Published in Int J Biochem Cell Biol on June 06, 2007
Deciphering the splicing code. Nature (2010) 6.27
Sox2(+) adult stem and progenitor cells are important for tissue regeneration and survival of mice. Cell Stem Cell (2011) 4.29
SOX5 postmitotically regulates migration, postmigratory differentiation, and projections of subplate and deep-layer neocortical neurons. Proc Natl Acad Sci U S A (2008) 2.26
Copy number variation in intron 1 of SOX5 causes the Pea-comb phenotype in chickens. PLoS Genet (2009) 2.10
L-Sox5 and Sox6 drive expression of the aggrecan gene in cartilage by securing binding of Sox9 to a far-upstream enhancer. Mol Cell Biol (2008) 2.07
The three SoxC proteins--Sox4, Sox11 and Sox12--exhibit overlapping expression patterns and molecular properties. Nucleic Acids Res (2008) 1.70
Transcriptome analysis of mammary epithelial subpopulations identifies novel determinants of lineage commitment and cell fate. BMC Genomics (2008) 1.70
The human airway epithelial basal cell transcriptome. PLoS One (2011) 1.69
Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors. Nat Commun (2010) 1.69
The cell-intrinsic requirement of Sox6 for cortical interneuron development. Neuron (2009) 1.66
Sox2 maintains self renewal of tumor-initiating cells in osteosarcomas. Oncogene (2011) 1.66
Integrated genetic approaches identify the molecular mechanisms of Sox4 in early B-cell development: intricate roles for RAG1/2 and CK1ε. Blood (2014) 1.56
Codependent activators direct myoblast-specific MyoD transcription. Dev Cell (2008) 1.52
SOX9 expression and its methylation status in gastric cancer. Virchows Arch (2012) 1.47
Orchestrating transcriptional control of adult neurogenesis. Genes Dev (2012) 1.41
A genetic pathway composed of Sox14 and Mical governs severing of dendrites during pruning. Nat Neurosci (2009) 1.38
An EGFR-ERK-SOX9 signaling cascade links urothelial development and regeneration to cancer. Cancer Res (2011) 1.37
SOX9: a stem cell transcriptional regulator of secreted niche signaling factors. Genes Dev (2014) 1.34
Sox2 induces neuronal formation in the developing mammalian cochlea. J Neurosci (2010) 1.32
Sox9 plays multiple roles in the lung epithelium during branching morphogenesis. Proc Natl Acad Sci U S A (2013) 1.29
Exportin 4 mediates a novel nuclear import pathway for Sox family transcription factors. J Cell Biol (2009) 1.22
The genetics of sex differences in brain and behavior. Front Neuroendocrinol (2010) 1.21
The transcription factor Sox4 is a downstream target of signaling by the cytokine TGF-β and suppresses T(H)2 differentiation. Nat Immunol (2012) 1.18
The transcription factor Sox5 modulates Sox10 function during melanocyte development. Nucleic Acids Res (2008) 1.16
The transcription factor Sox2 is required for osteoblast self-renewal. Cell Death Differ (2010) 1.16
Multiple transcription factor families regulate axon growth and regeneration. Dev Neurobiol (2011) 1.13
High SOX2 levels predict better outcome in non-small cell lung carcinomas. PLoS One (2013) 1.13
VEGF and RANKL regulation of NFATc1 in heart valve development. Circ Res (2009) 1.11
Prognostic significance of Sox4 expression in human cutaneous melanoma and its role in cell migration and invasion. Am J Pathol (2010) 1.08
Gene expression profiling and chromatin immunoprecipitation identify DBN1, SETMAR and HIG2 as direct targets of SOX11 in mantle cell lymphoma. PLoS One (2010) 1.08
The high mobility group box: the ultimate utility player of a cell. Trends Biochem Sci (2012) 1.05
Transcriptional regulation of endothelial cell and vascular development. Circ Res (2013) 1.03
CARM1 mediates modulation of Sox2. PLoS One (2011) 1.03
Transcription factors SOX4 and SOX11 function redundantly to regulate the development of mouse retinal ganglion cells. J Biol Chem (2013) 1.02
Rho kinase-dependent activation of SOX9 in chondrocytes. Arthritis Rheum (2010) 1.02
Expression and functional role of Sox9 in human epidermal keratinocytes. PLoS One (2013) 1.00
Sox9 and programming of liver and pancreatic progenitors. J Clin Invest (2013) 1.00
Multiple Sox genes are expressed in stem cells or in differentiating neuro-sensory cells in the hydrozoan Clytia hemisphaerica. Evodevo (2011) 0.99
SOX7: from a developmental regulator to an emerging tumor suppressor. Histol Histopathol (2013) 0.99
Lineage specification of Flk-1+ progenitors is associated with divergent Sox7 expression in cardiopoiesis. Differentiation (2008) 0.99
Epigenetic activation of SOX11 in lymphoid neoplasms by histone modifications. PLoS One (2011) 0.98
A comparison of stem cell-related gene expression in the progenitor-rich limbal epithelium and the differentiating central corneal epithelium. Mol Vis (2011) 0.95
SLUG is required for SOX9 stabilization and functions to promote cancer stem cells and metastasis in human lung carcinoma. Oncogene (2015) 0.95
Distinct Transcriptional Programs Underlie Sox9 Regulation of the Mammalian Chondrocyte. Cell Rep (2015) 0.95
Parallel expansions of Sox transcription factor group B predating the diversifications of the arthropods and jawed vertebrates. PLoS One (2011) 0.95
Integrative analyses of gene expression and DNA methylation profiles in breast cancer cell line models of tamoxifen-resistance indicate a potential role of cells with stem-like properties. Breast Cancer Res (2013) 0.94
Neurodevelopment genes in lampreys reveal trends for forebrain evolution in craniates. PLoS One (2009) 0.94
Stage-specific control of connective tissue growth factor (CTGF/CCN2) expression in chondrocytes by Sox9 and beta-catenin. J Biol Chem (2010) 0.93
Evolutionarily conserved, growth plate zone-specific regulation of the matrilin-1 promoter: L-Sox5/Sox6 and Nfi factors bound near TATA finely tune activation by Sox9. Mol Cell Biol (2010) 0.93
Transcriptome sequencing and annotation of the predatory mite Metaseiulus occidentalis (Acari: Phytoseiidae): a cautionary tale about possible contamination by prey sequences. Exp Appl Acarol (2012) 0.91
Genome-wide analysis of the sox family in the calcareous sponge Sycon ciliatum: multiple genes with unique expression patterns. Evodevo (2012) 0.90
Increased Sox2 copy number in lung squamous cell carcinomas. Exp Ther Med (2011) 0.90
The transcription factor protein Sox11 enhances early osteoblast differentiation by facilitating proliferation and the survival of mesenchymal and osteoblast progenitors. J Biol Chem (2013) 0.90
Cardiogenol C can induce Mouse Hair Bulge Progenitor Cells to Transdifferentiate into Cardiomyocyte-like Cells. Proteome Sci (2011) 0.89
Calmodulin-dependent nuclear import of HMG-box family nuclear factors: importance of the role of SRY in sex reversal. Biochem J (2010) 0.89
Mapping of DNA sex-specific markers and genes related to sex differentiation in turbot (Scophthalmus maximus). Mar Biotechnol (NY) (2012) 0.89
The transcription factor Sox11 promotes nerve regeneration through activation of the regeneration-associated gene Sprr1a. Exp Neurol (2011) 0.88
Progression of neurogenesis in the inner ear requires inhibition of Sox2 transcription by neurogenin1 and neurod1. J Neurosci (2013) 0.88
A functional RANKL polymorphism associated with younger age at onset of rheumatoid arthritis. Arthritis Rheum (2010) 0.87
Postmitotic diversification of olfactory neuron types is mediated by differential activities of the HMG-box transcription factor SOX-2. EMBO J (2015) 0.87
Sox11 modulates brain-derived neurotrophic factor expression in an exon promoter-specific manner. J Neurosci Res (2012) 0.86
Sox9 potentiates BMP2-induced chondrogenic differentiation and inhibits BMP2-induced osteogenic differentiation. PLoS One (2014) 0.85
Sox4 links tumor suppression to accelerated aging in mice by modulating stem cell activation. Cell Rep (2014) 0.84
Peroxisome-proliferator-activated receptor-binding protein (PBP) is essential for the growth of active Notch4-immortalized mammary epithelial cells by activating SOX10 expression. Biochem J (2009) 0.84
SOX9 is targeted for proteasomal degradation by the E3 ligase FBW7 in response to DNA damage. Nucleic Acids Res (2016) 0.83
Characterization, phylogeny, alternative splicing and expression of Sox30 gene. BMC Mol Biol (2010) 0.83
Orchestration of Neuronal Differentiation and Progenitor Pool Expansion in the Developing Cortex by SoxC Genes. J Neurosci (2015) 0.82
Analysis of SOX2-expressing cell populations derived from human pluripotent stem cells. Stem Cell Reports (2013) 0.81
Promoter methylation status of the tumor suppressor gene SOX11 is associated with cell growth and invasion in nasopharyngeal carcinoma. Cancer Cell Int (2013) 0.81
Antagonistic cross-regulation between Sox9 and Sox10 controls an anti-tumorigenic program in melanoma. PLoS Genet (2015) 0.81
Transcriptional dysregulation of neocortical circuit assembly in ASD. Int Rev Neurobiol (2013) 0.81
Genomic analysis of the Pacific oyster (Crassostrea gigas) reveals possible conservation of vertebrate sex determination in a mollusc. G3 (Bethesda) (2014) 0.80
Sox9 confers stemness properties in hepatocellular carcinoma through Frizzled-7 mediated Wnt/β-catenin signaling. Oncotarget (2016) 0.80
Ectopic expression of mouse Sry interferes with Wnt/beta-catenin signaling in mouse embryonal carcinoma cell lines. Biochim Biophys Acta (2008) 0.80
A highly conserved SOX6 double binding site mediates SOX6 gene downregulation in erythroid cells. Nucleic Acids Res (2010) 0.80
Unique establishment of procephalic head segments is supported by the identification of cis-regulatory elements driving segment-specific segment polarity gene expression in Drosophila. Dev Genes Evol (2011) 0.80
70-kDa heat shock cognate protein hsc70 mediates calmodulin-dependent nuclear import of the sex-determining factor SRY. J Biol Chem (2012) 0.80
Expression of pluripotency factors in echinoderm regeneration. Cell Tissue Res (2014) 0.80
RanBPM expression regulates transcriptional pathways involved in development and tumorigenesis. Am J Cancer Res (2012) 0.80
Silencing of SOX12 by shRNA suppresses migration, invasion and proliferation of breast cancer cells. Biosci Rep (2016) 0.78
SoxC transcription factors are essential for the development of the inner ear. Proc Natl Acad Sci U S A (2015) 0.78
Ube2s regulates Sox2 stability and mouse ES cell maintenance. Cell Death Differ (2015) 0.78
Loss of SOX9 Expression Is Associated with PSA Recurrence in ERG-Positive and PTEN Deleted Prostate Cancers. PLoS One (2015) 0.78
Wnt signaling in triple-negative breast cancer. Oncogenesis (2017) 0.78
Zebrafish Her8a is activated by Su(H)-dependent Notch signaling and is essential for the inhibition of neurogenesis. PLoS One (2011) 0.77
The reprogrammed pancreatic progenitor-like intermediate state of hepatic cells is more susceptible to pancreatic beta cell differentiation. J Cell Sci (2013) 0.77
Dbx1 is a direct target of SOX3 in the spinal cord. PLoS One (2014) 0.77
DNA methylation and histone modifications regulate SOX11 expression in lymphoid and solid cancer cells. BMC Cancer (2015) 0.77
Genetic association study of UCMA/GRP and OPTN genes (PDB6 locus) with Paget's disease of bone. Bone (2012) 0.77
High levels of SOX5 decrease proliferative capacity of human B cells, but permit plasmablast differentiation. PLoS One (2014) 0.77
SOX9 is a novel cancer stem cell marker surrogated by osteopontin in human hepatocellular carcinoma. Sci Rep (2016) 0.76
Repression of TIF1γ by SOX2 promotes TGF-β-induced epithelial-mesenchymal transition in non-small-cell lung cancer. Oncogene (2015) 0.76
RNAi silencing of the SoxE gene suppresses cell proliferation in silkworm BmN4 cells. Mol Biol Rep (2014) 0.76
SOXC Genes and the Control of Skeletogenesis. Curr Osteoporos Rep (2016) 0.75
SOX9 accelerates ESC differentiation to three germ layer lineages by repressing SOX2 expression through P21 (WAF1/CIP1). Development (2014) 0.75
Genome-Wide Identification and Transcriptome-Based Expression Profiling of the Sox Gene Family in the Nile Tilapia (Oreochromis niloticus). Int J Mol Sci (2016) 0.75
Dimerization and Transactivation Domains as Candidates for Functional Modulation and Diversity of Sox9. PLoS One (2016) 0.75
The sox gene Dichaete is expressed in local interneurons and functions in development of the Drosophila adult olfactory circuit. Dev Neurobiol (2012) 0.75
Sox9 and Sox8 protect the adult testis from male-to-female genetic reprogramming and complete degeneration. Elife (2016) 0.75
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell (2006) 120.51
Multipotent cell lineages in early mouse development depend on SOX2 function. Genes Dev (2003) 12.38
A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif. Nature (1990) 10.97
The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6. Genes Dev (2002) 8.19
A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes. Nature (1990) 7.93
Sox9 is required for cartilage formation. Nat Genet (1999) 7.89
Male development of chromosomally female mice transgenic for Sry. Nature (1991) 7.73
SOX2 functions to maintain neural progenitor identity. Neuron (2003) 7.48
Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene SOX9. Cell (1994) 7.39
Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene. Nature (1994) 7.30
LEF-1, a gene encoding a lymphoid-specific protein with an HMG domain, regulates T-cell receptor alpha enhancer function [corrected]. Genes Dev (1991) 5.95
SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen gene. Mol Cell Biol (1997) 5.72
Vertebrate neurogenesis is counteracted by Sox1-3 activity. Nat Neurosci (2003) 5.65
HMG domain proteins: architectural elements in the assembly of nucleoprotein structures. Trends Genet (1994) 5.43
Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox2 and Oct-3. Genes Dev (1995) 5.42
A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene. EMBO J (1998) 5.15
Mutations in SOX2 cause anophthalmia. Nat Genet (2003) 5.03
Regulation of DNA-dependent activities by the functional motifs of the high-mobility-group chromosomal proteins. Mol Cell Biol (1999) 4.91
From head to toes: the multiple facets of Sox proteins. Nucleic Acids Res (1999) 4.64
The transcription factor Sox10 is a key regulator of peripheral glial development. Genes Dev (2001) 4.40
Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions. Genes Dev (1995) 4.34
SOX9 is required for maintenance of the pancreatic progenitor cell pool. Proc Natl Acad Sci U S A (2007) 4.19
Depletion of definitive gut endoderm in Sox17-null mutant mice. Development (2002) 4.13
The transcription factors L-Sox5 and Sox6 are essential for cartilage formation. Dev Cell (2001) 4.11
Sox9 is essential for outer root sheath differentiation and the formation of the hair stem cell compartment. Curr Biol (2005) 4.04
Sox10, a novel transcriptional modulator in glial cells. J Neurosci (1998) 3.96
Phylogeny of the SOX family of developmental transcription factors based on sequence and structural indicators. Dev Biol (2000) 3.90
SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse. Dev Biol (1997) 3.84
Pairing SOX off: with partners in the regulation of embryonic development. Trends Genet (2000) 3.82
SOX10 mutations in patients with Waardenburg-Hirschsprung disease. Nat Genet (1998) 3.82
Sox2 deficiency causes neurodegeneration and impaired neurogenesis in the adult mouse brain. Development (2004) 3.75
Structural basis for DNA bending by the architectural transcription factor LEF-1. Nature (1995) 3.58
Sox10 mutation disrupts neural crest development in Dom Hirschsprung mouse model. Nat Genet (1998) 3.51
The Sox9 transcription factor determines glial fate choice in the developing spinal cord. Genes Dev (2003) 3.46
The Sry-related gene Sox9 is expressed during chondrogenesis in mouse embryos. Nat Genet (1995) 3.45
Twenty pairs of sox: extent, homology, and nomenclature of the mouse and human sox transcription factor gene families. Dev Cell (2002) 3.39
Molecular basis of human 46X,Y sex reversal revealed from the three-dimensional solution structure of the human SRY-DNA complex. Cell (1995) 3.35
Parallel expression of Sox9 and Col2a1 in cells undergoing chondrogenesis. Dev Dyn (1997) 3.35
Functional analysis of Sox8 and Sox9 during sex determination in the mouse. Development (2004) 3.25
Sox9 expression during gonadal development implies a conserved role for the gene in testis differentiation in mammals and birds. Nat Genet (1996) 3.11
From stem cells to neurons and glia: a Soxist's view of neural development. Trends Neurosci (2005) 3.07
A comparison of the properties of Sox-3 with Sry and two related genes, Sox-1 and Sox-2. Development (1996) 3.02
Crystal structure of a POU/HMG/DNA ternary complex suggests differential assembly of Oct4 and Sox2 on two enhancers. Genes Dev (2003) 2.99
Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10. Genes Dev (2002) 2.98
A new group of chromatin-associated proteins with a high content of acidic and basic amino acids. Eur J Biochem (1973) 2.92
Defects in cardiac outflow tract formation and pro-B-lymphocyte expansion in mice lacking Sox-4. Nature (1996) 2.91
Sox-4, an Sry-like HMG box protein, is a transcriptional activator in lymphocytes. EMBO J (1993) 2.85
The transcriptional control of trunk neural crest induction, survival, and delamination. Dev Cell (2005) 2.67
Transcriptional control of chondrocyte fate and differentiation. Birth Defects Res C Embryo Today (2005) 2.67
Sox9 is required for determination of the chondrogenic cell lineage in the cranial neural crest. Proc Natl Acad Sci U S A (2003) 2.64
Interaction among SOX10, PAX3 and MITF, three genes altered in Waardenburg syndrome. Hum Mol Genet (2000) 2.63
Rapid sequence evolution of the mammalian sex-determining gene SRY. Nature (1993) 2.52
The DNA-binding specificity of SOX9 and other SOX proteins. Nucleic Acids Res (1999) 2.50
Identification of Sox-2 regulatory region which is under the control of Oct-3/4-Sox-2 complex. Nucleic Acids Res (2002) 2.49
Direct interaction of SRY-related protein SOX9 and steroidogenic factor 1 regulates transcription of the human anti-Müllerian hormone gene. Mol Cell Biol (1998) 2.44
Definition of a consensus DNA binding site for SRY. Nucleic Acids Res (1994) 2.34
Sox1 directly regulates the gamma-crystallin genes and is essential for lens development in mice. Genes Dev (1998) 2.33
Sox17 and beta-catenin cooperate to regulate the transcription of endodermal genes. Development (2004) 2.33
Mutations within Sox2/SOX2 are associated with abnormalities in the hypothalamo-pituitary-gonadal axis in mice and humans. J Clin Invest (2006) 2.27
A conserved family of genes related to the testis determining gene, SRY. Nucleic Acids Res (1992) 2.26
Matching SOX: partner proteins and co-factors of the SOX family of transcriptional regulators. Curr Opin Genet Dev (2002) 2.24
Gene targeting reveals a widespread role for the high-mobility-group transcription factor Sox11 in tissue remodeling. Mol Cell Biol (2004) 2.23
The establishment of neuronal properties is controlled by Sox4 and Sox11. Genes Dev (2006) 2.21
SOX genes and neural progenitor identity. Curr Opin Neurobiol (2005) 2.18
Pax6 and SOX2 form a co-DNA-binding partner complex that regulates initiation of lens development. Genes Dev (2001) 2.18
Mutations in SOX2 cause anophthalmia-esophageal-genital (AEG) syndrome. Hum Mol Genet (2006) 2.17
Mutation of the Sry-related Sox10 gene in Dominant megacolon, a mouse model for human Hirschsprung disease. Proc Natl Acad Sci U S A (1998) 2.15
Involvement of Sox1, 2 and 3 in the early and subsequent molecular events of lens induction. Development (1998) 2.11
Mutations in the transcription factor gene SOX18 underlie recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia. Am J Hum Genet (2003) 2.10
The combination of SOX5, SOX6, and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage. Arthritis Rheum (2004) 2.08
Two distinct subgroups of Group B Sox genes for transcriptional activators and repressors: their expression during embryonic organogenesis of the chicken. Mech Dev (1999) 2.07
Redundant roles of Sox17 and Sox18 in postnatal angiogenesis in mice. J Cell Sci (2006) 2.05
Direct regulation of adult brain function by the male-specific factor SRY. Curr Biol (2006) 2.05
Seven new members of the Sox gene family expressed during mouse development. Nucleic Acids Res (1993) 2.03
SOX2 functions in adult neural stem cells. Trends Neurosci (2005) 2.01
Interplay of SOX and POU factors in regulation of the Nestin gene in neural primordial cells. Mol Cell Biol (2004) 2.00
SOX3 is required during the formation of the hypothalamo-pituitary axis. Nat Genet (2004) 1.99
Xsox17alpha and -beta mediate endoderm formation in Xenopus. Cell (1997) 1.97
Sox2 is required for development of taste bud sensory cells. Genes Dev (2006) 1.97
A transgenic insertion upstream of sox9 is associated with dominant XX sex reversal in the mouse. Nat Genet (2000) 1.95
The structure of a chromosomal high mobility group protein-DNA complex reveals sequence-neutral mechanisms important for non-sequence-specific DNA recognition. EMBO J (1999) 1.91
The glial transcription factor Sox10 binds to DNA both as monomer and dimer with different functional consequences. Nucleic Acids Res (2000) 1.91
Requirement of Sox2-mediated signaling for differentiation of early Xenopus neuroectoderm. Development (2000) 1.83
SRY and sex determination in mammals. Annu Rev Genet (1993) 1.82
The chondrogenic transcription factor Sox9 is a target of signaling by the parathyroid hormone-related peptide in the growth plate of endochondral bones. Proc Natl Acad Sci U S A (2001) 1.81
Sex-reversing mutations affect the architecture of SRY-DNA complexes. EMBO J (1994) 1.80
SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function. Dev Cell (2006) 1.79
Transcriptional co-activators CREB-binding protein and p300 regulate chondrocyte-specific gene expression via association with Sox9. J Biol Chem (2003) 1.79
Essential role of Sox9 in the pathway that controls formation of cardiac valves and septa. Proc Natl Acad Sci U S A (2004) 1.77
Sex reversal by loss of the C-terminal transactivation domain of human SOX9. Nat Genet (1996) 1.76
Upwardly mobile proteins. Workshop: the role of HMG proteins in chromatin structure, gene expression and neoplasia. EMBO Rep (2000) 1.76
Dimerization of SOX9 is required for chondrogenesis, but not for sex determination. Hum Mol Genet (2003) 1.74
Regulation of gammadelta versus alphabeta T lymphocyte differentiation by the transcription factor SOX13. Science (2007) 1.71
SOX7 transcription factor: sequence, chromosomal localisation, expression, transactivation and interference with Wnt signalling. Nucleic Acids Res (2001) 1.71
Sox21 promotes the progression of vertebrate neurogenesis. Nat Neurosci (2005) 1.70
Sox-4 facilitates thymocyte differentiation. Eur J Immunol (1997) 1.67
Transcription factors Sox8 and Sox10 perform non-equivalent roles during oligodendrocyte development despite functional redundancy. Development (2004) 1.66
Two independent nuclear localization signals are present in the DNA-binding high-mobility group domains of SRY and SOX9. J Biol Chem (1997) 1.64
An 18-base-pair sequence in the mouse proalpha1(II) collagen gene is sufficient for expression in cartilage and binds nuclear proteins that are selectively expressed in chondrocytes. Mol Cell Biol (1996) 1.64
The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors. Nucleic Acids Res (2006) 1.64
DNA methylation markers and early recurrence in stage I lung cancer. N Engl J Med (2008) 5.87
Eltrombopag and improved hematopoiesis in refractory aplastic anemia. N Engl J Med (2012) 3.93
Simultaneous phase and size control of upconversion nanocrystals through lanthanide doping. Nature (2010) 3.53
Somatic Mutations and Clonal Hematopoiesis in Aplastic Anemia. N Engl J Med (2015) 3.42
Tuning upconversion through energy migration in core-shell nanoparticles. Nat Mater (2011) 2.00
Eltrombopag restores trilineage hematopoiesis in refractory severe aplastic anemia that can be sustained on discontinuation of drug. Blood (2013) 1.97
Promoter hypermethylation of resected bronchial margins: a field defect of changes? Clin Cancer Res (2004) 1.93
Thymus-derived rather than tumor-induced regulatory T cells predominate in brain tumors. Neuro Oncol (2011) 1.89
Tomato transcription factors pti4, pti5, and pti6 activate defense responses when expressed in Arabidopsis. Plant Cell (2002) 1.86
Hippo signaling regulates differentiation and maintenance in the exocrine pancreas. Gastroenterology (2013) 1.85
Prolongation of survival following depletion of CD4+CD25+ regulatory T cells in mice with experimental brain tumors. J Neurosurg (2006) 1.73
The three SoxC proteins--Sox4, Sox11 and Sox12--exhibit overlapping expression patterns and molecular properties. Nucleic Acids Res (2008) 1.70
Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors. Nat Commun (2010) 1.69
IDO expression in brain tumors increases the recruitment of regulatory T cells and negatively impacts survival. Clin Cancer Res (2012) 1.55
Regulation of renalase expression by D5 dopamine receptors in rat renal proximal tubule cells. Am J Physiol Renal Physiol (2014) 1.50
Survivin-driven and fiber-modified oncolytic adenovirus exhibits potent antitumor activity in established intracranial glioma. Hum Gene Ther (2007) 1.48
Hypermethylation of the GATA genes in lung cancer. Clin Cancer Res (2004) 1.45
Melanoma B16-F1 cells coated with fusion protein of mouse calreticulin and virus G-protein coupled receptor induced the antitumor immune response in Balb/C mice. Cancer Biol Ther (2011) 1.43
Neural stem cell-based cell carriers enhance therapeutic efficacy of an oncolytic adenovirus in an orthotopic mouse model of human glioblastoma. Mol Ther (2011) 1.39
Apical targeting of syntaxin 3 is essential for epithelial cell polarity. J Cell Biol (2006) 1.32
Down-regulation of miR-27a might reverse multidrug resistance of esophageal squamous cell carcinoma. Dig Dis Sci (2009) 1.30
Low-dose radiation enhances survivin-mediated virotherapy against malignant glioma stem cells. Cancer Res (2008) 1.30
The prognostic and chemotherapeutic value of miR-296 in esophageal squamous cell carcinoma. Ann Surg (2010) 1.28
A comparative study of neural and mesenchymal stem cell-based carriers for oncolytic adenovirus in a model of malignant glioma. Mol Pharm (2011) 1.27
Stimulation of TLR9 with CpG ODN enhances apoptosis of glioma and prolongs the survival of mice with experimental brain tumors. Glia (2006) 1.26
Generation of mice harboring a Sox4 conditional null allele. Genesis (2007) 1.25
Sequential requirement of Sox4 and Sox11 during development of the sympathetic nervous system. Development (2010) 1.22
A preclinical evaluation of neural stem cell-based cell carrier for targeted antiglioma oncolytic virotherapy. J Natl Cancer Inst (2013) 1.21
Fiber-knob modifications enhance adenoviral tropism and gene transfer in malignant glioma. J Gene Med (2007) 1.15
Generating rate equations for complex enzyme systems by a computer-assisted systematic method. BMC Bioinformatics (2009) 1.12
Repression of tyrosine hydroxylase is responsible for the sex-linked chocolate mutation of the silkworm, Bombyx mori. Proc Natl Acad Sci U S A (2010) 1.10
The presence of IL-17A and T helper 17 cells in experimental mouse brain tumors and human glioma. PLoS One (2010) 1.09
Mesenchymal stem cells modified with a single-chain antibody against EGFRvIII successfully inhibit the growth of human xenograft malignant glioma. PLoS One (2010) 1.08
Synovial joint morphogenesis requires the chondrogenic action of Sox5 and Sox6 in growth plate and articular cartilage. Dev Biol (2010) 1.08
High expression of miR-210 predicts poor survival in patients with breast cancer: a meta-analysis. Gene (2012) 1.08
Sub-10 nm Fe3O4@Cu(2-x)S core-shell nanoparticles for dual-modal imaging and photothermal therapy. J Am Chem Soc (2013) 1.08
MicroRNA-21: a therapeutic target for reversing drug resistance in cancer. Expert Opin Ther Targets (2013) 1.07
CD46 represents a target for adenoviral gene therapy of malignant glioma. Hum Gene Ther (2006) 1.07
The role of late/slow replication of the FRA16D in common fragile site induction. Genes Chromosomes Cancer (2004) 1.05
Bone marrow mesenchymal stem cells loaded with an oncolytic adenovirus suppress the anti-adenoviral immune response in the cotton rat model. Mol Ther (2010) 1.02
Oncolytic adenoviral vectors which employ the survivin promoter induce glioma oncolysis via a process of beclin-dependent autophagy. Int J Oncol (2009) 1.02
Fibrin-binding, peptide amphiphile micelles for targeting glioblastoma. Biomaterials (2013) 1.00
Enhanced binding affinity, remarkable selectivity, and high capacity of CO2 by dual functionalization of a rht-type metal-organic framework. Angew Chem Int Ed Engl (2011) 0.98
Novel recombinant adenoviral vector that targets the interleukin-13 receptor alpha2 chain permits effective gene transfer to malignant glioma. Hum Gene Ther (2007) 0.98
MicroRNA-212 inhibits proliferation of gastric cancer by directly repressing retinoblastoma binding protein 2. J Cell Biochem (2013) 0.98
Extracellular vesicle-mediated transfer of donor genomic DNA to recipient cells is a novel mechanism for genetic influence between cells. J Mol Cell Biol (2013) 0.98
Nanoparticle-programmed self-destructive neural stem cells for glioblastoma targeting and therapy. Small (2013) 0.97
Therapeutic effect of neural stem cells expressing TRAIL and bortezomib in mice with glioma xenografts. Cancer Lett (2011) 0.97
Mitoxantrone-mediated apoptotic B16-F1 cells induce specific anti-tumor immune response. Cell Mol Immunol (2009) 0.96
Inhibitory effect of D1-like and D3 dopamine receptors on norepinephrine-induced proliferation in vascular smooth muscle cells. Am J Physiol Heart Circ Physiol (2008) 0.95
Role of GRK4 in the regulation of arterial AT1 receptor in hypertension. Hypertension (2013) 0.95
Sucrose functions as a signal involved in the regulation of strawberry fruit development and ripening. New Phytol (2013) 0.94
HHV-8 seroprevalence in blood donors and HIV-positive individuals in Shandong area, China. J Infect (2006) 0.94
Angiotensin II AT(2) receptor decreases AT(1) receptor expression and function via nitric oxide/cGMP/Sp1 in renal proximal tubule cells from Wistar-Kyoto rats. J Hypertens (2012) 0.93
EGFR mutations and HER2/3 protein expression and clinical outcome in Chinese advanced non-small cell lung cancer patients treated with gefitinib. J Cancer Res Clin Oncol (2008) 0.93
Targeting adenovirus to CD80 and CD86 receptors increases gene transfer efficiency to malignant glioma cells. J Neurosurg (2007) 0.92
Enhanced transduction of malignant glioma with a double targeted Ad5/3-RGD fiber-modified adenovirus. Mol Cancer Ther (2006) 0.92
Palmitoylation of the Autographa californica multicapsid nucleopolyhedrovirus envelope glycoprotein GP64: mapping, functional studies, and lipid rafts. J Virol (2003) 0.92
Telomere dynamics in mice and humans. Semin Hematol (2013) 0.92
The timing of neural stem cell-based virotherapy is critical for optimal therapeutic efficacy when applied with radiation and chemotherapy for the treatment of glioblastoma. Stem Cells Transl Med (2013) 0.91
PDGF-D contributes to neointimal hyperplasia in rat model of vessel injury. Biochem Biophys Res Commun (2005) 0.91
EGCG attenuates high glucose-induced endothelial cell inflammation by suppression of PKC and NF-κB signaling in human umbilical vein endothelial cells. Life Sci (2013) 0.91
Oncolytic adenoviral therapy for glioblastoma multiforme. Neurosurg Focus (2006) 0.90
A general synthesis for PEDOT-coated nonconductive materials and PEDOT hollow particles by aqueous chemical polymerization. Small (2008) 0.90
NELIN, a new F-actin associated protein, stimulates HeLa cell migration and adhesion. Biochem Biophys Res Commun (2005) 0.90
Field evaluation of effects of transgenic cry1Ab/cry1Ac, cry1C and cry2A rice on Cnaphalocrocis medinalis and its arthropod predators. Sci China Life Sci (2011) 0.90
Specific targeting of the vasculature of gastric cancer by a new tumor-homing peptide CGNSNPKSC. J Control Release (2008) 0.89
Mesenchymal stem cells promote cardiomyocyte hypertrophy in vitro through hypoxia-induced paracrine mechanisms. Clin Exp Pharmacol Physiol (2008) 0.89
The expression of BST2 in human and experimental mouse brain tumors. Exp Mol Pathol (2011) 0.88
Short hairpin RNA-mediated fibronectin knockdown delays tumor growth in a mouse glioma model. Neoplasia (2010) 0.88
Site-specific growth of Au-Pd alloy horns on Au nanorods: a platform for highly sensitive monitoring of catalytic reactions by surface enhancement Raman spectroscopy. J Am Chem Soc (2013) 0.88
Zinc ribbon domain-containing 1 (ZNRD1) mediates multidrug resistance of leukemia cells through regulation of P-glycoprotein and Bcl-2. Mol Cancer Ther (2005) 0.88
The role of epidermal growth factor receptor in prognosis and treatment of gastric cancer. Expert Rev Gastroenterol Hepatol (2013) 0.88
Characterization and immunotherapeutic implications for a novel antibody targeting interleukin (IL)-13 receptor α2. J Biol Chem (2012) 0.88
Self-powered water splitting using flowing kinetic energy. Adv Mater (2014) 0.88
Baicalin improved the spatial learning ability of global ischemia/reperfusion rats by reducing hippocampal apoptosis. Brain Res (2012) 0.87
Comparative study of the effects of recombinant human epidermal growth factor and basic fibroblast growth factor on corneal epithelial wound healing and neovascularization in vivo and in vitro. Ophthalmic Res (2012) 0.87
miR-210: a therapeutic target in cancer. Expert Opin Ther Targets (2012) 0.87
D3 dopamine receptor regulation of ETB receptors in renal proximal tubule cells from WKY and SHRs. Am J Hypertens (2009) 0.87
HuD regulates the cpg15 expression via the 3'-UTR and AU-rich element. Neurochem Res (2011) 0.87
Tra2betal regulates P19 neuronal differentiation and the splicing of FGF-2R and GluR-B minigenes. Cell Biol Int (2004) 0.86
Multifunctional ferritin cage nanostructures for fluorescence and MR imaging of tumor cells. Nanoscale (2011) 0.86
A safety and efficacy study of local delivery of interleukin-12 transgene by PPC polymer in a model of experimental glioma. Anticancer Drugs (2008) 0.86
Generation of mice harboring a Sox5 conditional null allele. Genesis (2008) 0.86
Highly mesoporous single-crystalline zeolite beta synthesized using a nonsurfactant cationic polymer as a dual-function template. J Am Chem Soc (2014) 0.86
Specific receptor subtype mediation of LPA-induced dual effects in cardiac fibroblasts. FEBS Lett (2006) 0.85
Protective effects of aliskiren on ischemia-reperfusion-induced renal injury in rats. Eur J Pharmacol (2013) 0.85
Complications and clinical analysis of 416 consecutive cochlear implantations. Int J Pediatr Otorhinolaryngol (2011) 0.85
Lanthanide-doped Na(x)ScF(3+x) nanocrystals: crystal structure evolution and multicolor tuning. J Am Chem Soc (2012) 0.85
Mechanistic investigation into the spontaneous linear assembly of gold nanospheres. Phys Chem Chem Phys (2010) 0.85
Fibroblast growth factor receptor 2: a therapeutic target in gastric cancer. Expert Rev Gastroenterol Hepatol (2013) 0.85
Angiogenesis-related microRNAs in colon cancer. Expert Opin Biol Ther (2012) 0.84
Monolayer MoSe2 grown by chemical vapor deposition for fast photodetection. ACS Nano (2014) 0.84
Drug resistance-related miRNAs in hepatocellular cancer. Expert Rev Gastroenterol Hepatol (2014) 0.84
Reversal of multidrug resistance of vincristine-resistant gastric adenocarcinoma cells through up-regulation of DARPP-32. Cell Biol Int (2007) 0.84
Specific LPA receptor subtype mediation of LPA-induced hypertrophy of cardiac myocytes and involvement of Akt and NFkappaB signal pathways. J Cell Biochem (2008) 0.84