acid-soluble spore proteins and core water content in survival of Bacillus subtilis spores exposed to environmental solar UV radiation. Appl Environ Microbiol (2009) 1.01

Monitoring rates and heterogeneity of high-pressure germination of bacillus spores by phase-contrast microscopy of individual spores. Appl Environ Microbiol (2013) 1.01

Chemical effects in biological systems--data dictionary (CEBS-DD): a compendium of terms for the capture and integration of biological study design description, conventional phenotypes, and 'omics data. Toxicol Sci (2005) 1.01

Structure and mechanism of action of a cofactor-dependent phosphoglycerate mutase homolog from Bacillus stearothermophilus with broad specificity phosphatase activity. J Mol Biol (2002) 1.00

Adherence of Clostridium difficile spores to Caco-2 cells in culture. J Med Microbiol (2012) 1.00

Characterization of wet-heat inactivation of single spores of bacillus species by dual-trap Raman spectroscopy and elastic light scattering. Appl Environ Microbiol (2010) 0.99

Structure of the DNA-SspC complex: implications for DNA packaging, protection, and repair in bacterial spores. J Bacteriol (2004) 0.99

Effects of the SpoVT regulatory protein on the germination and germination protein levels of spores of Bacillus subtilis. J Bacteriol (2012) 0.98

Growth, osmotic downshock resistance and differentiation of Bacillus subtilis strains lacking mechanosensitive channels. Arch Microbiol (2007) 0.98

Effects of cortex peptidoglycan structure and cortex hydrolysis on the kinetics of Ca(2+)-dipicolinic acid release during Bacillus subtilis spore germination. J Bacteriol (2011) 0.98

Inorganic phosphate induces spore morphogenesis and enterotoxin production in the intestinal pathogen Clostridium perfringens. Infect Immun (2006) 0.98

Role of the Nfo (YqfS) and ExoA apurinic/apyrimidinic endonucleases in protecting Bacillus subtilis spores from DNA damage. J Bacteriol (2005) 0.98

The Clostridium difficile exosporium cysteine (CdeC)-rich protein is required for exosporium morphogenesis and coat assembly. J Bacteriol (2013) 0.98

Localization of the transglutaminase cross-linking sites in the Bacillus subtilis spore coat protein GerQ. J Bacteriol (2006) 0.97

Topology and accessibility of germination proteins in the Bacillus subtilis spore inner membrane. J Bacteriol (2013) 0.97

Synergism between different germinant receptors in the germination of Bacillus subtilis spores. J Bacteriol (2011) 0.97

YtkD and MutT protect vegetative cells but not spores of Bacillus subtilis from oxidative stress. J Bacteriol (2006) 0.97

Clostridium difficile spore-macrophage interactions: spore survival. PLoS One (2012) 0.97

Numbers of individual nutrient germinant receptors and other germination proteins in spores of Bacillus subtilis. J Bacteriol (2013) 0.96

Kinetics of germination of wet-heat-treated individual spores of Bacillus species, monitored by Raman spectroscopy and differential interference contrast microscopy. Appl Environ Microbiol (2011) 0.96

Differential expression of long noncoding RNAs in the livers of female B6C3F1 mice exposed to the carcinogen furan. Toxicol Sci (2013) 0.96

Effects of Mn and Fe levels on Bacillus subtilis spore resistance and effects of Mn2+, other divalent cations, orthophosphate, and dipicolinic acid on protein resistance to ionizing radiation. Appl Environ Microbiol (2010) 0.96

Differential gene expression to investigate the effect of (5Z)-4-bromo- 5-(bromomethylene)-3-butyl-2(5H)-furanone on Bacillus subtilis. Appl Environ Microbiol (2004) 0.96

Strategy to inactivate Clostridium perfringens spores in meat products. Food Microbiol (2009) 0.95

CodY is a global regulator of virulence-associated properties for Clostridium perfringens type D strain CN3718. MBio (2013) 0.95

Toward a checklist for exchange and interpretation of data from a toxicology study. Toxicol Sci (2007) 0.95

Transcription of the Bacillus subtilis gerK operon, which encodes a spore germinant receptor, and comparison with that of operons encoding other germinant receptors. J Bacteriol (2006) 0.95

Roles of DacB and spm proteins in clostridium perfringens spore resistance to moist heat, chemicals, and UV radiation. Appl Environ Microbiol (2008) 0.94

Analysis of the effects of a gerP mutation on the germination of spores of Bacillus subtilis. J Bacteriol (2012) 0.94

Regulated expression of the beta2-toxin gene (cpb2) in Clostridium perfringens type a isolates from horses with gastrointestinal diseases. J Clin Microbiol (2005) 0.94

Monitoring the kinetics of uptake of a nucleic acid dye during the germination of single spores of Bacillus species. Anal Chem (2010) 0.94

Characterization of single heat-activated Bacillus spores using laser tweezers Raman spectroscopy. Opt Express (2009) 0.93

Further characterization of Clostridium perfringens small acid soluble protein-4 (Ssp4) properties and expression. PLoS One (2009) 0.93