Identification, activation, and selective in vivo ablation of mouse NK cells via NKp46.

PubWeight™: 3.60‹?› | Rank: Top 1%

🔗 View Article (PMC 1805551)

Published in Proc Natl Acad Sci U S A on February 20, 2007

Authors

Thierry Walzer1, Mathieu Bléry, Julie Chaix, Nicolas Fuseri, Lionel Chasson, Scott H Robbins, Sébastien Jaeger, Pascale André, Laurent Gauthier, Laurent Daniel, Karine Chemin, Yannis Morel, Marc Dalod, Jean Imbert, Michel Pierres, Alessandro Moretta, François Romagné, Eric Vivier

Author Affiliations

1: Centre d'Immunologie de Marseille-Luminy, Université de la Méditerranée, 13288 Marseille, France. walzer@ciml.univ-mrs.fr

Articles citing this

(truncated to the top 100)

Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters. Nat Med (2009) 9.71

Innate or adaptive immunity? The example of natural killer cells. Science (2011) 8.68

Human natural killer cells. Blood (2008) 7.37

RORgammat and commensal microflora are required for the differentiation of mucosal interleukin 22-producing NKp46+ cells. Nat Immunol (2008) 5.91

Influence of the transcription factor RORgammat on the development of NKp46+ cell populations in gut and skin. Nat Immunol (2008) 4.78

The transcription factors T-bet and Eomes control key checkpoints of natural killer cell maturation. Immunity (2012) 4.32

The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells. Nature (2014) 3.45

The XC chemokine receptor 1 is a conserved selective marker of mammalian cells homologous to mouse CD8alpha+ dendritic cells. J Exp Med (2010) 3.20

IL-7 and IL-15 independently program the differentiation of intestinal CD3-NKp46+ cell subsets from Id2-dependent precursors. J Exp Med (2010) 2.87

Reprogramming of T cells to natural killer-like cells upon Bcl11b deletion. Science (2010) 2.77

Functionally distinct subsets of human NK cells and monocyte/DC-like cells identified by coexpression of CD56, CD7, and CD4. Blood (2009) 2.43

Liver-resident NK cells confer adaptive immunity in skin-contact inflammation. J Clin Invest (2013) 2.21

NK cell responsiveness is tuned commensurate with the number of inhibitory receptors for self-MHC class I: the rheostat model. J Immunol (2009) 2.12

Membrane-bound IL-21 promotes sustained ex vivo proliferation of human natural killer cells. PLoS One (2012) 2.09

Interleukin-22-producing innate immune cells: new players in mucosal immunity and tissue repair? Nat Rev Immunol (2009) 2.04

Fate mapping analysis of lymphoid cells expressing the NKp46 cell surface receptor. Proc Natl Acad Sci U S A (2011) 2.01

Regulation of hierarchical clustering and activation of innate immune cells by dendritic cells. Immunity (2008) 1.97

Tissue-resident natural killer (NK) cells are cell lineages distinct from thymic and conventional splenic NK cells. Elife (2014) 1.97

Oxysterols direct B-cell migration through EBI2. Nature (2011) 1.94

T-bet-dependent S1P5 expression in NK cells promotes egress from lymph nodes and bone marrow. J Exp Med (2009) 1.86

T-bet and Eomes instruct the development of two distinct natural killer cell lineages in the liver and in the bone marrow. J Exp Med (2014) 1.82

CD11cloB220+ interferon-producing killer dendritic cells are activated natural killer cells. J Exp Med (2007) 1.82

Activating receptors promote NK cell expansion for maintenance, IL-10 production, and CD8 T cell regulation during viral infection. J Exp Med (2009) 1.70

Posttranscriptional regulation of II10 gene expression allows natural killer cells to express immunoregulatory function. Immunity (2008) 1.65

NK cells impede glioblastoma virotherapy through NKp30 and NKp46 natural cytotoxicity receptors. Nat Med (2012) 1.52

Control of epithelial cell function by interleukin-22-producing RORγt+ innate lymphoid cells. Immunology (2011) 1.50

IL-12 initiates tumor rejection via lymphoid tissue-inducer cells bearing the natural cytotoxicity receptor NKp46. Nat Immunol (2010) 1.43

The p110 delta of PI3K plays a critical role in NK cell terminal maturation and cytokine/chemokine generation. J Exp Med (2008) 1.34

Interleukin-22 (IL-22) production by pulmonary Natural Killer cells and the potential role of IL-22 during primary influenza virus infection. J Virol (2010) 1.34

CD56negCD16⁺ NK cells are activated mature NK cells with impaired effector function during HIV-1 infection. Retrovirology (2013) 1.30

NKp46 identifies an NKT cell subset susceptible to leukemic transformation in mouse and human. J Clin Invest (2011) 1.30

Natural killer cells: integrating diversity with function. Immunology (2009) 1.25

Dendritic cell regulation of carbon tetrachloride-induced murine liver fibrosis regression. Hepatology (2012) 1.24

HLA-E expression by gynecological cancers restrains tumor-infiltrating CD8⁺ T lymphocytes. Proc Natl Acad Sci U S A (2011) 1.17

Ischemic neurons recruit natural killer cells that accelerate brain infarction. Proc Natl Acad Sci U S A (2014) 1.16

NK cells are effectors for resolvin E1 in the timely resolution of allergic airway inflammation. J Immunol (2011) 1.13

The histone deacetylase inhibitor valproic acid lessens NK cell action against oncolytic virus-infected glioblastoma cells by inhibition of STAT5/T-BET signaling and generation of gamma interferon. J Virol (2012) 1.13

Natural cytotoxicity receptors: broader expression patterns and functions in innate and adaptive immune cells. Front Immunol (2013) 1.13

Homeostatic control of conjunctival mucosal goblet cells by NKT-derived IL-13. Mucosal Immunol (2010) 1.13

NKG2D is critical for NK cell activation in host defense against Pseudomonas aeruginosa respiratory infection. J Immunol (2008) 1.12

Human natural killer cells prevent infectious mononucleosis features by targeting lytic Epstein-Barr virus infection. Cell Rep (2013) 1.12

Natural killer cells trigger osteoclastogenesis and bone destruction in arthritis. Proc Natl Acad Sci U S A (2010) 1.11

Cellular and molecular basis of haploidentical hematopoietic stem cell transplantation in the successful treatment of high-risk leukemias: role of alloreactive NK cells. Front Immunol (2013) 1.10

Mapping of NKp46(+) Cells in Healthy Human Lymphoid and Non-Lymphoid Tissues. Front Immunol (2012) 1.10

Regulatory NK-cell functions in inflammation and autoimmunity. Mol Med (2009) 1.09

TGF-β is responsible for NK cell immaturity during ontogeny and increased susceptibility to infection during mouse infancy. Nat Immunol (2012) 1.08

Role of innate lymphocytes in infection and inflammation. Front Immunol (2012) 1.08

NK cell self tolerance, responsiveness and missing self recognition. Semin Immunol (2014) 1.08

Cerebral malaria: mysteries at the blood-brain barrier. Virulence (2012) 1.05

Human liver-resident CD56(bright)/CD16(neg) NK cells are retained within hepatic sinusoids via the engagement of CCR5 and CXCR6 pathways. J Autoimmun (2015) 1.05

NK cells and cancer: you can teach innate cells new tricks. Nat Rev Cancer (2015) 1.04

Tissue-resident natural killer cells and their potential diversity. Semin Immunol (2014) 1.03

Salivary gland NK cells are phenotypically and functionally unique. PLoS Pathog (2011) 1.02

The role of natural killer cells in sepsis. J Biomed Biotechnol (2011) 1.02

NK cells promote Th-17 mediated corneal barrier disruption in dry eye. PLoS One (2012) 1.02

NK cells controlling virus-specific T cells: Rheostats for acute vs. persistent infections. Virology (2013) 1.01

The phylogenetic origins of natural killer receptors and recognition: relationships, possibilities, and realities. Immunogenetics (2010) 1.01

Human natural killer cell development in secondary lymphoid tissues. Semin Immunol (2014) 1.01

Natural killer and natural killer T cells in liver fibrosis. Biochim Biophys Acta (2012) 1.00

Coordinated regulation of NK receptor expression in the maturing human immune system. J Immunol (2014) 0.99

Infection-induced regulation of natural killer cells by macrophages and collagen at the lymph node subcapsular sinus. Cell Rep (2012) 0.98

Natural killer receptors: the burden of a name. J Exp Med (2010) 0.98

Human NK cells kill resting but not activated microglia via NKG2D- and NKp46-mediated recognition. J Immunol (2008) 0.98

Natural killer cells: role in local tumor growth and metastasis. Biologics (2012) 0.94

Utilizing cytokines to function-enable human NK cells for the immunotherapy of cancer. Scientifica (Cairo) (2014) 0.94

NKG2D mediates NK cell hyperresponsiveness and influenza-induced pathologies in a mouse model of chronic obstructive pulmonary disease. J Immunol (2012) 0.94

Natural killer cells in allogeneic transplantation: effect on engraftment, graft- versus-tumor, and graft-versus-host responses. Biol Blood Marrow Transplant (2009) 0.94

The transcription factor E4BP4 is not required for extramedullary pathways of NK cell development. J Immunol (2014) 0.93

NKp46 defines ovine cells that have characteristics corresponding to NK cells. Vet Res (2011) 0.93

Regulation of NK cell repertoire and function in the liver. Crit Rev Immunol (2011) 0.93

Mast cells expedite control of pulmonary murine cytomegalovirus infection by enhancing the recruitment of protective CD8 T cells to the lungs. PLoS Pathog (2014) 0.93

Murine endometrial and decidual NK1.1+ natural killer cells display a B220+CD11c+ cell surface phenotype. Biol Reprod (2009) 0.92

Multiple hats for natural killers. Curr Opin Immunol (2010) 0.92

Potential role of NK cells in the pathogenesis of inflammatory bowel disease. J Biomed Biotechnol (2011) 0.91

Interleukin (IL)-21-independent pathogen-specific CD8+ T-cell expansion, and IL-21-dependent suppression of CD4+ T-cell IL-17 production. Immunology (2010) 0.90

IL-10 restricts activation-induced death of NK cells during acute murine cytomegalovirus infection. J Immunol (2011) 0.90

Generation of a novel regulatory NK cell subset from peripheral blood CD34+ progenitors promoted by membrane-bound IL-15. PLoS One (2008) 0.90

Tissue-Resident NK Cells Mediate Ischemic Kidney Injury and Are Not Depleted by Anti-Asialo-GM1 Antibody. J Immunol (2015) 0.90

Role of runt-related transcription factor 3 (RUNX3) in transcription regulation of natural cytotoxicity receptor 1 (NCR1/NKp46), an activating natural killer (NK) cell receptor. J Biol Chem (2012) 0.88

Natural killer cells are recruited during pulmonary tuberculosis and their ex vivo responses to mycobacteria vary between healthy human donors in association with KIR haplotype. Cell Microbiol (2012) 0.88

Natural killer cells and their receptors in multiple sclerosis. Brain (2012) 0.87

Protection from inflammatory organ damage in a murine model of hemophagocytic lymphohistiocytosis using treatment with IL-18 binding protein. Front Immunol (2012) 0.87

Methamphetamine administration targets multiple immune subsets and induces phenotypic alterations suggestive of immunosuppression. PLoS One (2012) 0.87

Natural killer cells in immunodefense against infective agents. Expert Rev Anti Infect Ther (2008) 0.86

PDK1 orchestrates early NK cell development through induction of E4BP4 expression and maintenance of IL-15 responsiveness. J Exp Med (2015) 0.86

Interactions between the intestinal microbiota and innate lymphoid cells. Gut Microbes (2013) 0.86

Bovine neonate natural killer cells are fully functional and highly responsive to interleukin-15 and to NKp46 receptor stimulation. Vet Res (2009) 0.86

Lineage relationships of human interleukin-22-producing CD56+ RORγt+ innate lymphoid cells and conventional natural killer cells. Blood (2013) 0.85

Deciphering the Multifaceted Relationship between Oncolytic Viruses and Natural Killer Cells. Adv Virol (2011) 0.85

Interleukin-21 induces the differentiation of human umbilical cord blood CD34-lineage- cells into pseudomature lytic NK cells. BMC Immunol (2009) 0.85

Porcine CD8αdim/-NKp46high NK cells are in a highly activated state. Vet Res (2013) 0.84

The host environment is responsible for aging-related functional NK cell deficiency. J Immunol (2013) 0.83

Evasion of natural killer cells by influenza virus. J Leukoc Biol (2010) 0.83

Parasite-mediated upregulation of NK cell-derived gamma interferon protects against severe highly pathogenic H5N1 influenza virus infection. J Virol (2011) 0.82

Increased cytotoxicity of CD4+ invariant NKT cells against CD4+CD25hiCD127lo/- regulatory T cells in allergic asthma. Eur J Immunol (2008) 0.82

Natural killer cell NKG2D and granzyme B are critical for allergic pulmonary inflammation. J Allergy Clin Immunol (2013) 0.82

Lactobacillus gasseri OLL2809 inhibits development of ectopic endometrial cell in peritoneal cavity via activation of NK cells in a murine endometriosis model. Cytotechnology (2011) 0.81

NKp46+ CD3+ cells: a novel nonconventional T cell subset in cattle exhibiting both NK cell and T cell features. J Immunol (2014) 0.81

Innate immunity in multiple sclerosis white matter lesions: expression of natural cytotoxicity triggering receptor 1 (NCR1). J Neuroinflammation (2012) 0.80

NK cell development in bone marrow and liver: site matters. Genes Immun (2014) 0.80

Articles cited by this

In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens. Immunity (2002) 14.57

Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis. Annu Rev Immunol (2001) 7.07

Dynamics and function of Langerhans cells in vivo: dermal dendritic cells colonize lymph node areas distinct from slower migrating Langerhans cells. Immunity (2005) 6.48

Lethal influenza infection in the absence of the natural killer cell receptor gene Ncr1. Nat Immunol (2006) 5.00

Type 2 immunity reflects orchestrated recruitment of cells committed to IL-4 production. Immunity (2004) 4.81

Recognition of haemagglutinins on virus-infected cells by NKp46 activates lysis by human NK cells. Nature (2001) 4.76

Natural killer cells and pregnancy. Nat Rev Immunol (2002) 4.21

Synergy among receptors on resting NK cells for the activation of natural cytotoxicity and cytokine secretion. Blood (2005) 3.99

Ex vivo identification, isolation and analysis of tumor-cytolytic T cells. Nat Med (2003) 3.60

New aspects of natural-killer-cell surveillance and therapy of cancer. Nat Rev Cancer (2002) 3.38

Natural killer cell developmental pathways: a question of balance. Annu Rev Immunol (2006) 3.31

Activated primary and memory CD8 T cells migrate to nonlymphoid tissues regardless of site of activation or tissue of origin. J Immunol (2004) 3.15

Natural-killer cells and dendritic cells: "l'union fait la force". Blood (2005) 3.10

Molecular cloning of NKp46: a novel member of the immunoglobulin superfamily involved in triggering of natural cytotoxicity. J Exp Med (1998) 3.09

Unravelling natural killer cell function: triggering and inhibitory human NK receptors. EMBO J (2003) 3.06

Close encounters of different kinds: dendritic cells and NK cells take centre stage. Nat Rev Immunol (2005) 2.77

In vivo natural killer cell activities revealed by natural killer cell-deficient mice. Proc Natl Acad Sci U S A (2000) 2.76

p46, a novel natural killer cell-specific surface molecule that mediates cell activation. J Exp Med (1997) 2.70

Natural killer cell behavior in lymph nodes revealed by static and real-time imaging. J Exp Med (2006) 2.30

Development of human lymphoid cells. Annu Rev Immunol (2006) 2.22

Identity of Leu-19 (CD56) leukocyte differentiation antigen and neural cell adhesion molecule. J Exp Med (1989) 2.17

NK markers are expressed on a high percentage of virus-specific CD8+ and CD4+ T cells. J Immunol (2000) 2.15

Interplay of natural killer cells and their receptors with the adaptive immune response. Nat Immunol (2004) 2.14

What is a natural killer cell? Nat Immunol (2002) 2.11

Cutting edge: the mouse NK cell-associated antigen recognized by DX5 monoclonal antibody is CD49b (alpha 2 integrin, very late antigen-2). J Immunol (2001) 2.09

Turnover and proliferation of NK cells in steady state and lymphopenic conditions. J Immunol (2004) 2.07

Reprogramming of CTLs into natural killer-like cells in celiac disease. J Exp Med (2006) 2.03

Natural killer cells distinguish innocuous and destructive forms of pancreatic islet autoimmunity. Proc Natl Acad Sci U S A (2004) 1.96

Natural cytotoxicity receptors that trigger human NK-cell-mediated cytolysis. Immunol Today (2000) 1.95

TRAIL identifies immature natural killer cells in newborn mice and adult mouse liver. Blood (2004) 1.83

Inhibitory NK-cell receptors on T cells: witness of the past, actors of the future. Nat Rev Immunol (2004) 1.68

Association with FcRgamma is essential for activation signal through NKR-P1 (CD161) in natural killer (NK) cells and NK1.1+ T cells. J Exp Med (1997) 1.66

Natural killer cell and macrophage cooperation in MyD88-dependent innate responses to Plasmodium falciparum. Proc Natl Acad Sci U S A (2005) 1.50

NKp46 defines a subset of bovine leukocytes with natural killer cell characteristics. Eur J Immunol (2004) 1.48

Early expression of triggering receptors and regulatory role of 2B4 in human natural killer cell precursors undergoing in vitro differentiation. Proc Natl Acad Sci U S A (2002) 1.40

NKR-P1, an activating molecule on rat natural killer cells, stimulates phosphoinositide turnover and a rise in intracellular calcium. J Immunol (1991) 1.31

Distinguishing features of developing natural killer cells. Curr Opin Immunol (2005) 1.31

Molecular and genetic basis for strain-dependent NK1.1 alloreactivity of mouse NK cells. J Immunol (2006) 1.28

Natural killer T cells reactive to a single glycolipid exhibit a highly diverse T cell receptor beta repertoire and small clone size. Proc Natl Acad Sci U S A (2001) 1.22

Analysis of in situ NK cell responses during viral infection. J Immunol (2001) 1.22

NK cells: elusive players in autoimmunity. Trends Immunol (2005) 1.17

Differential regulation of killer cell lectin-like receptor G1 expression on T cells. J Immunol (2003) 1.13

NKp30 (NCR3) is a pseudogene in 12 inbred and wild mouse strains, but an expressed gene in Mus caroli. Mol Biol Evol (2005) 1.12

Rat NKp46 activates natural killer cell cytotoxicity and is associated with FcepsilonRIgamma and CD3zeta. J Leukoc Biol (2004) 1.10

NK1.1+ cells and murine cytomegalovirus infection: what happens in situ? J Immunol (2001) 1.05

Development and functional analysis of eosinophils from murine embryonic stem cells. Br J Haematol (2004) 1.03

Arrested natural killer cell development associated with transgene insertion into the Atf2 locus. Blood (2005) 0.99

Strategies of natural killer cell recognition and signaling. Curr Top Microbiol Immunol (2006) 0.96

Natural killer cell alloreactivity in haploidentical hematopoietic stem cell transplantation. Int J Hematol (2005) 0.82

Articles by these authors

Innate or adaptive immunity? The example of natural killer cells. Science (2011) 8.68

Innate lymphoid cells--a proposal for uniform nomenclature. Nat Rev Immunol (2013) 7.94

Human NK cell education by inhibitory receptors for MHC class I. Immunity (2006) 6.73

Nomenclature of monocytes and dendritic cells in blood. Blood (2010) 6.63

TLR3 deficiency in patients with herpes simplex encephalitis. Science (2007) 5.86

Influence of the transcription factor RORgammat on the development of NKp46+ cell populations in gut and skin. Nat Immunol (2008) 4.78

The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide. Science (2013) 4.60

The transcription factors T-bet and Eomes control key checkpoints of natural killer cell maturation. Immunity (2012) 4.32

Novel insights into the relationships between dendritic cell subsets in human and mouse revealed by genome-wide expression profiling. Genome Biol (2008) 3.93

Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule. J Exp Med (2003) 3.52

Ex vivo analysis of human memory CD4 T cells specific for hepatitis C virus using MHC class II tetramers. J Clin Invest (2003) 3.40

Maturation of mouse NK cells is a 4-stage developmental program. Blood (2009) 3.31

A novel dendritic cell subset involved in tumor immunosurveillance. Nat Med (2006) 3.21

The XC chemokine receptor 1 is a conserved selective marker of mammalian cells homologous to mouse CD8alpha+ dendritic cells. J Exp Med (2010) 3.20

The B7 family member B7-H6 is a tumor cell ligand for the activating natural killer cell receptor NKp30 in humans. J Exp Med (2009) 3.17

Natural-killer cells and dendritic cells: "l'union fait la force". Blood (2005) 3.10

Unravelling natural killer cell function: triggering and inhibitory human NK receptors. EMBO J (2003) 3.06

Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors. Nat Med (2011) 3.03

Major histocompatibility complex class I-related chain A and UL16-binding protein expression on tumor cell lines of different histotypes: analysis of tumor susceptibility to NKG2D-dependent natural killer cell cytotoxicity. Cancer Res (2002) 3.00

CD56brightCD16- killer Ig-like receptor- NK cells display longer telomeres and acquire features of CD56dim NK cells upon activation. J Immunol (2007) 2.97

CD4+CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor-beta-dependent manner. J Exp Med (2005) 2.93

Selective associations with signaling proteins determine stimulatory versus costimulatory activity of NKG2D. Nat Immunol (2002) 2.87

Selective predisposition to bacterial infections in IRAK-4-deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunity. J Exp Med (2007) 2.85

Characterization of CD56-/CD16+ natural killer (NK) cells: a highly dysfunctional NK subset expanded in HIV-infected viremic individuals. Proc Natl Acad Sci U S A (2005) 2.80

Preclinical characterization of 1-7F9, a novel human anti-KIR receptor therapeutic antibody that augments natural killer-mediated killing of tumor cells. Blood (2009) 2.75

Both integrated and differential regulation of components of the IL-2/IL-2 receptor system. Cytokine Growth Factor Rev (2006) 2.71

Transforming growth factor beta 1 inhibits expression of NKp30 and NKG2D receptors: consequences for the NK-mediated killing of dendritic cells. Proc Natl Acad Sci U S A (2003) 2.71

The abundant NK cells in human secondary lymphoid tissues require activation to express killer cell Ig-like receptors and become cytolytic. J Immunol (2004) 2.64

The trafficking of natural killer cells. Immunol Rev (2007) 2.62

Prevalence and seasonal variations of six bee viruses in Apis mellifera L. and Varroa destructor mite populations in France. Appl Environ Microbiol (2004) 2.56

Recognition of peptide-MHC class I complexes by activating killer immunoglobulin-like receptors. Proc Natl Acad Sci U S A (2005) 2.55

Type I interferon dependence of plasmacytoid dendritic cell activation and migration. J Exp Med (2005) 2.53

Natural killer cells in HIV-1 infection: dichotomous effects of viremia on inhibitory and activating receptors and their functional correlates. Proc Natl Acad Sci U S A (2003) 2.51

Human breast cancer cells enhance self tolerance by promoting evasion from NK cell antitumor immunity. J Clin Invest (2011) 2.44

H3K4 tri-methylation provides an epigenetic signature of active enhancers. EMBO J (2011) 2.38

NK-dependent DC maturation is mediated by TNFalpha and IFNgamma released upon engagement of the NKp30 triggering receptor. Blood (2005) 2.31

The impaired NK cell cytolytic function in viremic HIV-1 infection is associated with a reduced surface expression of natural cytotoxicity receptors (NKp46, NKp30 and NKp44). Eur J Immunol (2003) 2.29

Human inflammatory dendritic cells induce Th17 cell differentiation. Immunity (2013) 2.23

CpG and double-stranded RNA trigger human NK cells by Toll-like receptors: induction of cytokine release and cytotoxicity against tumors and dendritic cells. Proc Natl Acad Sci U S A (2004) 2.23

Defective expression and function of natural killer cell-triggering receptors in patients with acute myeloid leukemia. Blood (2002) 2.21

Origins and functional specialization of macrophages and of conventional and monocyte-derived dendritic cells in mouse skin. Immunity (2013) 2.20

Analysis of the receptor-ligand interactions in the natural killer-mediated lysis of freshly isolated myeloid or lymphoblastic leukemias: evidence for the involvement of the Poliovirus receptor (CD155) and Nectin-2 (CD112). Blood (2004) 2.17

Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment. J Exp Med (2008) 2.17

NK cell responsiveness is tuned commensurate with the number of inhibitory receptors for self-MHC class I: the rheostat model. J Immunol (2009) 2.12

Germ-line and rearranged Tcrd transcription distinguish bona fide NK cells and NK-like gammadelta T cells. Eur J Immunol (2007) 2.11

Skin-draining lymph nodes contain dermis-derived CD103(-) dendritic cells that constitutively produce retinoic acid and induce Foxp3(+) regulatory T cells. Blood (2010) 2.09

Cutting edge: Priming of NK cells by IL-18. J Immunol (2008) 2.08

Immunoreceptor tyrosine-based inhibition motifs: a quest in the past and future. Immunol Rev (2008) 2.05

Fate mapping analysis of lymphoid cells expressing the NKp46 cell surface receptor. Proc Natl Acad Sci U S A (2011) 2.01

Natural killer cell trafficking in vivo requires a dedicated sphingosine 1-phosphate receptor. Nat Immunol (2007) 2.00

The role of chemerin in the colocalization of NK and dendritic cell subsets into inflamed tissues. Blood (2007) 1.99

Tuning of natural killer cell reactivity by NKp46 and Helios calibrates T cell responses. Science (2012) 1.98

Cutting edge: CD8+ T cell priming in the absence of NK cells leads to enhanced memory responses. J Immunol (2011) 1.97

Anti-leukemia activity of alloreactive NK cells in KIR ligand-mismatched haploidentical HSCT for pediatric patients: evaluation of the functional role of activating KIR and redefinition of inhibitory KIR specificity. Blood (2008) 1.96

DNAM-1 and PVR regulate monocyte migration through endothelial junctions. J Exp Med (2004) 1.96

Identification of 4Ig-B7-H3 as a neuroblastoma-associated molecule that exerts a protective role from an NK cell-mediated lysis. Proc Natl Acad Sci U S A (2004) 1.95

Natural killer cells promote early CD8 T cell responses against cytomegalovirus. PLoS Pathog (2007) 1.93

MyD88-dependent and -independent murine cytomegalovirus sensing for IFN-alpha release and initiation of immune responses in vivo. J Immunol (2005) 1.92

Surface NK receptors and their ligands on tumor cells. Semin Immunol (2006) 1.92

Profound coordinated alterations of intratumoral NK cell phenotype and function in lung carcinoma. Cancer Res (2011) 1.91

Natural killer cell-mediated killing of freshly isolated neuroblastoma cells: critical role of DNAX accessory molecule-1-poliovirus receptor interaction. Cancer Res (2004) 1.87

Cellular ligands of activating NK receptors. Trends Immunol (2005) 1.84

Killer immunoglobulin-like receptors. Curr Opin Immunol (2004) 1.83

The three-dimensional structure of the human NK cell receptor NKp44, a triggering partner in natural cytotoxicity. Structure (2003) 1.82

Phenotypic and functional heterogeneity of human NK cells developing after umbilical cord blood transplantation: a role for human cytomegalovirus? Blood (2011) 1.78

NKp46 and NKG2D recognition of infected dendritic cells is necessary for NK cell activation in the human response to influenza infection. J Immunol (2007) 1.78

Nucleic acid agonists for Toll-like receptor 7 are defined by the presence of uridine ribonucleotides. Eur J Immunol (2006) 1.76

Impaired Epstein-Barr virus-specific CD8+ T-cell function in X-linked lymphoproliferative disease is restricted to SLAM family-positive B-cell targets. Blood (2010) 1.75

Identity, regulation and in vivo function of gut NKp46+RORγt+ and NKp46+RORγt- lymphoid cells. EMBO J (2011) 1.74

Jinx, an MCMV susceptibility phenotype caused by disruption of Unc13d: a mouse model of type 3 familial hemophagocytic lymphohistiocytosis. J Exp Med (2007) 1.73

The speed of change: towards a discontinuity theory of immunity? Nat Rev Immunol (2013) 1.72