Published in Transplantation on January 27, 2007
Hepatic function after genetically engineered pig liver transplantation in baboons. Transplantation (2010) 1.64
Single nucleotide polymorphisms (SNPs) are highly conserved in rhesus (Macaca mulatta) and cynomolgus (Macaca fascicularis) macaques. BMC Genomics (2007) 1.13
Dissecting the instant blood-mediated inflammatory reaction in islet xenotransplantation. Xenotransplantation (2008) 1.12
Islet xenotransplantation using gal-deficient neonatal donors improves engraftment and function. Am J Transplant (2011) 1.06
Overcoming the barriers to xenotransplantation: prospects for the future. Expert Rev Clin Immunol (2010) 0.99
Pig-to-monkey islet xenotransplantation using multi-transgenic pigs. Am J Transplant (2014) 0.96
Innate immunity and heat shock response in islet transplantation. Clin Exp Immunol (2009) 0.86
Pig-to-nonhuman primates pancreatic islet xenotransplantation: an overview. Curr Diab Rep (2011) 0.86
Dual islet transplantation modeling of the instant blood-mediated inflammatory reaction. Am J Transplant (2015) 0.78
A syndrome of severe hypoglycemia and acidosis in young immunosuppressed diabetic monkeys and pigs-association with sepsis. Transplantation (2012) 0.78
Islet cell xenotransplantation: a serious look toward the clinic. Xenotransplantation (2014) 0.78
Glucose-regulated insulin production in the liver improves glycemic control in type 1 diabetic mice. Mol Metab (2014) 0.77
Frankenswine, or bringing home the bacon: How close are we to clinical trials in xenotransplantation? Organogenesis (2008) 0.75
Tolerogenic immunosuppression for organ transplantation. Lancet (2003) 4.09
Production of alpha 1,3-galactosyltransferase-deficient pigs. Science (2002) 3.96
On the use of general control samples for genome-wide association studies: genetic matching highlights causal variants. Am J Hum Genet (2008) 3.95
Alpha1,3-galactosyltransferase gene-knockout pigs for xenotransplantation: where do we go from here? Transplantation (2007) 3.65
Heart transplantation in baboons using alpha1,3-galactosyltransferase gene-knockout pigs as donors: initial experience. Nat Med (2004) 3.58
Polycomb protein Ezh2 regulates pancreatic beta-cell Ink4a/Arf expression and regeneration in diabetes mellitus. Genes Dev (2009) 3.02
Carbon monoxide differentially inhibits TLR signaling pathways by regulating ROS-induced trafficking of TLRs to lipid rafts. J Exp Med (2006) 2.77
Screen and clean: a tool for identifying interactions in genome-wide association studies. Genet Epidemiol (2010) 2.70
Acute rejection is associated with antibodies to non-Gal antigens in baboons using Gal-knockout pig kidneys. Nat Med (2005) 2.67
PDGF signalling controls age-dependent proliferation in pancreatic β-cells. Nature (2011) 2.53
A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene. Clin Immunol (2007) 2.23
Response of human islets to isolation stress and the effect of antioxidant treatment. Diabetes (2004) 2.16
Factors associated with islet yield and insulin independence after total pancreatectomy and islet cell autotransplantation in patients with chronic pancreatitis utilizing off-site islet isolation: Cleveland Clinic experience. J Clin Endocrinol Metab (2015) 2.14
Potent induction immunotherapy promotes long-term insulin independence after islet transplantation in type 1 diabetes. Am J Transplant (2012) 2.12
Total pancreatectomy and islet autotransplantation for chronic pancreatitis. J Am Coll Surg (2012) 2.00
Kidney transplantation under minimal immunosuppression after pretransplant lymphoid depletion with Thymoglobulin or Campath. J Am Coll Surg (2005) 1.93
Quality of life improves for pediatric patients after total pancreatectomy and islet autotransplant for chronic pancreatitis. Clin Gastroenterol Hepatol (2011) 1.93
Clinical xenotransplantation: the next medical revolution? Lancet (2011) 1.84
Induction of beta-cell proliferation and retinoblastoma protein phosphorylation in rat and human islets using adenovirus-mediated transfer of cyclin-dependent kinase-4 and cyclin D1. Diabetes (2004) 1.81
Selected physiologic compatibilities and incompatibilities between human and porcine organ systems. Xenotransplantation (2006) 1.81
Islet autotransplant outcomes after total pancreatectomy: a contrast to islet allograft outcomes. Transplantation (2008) 1.80
Neonatal β cell development in mice and humans is regulated by calcineurin/NFAT. Dev Cell (2012) 1.72
Thymus-specific deletion of insulin induces autoimmune diabetes. EMBO J (2009) 1.70
Liver-specific deletion of the growth hormone receptor reveals essential role of growth hormone signaling in hepatic lipid metabolism. J Biol Chem (2009) 1.69
Prolonged insulin independence after islet allotransplants in recipients with type 1 diabetes. Am J Transplant (2008) 1.68
Phase I (safety) study of autologous tolerogenic dendritic cells in type 1 diabetic patients. Diabetes Care (2011) 1.65
Hepatic function after genetically engineered pig liver transplantation in baboons. Transplantation (2010) 1.64
Cytoplasmic islet cell antibodies remain valuable in defining risk of progression to type 1 diabetes in subjects with other islet autoantibodies. Pediatr Diabetes (2005) 1.64
Monocytes are progressively activated in the circulation of pregnant women. J Leukoc Biol (2002) 1.63
Immunosuppression for liver transplantation in HCV-infected patients: mechanism-based principles. Liver Transpl (2005) 1.61
Long-term survival, nutritional autonomy, and quality of life after intestinal and multivisceral transplantation. Ann Surg (2012) 1.59
HLA-A*0201-restricted T cells from humanized NOD mice recognize autoantigens of potential clinical relevance to type 1 diabetes. J Immunol (2006) 1.58
alpha1,3-Galactosyltransferase gene-knockout pig heart transplantation in baboons with survival approaching 6 months. Transplantation (2005) 1.56
Kidney transplantation under a tolerogenic regimen of recipient pretreatment and low-dose postoperative immunosuppression with subsequent weaning. Ann Surg (2003) 1.52
Toward a cure for type 1 diabetes mellitus: diabetes-suppressive dendritic cells and beyond. Pediatr Diabetes (2008) 1.50
Sirolimus is associated with reduced islet engraftment and impaired beta-cell function. Diabetes (2006) 1.49
Investigation of red blood cells from alpha1,3-galactosyltransferase-knockout pigs for human blood transfusion. Transfusion (2004) 1.48
The innate immune response and activation of coagulation in alpha1,3-galactosyltransferase gene-knockout xenograft recipients. Transplantation (2009) 1.47
Carbon monoxide inhalation protects rat intestinal grafts from ischemia/reperfusion injury. Am J Pathol (2003) 1.47
Xenogeneic thymus transplantation in a pig-to-baboon model. Transplantation (2003) 1.47
Functionally important glycosyltransferase gain and loss during catarrhine primate emergence. Proc Natl Acad Sci U S A (2006) 1.46
Widespread and stable pancreatic gene transfer by adeno-associated virus vectors via different routes. Diabetes (2006) 1.45
In vitro investigation of pig cells for resistance to human antibody-mediated rejection. Transpl Int (2008) 1.44
Use of alemtuzumab and tacrolimus monotherapy for cadaveric liver transplantation: with particular reference to hepatitis C virus. Transplantation (2004) 1.43
Biliverdin protects the functional integrity of a transplanted syngeneic small bowel. Gastroenterology (2004) 1.39
Identification of novel IGRP epitopes targeted in type 1 diabetes patients. Clin Immunol (2008) 1.38
Thrombotic microangiopathy associated with humoral rejection of cardiac xenografts from alpha1,3-galactosyltransferase gene-knockout pigs in baboons. Am J Pathol (2008) 1.36
Protection against ischemia/reperfusion injury in cardiac and renal transplantation with carbon monoxide, biliverdin and both. Am J Transplant (2005) 1.36
Protection of transplant-induced renal ischemia-reperfusion injury with carbon monoxide. Am J Physiol Renal Physiol (2004) 1.33
Caveolin-1 expression by means of p38beta mitogen-activated protein kinase mediates the antiproliferative effect of carbon monoxide. Proc Natl Acad Sci U S A (2005) 1.29
Gene transfer of constitutively active Akt markedly improves human islet transplant outcomes in diabetic severe combined immunodeficient mice. Diabetes (2005) 1.27
Clinical islet xenotransplantation: how close are we? Diabetes (2012) 1.26
Thrombotic microangiopathy and graft arteriopathy in pig hearts following transplantation into baboons. Xenotransplantation (2004) 1.26
Prospective and challenges of islet transplantation for the therapy of autoimmune diabetes. Pancreas (2006) 1.25
Indoleamine 2,3-dioxygenase expression in transplanted NOD Islets prolongs graft survival after adoptive transfer of diabetogenic splenocytes. Diabetes (2002) 1.23
Five hundred intestinal and multivisceral transplantations at a single center: major advances with new challenges. Ann Surg (2009) 1.21
Toll-like receptor 4 mediates the early inflammatory response after cold ischemia/reperfusion. Transplantation (2007) 1.21
Reactive oxygen species production by forward and reverse electron fluxes in the mitochondrial respiratory chain. PLoS Comput Biol (2011) 1.21
Rapid loss of intraportally transplanted islets: an overview of pathophysiology and preventive strategies. Xenotransplantation (2007) 1.20
Disruption of innate-mediated proinflammatory cytokine and reactive oxygen species third signal leads to antigen-specific hyporesponsiveness. J Immunol (2007) 1.19
Ethyl pyruvate ameliorates liver ischemia-reperfusion injury by decreasing hepatic necrosis and apoptosis. Transplantation (2005) 1.19
Role of NF-kappaB on liver cold ischemia-reperfusion injury. Am J Physiol Gastrointest Liver Physiol (2002) 1.19
Metabolic aspects of pig-to-monkey (Macaca fascicularis) islet transplantation: implications for translation into clinical practice. Diabetologia (2007) 1.19
Protective effect of carbon monoxide in transplantation. J Cell Mol Med (2006) 1.19
Expansion and conversion of human pancreatic ductal cells into insulin-secreting endocrine cells. Elife (2013) 1.19
Human islet isolation for autologous transplantation: comparison of yield and function using SERVA/Nordmark versus Roche enzymes. Am J Transplant (2009) 1.18
Molecular basis of evolutionary loss of the alpha 1,3-galactosyltransferase gene in higher primates. J Biol Chem (2001) 1.18
Preservation of human islet cell functional mass by anti-oxidative action of a novel SOD mimic compound. Diabetes (2002) 1.17
Coagulation dysregulation as a barrier to xenotransplantation in the primate. Transpl Immunol (2008) 1.17
Suppression of natural and elicited antibodies in pig-to-baboon heart transplantation using a human anti-human CD154 mAb-based regimen. Am J Transplant (2004) 1.17
Prediction of pancreatic tissue densities by an analytical test gradient system before purification maximizes human islet recovery for islet autotransplantation/allotransplantation. Transplantation (2011) 1.17
Hormonal therapy of the brain-dead organ donor: experimental and clinical studies. Transplantation (2006) 1.17
The choice of anatomical site for islet transplantation. Cell Transplant (2008) 1.17
Human proinsulin C-peptide reduces high glucose-induced proliferation and NF-kappaB activation in vascular smooth muscle cells. Atherosclerosis (2008) 1.17
Antisense oligonucleotides down-regulating costimulation confer diabetes-preventive properties to nonobese diabetic mouse dendritic cells. J Immunol (2004) 1.16
Clinical lung xenotransplantation--what donor genetic modifications may be necessary? Xenotransplantation (2012) 1.16
Current status of xenotransplantation and prospects for clinical application. Xenotransplantation (2009) 1.15