Published in Circulation on April 09, 2007
Heart disease and stroke statistics--2012 update: a report from the American Heart Association. Circulation (2011) 31.98
Heart disease and stroke statistics--2013 update: a report from the American Heart Association. Circulation (2012) 30.79
Heart disease and stroke statistics--2011 update: a report from the American Heart Association. Circulation (2010) 30.07
Heart disease and stroke statistics--2014 update: a report from the American Heart Association. Circulation (2013) 28.02
Metabolic syndrome: definitions and controversies. BMC Med (2011) 3.80
Heart Disease and Stroke Statistics-2017 Update: A Report From the American Heart Association. Circulation (2017) 2.76
Cardiac markers of pre-clinical disease in adolescents with the metabolic syndrome: the strong heart study. J Am Coll Cardiol (2008) 1.81
Best practice updates for pediatric/adolescent weight loss surgery. Obesity (Silver Spring) (2009) 1.71
Growth curves for cardio-metabolic risk factors in children and adolescents. J Pediatr (2009) 1.53
Atherogenic dyslipidemia in children: evaluation of clinical, biochemical and genetic aspects. PLoS One (2015) 1.40
What is metabolic syndrome, and why are children getting it? Ann N Y Acad Sci (2013) 1.38
Relation of blood pressure and body mass index during childhood to cardiovascular risk factor levels in young adults. J Hypertens (2009) 1.31
The stability of metabolic syndrome in children and adolescents. J Clin Endocrinol Metab (2009) 1.23
Synergy between adiposity, insulin resistance, metabolic risk factors, and inflammation in adolescents. Diabetes Care (2009) 1.06
Prevalence of metabolic syndrome in a cohort of Chinese schoolchildren: comparison of two definitions and assessment of adipokines as components by factor analysis. BMC Public Health (2013) 1.01
Does the built environment relate to the metabolic syndrome in adolescents? Health Place (2009) 0.97
Childhood predictors of the metabolic syndrome in middle-aged adults: the Muscatine study. J Pediatr (2009) 0.96
Metabolic syndrome risk factors in overweight, obese, and extremely obese Brazilian adolescents. Nutr J (2013) 0.96
Metabolic syndrome risk profiles among African American adolescents: national health and nutrition examination survey, 2003-2010. Diabetes Care (2012) 0.93
Predicting cardiovascular risk in young adulthood from the metabolic syndrome, its component risk factors, and a cluster score in childhood. Int J Pediatr Obes (2010) 0.92
Stability of the factor structure of the metabolic syndrome across pubertal development: confirmatory factor analyses of three alternative models. J Pediatr (2009) 0.92
The severity of the metabolic syndrome increases over time within individuals, independent of baseline metabolic syndrome status and medication use: The Atherosclerosis Risk in Communities Study. Atherosclerosis (2015) 0.89
Neck circumference as a predictor of metabolic syndrome, insulin resistance and low-grade systemic inflammation in children: the ACFIES study. BMC Pediatr (2016) 0.89
What do we know about metabolic syndrome in adolescents with PCOS? J Turk Ger Gynecol Assoc (2014) 0.88
High-sensitivity C-reactive protein is a predictive factor of adiposity in children: results of the identification and prevention of dietary- and lifestyle-induced health effects in children and infants (IDEFICS) study. J Am Heart Assoc (2013) 0.86
Social encounters in daily life and 2-year changes in metabolic risk factors in young women. Dev Psychopathol (2011) 0.86
Patterns of change in cardiometabolic risk factors associated with the metabolic syndrome among children and adolescents: the Fels Longitudinal Study. J Pediatr (2009) 0.85
Metabolic syndrome. Pediatr Rev (2012) 0.84
Insulin resistance. J Pediatr (2012) 0.84
Persistence of the metabolic syndrome over 3 annual visits in overweight Hispanic children: association with progressive risk for type 2 diabetes. J Pediatr (2009) 0.83
Hepatic steatosis and thyroid function tests in overweight and obese children. Int J Endocrinol (2013) 0.81
Pediatric obesity. An introduction. Appetite (2015) 0.81
Incidence and trend of a metabolic syndrome phenotype among Tehranian adolescents: findings from the Tehran Lipid and Glucose Study, 1998-2001 to 2003-2006. Diabetes Care (2010) 0.80
AMPK as Target for Intervention in Childhood and Adolescent Obesity. J Obes (2010) 0.79
Modifying cardiovascular risk in adolescent obesity. Circulation (2007) 0.78
Behind and beyond the pediatric metabolic syndrome. Ital J Pediatr (2009) 0.76
Management of obesity, insulin resistance and type 2 diabetes in children: consensus and controversy. Diabetes Metab Syndr Obes (2009) 0.76
A.S.P.E.N. clinical guidelines: nutrition support of hospitalized pediatric patients with obesity. JPEN J Parenter Enteral Nutr (2010) 0.75
The typology of metabolic syndrome in the transition to adulthood. J Clin Endocrinol Metab (2014) 0.75
The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents. Pediatrics (2004) 31.85
Prevalence and trends in overweight among US children and adolescents, 1999-2000. JAMA (2002) 23.79
The metabolic syndrome--a new worldwide definition. Lancet (2005) 23.51
A potential decline in life expectancy in the United States in the 21st century. N Engl J Med (2005) 19.63
The metabolic syndrome. Lancet (2005) 19.47
The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men. JAMA (2002) 18.43
Obesity and the metabolic syndrome in children and adolescents. N Engl J Med (2004) 13.99
The metabolic syndrome: time for a critical appraisal: joint statement from the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care (2005) 11.91
Prevalence of a metabolic syndrome phenotype in adolescents: findings from the third National Health and Nutrition Examination Survey, 1988-1994. Arch Pediatr Adolesc Med (2003) 8.54
Waist circumference percentiles in nationally representative samples of African-American, European-American, and Mexican-American children and adolescents. J Pediatr (2004) 7.08
Prevalence of the metabolic syndrome in American adolescents: findings from the Third National Health and Nutrition Examination Survey. Circulation (2004) 4.58
The metabolic syndrome: requiescat in pace. Clin Chem (2005) 4.50
Clinical management of metabolic syndrome: report of the American Heart Association/National Heart, Lung, and Blood Institute/American Diabetes Association conference on scientific issues related to management. Circulation (2004) 3.35
Frequency of abnormal carbohydrate metabolism and diabetes in a population-based screening of adolescents. J Pediatr (2005) 3.23
The metabolic syndrome in overweight Hispanic youth and the role of insulin sensitivity. J Clin Endocrinol Metab (2004) 3.20
Prevalence and characteristics of the metabolic syndrome in the San Antonio Heart and Framingham Offspring Studies. Diabetes (2003) 2.76
Prevalence and trends of a metabolic syndrome phenotype among u.s. Adolescents, 1999-2000. Diabetes Care (2004) 2.69
Distributions and trends of serum lipid levels among United States children and adolescents ages 4-19 years: data from the Third National Health and Nutrition Examination Survey. Prev Med (1999) 2.32
A single factor underlies the metabolic syndrome: a confirmatory factor analysis. Diabetes Care (2006) 2.22
Underdiagnosis of pediatric obesity and underscreening for fatty liver disease and metabolic syndrome by pediatricians and pediatric subspecialists. J Pediatr (2005) 2.15
Childhood obesity and type 2 diabetes mellitus. Pediatrics (2005) 2.08
The myth of the metabolic syndrome. Diabetologia (2005) 2.01
Risk variable clustering in the insulin resistance syndrome. The Framingham Offspring Study. Diabetes (1997) 1.88
Longitudinal changes in risk variables underlying metabolic Syndrome X from childhood to young adulthood in female subjects with a history of early menarche: the Bogalusa Heart Study. Int J Obes Relat Metab Disord (2003) 1.87
Metabolic syndrome scientific statement by the American Heart Association and the National Heart, Lung, and Blood Institute. Arterioscler Thromb Vasc Biol (2005) 1.76
Point: the metabolic syndrome still lives. Clin Chem (2005) 1.70
Obesity, metabolic syndrome, and coronary atherosclerosis. Circulation (2002) 1.56
Definition of metabolic syndrome in preadolescent girls. J Pediatr (2006) 1.56
Factor analysis of clustered cardiovascular risks in adolescence: obesity is the predominant correlate of risk among youth. Circulation (2005) 1.51
Social inequalities in biomarkers of cardiovascular risk in adolescence. Psychosom Med (2005) 1.48
The incidence and persistence of the NCEP (National Cholesterol Education Program) metabolic syndrome. The French D.E.S.I.R. study. Diabetes Metab (2003) 1.44
Relation of obesity to clustering of cardiovascular disease risk factors in children and young adults. The Bogalusa Heart Study. Am J Epidemiol (1987) 1.35
Hostility predicts metabolic syndrome risk factors in children and adolescents. Health Psychol (2003) 1.16
Impact of multiple cardiovascular risk factors on brachial artery distensibility in young adults: the Bogalusa Heart Study. Am J Hypertens (2005) 1.02
Sex and race differences in cardiovascular disease risk factor changes in schoolchildren, 1975-1990: the Princeton School Study. Am J Public Health (1999) 0.92
Use of lifestyle changes treatment plans and drug therapy in controlling cardiovascular and metabolic risk factors. Obesity (Silver Spring) (2006) 0.89
Does the metabolic syndrome really exist? Diabetes and heart disease groups spar over issue. JAMA (2005) 0.83
Importance of diagnosing and treating the metabolic syndrome in reducing cardiovascular risk. Obesity (Silver Spring) (2006) 0.83
Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation (2005) 43.74
Heart disease and stroke statistics--2011 update: a report from the American Heart Association. Circulation (2010) 30.07
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet (2010) 16.96
Evidence based physical activity for school-age youth. J Pediatr (2005) 13.50
Abdominal visceral and subcutaneous adipose tissue compartments: association with metabolic risk factors in the Framingham Heart Study. Circulation (2007) 12.79
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet (2009) 12.19
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet (2012) 11.09
Variants in MTNR1B influence fasting glucose levels. Nat Genet (2008) 10.85
Prediction of incident diabetes mellitus in middle-aged adults: the Framingham Offspring Study. Arch Intern Med (2007) 8.59
Metabolic syndrome as a precursor of cardiovascular disease and type 2 diabetes mellitus. Circulation (2005) 8.54
Childhood adiposity, adult adiposity, and cardiovascular risk factors. N Engl J Med (2011) 7.16
Decline in physical activity in black girls and white girls during adolescence. N Engl J Med (2002) 7.06
Overweight in children and adolescents: pathophysiology, consequences, prevention, and treatment. Circulation (2005) 7.04
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet (2010) 6.66
Lipid screening and cardiovascular health in childhood. Pediatrics (2008) 6.62
Soft drink consumption and risk of developing cardiometabolic risk factors and the metabolic syndrome in middle-aged adults in the community. Circulation (2007) 6.34
Dietary approaches to prevent and treat hypertension: a scientific statement from the American Heart Association. Hypertension (2006) 5.59
Visceral and subcutaneous adipose tissue volumes are cross-sectionally related to markers of inflammation and oxidative stress: the Framingham Heart Study. Circulation (2007) 5.10
The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports. BMC Med Genet (2007) 5.02
Bariatric surgery for severely overweight adolescents: concerns and recommendations. Pediatrics (2004) 5.01
Serum aldosterone and the incidence of hypertension in nonhypertensive persons. N Engl J Med (2004) 4.92
Association of smoking cessation and weight change with cardiovascular disease among adults with and without diabetes. JAMA (2013) 4.81
Trends in cardiovascular complications of diabetes. JAMA (2004) 4.74
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet (2012) 4.73
Inflammatory markers and risk of developing type 2 diabetes in women. Diabetes (2004) 4.67
Relation between the changes in physical activity and body-mass index during adolescence: a multicentre longitudinal study. Lancet (2005) 4.65
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet (2012) 4.37
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet (2014) 4.13
Low-grade albuminuria and incidence of cardiovascular disease events in nonhypertensive and nondiabetic individuals: the Framingham Heart Study. Circulation (2005) 4.08
Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways. Diabetes (2010) 4.07
Body iron stores in relation to risk of type 2 diabetes in apparently healthy women. JAMA (2004) 4.04
Increasing cardiovascular disease burden due to diabetes mellitus: the Framingham Heart Study. Circulation (2007) 3.99
Guidelines for lipid screening in children and adolescents: bringing evidence to the debate. Pediatrics (2012) 3.98
A randomized trial comparing a very low carbohydrate diet and a calorie-restricted low fat diet on body weight and cardiovascular risk factors in healthy women. J Clin Endocrinol Metab (2003) 3.93
Quality of diabetes care in U.S. academic medical centers: low rates of medical regimen change. Diabetes Care (2005) 3.93
Major dietary patterns are related to plasma concentrations of markers of inflammation and endothelial dysfunction. Am J Clin Nutr (2004) 3.61
Fatty liver is associated with dyslipidemia and dysglycemia independent of visceral fat: the Framingham Heart Study. Hepatology (2010) 3.60
Diet-quality scores and plasma concentrations of markers of inflammation and endothelial dysfunction. Am J Clin Nutr (2005) 3.55
Trends in the incidence of type 2 diabetes mellitus from the 1970s to the 1990s: the Framingham Heart Study. Circulation (2006) 3.41
Depression, self-care, and medication adherence in type 2 diabetes: relationships across the full range of symptom severity. Diabetes Care (2007) 3.40
Neck circumference as a novel measure of cardiometabolic risk: the Framingham Heart study. J Clin Endocrinol Metab (2010) 3.39
Carbohydrate nutrition, insulin resistance, and the prevalence of the metabolic syndrome in the Framingham Offspring Cohort. Diabetes Care (2004) 3.37
Effect of aging on A1C levels in individuals without diabetes: evidence from the Framingham Offspring Study and the National Health and Nutrition Examination Survey 2001-2004. Diabetes Care (2008) 3.33
C-reactive protein, the metabolic syndrome, and prediction of cardiovascular events in the Framingham Offspring Study. Circulation (2004) 3.25
Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes. Hum Mol Genet (2010) 3.24
Frequency of abnormal carbohydrate metabolism and diabetes in a population-based screening of adolescents. J Pediatr (2005) 3.23
Noninvasive assessment of subclinical atherosclerosis in children and adolescents: recommendations for standard assessment for clinical research: a scientific statement from the American Heart Association. Hypertension (2009) 3.22
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Correlates of beverage intake in adolescent girls: the National Heart, Lung, and Blood Institute Growth and Health Study. J Pediatr (2006) 3.15
Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. PLoS Genet (2011) 3.07
Tests of glycemia for the diagnosis of type 2 diabetes mellitus. Ann Intern Med (2002) 3.06
Association of C-reactive protein and HIV infection with acute myocardial infarction. J Acquir Immune Defic Syndr (2009) 2.99
Diagnosis and management of the metabolic syndrome. An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Executive summary. Cardiol Rev (2006) 2.99
Population approaches to improve diet, physical activity, and smoking habits: a scientific statement from the American Heart Association. Circulation (2012) 2.95
Blockade of receptor activator of nuclear factor-κB (RANKL) signaling improves hepatic insulin resistance and prevents development of diabetes mellitus. Nat Med (2013) 2.93
Population-based incidence rates and risk factors for type 2 diabetes in white individuals: the Bruneck study. Diabetes (2004) 2.89
Racial differences in the relation between uncoupling protein genes and resting energy expenditure. Am J Clin Nutr (2002) 2.84
Sequence kernel association test for quantitative traits in family samples. Genet Epidemiol (2012) 2.82
Dietary pattern, inflammation, and incidence of type 2 diabetes in women. Am J Clin Nutr (2005) 2.82
Impact of glucose intolerance and insulin resistance on cardiac structure and function: sex-related differences in the Framingham Heart Study. Circulation (2003) 2.80
Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium. Circulation (2010) 2.78
Severe obesity in children and adolescents: identification, associated health risks, and treatment approaches: a scientific statement from the American Heart Association. Circulation (2013) 2.71
CUBN is a gene locus for albuminuria. J Am Soc Nephrol (2011) 2.70
Impact of impaired fasting glucose on cardiovascular disease: the Framingham Heart Study. J Am Coll Cardiol (2008) 2.64
A 100K genome-wide association scan for diabetes and related traits in the Framingham Heart Study: replication and integration with other genome-wide datasets. Diabetes (2007) 2.60
Presence of diabetic ketoacidosis at diagnosis of diabetes mellitus in youth: the Search for Diabetes in Youth Study. Pediatrics (2008) 2.56
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. Am J Hum Genet (2012) 2.53
American Heart Association guidelines for primary prevention of atherosclerotic cardiovascular disease beginning in childhood. Circulation (2003) 2.51
Sex disparities in treatment of cardiac risk factors in patients with type 2 diabetes. Diabetes Care (2005) 2.45
Variant of transcription factor 7-like 2 (TCF7L2) gene and the risk of type 2 diabetes in large cohorts of U.S. women and men. Diabetes (2006) 2.45
Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans. Diabetes (2010) 2.44
Abdominal subcutaneous and visceral adipose tissue and insulin resistance in the Framingham heart study. Obesity (Silver Spring) (2010) 2.42
Parental report of outdoor playtime as a measure of physical activity in preschool-aged children. Arch Pediatr Adolesc Med (2004) 2.41
Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute scientific statement. Curr Opin Cardiol (2006) 2.41
Plasma 25-hydroxyvitamin d is associated with markers of the insulin resistant phenotype in nondiabetic adults. J Nutr (2008) 2.39
Effect of blinded peer review on abstract acceptance. JAMA (2006) 2.38
Effects of sibutramine treatment in obese adolescents: a randomized trial. Ann Intern Med (2006) 2.38
Dietary recommendations for children and adolescents: a guide for practitioners. Pediatrics (2006) 2.36
Twenty-four-hour ambulatory blood pressure in children with sleep-disordered breathing. Am J Respir Crit Care Med (2004) 2.34
Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. PLoS Genet (2012) 2.34
Relationship between elevated arterial stiffness and increased left ventricular mass in adolescents and young adults. J Pediatr (2011) 2.34
Relations of biomarkers of distinct pathophysiological pathways and atrial fibrillation incidence in the community. Circulation (2010) 2.32
Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute scientific statement: Executive Summary. Crit Pathw Cardiol (2005) 2.31
Cardiovascular disease risk factors in chronic kidney disease: overall burden and rates of treatment and control. Arch Intern Med (2006) 2.28
Impact of objective and subjective social status on obesity in a biracial cohort of adolescents. Obes Res (2003) 2.24
Whole-grain intake is favorably associated with metabolic risk factors for type 2 diabetes and cardiovascular disease in the Framingham Offspring Study. Am J Clin Nutr (2002) 2.23
Relationship between patient medication adherence and subsequent clinical inertia in type 2 diabetes glycemic management. Diabetes Care (2007) 2.22