Published in Am J Psychiatry on January 01, 2007
Gene-environment interactions in schizophrenia: review of epidemiological findings and future directions. Schizophr Bull (2008) 2.09
Telomere length and early severe social deprivation: linking early adversity and cellular aging. Mol Psychiatry (2011) 2.01
IQ, educational attainment, memory and plasma lipids: associations with apolipoprotein E genotype in 5995 children. Biol Psychiatry (2011) 1.59
Neurobehavioral evidence for changes in dopamine system activity during adolescence. Neurosci Biobehav Rev (2009) 1.41
Is COMT a susceptibility gene for schizophrenia? Schizophr Bull (2007) 1.14
Musical aptitude is associated with AVPR1A-haplotypes. PLoS One (2009) 1.13
Effects of catechol-O-methyltransferase on normal variation in the cognitive function of children. Am J Psychiatry (2009) 1.05
Dogslife: a web-based longitudinal study of Labrador Retriever health in the UK. BMC Vet Res (2013) 0.99
Lack of association between COMT and working memory in a population-based cohort of healthy young adults. Neuropsychopharmacology (2013) 0.98
Pathways from cannabis to psychosis: a review of the evidence. Front Psychiatry (2013) 0.94
Epistasis between polymorphisms in COMT, ESR1, and GCH1 influences COMT enzyme activity and pain. Pain (2014) 0.91
Convergent lines of evidence support CAMKK2 as a schizophrenia susceptibility gene. Mol Psychiatry (2013) 0.87
Sexually dimorphic effects of catechol-O-methyltransferase (COMT) inhibition on dopamine metabolism in multiple brain regions. PLoS One (2013) 0.86
The effects of gender and catechol O-methyltransferase (COMT) Val108/158Met polymorphism on emotion regulation in velo-cardio-facial syndrome (22q11.2 deletion syndrome): An fMRI study. Neuroimage (2010) 0.85
No association of COMT (Val158Met) genotype with brain structure differences between men and women. PLoS One (2012) 0.82
Attention Deficit Hyperactivity Disorder comorbid oppositional defiant disorder and its predominately inattentive type: evidence for an association with COMT but not MAOA in a Chinese sample. Behav Brain Funct (2009) 0.82
Sex differences in COMT polymorphism effects on prefrontal inhibitory control in adolescence. Neuropsychopharmacology (2014) 0.81
Gonadectomy and hormone replacement exert region- and enzyme isoform-specific effects on monoamine oxidase and catechol-O-methyltransferase activity in prefrontal cortex and neostriatum of adult male rats. Neuroscience (2009) 0.81
Oppositional COMT Val158Met effects on resting state functional connectivity in adolescents and adults. Brain Struct Funct (2014) 0.79
Cognitive effects of genetic variation in monoamine neurotransmitter systems: a population-based study of COMT, MAOA, and 5HTTLPR. Am J Med Genet B Neuropsychiatr Genet (2010) 0.79
Identifying mechanisms that underlie links between COMT genotype and aggression in male adolescents with ADHD. J Child Psychol Psychiatry (2015) 0.79
Preliminary investigation of the influence of dopamine regulating genes on social working memory. Soc Neurosci (2014) 0.78
Catechol-O-methyltransferase Val158Met polymorphism modulates gray matter volume and functional connectivity of the default mode network. PLoS One (2013) 0.78
Hypothesizing Music Intervention Enhances Brain Functional Connectivity Involving Dopaminergic Recruitment: Common Neuro-correlates to Abusable Drugs. Mol Neurobiol (2016) 0.77
Interactive effects of age and multi-gene profile on motor learning and sensorimotor adaptation. Neuropsychologia (2016) 0.77
Genetic polymorphisms of catechol-O-methyltransferase modify the neurobehavioral effects of mercury in children. J Toxicol Environ Health A (2014) 0.77
Genetic influences on insight problem solving: the role of catechol-O-methyltransferase (COMT) gene polymorphisms. Front Psychol (2015) 0.77
The catechol-O-methyltransferase gene (COMT) and cognitive function from childhood through adolescence. Biol Psychol (2012) 0.77
COMT polymorphism modulates the resting-state EEG alpha oscillatory response to acute nicotine in male non-smokers. Genes Brain Behav (2015) 0.75
Inhibition of catechol-O-methyl transferase (COMT) by tolcapone restores reductions in microtubule-associated protein 2 (MAP2) and synaptophysin (SYP) following exposure of neuronal cells to neurotropic HIV. J Neurovirol (2015) 0.75
Catechol-O-methyltransferase val(158)met Polymorphism Interacts with Sex to Affect Face Recognition Ability. Front Psychol (2016) 0.75
COMT and DAT1 genes are associated with hyperactivity and inattention traits in the 1993 Pelotas Birth Cohort: evidence of sex-specific combined effect. J Psychiatry Neurosci (2016) 0.75
The Role of Dopamine in Anticipatory Pursuit Eye Movements: Insights from Genetic Polymorphisms in Healthy Adults. eNeuro (2017) 0.75
Reduced brain activation during inhibitory control in children with COMT Val/Val genotype. Brain Behav (2016) 0.75
A Genetic Variant (COMT) Coding Dopaminergic Activity Predicts Personality Traits in Healthy Elderly. Pers Individ Dif (2015) 0.75
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science (2007) 37.88
Human infection with a novel avian-origin influenza A (H7N9) virus. N Engl J Med (2013) 24.88
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet (2007) 12.62
The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell (2003) 12.50
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature (2010) 12.27
Cohort Profile: the 'children of the 90s'--the index offspring of the Avon Longitudinal Study of Parents and Children. Int J Epidemiol (2012) 11.79
Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review. Lancet (2007) 11.27
Serotonin transporter genetic variation and the response of the human amygdala. Science (2002) 9.31
Maternal seafood consumption in pregnancy and neurodevelopmental outcomes in childhood (ALSPAC study): an observational cohort study. Lancet (2007) 7.85
Factors associated with the development of peanut allergy in childhood. N Engl J Med (2003) 7.82
Cohort Profile: the Avon Longitudinal Study of Parents and Children: ALSPAC mothers cohort. Int J Epidemiol (2012) 6.91
A common variant of HMGA2 is associated with adult and childhood height in the general population. Nat Genet (2007) 6.87
Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder. Am J Hum Genet (2006) 6.27
Genetic basis for individual variations in pain perception and the development of a chronic pain condition. Hum Mol Genet (2004) 5.87
Sex-specific, male-line transgenerational responses in humans. Eur J Hum Genet (2006) 5.72
Maternal antenatal anxiety and children's behavioural/emotional problems at 4 years. Report from the Avon Longitudinal Study of Parents and Children. Br J Psychiatry (2002) 5.16
Trends in access to health services and financial protection in China between 2003 and 2011: a cross-sectional study. Lancet (2012) 4.98
An evaluation of mu-opioid receptor (OPRM1) as a predictor of naltrexone response in the treatment of alcohol dependence: results from the Combined Pharmacotherapies and Behavioral Interventions for Alcohol Dependence (COMBINE) study. Arch Gen Psychiatry (2008) 4.91
Oligodendrocyte dysfunction in schizophrenia and bipolar disorder. Lancet (2003) 4.84
Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus. Diabetes (2004) 4.81
COMT val158met genotype affects mu-opioid neurotransmitter responses to a pain stressor. Science (2003) 4.72
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science (2013) 4.71
Effect of inadequate iodine status in UK pregnant women on cognitive outcomes in their children: results from the Avon Longitudinal Study of Parents and Children (ALSPAC). Lancet (2013) 4.64
Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region. Nat Genet (2009) 4.61
Localization of a type 1 diabetes locus in the IL2RA/CD25 region by use of tag single-nucleotide polymorphisms. Am J Hum Genet (2005) 4.36
Probable person to person transmission of novel avian influenza A (H7N9) virus in Eastern China, 2013: epidemiological investigation. BMJ (2013) 4.17
Obstetric complications and schizophrenia: historical and meta-analytic review. Am J Psychiatry (2002) 4.03
An expanded evaluation of the relationship of four alleles to the level of response to alcohol and the alcoholism risk. Alcohol Clin Exp Res (2005) 3.94
A family cluster of infections by a newly recognized bunyavirus in eastern China, 2007: further evidence of person-to-person transmission. Clin Infect Dis (2011) 3.91
Fish intake during pregnancy and early cognitive development of offspring. Epidemiology (2004) 3.83
Why psychiatry can't afford to be neurophobic. Br J Psychiatry (2009) 3.80
Platelet reactivity and clinical outcomes after coronary artery implantation of drug-eluting stents (ADAPT-DES): a prospective multicentre registry study. Lancet (2013) 3.74
Association of a triallelic serotonin transporter gene promoter region (5-HTTLPR) polymorphism with stressful life events and severity of depression. Am J Psychiatry (2006) 3.44
GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence. Nat Med (2006) 3.38
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet (2010) 3.37
Heterogeneity in incidence rates of schizophrenia and other psychotic syndromes: findings from the 3-center AeSOP study. Arch Gen Psychiatry (2006) 3.35
Coping with out-of-pocket health payments: empirical evidence from 15 African countries. Bull World Health Organ (2008) 3.33
The course of anxiety and depression through pregnancy and the postpartum in a community sample. J Affect Disord (2004) 3.16
New gene functions in megakaryopoiesis and platelet formation. Nature (2011) 3.14
Addictions biology: haplotype-based analysis for 130 candidate genes on a single array. Alcohol Alcohol (2008) 3.13
Genetic variation in LIN28B is associated with the timing of puberty. Nat Genet (2009) 3.09
To retain or remove user fees?: reflections on the current debate in low- and middle-income countries. Appl Health Econ Health Policy (2006) 3.06
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nat Genet (2011) 3.03
Executive subprocesses in working memory: relationship to catechol-O-methyltransferase Val158Met genotype and schizophrenia. Arch Gen Psychiatry (2003) 2.82
Incidence of schizophrenia and other psychoses in ethnic minority groups: results from the MRC AESOP Study. Psychol Med (2006) 2.79
Seventy-five genetic loci influencing the human red blood cell. Nature (2012) 2.77
Catechol-O-methyltransferase gene polymorphisms are associated with multiple pain-evoking stimuli. Pain (2006) 2.75
Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder. Am J Hum Genet (2004) 2.71
Randomized controlled trial of effect of prescription of clozapine versus other second-generation antipsychotic drugs in resistant schizophrenia. Schizophr Bull (2006) 2.71
Early detection and intervention evaluation for people at risk of psychosis: multisite randomised controlled trial. BMJ (2012) 2.70
Genetic variation in human NPY expression affects stress response and emotion. Nature (2008) 2.65
A genome-wide association meta-analysis identifies new childhood obesity loci. Nat Genet (2012) 2.60
A global perspective on genetic variation at the ADH genes reveals unusual patterns of linkage disequilibrium and diversity. Am J Hum Genet (2002) 2.60
Preventing impoverishment through protection against catastrophic health expenditure. Bull World Health Organ (2002) 2.56
A functional polymorphism in the COMT gene and performance on a test of prefrontal cognition. Am J Psychiatry (2002) 2.51
Rearing condition and rh5-HTTLPR interact to influence limbic-hypothalamic-pituitary-adrenal axis response to stress in infant macaques. Biol Psychiatry (2004) 2.49
A 160-kilobit molecular electronic memory patterned at 10(11) bits per square centimetre. Nature (2007) 2.48
Outcomes of conduct problems in adolescence: 40 year follow-up of national cohort. BMJ (2009) 2.47
Strengthening the reporting of genetic association studies (STREGA): an extension of the strengthening the reporting of observational studies in epidemiology (STROBE) statement. J Clin Epidemiol (2009) 2.45
Extrapyramidal motor side-effects of first- and second-generation antipsychotic drugs. Br J Psychiatry (2012) 2.41
Multiple chronic pain states are associated with a common amino acid-changing allele in KCNS1. Brain (2010) 2.41
STrengthening the REporting of Genetic Association Studies (STREGA): an extension of the STROBE statement. PLoS Med (2009) 2.39
The prevalence of symptoms and consultations in pre-school children in the Avon Longitudinal Study of Parents and Children (ALSPAC): a prospective cohort study. Fam Pract (2005) 2.38
Disease-relevant autoantibodies in first episode schizophrenia. J Neurol (2010) 2.33
Incidence of schizophrenia and other psychoses in England, 1950-2009: a systematic review and meta-analyses. PLoS One (2012) 2.33
Effect of a triallelic functional polymorphism of the serotonin-transporter-linked promoter region on expression of serotonin transporter in the human brain. Am J Psychiatry (2006) 2.31
Universal coverage of health services: tailoring its implementation. Bull World Health Organ (2008) 2.30
Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight. Nat Genet (2010) 2.30
Social communication competence and functional adaptation in a general population of children: preliminary evidence for sex-by-verbal IQ differential risk. J Am Acad Child Adolesc Psychiatry (2009) 2.29
Prenatal anxiety predicts individual differences in cortisol in pre-adolescent children. Biol Psychiatry (2005) 2.27
Maternal antenatal anxiety and behavioural/emotional problems in children: a test of a programming hypothesis. J Child Psychol Psychiatry (2003) 2.26
Family history of nocturnal enuresis and urinary incontinence: results from a large epidemiological study. J Urol (2011) 2.22
The alcohol flushing response: an unrecognized risk factor for esophageal cancer from alcohol consumption. PLoS Med (2009) 2.20
The financial burden from non-communicable diseases in low- and middle-income countries: a literature review. Health Res Policy Syst (2013) 2.20
Cannabis and schizophrenia: model projections of the impact of the rise in cannabis use on historical and future trends in schizophrenia in England and Wales. Addiction (2007) 2.20
Genetic influence on variability in human acute experimental pain sensitivity associated with gender, ethnicity and psychological temperament. Pain (2004) 2.17
Psychotic experiences and psychotic disorders at age 18 in relation to psychotic experiences at age 12 in a longitudinal population-based cohort study. Am J Psychiatry (2013) 2.17
Binge pattern of alcohol consumption during pregnancy and childhood mental health outcomes: longitudinal population-based study. Pediatrics (2009) 2.16
Strategies for multiple imputation in longitudinal studies. Am J Epidemiol (2010) 2.15
Association of specific haplotypes of D2 dopamine receptor gene with vulnerability to heroin dependence in 2 distinct populations. Arch Gen Psychiatry (2004) 2.12
Schizophrenia in the offspring of antenatally depressed mothers in the northern Finland 1966 birth cohort: relationship to family history of psychosis. Am J Psychiatry (2009) 2.11
Fetal growth and childhood behavioral problems: results from the ALSPAC cohort. Am J Epidemiol (2006) 2.09
Differential effects of 5-HTTLPR genotypes on the behavioral and neural responses to tryptophan depletion in patients with major depression and controls. Arch Gen Psychiatry (2006) 2.09
A quantitative meta-analysis of population-based studies of premorbid intelligence and schizophrenia. Schizophr Res (2011) 2.09
Cross-national clinical and functional remission rates: Worldwide Schizophrenia Outpatient Health Outcomes (W-SOHO) study. Br J Psychiatry (2011) 2.06
Catechol-O-methyltransferase val158met genotype affects processing of emotional stimuli in the amygdala and prefrontal cortex. J Neurosci (2005) 2.04
A common genetic variant in the 15q24 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) is associated with a reduced ability of women to quit smoking in pregnancy. Hum Mol Genet (2009) 2.02
A population-specific HTR2B stop codon predisposes to severe impulsivity. Nature (2010) 2.00