Published in Trends Biochem Sci on March 09, 2007
miR-145 and miR-143 regulate smooth muscle cell fate and plasticity. Nature (2009) 10.26
SMAD proteins control DROSHA-mediated microRNA maturation. Nature (2008) 9.67
miR-126 regulates angiogenic signaling and vascular integrity. Dev Cell (2008) 6.59
MicroRNA regulation of cell lineages in mouse and human embryonic stem cells. Cell Stem Cell (2008) 4.70
miR-212 and miR-132 are required for epithelial stromal interactions necessary for mouse mammary gland development. Nat Genet (2010) 4.06
Antagomir-17-5p abolishes the growth of therapy-resistant neuroblastoma through p21 and BIM. PLoS One (2008) 3.68
Biological functions of miR-29b contribute to positive regulation of osteoblast differentiation. J Biol Chem (2009) 3.62
A microRNA signature for a BMP2-induced osteoblast lineage commitment program. Proc Natl Acad Sci U S A (2008) 3.29
MicroRNA-9 coordinates proliferation and migration of human embryonic stem cell-derived neural progenitors. Cell Stem Cell (2010) 3.18
MicroRNAs and their target gene networks in breast cancer. Breast Cancer Res (2010) 2.83
Induction of microRNA-221 by platelet-derived growth factor signaling is critical for modulation of vascular smooth muscle phenotype. J Biol Chem (2008) 2.81
Role of MicroRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells. Biochem Pharmacol (2008) 2.56
Transforming growth factor-beta-regulated miR-24 promotes skeletal muscle differentiation. Nucleic Acids Res (2008) 2.44
MicroRNA regulation of cardiovascular development. Circ Res (2009) 2.42
The RNA-binding proteins HYL1 and SE promote accurate in vitro processing of pri-miRNA by DCL1. Proc Natl Acad Sci U S A (2008) 2.40
Multilevel regulation of gene expression by microRNAs. Science (2008) 2.28
A human cytomegalovirus-encoded microRNA regulates expression of multiple viral genes involved in replication. PLoS Pathog (2007) 2.26
miR-24 inhibits apoptosis and represses Bim in mouse cardiomyocytes. J Exp Med (2011) 2.24
Expansion of intronic GGCCTG hexanucleotide repeat in NOP56 causes SCA36, a type of spinocerebellar ataxia accompanied by motor neuron involvement. Am J Hum Genet (2011) 2.19
The microRNA-30 family is required for vertebrate hepatobiliary development. Gastroenterology (2008) 2.17
Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cells. Autophagy (2009) 2.09
The miR-29 family: genomics, cell biology, and relevance to renal and cardiovascular injury. Physiol Genomics (2012) 2.08
MicroRNA profiling identifies miR-34a and miR-21 and their target genes JAG1 and WNT1 in the coordinate regulation of dendritic cell differentiation. Blood (2009) 2.07
Regulated expression of microRNAs in normal and polycythemia vera erythropoiesis. Exp Hematol (2007) 1.98
MicroRNA profile changes in human immunodeficiency virus type 1 (HIV-1) seropositive individuals. Retrovirology (2008) 1.96
Regulation of eukaryotic gene expression by the untranslated gene regions and other non-coding elements. Cell Mol Life Sci (2012) 1.96
Epstein-Barr virus-induced miR-155 attenuates NF-kappaB signaling and stabilizes latent virus persistence. J Virol (2008) 1.86
microRNA-138 modulates cardiac patterning during embryonic development. Proc Natl Acad Sci U S A (2008) 1.80
Diverse set of microRNAs are responsive to powdery mildew infection and heat stress in wheat (Triticum aestivum L.). BMC Plant Biol (2010) 1.80
miRNAs regulate SIRT1 expression during mouse embryonic stem cell differentiation and in adult mouse tissues. Aging (Albany NY) (2010) 1.76
microRNAs and muscle disorders. J Cell Sci (2009) 1.73
Post-transcriptional control of DGCR8 expression by the Microprocessor. RNA (2009) 1.67
The roles of microRNAs in mammalian virus infection. Biochim Biophys Acta (2008) 1.64
Characterization of microRNAs involved in embryonic stem cell states. Stem Cells Dev (2010) 1.62
MicroRNA-663 upregulated by oscillatory shear stress plays a role in inflammatory response of endothelial cells. Am J Physiol Heart Circ Physiol (2011) 1.59
MicroRNAs: opening a new vein in angiogenesis research. Sci Signal (2009) 1.58
MAGIA, a web-based tool for miRNA and Genes Integrated Analysis. Nucleic Acids Res (2010) 1.58
Posttranscriptional control of neuronal development by microRNA networks. Trends Neurosci (2007) 1.56
miR-204 is required for lens and retinal development via Meis2 targeting. Proc Natl Acad Sci U S A (2010) 1.48
Emerging roles of microRNAs in the control of embryonic stem cells and the generation of induced pluripotent stem cells. Dev Biol (2010) 1.47
Ancora: a web resource for exploring highly conserved noncoding elements and their association with developmental regulatory genes. Genome Biol (2008) 1.46
Enhanced Cardiac Regenerative Ability of Stem Cells After Ischemia-Reperfusion Injury: Role of Human CD34(+) Cells Deficient in MicroRNA-377. J Am Coll Cardiol (2015) 1.45
BANF1 is downregulated by IRF1-regulated microRNA-203 in cervical cancer. PLoS One (2015) 1.44
miR-1-mediated induction of cardiogenesis in mesenchymal stem cells via downregulation of Hes-1. Biomed Res Int (2012) 1.44
ICF, an immunodeficiency syndrome: DNA methyltransferase 3B involvement, chromosome anomalies, and gene dysregulation. Autoimmunity (2008) 1.43
MicroRNA expression and regulation in human, chimpanzee, and macaque brains. PLoS Genet (2011) 1.40
MicroRNAs in skeletal muscle: their role and regulation in development, disease and function. J Physiol (2010) 1.33
miRNA expression profiling of 51 human breast cancer cell lines reveals subtype and driver mutation-specific miRNAs. Breast Cancer Res (2013) 1.29
Identifying functional miRNA-mRNA regulatory modules with correspondence latent dirichlet allocation. Bioinformatics (2010) 1.28
Solexa sequencing of novel and differentially expressed microRNAs in testicular and ovarian tissues in Holstein cattle. Int J Biol Sci (2011) 1.26
Characterizing the role of miRNAs within gene regulatory networks using integrative genomics techniques. Mol Syst Biol (2011) 1.25
The functions of microRNAs in pluripotency and reprogramming. Nat Cell Biol (2012) 1.23
miRNA-transcription factor interactions: a combinatorial regulation of gene expression. Mol Genet Genomics (2013) 1.21
Identification of the receptor tyrosine kinase AXL in breast cancer as a target for the human miR-34a microRNA. Breast Cancer Res Treat (2011) 1.19
Dicer is required for survival of differentiating neural crest cells. Dev Biol (2010) 1.19
miR-145 directs intestinal maturation in zebrafish. Proc Natl Acad Sci U S A (2009) 1.19
MiR-155 promotes proliferation of human breast cancer MCF-7 cells through targeting tumor protein 53-induced nuclear protein 1. J Biomed Sci (2013) 1.18
MiR-101 is involved in human breast carcinogenesis by targeting Stathmin1. PLoS One (2012) 1.17
MicroRNAs in cancer treatment and prognosis. Am J Cancer Res (2012) 1.17
Epithelial progenitor cells of the embryonic lung and the role of microRNAs in their proliferation. Proc Am Thorac Soc (2008) 1.16
miR-31 functions as a negative regulator of lymphatic vascular lineage-specific differentiation in vitro and vascular development in vivo. Mol Cell Biol (2010) 1.15
Epigenetic modulation of miR-122 facilitates human embryonic stem cell self-renewal and hepatocellular carcinoma proliferation. PLoS One (2011) 1.11
Human papillomaviruses modulate microRNA 145 expression to directly control genome amplification. J Virol (2013) 1.09
Dynamic landscape of tandem 3' UTRs during zebrafish development. Genome Res (2012) 1.09
Cardiac differentiation of pluripotent stem cells. Stem Cells Int (2011) 1.09
MicroRNA-22 increases senescence and activates cardiac fibroblasts in the aging heart. Age (Dordr) (2012) 1.06
Mega roles of microRNAs in regulation of skeletal muscle health and disease. Front Physiol (2014) 1.03
Hand factors as regulators of cardiac morphogenesis and implications for congenital heart defects. Birth Defects Res A Clin Mol Teratol (2011) 1.03
microRNAs: key triggers of neuronal cell fate. Front Cell Neurosci (2014) 1.02
A novel onco-miR-365 induces cutaneous squamous cell carcinoma. Carcinogenesis (2013) 1.01
MicroRNAs in cardiac development. Pediatr Cardiol (2010) 1.01
Multi-modal strategies for overcoming tumor drug resistance: hypoxia, the Warburg effect, stem cells, and multifunctional nanotechnology. J Control Release (2011) 1.01
Retracted The expression and ovarian steroid regulation of endometrial micro-RNAs. Reprod Sci (2008) 1.00
MicroRNA 4423 is a primate-specific regulator of airway epithelial cell differentiation and lung carcinogenesis. Proc Natl Acad Sci U S A (2013) 1.00
Overexpression of miR-30b in the developing mouse mammary gland causes a lactation defect and delays involution. PLoS One (2012) 0.99
Post-transcriptional regulation of mouse mu opioid receptor (MOR1) via its 3' untranslated region: a role for microRNA23b. FASEB J (2008) 0.98
Targeted deletion of Dicer disrupts lens morphogenesis, corneal epithelium stratification, and whole eye development. Dev Dyn (2009) 0.98
microRNAs: tiny regulators of synapse function in development and disease. J Cell Mol Med (2008) 0.98
MicroRNA-17-3p is a prostate tumor suppressor in vitro and in vivo, and is decreased in high grade prostate tumors analyzed by laser capture microdissection. Clin Exp Metastasis (2009) 0.97
The role of human Dicer-dsRBD in processing small regulatory RNAs. PLoS One (2012) 0.97
MicroRNAs, development of Barrett's esophagus, and progression to esophageal adenocarcinoma. World J Gastroenterol (2010) 0.95
MicroRNA-processing enzyme Dicer is required in epicardium for coronary vasculature development. J Biol Chem (2011) 0.95
Discriminating single-base difference miRNA expressions using microarray Probe Design Guru (ProDeG). Nucleic Acids Res (2008) 0.95
Transcriptional control of microRNA expression in C. elegans: promoting better understanding. RNA Biol (2009) 0.94
Different miRNA expression profiles between human breast cancer tumors and serum. Front Genet (2014) 0.94
Down-regulation of some miRNAs by degrading their precursors contributes to anti-cancer effect of mistletoe lectin-I. Br J Pharmacol (2011) 0.93
Human cytomegalovirus clinical strain-specific microRNA miR-UL148D targets the human chemokine RANTES during infection. PLoS Pathog (2012) 0.93
Transgenic overexpression of miR-133a in skeletal muscle. BMC Musculoskelet Disord (2011) 0.93
MicroRNAs - Biology and clinical applications. J Oral Maxillofac Pathol (2014) 0.93
Dynamic origins of differential RNA binding function in two dsRBDs from the miRNA "microprocessor" complex. Biochemistry (2010) 0.92
Disease-linked microRNA-21 exhibits drastically reduced mRNA binding and silencing activity in healthy mouse liver. RNA (2012) 0.92
Impact of host genes and strand selection on miRNA and miRNA* expression. PLoS One (2011) 0.92
Mechanism of human Hb switching: a possible role of the kit receptor/miR 221-222 complex. Haematologica (2010) 0.91
Circulating microRNAs: promising candidates serving as novel biomarkers of acute hepatitis. Front Physiol (2012) 0.90
Entrapment neuropathy results in different microRNA expression patterns from denervation injury in rats. BMC Musculoskelet Disord (2010) 0.90
Embryonic stem cell-derived microvesicles induce gene expression changes in Müller cells of the retina. PLoS One (2012) 0.90
MicroRNAs: Potential biomarkers in cancer. Indian J Clin Biochem (2010) 0.89
Dicer activity in neural crest cells is essential for craniofacial organogenesis and pharyngeal arch artery morphogenesis. Mech Dev (2011) 0.89
MiR-20a promotes cervical cancer proliferation and metastasis in vitro and in vivo. PLoS One (2015) 0.89
Multiple tumor suppressor microRNAs regulate telomerase and TCF7, an important transcriptional regulator of the Wnt pathway. PLoS One (2014) 0.89
Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis. Nature (2005) 17.17
Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. Cell (2010) 15.58
Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2. Cell (2007) 12.72
miR-145 and miR-143 regulate smooth muscle cell fate and plasticity. Nature (2009) 10.26
In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes. Nature (2012) 7.80
miR-126 regulates angiogenic signaling and vascular integrity. Dev Cell (2008) 6.59
GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5. Nature (2003) 6.40
Mutations in NOTCH1 cause aortic valve disease. Nature (2005) 6.27
Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair. Nature (2004) 4.97
MicroRNA regulation of cell lineages in mouse and human embryonic stem cells. Cell Stem Cell (2008) 4.70
Dynamic and coordinated epigenetic regulation of developmental transitions in the cardiac lineage. Cell (2012) 4.22
Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling. Dev Cell (2009) 4.21
MicroRNA1 influences cardiac differentiation in Drosophila and regulates Notch signaling. Proc Natl Acad Sci U S A (2005) 3.78
The Hand1 and Hand2 transcription factors regulate expansion of the embryonic cardiac ventricles in a gene dosage-dependent manner. Development (2004) 2.61
MicroRNAs as regulators of differentiation and cell fate decisions. Cell Stem Cell (2010) 2.57
Canonical Wnt signaling is a positive regulator of mammalian cardiac progenitors. Proc Natl Acad Sci U S A (2007) 2.56
The antiproliferative action of progesterone in uterine epithelium is mediated by Hand2. Science (2011) 2.46
MicroRNA regulation of cardiovascular development. Circ Res (2009) 2.42
Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis. Nat Genet (2002) 2.27
miR-24 inhibits apoptosis and represses Bim in mouse cardiomyocytes. J Exp Med (2011) 2.24
The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient. Cell (2005) 2.19
Direct reprogramming of human fibroblasts toward a cardiomyocyte-like state. Stem Cell Reports (2013) 2.05
Tbx1 is regulated by tissue-specific forkhead proteins through a common Sonic hedgehog-responsive enhancer. Genes Dev (2003) 2.01
Genetics of human cardiovascular disease. Cell (2012) 1.90
Thymosin beta4 mediated PKC activation is essential to initiate the embryonic coronary developmental program and epicardial progenitor cell activation in adult mice in vivo. J Mol Cell Cardiol (2009) 1.88
microRNA-138 modulates cardiac patterning during embryonic development. Proc Natl Acad Sci U S A (2008) 1.80
Tbx1 regulates fibroblast growth factors in the anterior heart field through a reinforcing autoregulatory loop involving forkhead transcription factors. Development (2004) 1.75
A regulatory pathway involving Notch1/beta-catenin/Isl1 determines cardiac progenitor cell fate. Nat Cell Biol (2009) 1.73
Spectrum of heart disease associated with murine and human GATA4 mutation. J Mol Cell Cardiol (2007) 1.71
Stromal cell-derived factor-1alpha is cardioprotective after myocardial infarction. Circulation (2008) 1.68
Notch post-translationally regulates β-catenin protein in stem and progenitor cells. Nat Cell Biol (2011) 1.66
A resource for the conditional ablation of microRNAs in the mouse. Cell Rep (2012) 1.66
Chromosomal haplotypes by genetic phasing of human families. Am J Hum Genet (2011) 1.58
MicroRNAs: opening a new vein in angiogenesis research. Sci Signal (2009) 1.58
MicroRNA-10 regulates the angiogenic behavior of zebrafish and human endothelial cells by promoting vascular endothelial growth factor signaling. Circ Res (2012) 1.56
Pbx1/Pbx2 requirement for distal limb patterning is mediated by the hierarchical control of Hox gene spatial distribution and Shh expression. Development (2006) 1.56
Cooperative and antagonistic interactions between Sall4 and Tbx5 pattern the mouse limb and heart. Nat Genet (2005) 1.47
Ephrin-B2 reverse signaling is required for axon pathfinding and cardiac valve formation but not early vascular development. Dev Biol (2004) 1.47
Essential roles of the bHLH transcription factor Hrt2 in repression of atrial gene expression and maintenance of postnatal cardiac function. Proc Natl Acad Sci U S A (2007) 1.42
Serum response factor orchestrates nascent sarcomerogenesis and silences the biomineralization gene program in the heart. Proc Natl Acad Sci U S A (2008) 1.39
Alternative induced pluripotent stem cell characterization criteria for in vitro applications. Cell Stem Cell (2009) 1.36
Derivation conditions impact X-inactivation status in female human induced pluripotent stem cells. Cell Stem Cell (2012) 1.35
Notch1 represses osteogenic pathways in aortic valve cells. J Mol Cell Cardiol (2009) 1.32
Reprogramming of mouse fibroblasts into cardiomyocyte-like cells in vitro. Nat Protoc (2013) 1.31
A Slit/miR-218/Robo regulatory loop is required during heart tube formation in zebrafish. Development (2011) 1.31
Interaction of Gata4 and Gata6 with Tbx5 is critical for normal cardiac development. Dev Biol (2008) 1.29
Limited gene expression variation in human embryonic stem cell and induced pluripotent stem cell-derived endothelial cells. Stem Cells (2013) 1.29
Elevated miR-499 levels blunt the cardiac stress response. PLoS One (2011) 1.28
Hairy-related transcription factors inhibit GATA-dependent cardiac gene expression through a signal-responsive mechanism. J Biol Chem (2004) 1.24
Hypoxic repression of endothelial nitric-oxide synthase transcription is coupled with eviction of promoter histones. J Biol Chem (2009) 1.20
The paradoxical patent ductus arteriosus. J Clin Invest (2006) 1.18
microRNA-1 regulates sarcomere formation and suppresses smooth muscle gene expression in the mammalian heart. Elife (2013) 1.18
Endotoxin-induced cardiomyopathy and systemic inflammation in mice is prevented by aldose reductase inhibition. Circulation (2006) 1.17
Unraveling the genetic and developmental mysteries of 22q11 deletion syndrome. Trends Mol Med (2003) 1.16
Screening and biochemical analysis of GATA4 sequence variations identified in patients with congenital heart disease. Am J Med Genet A (2007) 1.13
Critical factors for cardiac reprogramming. Circ Res (2012) 1.12
Identification of GATA6 sequence variants in patients with congenital heart defects. Pediatr Res (2010) 1.10
Altered microRNAs in bicuspid aortic valve: a comparison between stenotic and insufficient valves. J Heart Valve Dis (2010) 1.10
Stem cell therapy for cardiac disease. Pediatr Res (2012) 1.10
Japanese encephalitis (JE). Part I: clinical profile of 1,282 adult acute cases of four epidemics. J Neurol (2011) 1.07
Wnt/beta-catenin signaling acts at multiple developmental stages to promote mammalian cardiogenesis. Cell Cycle (2008) 1.05
Reporter-based isolation of induced pluripotent stem cell- and embryonic stem cell-derived cardiac progenitors reveals limited gene expression variance. Circ Res (2010) 1.04
Congenital heart disease-causing Gata4 mutation displays functional deficits in vivo. PLoS Genet (2012) 1.03
The chemokine receptor CXCR7 functions to regulate cardiac valve remodeling. Dev Dyn (2011) 1.03
Direct cardiac reprogramming: from developmental biology to cardiac regeneration. Circ Res (2013) 1.02
Galphaq and Galpha11 proteins mediate endothelin-1 signaling in neural crest-derived pharyngeal arch mesenchyme. Dev Biol (2003) 1.01
MicroRNAs in cardiac development. Pediatr Cardiol (2010) 1.01
Hrt and Hes negatively regulate Notch signaling through interactions with RBP-Jkappa. Biochem Biophys Res Commun (2006) 1.01
The genetics of cardiac birth defects. Semin Cell Dev Biol (2006) 0.99
Hand2 function in second heart field progenitors is essential for cardiogenesis. Dev Biol (2010) 0.99
Theory of transport of long polymer molecules through carbon nanotube channels. Phys Rev Lett (2003) 0.99
Transcriptional regulation during development of the ductus arteriosus. Circ Res (2008) 0.96
Fibronectin mediates mesendodermal cell fate decisions. Development (2013) 0.95
Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species. J Cell Biol (2011) 0.95
The neural crest-enriched microRNA miR-452 regulates epithelial-mesenchymal signaling in the first pharyngeal arch. Development (2010) 0.94
A genome-wide screen reveals a role for microRNA-1 in modulating cardiac cell polarity. Dev Cell (2011) 0.93
Tbx1 regulates oral epithelial adhesion and palatal development. Hum Mol Genet (2012) 0.93
Tbx1 is regulated by forkhead proteins in the secondary heart field. Dev Dyn (2006) 0.92
Sonic hedgehog is essential for first pharyngeal arch development. Pediatr Res (2006) 0.92
skNAC, a Smyd1-interacting transcription factor, is involved in cardiac development and skeletal muscle growth and regeneration. Proc Natl Acad Sci U S A (2010) 0.92
AKAP13 Rho-GEF and PKD-binding domain deficient mice develop normally but have an abnormal response to β-adrenergic-induced cardiac hypertrophy. PLoS One (2013) 0.88
A role for RNA post-transcriptional regulation in satellite cell activation. Skelet Muscle (2012) 0.88
Thermal conductivity in thin silicon nanowires: phonon confinement effect. Nano Lett (2007) 0.86
Japanese encephalitis (JE) part II: 14 years' follow-up of survivors. J Neurol (2011) 0.85
Congenital heart disease: entering a new era of human genetics. Circ Res (2014) 0.84
Vertebrate heart growth is regulated by functional antagonism between Gridlock and Gata5. Proc Natl Acad Sci U S A (2007) 0.84
Direct reprogramming of fibroblasts into cardiomyocytes for cardiac regenerative medicine. Circ J (2015) 0.83
Loss of Apaf-1 leads to partial rescue of the HAND2-null phenotype. Dev Biol (2005) 0.83
Carbon nanotube "T Junctions": formation pathways and conductivity. Phys Rev Lett (2003) 0.83
Thymosin beta4 and cardiac repair. Ann N Y Acad Sci (2010) 0.83
Tooth-type specific expression of dHAND/Hand2: possible involvement in murine lower incisor morphogenesis. Cell Tissue Res (2002) 0.82
Functional attenuation of UFD1l, a 22q11.2 deletion syndrome candidate gene, leads to cardiac outflow septation defects in chicken embryos. Pediatr Res (2003) 0.81
Molecular dynamics simulations of carbon nanotube/silicon interfacial thermal conductance. J Chem Phys (2008) 0.81
Chemical-induced, nonlethal, developmental model of dissecting aortic aneurysm. Birth Defects Res A Clin Mol Teratol (2006) 0.81
A rare human sequence variant reveals myocardin autoinhibition. J Biol Chem (2008) 0.80
Spatiotemporal regulation of an Hcn4 enhancer defines a role for Mef2c and HDACs in cardiac electrical patterning. Dev Biol (2012) 0.80
Heart malformation: what are the chances it could happen again? Circulation (2009) 0.80
Nonlinear imaging study of extracellular matrix in chemical-induced, developmental dissecting aortic aneurysm: evidence for defective collagen type III. Birth Defects Res A Clin Mol Teratol (2008) 0.79
Monkeying around with cardiac progenitors: hope for the future. J Clin Invest (2010) 0.78