A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein.

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Published in Mol Cell Proteomics on September 08, 2008

Authors

Marilyn Goudreault1, Lisa M D'Ambrosio, Michelle J Kean, Michael J Mullin, Brett G Larsen, Amy Sanchez, Sidharth Chaudhry, Ginny I Chen, Frank Sicheri, Alexey I Nesvizhskii, Ruedi Aebersold, Brian Raught, Anne-Claude Gingras

Author Affiliations

1: Samuel Lunenfeld Research Institute at Mount Sinai Hospital, Toronto, Ontario M5G 1X5, Canada.

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The Functional Genomics Experiment model (FuGE): an extensible framework for standards in functional genomics. Nat Biotechnol (2007) 3.55

Options and considerations when selecting a quantitative proteomics strategy. Nat Biotechnol (2010) 3.51

SAINT: probabilistic scoring of affinity purification-mass spectrometry data. Nat Methods (2010) 3.50

Reporting protein identification data: the next generation of guidelines. Mol Cell Proteomics (2006) 3.50

Reproducible isolation of distinct, overlapping segments of the phosphoproteome. Nat Methods (2007) 3.46

Probing native protein structures by chemical cross-linking, mass spectrometry, and bioinformatics. Mol Cell Proteomics (2010) 3.44

Rapid and systematic analysis of the RNA recognition specificities of RNA-binding proteins. Nat Biotechnol (2009) 3.44

Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach. Proc Natl Acad Sci U S A (2012) 3.42

Mechanistic link between PKR dimerization, autophosphorylation, and eIF2alpha substrate recognition. Cell (2005) 3.38

A high-confidence human plasma proteome reference set with estimated concentrations in PeptideAtlas. Mol Cell Proteomics (2011) 3.37

An assessment of software solutions for the analysis of mass spectrometry based quantitative proteomics data. J Proteome Res (2008) 3.36

A high-quality catalog of the Drosophila melanogaster proteome. Nat Biotechnol (2007) 3.34

Automated statistical analysis of protein abundance ratios from data generated by stable-isotope dilution and tandem mass spectrometry. Anal Chem (2003) 3.33

Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis. Genes Dev (2009) 3.31

Targeted quantitative analysis of Streptococcus pyogenes virulence factors by multiple reaction monitoring. Mol Cell Proteomics (2008) 3.29

Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases. EMBO J (2004) 3.29

Orm family proteins mediate sphingolipid homeostasis. Nature (2010) 3.29

Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells. Cell (2012) 3.26

A database of mass spectrometric assays for the yeast proteome. Nat Methods (2008) 3.19

PASSEL: the PeptideAtlas SRMexperiment library. Proteomics (2012) 3.14

Significance analysis of spectral count data in label-free shotgun proteomics. Mol Cell Proteomics (2008) 3.12

mProphet: automated data processing and statistical validation for large-scale SRM experiments. Nat Methods (2011) 3.10

Comparative functional analysis of the Caenorhabditis elegans and Drosophila melanogaster proteomes. PLoS Biol (2009) 3.09

ProbID: a probabilistic algorithm to identify peptides through sequence database searching using tandem mass spectral data. Proteomics (2002) 3.01

HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity. Curr Biol (2009) 2.98

Protein identification false discovery rates for very large proteomics data sets generated by tandem mass spectrometry. Mol Cell Proteomics (2009) 2.96

An integrated workflow for charting the human interaction proteome: insights into the PP2A system. Mol Syst Biol (2009) 2.92

Mass spectrometry in high-throughput proteomics: ready for the big time. Nat Methods (2010) 2.91

iProphet: multi-level integrative analysis of shotgun proteomic data improves peptide and protein identification rates and error estimates. Mol Cell Proteomics (2011) 2.88

Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry. Nat Methods (2005) 2.87

Analysis, statistical validation and dissemination of large-scale proteomics datasets generated by tandem MS. Drug Discov Today (2004) 2.82