Published in J Exp Med on March 26, 2007
Evolutionary struggles between NK cells and viruses. Nat Rev Immunol (2008) 3.79
Controlling natural killer cell responses: integration of signals for activation and inhibition. Annu Rev Immunol (2013) 3.38
Posttranscriptional regulation of II10 gene expression allows natural killer cells to express immunoregulatory function. Immunity (2008) 1.65
Key role of splenic myeloid DCs in the IFN-alphabeta response to adenoviruses in vivo. PLoS Pathog (2008) 1.58
Cytoskeletal stabilization of inhibitory interactions in immunologic synapses of mature human dendritic cells with natural killer cells. Blood (2011) 1.56
iNOS-producing inflammatory dendritic cells constitute the major infected cell type during the chronic Leishmania major infection phase of C57BL/6 resistant mice. PLoS Pathog (2009) 1.53
Modulation of dendritic cell function by Leishmania parasites. J Immunol (2008) 1.40
Toll-like receptors and leishmaniasis. Infect Immun (2007) 1.27
Distinct roles for MyD88 and Toll-like receptor 2 during Leishmania braziliensis infection in mice. Infect Immun (2009) 1.24
Down-regulation of dendritic cell signaling pathways by Leishmania amazonensis amastigotes. Mol Immunol (2008) 1.20
Genetic and antibody-mediated reprogramming of natural killer cell missing-self recognition in vivo. Proc Natl Acad Sci U S A (2009) 1.16
IL-17 mediates immunopathology in the absence of IL-10 following Leishmania major infection. PLoS Pathog (2013) 1.15
The early interaction of Leishmania with macrophages and dendritic cells and its influence on the host immune response. Front Cell Infect Microbiol (2012) 1.08
Type I IFN receptor regulates neutrophil functions and innate immunity to Leishmania parasites. J Immunol (2010) 1.06
The role of leishmania proteophosphoglycans in sand fly transmission and infection of the Mammalian host. Front Microbiol (2012) 1.03
Toll-like receptors in leishmania infections: guardians or promoters? J Parasitol Res (2012) 1.03
Modulation of dendritic cell responses by parasites: a common strategy to survive. J Biomed Biotechnol (2010) 1.02
Leishmania interferes with host cell signaling to devise a survival strategy. J Biomed Biotechnol (2010) 1.01
Mechanisms of resistance and susceptibility to experimental visceral leishmaniosis: BALB/c mouse versus Syrian hamster model. Vet Res (2011) 1.00
Lymph node hypertrophy following Leishmania major infection is dependent on TLR9. J Immunol (2011) 1.00
IL-10-producing Th1 cells and disease progression are regulated by distinct CD11c⁺ cell populations during visceral leishmaniasis. PLoS Pathog (2012) 1.00
Infection-induced regulation of natural killer cells by macrophages and collagen at the lymph node subcapsular sinus. Cell Rep (2012) 0.98
Innate killing of Leishmania donovani by macrophages of the splenic marginal zone requires IRF-7. PLoS Pathog (2010) 0.98
Role of Toll-like receptor 9 signaling in experimental Leishmania braziliensis infection. Infect Immun (2013) 0.97
Critical role of IRF-5 in the development of T helper 1 responses to Leishmania donovani infection. PLoS Pathog (2011) 0.96
Activation of natural killer cells during microbial infections. Front Immunol (2012) 0.96
Role of natural killer cells in modulating dendritic cell responses to Leishmania amazonensis infection. Infect Immun (2008) 0.95
Deception and manipulation: the arms of leishmania, a successful parasite. Front Immunol (2014) 0.93
Leishmania expressed lipophosphoglycan interacts with Toll-like receptor (TLR)-2 to decrease TLR-9 expression and reduce anti-leishmanial responses. Clin Exp Immunol (2013) 0.93
Rickettsiae stimulate dendritic cells through toll-like receptor 4, leading to enhanced NK cell activation in vivo. J Infect Dis (2009) 0.93
Leishmania pifanoi proteoglycolipid complex P8 induces macrophage cytokine production through Toll-like receptor 4. Infect Immun (2008) 0.92
Toll-like receptors participate in macrophage activation and intracellular control of Leishmania (Viannia) panamensis. Infect Immun (2011) 0.91
Infection with Vpr-positive human immunodeficiency virus type 1 impairs NK cell function indirectly through cytokine dysregulation of infected target cells. J Virol (2008) 0.91
Activation of phosphatidylinositol 3-kinase/Akt and impairment of nuclear factor-kappaB: molecular mechanisms behind the arrested maturation/activation state of Leishmania infantum-infected dendritic cells. Am J Pathol (2010) 0.90
TLR4 and NKT cell synergy in immunotherapy against visceral leishmaniasis. PLoS Pathog (2012) 0.87
Leishmania donovani-induced expression of signal regulatory protein alpha on Kupffer cells enhances hepatic invariant NKT-cell activation. Eur J Immunol (2010) 0.86
Natural killer cells in immunodefense against infective agents. Expert Rev Anti Infect Ther (2008) 0.86
Lessons from other diseases: granulomatous inflammation in leishmaniasis. Semin Immunopathol (2015) 0.85
Dendritic cells are required for optimal activation of natural killer functions following primary infection with herpes simplex virus type 1. J Virol (2009) 0.85
IL-18, but not IL-15, contributes to the IL-12-dependent induction of NK-cell effector functions by Leishmania infantum in vivo. Eur J Immunol (2010) 0.85
Glycoinositolphospholipids from Leishmania braziliensis and L. infantum: modulation of innate immune system and variations in carbohydrate structure. PLoS Negl Trop Dis (2012) 0.85
Immunoregulatory profile of monocytes from cutaneous leishmaniasis patients and association with lesion size. Parasite Immunol (2013) 0.84
Expression of Toll-like receptors 2 and 9 in cells of dog jejunum and colon naturally infected with Leishmania infantum. BMC Immunol (2013) 0.84
Leishmania-infected macrophages are targets of NK cell-derived cytokines but not of NK cell cytotoxicity. Infect Immun (2011) 0.84
Characteristics of "Tip-DCs and MDSCs" and Their Potential Role in Leishmaniasis. Front Microbiol (2012) 0.83
NK cell activity differs between patients with localized and diffuse cutaneous leishmaniasis infected with Leishmania mexicana: a comparative study of TLRs and cytokines. PLoS One (2014) 0.82
Natural killer cells in experimental and human leishmaniasis. Front Cell Infect Microbiol (2012) 0.82
Dendritic cells and parasites: from recognition and activation to immune response instruction. Semin Immunopathol (2016) 0.82
TLR9 and MyD88 are crucial for the maturation and activation of dendritic cells by paromomycin-miltefosine combination therapy in visceral leishmaniasis. Br J Pharmacol (2014) 0.82
Innate immunity against Leishmania infections. Cell Microbiol (2015) 0.81
The quantitative and functional changes of NK cells in mice infected with Angiostrongylus cantonensis. Parasitol Res (2014) 0.79
TLR9 activation is triggered by the excess of stimulatory versus inhibitory motifs present in Trypanosomatidae DNA. PLoS Negl Trop Dis (2014) 0.79
NK Cell Proliferation Induced by IL-15 Transpresentation Is Negatively Regulated by Inhibitory Receptors. J Immunol (2015) 0.78
Possibilities and challenges for developing a successful vaccine for leishmaniasis. Parasit Vectors (2016) 0.78
Toll-Like Receptor 9 Signaling in Dendritic Cells Regulates Neutrophil Recruitment to Inflammatory Foci following Leishmania infantum Infection. Infect Immun (2015) 0.78
Functions of Murine Dendritic Cells. Immunity (2016) 0.77
Natural killer cells support the induction of protective immunity during dendritic cell-mediated vaccination against Leishmania major. Immunology (2010) 0.77
Antileishmanial effect of 18β-glycyrrhetinic acid is mediated by Toll-like receptor-dependent canonical and noncanonical p38 activation. Antimicrob Agents Chemother (2015) 0.76
Dendritic Cells and Leishmania Infection: Adding Layers of Complexity to a Complex Disease. J Immunol Res (2016) 0.76
Leishmania major Infection-Induced VEGF-A/VEGFR-2 Signaling Promotes Lymphangiogenesis That Controls Disease. J Immunol (2016) 0.75
Cathepsin B-Deficient Mice Resolve Leishmania major Inflammation Faster in a T Cell-Dependent Manner. PLoS Negl Trop Dis (2016) 0.75
Immune responses against protozoan parasites: a focus on the emerging role of Nod-like receptors. Cell Mol Life Sci (2016) 0.75
Pathogen recognition and innate immunity. Cell (2006) 44.14
A Toll-like receptor recognizes bacterial DNA. Nature (2000) 26.34
Neutrophil extracellular traps kill bacteria. Science (2004) 23.64
Functional role of type I and type II interferons in antiviral defense. Science (1994) 18.92
Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function. Immunity (1998) 18.12
An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow. J Immunol Methods (1999) 17.06
Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science (2004) 16.26
Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8. Science (2004) 14.80
In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens. Immunity (2002) 14.57
Plasmacytoid dendritic cells in immunity. Nat Immunol (2004) 9.11
Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides. J Immunol (2002) 7.60
The immunology of susceptibility and resistance to Leishmania major in mice. Nat Rev Immunol (2002) 6.59
Induced recruitment of NK cells to lymph nodes provides IFN-gamma for T(H)1 priming. Nat Immunol (2004) 5.80
Dendritic cells directly trigger NK cell functions: cross-talk relevant in innate anti-tumor immune responses in vivo. Nat Med (1999) 4.92
TLR9-dependent recognition of MCMV by IPC and DC generates coordinated cytokine responses that activate antiviral NK cell function. Immunity (2004) 4.50
Natural killer cells are a source of interferon gamma that drives differentiation of CD4+ T cell subsets and induces early resistance to Leishmania major in mice. J Exp Med (1993) 4.49
The development of murine plasmacytoid dendritic cell precursors is differentially regulated by FLT3-ligand and granulocyte/macrophage colony-stimulating factor. J Exp Med (2002) 3.91
Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin. J Exp Med (2005) 3.85
Natural killer cells and dendritic cells: rendezvous in abused tissues. Nat Rev Immunol (2002) 3.45
TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis. J Exp Med (2005) 3.44
Coordinated and distinct roles for IFN-alpha beta, IL-12, and IL-15 regulation of NK cell responses to viral infection. J Immunol (2002) 3.30
Functional interactions between dendritic cells and NK cells during viral infection. Nat Immunol (2002) 3.20
Histological analysis of CD11c-DTR/GFP mice after in vivo depletion of dendritic cells. Clin Exp Immunol (2005) 3.12
Transforming growth factor-beta controls T helper type 1 cell development through regulation of natural killer cell interferon-gamma. Nat Immunol (2005) 2.96
Toll-like receptor 9 binds single-stranded CpG-DNA in a sequence- and pH-dependent manner. Eur J Immunol (2004) 2.80
Close encounters of different kinds: dendritic cells and NK cells take centre stage. Nat Rev Immunol (2005) 2.77
Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response. Eur J Immunol (1996) 2.76
IL-12 is required for natural killer cell activation and subsequent T helper 1 cell development in experimental leishmaniasis. J Immunol (1995) 2.72
Natural killer cells and viral infections. Curr Opin Immunol (2003) 2.63
Type I interferon dependence of plasmacytoid dendritic cell activation and migration. J Exp Med (2005) 2.53
Control of coronavirus infection through plasmacytoid dendritic-cell-derived type I interferon. Blood (2006) 2.53
Virus-induced interferon alpha production by a dendritic cell subset in the absence of feedback signaling in vivo. J Exp Med (2002) 2.47
Reactivation of latent leishmaniasis by inhibition of inducible nitric oxide synthase. J Exp Med (1996) 2.45
The reciprocal interaction of NK cells with plasmacytoid or myeloid dendritic cells profoundly affects innate resistance functions. J Immunol (2005) 2.43
Malaria blood stage parasites activate human plasmacytoid dendritic cells and murine dendritic cells through a Toll-like receptor 9-dependent pathway. J Immunol (2004) 2.33
Natural killer cell behavior in lymph nodes revealed by static and real-time imaging. J Exp Med (2006) 2.30
CpG and double-stranded RNA trigger human NK cells by Toll-like receptors: induction of cytokine release and cytotoxicity against tumors and dendritic cells. Proc Natl Acad Sci U S A (2004) 2.23
Type 1 interferon (IFNalpha/beta) and type 2 nitric oxide synthase regulate the innate immune response to a protozoan parasite. Immunity (1998) 2.22
The immunobiology of the TLR9 subfamily. Trends Immunol (2004) 2.11
Leishmania lipophosphoglycan (LPG) activates NK cells through toll-like receptor-2. Mol Biochem Parasitol (2003) 2.08
Endosomal translocation of vertebrate DNA activates dendritic cells via TLR9-dependent and -independent pathways. J Immunol (2005) 2.02
Interferon-beta is required for interferon-alpha production in mouse fibroblasts. Curr Biol (1998) 1.95
Siglec-H is an IPC-specific receptor that modulates type I IFN secretion through DAP12. Blood (2005) 1.94
MyD88-dependent and -independent murine cytomegalovirus sensing for IFN-alpha release and initiation of immune responses in vivo. J Immunol (2005) 1.92
Dendritic cells, but not macrophages, produce IL-12 immediately following Leishmania donovani infection. Eur J Immunol (1998) 1.89
TLR9 is required for the gut-associated lymphoid tissue response following oral infection of Toxoplasma gondii. J Immunol (2006) 1.80
Interleukin 12 is effective treatment for an established systemic intracellular infection: experimental visceral leishmaniasis. J Exp Med (1995) 1.74
Neutralization of IL-12 demonstrates the existence of discrete organ-specific phases in the control of Leishmania donovani. Eur J Immunol (1998) 1.65
Visceral leishmaniasis in a German child who had never entered a known endemic area: case report and review of the literature. Clin Infect Dis (2000) 1.63
Early parasite containment is decisive for resistance to Leishmania major infection. Eur J Immunol (1995) 1.55
In vivo ablation of CD11c-positive dendritic cells increases susceptibility to herpes simplex virus type 1 infection and diminishes NK and T-cell responses. J Virol (2006) 1.53
Minute numbers of contaminant CD8+ T cells or CD11b+CD11c+ NK cells are the source of IFN-gamma in IL-12/IL-18-stimulated mouse macrophage populations. Blood (2004) 1.44
Suppressive effect of cyclosporin A on the development of Leishmania tropica-induced lesions in genetically susceptible BALB/c mice. J Immunol (1986) 1.43
Activation of human NK cells by plasmacytoid dendritic cells and its modulation by CD4+ T helper cells and CD4+ CD25hi T regulatory cells. Eur J Immunol (2005) 1.42
Role of NK cell-activating receptors and their ligands in the lysis of mononuclear phagocytes infected with an intracellular bacterium. J Immunol (2005) 1.39
Leishmaniasis in beige mice. Infect Immun (1982) 1.36
Leishmania major-infected murine langerhans cell-like dendritic cells from susceptible mice release IL-12 after infection and vaccinate against experimental cutaneous Leishmaniasis. Eur J Immunol (2000) 1.36
Natural killer cells participate in the early defense against Leishmania major infection in mice. Eur J Immunol (1993) 1.34
The induction of a type 1 immune response following a Trypanosoma brucei infection is MyD88 dependent. J Immunol (2005) 1.23
Two waves of antigen-containing dendritic cells in vivo in experimental Leishmania major infection. Eur J Immunol (2004) 1.20
Endogenous interleukin-12 regulates acquired resistance in experimental visceral leishmaniasis. J Infect Dis (1997) 1.18
IL-12 gene-deficient C57BL/6 mice are susceptible to Leishmania donovani but have diminished hepatic immunopathology. Eur J Immunol (2000) 1.17
Murine dendritic cells internalize Leishmania major promastigotes, produce IL-12 p40 and stimulate primary T cell proliferation in vitro. Eur J Immunol (1999) 1.17
Natural killer cells and innate immunity to protozoan pathogens. Int J Parasitol (2004) 1.15
Dendritic cell (DC)-based protection against an intracellular pathogen is dependent upon DC-derived IL-12 and can be induced by molecularly defined antigens. J Immunol (2003) 1.14
Protection against progressive leishmaniasis by IFN-beta. J Immunol (2004) 1.12
Specific recognition of virus-infected cells by paired NK receptors. Rev Med Virol (2004) 1.12
Bubonic leishmaniasis: a common manifestation of Leishmania (Viannia) braziliensis infection in Ceara, Brazil. Am J Trop Med Hyg (1995) 1.10
The outcome of the parasitic process initiated by Leishmania infantum in laboratory mice: a tissue-dependent pattern controlled by the Lsh and MHC loci. J Immunol (1996) 1.09
Participation of natural killer cells in the recovery of mice from visceral leishmaniasis. Cell Immunol (1985) 1.04
Dendritic cell populations in Leishmania major-infected skin and draining lymph nodes. Infect Immun (2004) 1.02
Hierarchy of susceptibility of dendritic cell subsets to infection by Leishmania major: inverse relationship to interleukin-12 production. Infect Immun (2002) 1.02
Isolation of kinetoplast DNA. Methods Mol Biol (1999) 0.89
Interleukin-2-activated natural killer cells may have a direct role in the control of Leishmania (Leishmania) amazonensis promastigote and macrophage infection. Scand J Immunol (2005) 0.86
Recognition of infected cells by natural killer cells. Curr Opin Immunol (2004) 0.86
Control of Leishmania major in the absence of Tyk2 kinase. Eur J Immunol (2004) 0.82
Impairment of natural killer cell activity in Indian kala-azar: restoration of activity by interleukin 2 but not by alpha or gamma interferon. Infect Immun (1993) 0.80
IL-22 increases the innate immunity of tissues. Immunity (2004) 8.30
IFNalpha activates dormant haematopoietic stem cells in vivo. Nature (2009) 7.17
Senescence surveillance of pre-malignant hepatocytes limits liver cancer development. Nature (2011) 6.14
IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis. Eur J Immunol (2006) 4.88
TLR9-dependent recognition of MCMV by IPC and DC generates coordinated cytokine responses that activate antiviral NK cell function. Immunity (2004) 4.50
Toll-like receptor-induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens. Nat Immunol (2008) 4.31
Type I interferon is selectively required by dendritic cells for immune rejection of tumors. J Exp Med (2011) 3.85
Distinct and nonredundant in vivo functions of IFNAR on myeloid cells limit autoimmunity in the central nervous system. Immunity (2008) 3.67
Cutting edge: immune cells as sources and targets of the IL-10 family members? J Immunol (2002) 3.63
The DNA sugar backbone 2' deoxyribose determines toll-like receptor 9 activation. Immunity (2008) 3.50
5'-Triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma. Nat Med (2008) 3.13
Postnatal acquisition of endotoxin tolerance in intestinal epithelial cells. J Exp Med (2006) 3.12
Toward biosimilar monoclonal antibodies. Nat Biotechnol (2008) 3.09
Functional anatomy of T cell activation and synapse formation. Annu Rev Immunol (2010) 3.01
Interferon-regulatory-factor 1 controls Toll-like receptor 9-mediated IFN-beta production in myeloid dendritic cells. Eur J Immunol (2007) 2.62
Virus-induced interferon alpha production by a dendritic cell subset in the absence of feedback signaling in vivo. J Exp Med (2002) 2.47
Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock. Nat Immunol (2003) 2.44
Cutting edge: enhancement of antibody responses through direct stimulation of B and T cells by type I IFN. J Immunol (2006) 2.38
Repetitive injections of dendritic cells matured with tumor necrosis factor alpha induce antigen-specific protection of mice from autoimmunity. J Exp Med (2002) 2.37
TRADD protein is an essential component of the RIG-like helicase antiviral pathway. Immunity (2008) 2.37
Myeloid type I interferon signaling promotes atherosclerosis by stimulating macrophage recruitment to lesions. Cell Metab (2010) 2.33
Priming of natural killer cells by nonmucosal mononuclear phagocytes requires instructive signals from commensal microbiota. Immunity (2012) 2.23
Direct stimulation of T cells by type I IFN enhances the CD8+ T cell response during cross-priming. J Immunol (2006) 2.20
Adjuvanticity of a synthetic cord factor analogue for subunit Mycobacterium tuberculosis vaccination requires FcRgamma-Syk-Card9-dependent innate immune activation. J Exp Med (2009) 2.03
Phenotypic and biochemical analyses of BACE1- and BACE2-deficient mice. J Biol Chem (2005) 2.03
Endosomal translocation of vertebrate DNA activates dendritic cells via TLR9-dependent and -independent pathways. J Immunol (2005) 2.02
Neutrophils responsive to endogenous IFN-beta regulate tumor angiogenesis and growth in a mouse tumor model. J Clin Invest (2010) 1.96
Cytosolic RIG-I-like helicases act as negative regulators of sterile inflammation in the CNS. Nat Neurosci (2011) 1.96
Targeted disruption of LIGHT causes defects in costimulatory T cell activation and reveals cooperation with lymphotoxin beta in mesenteric lymph node genesis. J Exp Med (2002) 1.95
CD8 T cells specific for lymphocytic choriomeningitis virus require type I IFN receptor for clonal expansion. J Immunol (2006) 1.92
La Crosse bunyavirus nonstructural protein NSs serves to suppress the type I interferon system of mammalian hosts. J Virol (2007) 1.90
Type I interferons directly regulate lymphocyte recirculation and cause transient blood lymphopenia. Blood (2006) 1.83
Detection of "Candidatus Neoehrlichia mikurensis" in two patients with severe febrile illnesses: evidence for a European sequence variant. J Clin Microbiol (2010) 1.82
Vaccination with plasmid DNA activates dendritic cells via Toll-like receptor 9 (TLR9) but functions in TLR9-deficient mice. J Immunol (2003) 1.81
Protective role of beta interferon in host defense against influenza A virus. J Virol (2006) 1.80
Macrophage-expressed IFN-β contributes to apoptotic alveolar epithelial cell injury in severe influenza virus pneumonia. PLoS Pathog (2013) 1.74
Novel reporter mouse reveals constitutive and inflammatory expression of IFN-beta in vivo. J Immunol (2009) 1.69
Organ-dependent in vivo priming of naive CD4+, but not CD8+, T cells by plasmacytoid dendritic cells. J Exp Med (2007) 1.68
IL-17-induced CXCL12 recruits B cells and induces follicle formation in BALT in the absence of differentiated FDCs. J Exp Med (2014) 1.67
Dendritic cells respond to influenza virus through TLR7- and PKR-independent pathways. Eur J Immunol (2005) 1.62
Hydrolytic reactivity trends among potential prodrugs of the O2-glycosylated diazeniumdiolate family. Targeting nitric oxide to macrophages for antileishmanial activity. J Med Chem (2008) 1.62
Key role of splenic myeloid DCs in the IFN-alphabeta response to adenoviruses in vivo. PLoS Pathog (2008) 1.58
Local type I IFN receptor signaling protects against virus spread within the central nervous system. J Immunol (2009) 1.57
Translational control of inducible nitric oxide synthase by IL-13 and arginine availability in inflammatory macrophages. J Immunol (2003) 1.54
Development of interleukin-17-producing γδ T cells is restricted to a functional embryonic wave. Immunity (2012) 1.52
Modified vaccinia virus Ankara induces Toll-like receptor-independent type I interferon responses. J Virol (2007) 1.50
Characterization of the interferon-producing cell in mice infected with Listeria monocytogenes. PLoS Pathog (2009) 1.50
Lethal varicella-zoster virus reactivation without skin lesions following renal transplantation. Nephrol Dial Transplant (2010) 1.49
Tumor invasion of Salmonella enterica serovar Typhimurium is accompanied by strong hemorrhage promoted by TNF-alpha. PLoS One (2009) 1.47
Cutting edge: central nervous system plasmacytoid dendritic cells regulate the severity of relapsing experimental autoimmune encephalomyelitis. J Immunol (2008) 1.47
Mammalian target of rapamycin (mTOR) orchestrates the defense program of innate immune cells. Eur J Immunol (2008) 1.46
TLR9 signaling is essential for the innate NK cell response in murine cutaneous leishmaniasis. Eur J Immunol (2007) 1.46
Active demethylation of the Foxp3 locus leads to the generation of stable regulatory T cells within the thymus. J Immunol (2013) 1.45
Type I IFN-mediated protection of macrophages and dendritic cells secures control of murine coronavirus infection. J Immunol (2009) 1.45
Systemic application of CpG-rich DNA suppresses adaptive T cell immunity via induction of IDO. Eur J Immunol (2006) 1.45
Activation of cannabinoid 2 receptors protects against cerebral ischemia by inhibiting neutrophil recruitment. FASEB J (2009) 1.44
Minute numbers of contaminant CD8+ T cells or CD11b+CD11c+ NK cells are the source of IFN-gamma in IL-12/IL-18-stimulated mouse macrophage populations. Blood (2004) 1.44
Containment of tumor-colonizing bacteria by host neutrophils. Cancer Res (2008) 1.42
Selectivity and efficiency of late transgene expression by transcriptionally targeted oncolytic adenoviruses are dependent on the transgene insertion strategy. Hum Gene Ther (2011) 1.41
High diversity of ankA sequences of Anaplasma phagocytophilum among Ixodes ricinus ticks in Germany. J Clin Microbiol (2003) 1.41
The innate immune response against Leishmania parasites. Immunobiology (2008) 1.39
Norovirus triggered microbiota-driven mucosal inflammation in interleukin 10-deficient mice. Inflamm Bowel Dis (2014) 1.38
Type I interferon signaling in dendritic cells stimulates the development of lymph-node-resident T follicular helper cells. Immunity (2009) 1.38
Tissue macrophages suppress viral replication and prevent severe immunopathology in an interferon-I-dependent manner in mice. Hepatology (2010) 1.33
Potentiation of epithelial innate host responses by intercellular communication. PLoS Pathog (2010) 1.31
Zinc signals are essential for lipopolysaccharide-induced signal transduction in monocytes. J Immunol (2008) 1.31
Mouse SAMHD1 has antiretroviral activity and suppresses a spontaneous cell-intrinsic antiviral response. Cell Rep (2013) 1.28
Murine toll-like receptor 2 activation induces type I interferon responses from endolysosomal compartments. PLoS One (2010) 1.28
High frequency of Tropheryma whipplei in culture-negative endocarditis. J Clin Microbiol (2011) 1.26
Vaccinia virus-mediated inhibition of type I interferon responses is a multifactorial process involving the soluble type I interferon receptor B18 and intracellular components. J Virol (2008) 1.26
Requirement for TLR9 in the immunomodulatory activity of Propionibacterium acnes. J Immunol (2005) 1.26
Type I interferon drives tumor necrosis factor-induced lethal shock. J Exp Med (2009) 1.25
Tuboovarian abscess caused by Atopobium vaginae following transvaginal oocyte recovery. J Clin Microbiol (2003) 1.25
Salmonella-allies in the fight against cancer. J Mol Med (Berl) (2010) 1.24
CpG-DNA aided cross-presentation of soluble antigens by dendritic cells. Eur J Immunol (2002) 1.23
Nitric oxide-mediated regulation of ferroportin-1 controls macrophage iron homeostasis and immune function in Salmonella infection. J Exp Med (2013) 1.22
Organ-specific and stage-dependent control of Leishmania major infection by inducible nitric oxide synthase and phagocyte NADPH oxidase. Eur J Immunol (2003) 1.22
Induction of B-cell development in adult mice reveals the ability of bone marrow to produce B-1a cells. Blood (2009) 1.21
Remote control of tumour-targeted Salmonella enterica serovar Typhimurium by the use of L-arabinose as inducer of bacterial gene expression in vivo. Cell Microbiol (2007) 1.21
TLR9 contributes to antiviral immunity during gammaherpesvirus infection. J Immunol (2008) 1.20
The Th17 cytokine IL-22 induces IL-20 production in keratinocytes: a novel immunological cascade with potential relevance in psoriasis. Eur J Immunol (2009) 1.19
Temporal and spatial resolution of type I and III interferon responses in vivo. J Virol (2010) 1.18
Type I IFN modulates host defense and late hyperinflammation in septic peritonitis. J Immunol (2006) 1.18
The cholesterol-dependent cytolysin listeriolysin O aggregates rafts via oligomerization. Cell Microbiol (2005) 1.18
CpG motif-independent activation of TLR9 upon endosomal translocation of "natural" phosphodiester DNA. Eur J Immunol (2006) 1.15
The multiple mechanisms of Ca2+ signalling by listeriolysin O, the cholesterol-dependent cytolysin of Listeria monocytogenes. Cell Microbiol (2007) 1.14
Effects of type I interferons on Friend retrovirus infection. J Virol (2006) 1.14
TGN1412--a regulator's perspective. Nat Biotechnol (2006) 1.13
Differential responses of immune cells to type I interferon contribute to host resistance to viral infection. Cell Host Microbe (2012) 1.12
Transcriptional activation induced in macrophages by Toll-like receptor (TLR) ligands: from expression profiling to a model of TLR signaling. Eur J Immunol (2004) 1.12
Protection against progressive leishmaniasis by IFN-beta. J Immunol (2004) 1.12
Synergistic and differential modulation of immune responses by Hsp60 and lipopolysaccharide. J Biol Chem (2006) 1.12