Published in J Biol Chem on March 03, 2009
DNA interstrand crosslink repair in mammalian cells: step by step. Crit Rev Biochem Mol Biol (2010) 1.82
Recent advances in the structural mechanisms of DNA glycosylases. Biochim Biophys Acta (2012) 1.30
Pathways for repairing and tolerating the spectrum of oxidative DNA lesions. Cancer Lett (2012) 1.20
Evidence for the involvement of DNA repair enzyme NEIL1 in nucleotide excision repair of (5'R)- and (5'S)-8,5'-cyclo-2'-deoxyadenosines. Biochemistry (2010) 1.05
Repair of DNA interstrand cross-links during S phase of the mammalian cell cycle. Environ Mol Mutagen (2010) 0.99
Repair of hydantoin lesions and their amine adducts in DNA by base and nucleotide excision repair. J Am Chem Soc (2013) 0.87
Replication-fork stalling and processing at a single psoralen interstrand crosslink in Xenopus egg extracts. PLoS One (2011) 0.87
DNA repair pathways in human multiple myeloma: role in oncogenesis and potential targets for treatment. Cell Cycle (2013) 0.86
A novel link to base excision repair? Trends Biochem Sci (2010) 0.86
Replication-Dependent Unhooking of DNA Interstrand Cross-Links by the NEIL3 Glycosylase. Cell (2016) 0.85
Substrate specific stimulation of NEIL1 by WRN but not the other human RecQ helicases. DNA Repair (Amst) (2010) 0.84
NEIL1 responds and binds to psoralen-induced DNA interstrand crosslinks. J Biol Chem (2013) 0.83
Evidence for base excision repair processing of DNA interstrand crosslinks. Mutat Res (2012) 0.80
A quantitative mass spectrometry-based approach for assessing the repair of 8-methoxypsoralen-induced DNA interstrand cross-links and monoadducts in mammalian cells. Anal Chem (2013) 0.80
Cloning and characterization of a wheat homologue of apurinic/apyrimidinic endonuclease Ape1L. PLoS One (2014) 0.79
An inverse switch in DNA base excision and strand break repair contributes to melphalan resistance in multiple myeloma cells. PLoS One (2013) 0.79
Functional DNA repair signature of cancer cell lines exposed to a set of cytotoxic anticancer drugs using a multiplexed enzymatic repair assay on biochip. PLoS One (2012) 0.77
Structure of a DNA glycosylase that unhooks interstrand cross-links. Proc Natl Acad Sci U S A (2017) 0.75
A role for the base excision repair enzyme NEIL3 in replication-dependent repair of interstrand DNA cross-links derived from psoralen and abasic sites. DNA Repair (Amst) (2017) 0.75
Psoralens as photoactive probes of nucleic acid structure and function: organic chemistry, photochemistry, and biochemistry. Annu Rev Biochem (1985) 4.83
Mechanism of replication-coupled DNA interstrand crosslink repair. Cell (2008) 4.53
The structure-specific endonuclease Ercc1-Xpf is required to resolve DNA interstrand cross-link-induced double-strand breaks. Mol Cell Biol (2004) 3.94
Repair of DNA interstrand cross-links. Mutat Res (2001) 3.92
Defining the roles of nucleotide excision repair and recombination in the repair of DNA interstrand cross-links in mammalian cells. Mol Cell Biol (2000) 3.57
Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA. Proc Natl Acad Sci U S A (2002) 3.33
Repair of DNA interstrand crosslinks: molecular mechanisms and clinical relevance. Lancet Oncol (2001) 2.98
The structure-specific endonuclease Mus81-Eme1 promotes conversion of interstrand DNA crosslinks into double-strands breaks. EMBO J (2006) 2.89
Repair of an interstrand DNA cross-link initiated by ERCC1-XPF repair/recombination nuclease. J Biol Chem (2000) 2.60
A novel human DNA glycosylase that removes oxidative DNA damage and is homologous to Escherichia coli endonuclease VIII. DNA Repair (Amst) (2002) 2.41
Atomic model of a pyrimidine dimer excision repair enzyme complexed with a DNA substrate: structural basis for damaged DNA recognition. Cell (1995) 2.36
The intricate structural chemistry of base excision repair machinery: implications for DNA damage recognition, removal, and repair. DNA Repair (Amst) (2007) 2.26
The metabolic syndrome resulting from a knockout of the NEIL1 DNA glycosylase. Proc Natl Acad Sci U S A (2006) 2.17
Multiple repair pathways mediate tolerance to chemotherapeutic cross-linking agents in vertebrate cells. Cancer Res (2005) 2.05
Defective DNA cross-link removal in Chinese hamster cell mutants hypersensitive to bifunctional alkylating agents. Cancer Res (1985) 2.02
Structural analysis of an Escherichia coli endonuclease VIII covalent reaction intermediate. EMBO J (2002) 1.87
Involvement of nucleotide excision repair in a recombination-independent and error-prone pathway of DNA interstrand cross-link repair. Mol Cell Biol (2001) 1.76
In vitro repair of psoralen-DNA cross-links by RecA, UvrABC, and the 5'-exonuclease of DNA polymerase I. J Biol Chem (1989) 1.74
Role for DNA polymerase kappa in the processing of N2-N2-guanine interstrand cross-links. J Biol Chem (2008) 1.64
Interaction of the human DNA glycosylase NEIL1 with proliferating cell nuclear antigen. The potential for replication-associated repair of oxidized bases in mammalian genomes. J Biol Chem (2007) 1.63
REV3 and REV1 play major roles in recombination-independent repair of DNA interstrand cross-links mediated by monoubiquitinated proliferating cell nuclear antigen (PCNA). J Biol Chem (2006) 1.61
DNA repair by eukaryotic nucleotide excision nuclease. Removal of thymine dimer and psoralen monoadduct by HeLa cell-free extract and of thymine dimer by Xenopus laevis oocytes. J Biol Chem (1993) 1.57
Use of psoralen-modified oligonucleotides to trap three-stranded RecA-DNA complexes and repair of these cross-linked complexes by ABC excinuclease. J Biol Chem (1988) 1.55
Psoralen monoadducts and interstrand cross-links in DNA. Biochim Biophys Acta (1971) 1.52
The crystal structure of human endonuclease VIII-like 1 (NEIL1) reveals a zincless finger motif required for glycosylase activity. Proc Natl Acad Sci U S A (2004) 1.52
Construction of DNA substrates modified with psoralen at a unique site and study of the action mechanism of ABC excinuclease on these uniformly modified substrates. J Biol Chem (1986) 1.38
Inactivating mutations of the human base excision repair gene NEIL1 in gastric cancer. Carcinogenesis (2004) 1.30
Processing of a psoralen DNA interstrand cross-link by XPF-ERCC1 complex in vitro. J Biol Chem (2007) 1.29
Physical and functional interaction between human oxidized base-specific DNA glycosylase NEIL1 and flap endonuclease 1. J Biol Chem (2008) 1.27
RecA-dependent incision of psoralen-crosslinked DNA by (A)BC excinuclease. Nucleic Acids Res (1991) 1.22
NEIL1 excises 3' end proximal oxidative DNA lesions resistant to cleavage by NTH1 and OGG1. Nucleic Acids Res (2005) 1.20
The role of BRCA2 in replication-coupled DNA interstrand cross-link repair in vitro. Nat Struct Mol Biol (2006) 1.06
Excision of the imidazole ring-opened form of N-2-aminofluorene-C(8)-guanine adduct in poly(dG-dC) by Escherichia coli formamidopyrimidine-DNA glycosylase. Carcinogenesis (1989) 1.06
Psoralen-induced DNA adducts are substrates for the base excision repair pathway in human cells. Nucleic Acids Res (2007) 1.02
DNA structural reorganization upon conversion of a psoralen furan-side monoadduct to an interstrand cross-link: implications for DNA repair. Proc Natl Acad Sci U S A (1995) 1.02
The crystal structures of psoralen cross-linked DNAs: drug-dependent formation of Holliday junctions. J Mol Biol (2001) 0.96
Lesion specificity in the base excision repair enzyme hNeil1: modeling and dynamics studies. Biochemistry (2007) 0.94
Bacterial base excision repair enzyme Fpg recognizes bulky N7-substituted-FapydG lesion via unproductive binding mode. Chem Biol (2008) 0.90
Repair of O6-G-alkyl-O6-G interstrand cross-links by human O6-alkylguanine-DNA alkyltransferase. Biochemistry (2008) 0.90
NEIL1 is the major DNA glycosylase that processes 5-hydroxyuracil in the proximity of a DNA single-strand break. Biochemistry (2007) 0.88
The solution structure of a psoralen cross-linked DNA duplex by NMR and relaxation matrix refinement. Biochem Biophys Res Commun (1996) 0.88
8-Methoxypsoralen-nucleic acid photoreaction. Effect of methyl substitution on pyrone vs. furan photoaddition. J Med Chem (1984) 0.85
Low-level psoralen--deoxyribonucleic acid cross-links induced by single laser pulses. Biochemistry (1981) 0.81
Structure of the DNA interstrand cross-link of 4,5',8-trimethylpsoralen. Biochemistry (1992) 0.80
The FANC pathway and BLM collaborate during mitosis to prevent micro-nucleation and chromosome abnormalities. Nat Cell Biol (2009) 2.62
The DNA crosslink-induced S-phase checkpoint depends on ATR-CHK1 and ATR-NBS1-FANCD2 pathways. EMBO J (2004) 2.20
Nonapoptotic role for Apaf-1 in the DNA damage checkpoint. Mol Cell (2007) 2.20
ERCC1 and MUS81-EME1 promote sister chromatid separation by processing late replication intermediates at common fragile sites during mitosis. Nat Cell Biol (2013) 1.49
BLM and the FANC proteins collaborate in a common pathway in response to stalled replication forks. EMBO J (2004) 1.48
Alternative nucleotide incision repair pathway for oxidative DNA damage. Nature (2002) 1.46
The major human AP endonuclease (Ape1) is involved in the nucleotide incision repair pathway. Nucleic Acids Res (2004) 1.42
Werner's syndrome protein is phosphorylated in an ATR/ATM-dependent manner following replication arrest and DNA damage induced during the S phase of the cell cycle. Oncogene (2003) 1.34
DNA synthesis by Pol η promotes fragile site stability by preventing under-replicated DNA in mitosis. J Cell Biol (2013) 1.30
Enzymology of the repair of free radicals-induced DNA damage. Oncogene (2002) 1.29
Loss of CHK1 function impedes DNA damage-induced FANCD2 monoubiquitination but normalizes the abnormal G2 arrest in Fanconi anemia. Hum Mol Genet (2007) 1.17
DNA cross-link-dependent RAD50/MRE11/NBS1 subnuclear assembly requires the Fanconi anemia C protein. Hum Mol Genet (2002) 1.16
Uncoupling of the base excision and nucleotide incision repair pathways reveals their respective biological roles. Proc Natl Acad Sci U S A (2006) 1.10
Real-time studies of conformational dynamics of the repair enzyme E. coli formamidopyrimidine-DNA glycosylase and its DNA complexes during catalytic cycle. Mutat Res (2009) 1.09
Aberrant activation of stress-response pathways leads to TNF-alpha oversecretion in Fanconi anemia. Blood (2007) 1.09
A molecular beacon assay for measuring base excision repair activities. Biochem Biophys Res Commun (2004) 1.06
3R coordination by Fanconi anemia proteins. Biochimie (2005) 1.04
The FANC pathway and mitosis: a replication legacy. Cell Cycle (2009) 1.03
Psoralen-induced DNA adducts are substrates for the base excision repair pathway in human cells. Nucleic Acids Res (2007) 1.02
Fanconi anemia proteins and the s phase checkpoint. Cell Cycle (2004) 1.02
Hijacking of the human alkyl-N-purine-DNA glycosylase by 3,N4-ethenocytosine, a lipid peroxidation-induced DNA adduct. J Biol Chem (2004) 0.98
Critical involvement of the ATM-dependent DNA damage response in the apoptotic demise of HIV-1-elicited syncytia. PLoS One (2008) 0.95
Hypoxia-dependent inhibition of tumor cell susceptibility to CTL-mediated lysis involves NANOG induction in target cells. J Immunol (2011) 0.90
Presence of a defect in karyokinesis during megakaryocyte endomitosis. Cell Cycle (2012) 0.89
USP1 deubiquitinase maintains phosphorylated CHK1 by limiting its DDB1-dependent degradation. Hum Mol Genet (2011) 0.89
Role of the ceramide-signaling pathways in ionizing radiation-induced apoptosis. Oncogene (2003) 0.88
FANC pathway promotes UV-induced stalled replication forks recovery by acting both upstream and downstream Polη and Rev1. PLoS One (2013) 0.87
Coupling of the nucleotide incision and 3'-->5' exonuclease activities in Escherichia coli endonuclease IV: Structural and genetic evidences. Mutat Res (2009) 0.85
Role of mismatch-specific uracil-DNA glycosylase in repair of 3,N4-ethenocytosine in vivo. DNA Repair (Amst) (2004) 0.84
The Fanconi anemia pathway promotes DNA glycosylase-dependent excision of interstrand DNA crosslinks. Environ Mol Mutagen (2010) 0.84
Step-by-step mechanism of DNA damage recognition by human 8-oxoguanine DNA glycosylase. Biochim Biophys Acta (2013) 0.84
Insight into mechanisms of 3'-5' exonuclease activity and removal of bulky 8,5'-cyclopurine adducts by apurinic/apyrimidinic endonucleases. Proc Natl Acad Sci U S A (2013) 0.82
Excision of 8-oxoguanine from methylated CpG dinucleotides by human 8-oxoguanine DNA glycosylase. FEBS Lett (2013) 0.81
Uracil in duplex DNA is a substrate for the nucleotide incision repair pathway in human cells. Proc Natl Acad Sci U S A (2013) 0.81
Fanconi anemia C gene product regulates expression of genes involved in differentiation and inflammation. Oncogene (2004) 0.81
The FANC pathway is activated by adenovirus infection and promotes viral replication-dependent recombination. Nucleic Acids Res (2011) 0.81
Functional characterization of the Caenorhabditis elegans DNA repair enzyme APN-1. DNA Repair (Amst) (2012) 0.80
African swine fever virus AP endonuclease is a redox-sensitive enzyme that repairs alkylating and oxidative damage to DNA. Virology (2009) 0.79
Impact of pyrophosphate and O-ethyl-substituted pyrophosphate groups on DNA structure. J Phys Chem B (2007) 0.78
Presence of base excision repair enzymes in the wheat aleurone and their activation in cells undergoing programmed cell death. Plant Physiol Biochem (2011) 0.78
hSMG-1 is a granzyme B-associated stress-responsive protein kinase. J Mol Med (Berl) (2011) 0.78
Two sequential phosphates 3' adjacent to the 8-oxoguanosine are crucial for lesion excision by E. coli Fpg protein and human 8-oxoguanine-DNA glycosylase. Biochimie (2005) 0.78
Lys98 substitution in human AP endonuclease 1 affects the kinetic mechanism of enzyme action in base excision and nucleotide incision repair pathways. PLoS One (2011) 0.75