Published in Neurobiol Aging on January 19, 2007
The Rotterdam Study: 2012 objectives and design update. Eur J Epidemiol (2011) 3.26
Brain structure and obesity. Hum Brain Mapp (2010) 3.04
Midlife vascular risk factor exposure accelerates structural brain aging and cognitive decline. Neurology (2011) 2.91
Neuroanatomical substrates of age-related cognitive decline. Psychol Bull (2011) 2.75
The Rotterdam Study: 2014 objectives and design update. Eur J Epidemiol (2013) 2.56
The Rotterdam Study: 2016 objectives and design update. Eur J Epidemiol (2015) 1.61
Common variants at 6q22 and 17q21 are associated with intracranial volume. Nat Genet (2012) 1.51
Hippocampal atrophy and ventricular enlargement in normal aging, mild cognitive impairment (MCI), and Alzheimer Disease. Alzheimer Dis Assoc Disord (2012) 1.40
Common variants at 12q15 and 12q24 are associated with infant head circumference. Nat Genet (2012) 1.36
Brain tissue volumes in the general population of the elderly: the AGES-Reykjavik study. Neuroimage (2011) 1.28
Causes and consequences of cerebral small vessel disease. The RUN DMC study: a prospective cohort study. Study rationale and protocol. BMC Neurol (2011) 1.13
The Rotterdam Scan Study: design and update up to 2012. Eur J Epidemiol (2011) 1.07
Brain atrophy associations with white matter lesions in the ageing brain: the Lothian Birth Cohort 1936. Eur Radiol (2012) 1.05
Minute effects of sex on the aging brain: a multisample magnetic resonance imaging study of healthy aging and Alzheimer's disease. J Neurosci (2009) 1.01
Beyond mild cognitive impairment: vascular cognitive impairment, no dementia (VCIND). Alzheimers Res Ther (2009) 1.00
Cerebral microbleeds and the risk of mortality in the general population. Eur J Epidemiol (2013) 0.93
MRBrainS Challenge: Online Evaluation Framework for Brain Image Segmentation in 3T MRI Scans. Comput Intell Neurosci (2015) 0.91
Patterns of cognitive function in aging: the Rotterdam Study. Eur J Epidemiol (2014) 0.89
Longitudinal assessment of global and regional rate of grey matter atrophy in 1,172 healthy older adults: modulation by sex and age. PLoS One (2014) 0.88
Genetic architecture of resilience of executive functioning. Brain Imaging Behav (2012) 0.87
The Rotterdam Scan Study: design update 2016 and main findings. Eur J Epidemiol (2015) 0.83
Quantification of optic disc edema during exposure to high altitude shows no correlation to acute mountain sickness. PLoS One (2011) 0.82
Individual differences in fornix microstructure and body mass index. PLoS One (2013) 0.81
Sex-related and tissue-specific effects of tobacco smoking on brain atrophy: assessment in a large longitudinal cohort of healthy elderly. Front Aging Neurosci (2014) 0.80
The influence of cerebral small vessel disease on default mode network deactivation in mild cognitive impairment. Neuroimage Clin (2012) 0.80
Retinal vascular fractals and cognitive impairment. Dement Geriatr Cogn Dis Extra (2014) 0.80
Marked effects of intracranial volume correction methods on sex differences in neuroanatomical structures: a HUNT MRI study. Front Neurosci (2015) 0.80
Global and regional associations of smaller cerebral gray and white matter volumes with gait in older people. PLoS One (2014) 0.79
Kidney Function and Cerebral Blood Flow: The Rotterdam Study. J Am Soc Nephrol (2015) 0.78
Association of change in brain structure to objectively measured physical activity and sedentary behavior in older adults: Age, Gene/Environment Susceptibility-Reykjavik Study. Behav Brain Res (2015) 0.77
IT Infrastructure to support the secondary use of routinely acquired clinical imaging data for research. Neuroinformatics (2015) 0.77
A Review of Risk Factors for Cognitive Impairment in Stroke Survivors. ScientificWorldJournal (2016) 0.75
Prefrontal-Parietal White Matter Volumes in Healthy Elderlies Are Decreased in Proportion to the Degree of Cardiovascular Risk and Related to Inhibitory Control Deficits. Front Psychol (2017) 0.75
Integrated Analysis and Visualization of Group Differences in Structural and Functional Brain Connectivity: Applications in Typical Ageing and Schizophrenia. PLoS One (2015) 0.75
Vascular cognitive impairment: Current concepts and Indian perspective. Ann Indian Acad Neurol (2010) 0.75
Evaluation of a deep learning approach for the segmentation of brain tissues and white matter hyperintensities of presumed vascular origin in MRI. Neuroimage Clin (2017) 0.75
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
A randomized trial of intraarterial treatment for acute ischemic stroke. N Engl J Med (2014) 18.12
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet (2010) 16.96
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet (2011) 13.25
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat Genet (2008) 12.32
Genome-wide association study of blood pressure and hypertension. Nat Genet (2009) 11.54
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet (2012) 11.09
Variants in MTNR1B influence fasting glucose levels. Nat Genet (2008) 10.85
Silent brain infarcts and the risk of dementia and cognitive decline. N Engl J Med (2003) 10.61
Variant of TREM2 associated with the risk of Alzheimer's disease. N Engl J Med (2012) 10.16
Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA (2010) 9.52
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat Genet (2011) 9.23
Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet (2010) 8.89
Incidental findings on brain MRI in the general population. N Engl J Med (2007) 8.59
Large-scale genotyping identifies 41 new loci associated with breast cancer risk. Nat Genet (2013) 8.24
Arterial stiffness and risk of coronary heart disease and stroke: the Rotterdam Study. Circulation (2006) 8.18
Epidemiology of Parkinson's disease. Lancet Neurol (2006) 8.13
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
Host polymorphisms in interleukin 4, complement factor H, and C-reactive protein associated with nasal carriage of Staphylococcus aureus and occurrence of boils. J Infect Dis (2008) 7.45
Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. Nat Genet (2010) 6.49
C-reactive protein, fibrinogen, and cardiovascular disease prediction. N Engl J Med (2012) 6.39
Prevalence, incidence and lifetime risk of atrial fibrillation: the Rotterdam study. Eur Heart J (2006) 6.31
Cerebral microbleeds: a guide to detection and interpretation. Lancet Neurol (2009) 6.02
Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study. Lancet (2008) 5.89
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet (2009) 5.81
The Rotterdam Study: objectives and design update. Eur J Epidemiol (2007) 5.78
New loci associated with kidney function and chronic kidney disease. Nat Genet (2010) 5.58
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet (2012) 5.48
Prolonged QTc interval and risk of sudden cardiac death in a population of older adults. J Am Coll Cardiol (2006) 5.39
Alcohol consumption and risk of dementia: the Rotterdam Study. Lancet (2002) 5.32
Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies. Nat Genet (2009) 5.32
Genomewide association studies of stroke. N Engl J Med (2009) 5.29
Common variants at ten loci influence QT interval duration in the QTGEN Study. Nat Genet (2009) 5.20
Correlation between genetic and geographic structure in Europe. Curr Biol (2008) 5.02
The Study on Cognition and Prognosis in the Elderly (SCOPE): principal results of a randomized double-blind intervention trial. J Hypertens (2003) 4.91
Physical activity, including walking, and cognitive function in older women. JAMA (2004) 4.90
Multiple loci associated with indices of renal function and chronic kidney disease. Nat Genet (2009) 4.78
Silent brain infarcts and white matter lesions increase stroke risk in the general population: the Rotterdam Scan Study. Stroke (2003) 4.78
Plasma Abeta(1-40) and Abeta(1-42) and the risk of dementia: a prospective case-cohort study. Lancet Neurol (2006) 4.77
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet (2012) 4.73
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science (2013) 4.71
High serum uric acid as a novel risk factor for type 2 diabetes. Diabetes Care (2007) 4.69
Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies. Lancet (2012) 4.63
Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function. Nat Genet (2009) 4.56
Lipoprotein-associated phospholipase A(2) and risk of coronary disease, stroke, and mortality: collaborative analysis of 32 prospective studies. Lancet (2010) 4.46
Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis. Nat Genet (2009) 4.38
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet (2012) 4.37
Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. Nat Genet (2009) 4.28
Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size. PLoS Genet (2009) 4.24
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet (2014) 4.13
Dietary intake of antioxidants and risk of Alzheimer disease. JAMA (2002) 4.01
Common variants in KCNN3 are associated with lone atrial fibrillation. Nat Genet (2010) 3.97
Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children. PLoS Med (2011) 3.94
Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies. Lancet Neurol (2012) 3.93
Lipid-related markers and cardiovascular disease prediction. JAMA (2012) 3.91
Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry. Nat Genet (2009) 3.80
Genome-wide association study of PR interval. Nat Genet (2010) 3.73
Identification of common variants associated with human hippocampal and intracranial volumes. Nat Genet (2012) 3.73
Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Nat Genet (2012) 3.71
Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation (2011) 3.68
Common carotid intima-media thickness measurements in cardiovascular risk prediction: a meta-analysis. JAMA (2012) 3.67
Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. Nat Genet (2010) 3.55
Predicting type 2 diabetes based on polymorphisms from genome-wide association studies: a population-based study. Diabetes (2008) 3.54
Quantifying the heart failure epidemic: prevalence, incidence rate, lifetime risk and prognosis of heart failure The Rotterdam Study. Eur Heart J (2004) 3.52
The Rotterdam Study: 2010 objectives and design update. Eur J Epidemiol (2009) 3.44
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet (2011) 3.40
Inflammatory proteins in plasma and the risk of dementia: the rotterdam study. Arch Neurol (2004) 3.38
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet (2010) 3.37
New ischaemic brain lesions on MRI after stenting or endarterectomy for symptomatic carotid stenosis: a substudy of the International Carotid Stenting Study (ICSS). Lancet Neurol (2010) 3.35
Cerebral small-vessel disease and decline in information processing speed, executive function and memory. Brain (2005) 3.34
Homocysteine levels and the risk of osteoporotic fracture. N Engl J Med (2004) 3.32
Coronary calcification improves cardiovascular risk prediction in the elderly. Circulation (2005) 3.28
Corticosteroids and the risk of atrial fibrillation. Arch Intern Med (2006) 3.28
The Rotterdam Study: 2012 objectives and design update. Eur J Epidemiol (2011) 3.26
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet (2013) 3.25
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Incidence and prognosis of transient neurological attacks. JAMA (2007) 3.21
Measuring cognitive function with age: the influence of selection by health and survival. Epidemiology (2008) 3.19
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nat Genet (2011) 3.18