Published in Anesthesiology on October 01, 2008
Liars, damn liars, and propensity scores. Anesthesiology (2008) 3.17
Incidence, risk factors and consequences of ICU delirium. Intensive Care Med (2006) 4.82
Hypocapnia. N Engl J Med (2002) 2.67
Atelectasis causes alveolar injury in nonatelectatic lung regions. Am J Respir Crit Care Med (2006) 2.56
The systemic inflammatory response to cardiac surgery: implications for the anesthesiologist. Anesthesiology (2002) 2.55
Hypocapnia and the injured brain: more harm than benefit. Crit Care Med (2010) 2.35
Carbon dioxide attenuates pulmonary impairment resulting from hyperventilation. Crit Care Med (2003) 2.31
Hypercapnic acidosis attenuates endotoxin-induced acute lung injury. Am J Respir Crit Care Med (2003) 2.31
Lung-protective ventilation in the operating room: time to implement? Anesthesiology (2014) 2.15
Protocolized intensive care unit management of analgesia, sedation, and delirium improves analgesia and subsyndromal delirium rates. Anesth Analg (2010) 2.09
Phase I study of RO4929097, a gamma secretase inhibitor of Notch signaling, in patients with refractory metastatic or locally advanced solid tumors. J Clin Oncol (2012) 2.04
Early changes in lung gene expression due to high tidal volume. Am J Respir Crit Care Med (2003) 2.03
Negative-pressure ventilation: better oxygenation and less lung injury. Am J Respir Crit Care Med (2007) 1.71
Anesthetic technique and the cytokine and matrix metalloproteinase response to primary breast cancer surgery. Reg Anesth Pain Med (2010) 1.67
Lung development and susceptibility to ventilator-induced lung injury. Am J Respir Crit Care Med (2005) 1.62
Preclinical profile of a potent gamma-secretase inhibitor targeting notch signaling with in vivo efficacy and pharmacodynamic properties. Cancer Res (2009) 1.58
Pulmonary atelectasis: a pathogenic perioperative entity. Anesthesiology (2005) 1.57
SKIP3, a novel Drosophila tribbles ortholog, is overexpressed in human tumors and is regulated by hypoxia. Oncogene (2003) 1.52
Airway pressure release ventilation improves pulmonary blood flow in infants after cardiac surgery. Crit Care Med (2011) 1.52
Nek8, a NIMA family kinase member, is overexpressed in primary human breast tumors. Gene (2004) 1.52
Glucose in the ICU--evidence, guidelines, and outcomes. N Engl J Med (2012) 1.52
Emergency airway management: competence versus expertise? Anesthesiology (2008) 1.49
Imaging the interaction of atelectasis and overdistension in surfactant-depleted lungs. Crit Care Med (2013) 1.48
Dissociation of inflammatory mediators and function: experimental lung injury in nonpulmonary sepsis. Crit Care Med (2013) 1.48
Continuous negative abdominal distension augments recruitment of atelectatic lung. Crit Care Med (2012) 1.46
Mechanical ventilation induces neutrophil extracellular trap formation. Anesthesiology (2015) 1.44
Identification of the MEK1(F129L) activating mutation as a potential mechanism of acquired resistance to MEK inhibition in human cancers carrying the B-RafV600E mutation. Cancer Res (2011) 1.40
Airway management in the lateral position: a randomized controlled trial. Anesth Analg (2005) 1.37
Bench-to-bedside review: carbon dioxide. Crit Care (2010) 1.29
Atelectasis causes vascular leak and lethal right ventricular failure in uninjured rat lungs. Am J Respir Crit Care Med (2003) 1.20
Have changes in ventilation practice improved outcome in children with acute lung injury? Pediatr Crit Care Med (2007) 1.20
Oxygenation response to positive end-expiratory pressure predicts mortality in acute respiratory distress syndrome. A secondary analysis of the LOVS and ExPress trials. Am J Respir Crit Care Med (2014) 1.11
Therapeutic hypercapnia prevents chronic hypoxia-induced pulmonary hypertension in the newborn rat. Am J Physiol Lung Cell Mol Physiol (2006) 1.11
Permissive hypercapnia--role in protective lung ventilatory strategies. Intensive Care Med (2004) 1.10
BRAFV600E negatively regulates the AKT pathway in melanoma cell lines. PLoS One (2012) 1.08
Acute vasodilator effects of Rho-kinase inhibitors in neonatal rats with pulmonary hypertension unresponsive to nitric oxide. Am J Physiol Lung Cell Mol Physiol (2007) 1.06
Decrease in bispectral index preceding intraoperative hemodynamic crisis: evidence of acute alteration of propofol pharmacokinetics. Anesthesiology (2002) 1.05
High tidal volume ventilation causes different inflammatory responses in newborn versus adult lung. Am J Respir Crit Care Med (2004) 1.04
Effects of ventilation strategy on distribution of lung inflammatory cell activity. Crit Care (2013) 1.03
Lung-derived soluble mediators are pathogenic in ventilator-induced lung injury. Am J Physiol Lung Cell Mol Physiol (2011) 1.03
High tumor levels of IL6 and IL8 abrogate preclinical efficacy of the γ-secretase inhibitor, RO4929097. Mol Oncol (2011) 1.02
Spontaneous effort causes occult pendelluft during mechanical ventilation. Am J Respir Crit Care Med (2013) 1.02
Effects of therapeutic hypercapnia on mesenteric ischemia-reperfusion injury. Am J Respir Crit Care Med (2003) 0.99
Registration and design alterations of clinical trials in critical care: a cross-sectional observational study. Intensive Care Med (2014) 0.99
Continuous positive airway pressure causes lung injury in a model of sepsis. Am J Physiol Lung Cell Mol Physiol (2005) 0.98
An official multi-society statement: the role of clinical research results in the practice of critical care medicine. Am J Respir Crit Care Med (2012) 0.97
Atelectasis in the perioperative patient. Curr Opin Anaesthesiol (2007) 0.96
Identification of novel, potent and selective inhibitors of Polo-like kinase 1. Bioorg Med Chem Lett (2011) 0.96
Early growth response-1 worsens ventilator-induced lung injury by up-regulating prostanoid synthesis. Am J Respir Crit Care Med (2010) 0.95
Measuring diaphragm thickness with ultrasound in mechanically ventilated patients: feasibility, reproducibility and validity. Intensive Care Med (2015) 0.95
Early growth response factor-1 in acute lung injury. Am J Physiol Lung Cell Mol Physiol (2007) 0.95
The novel gamma secretase inhibitor RO4929097 reduces the tumor initiating potential of melanoma. PLoS One (2011) 0.94
CrossTalk proposal: there is added benefit to providing permissive hypercapnia in the treatment of ARDS. J Physiol (2013) 0.93
Hypercapnic acidosis does not modulate the severity of bacterial pneumonia-induced lung injury. Crit Care Med (2005) 0.93
Hypercapnic acidosis in ventilator-induced lung injury. Intensive Care Med (2010) 0.92
Therapeutic hypercapnia is not protective in the in vivo surfactant-depleted rabbit lung. Pediatr Res (2003) 0.91
Oxygen attenuates atelectasis-induced injury in the in vivo rat lung. Anesthesiology (2005) 0.89
Inactivation of mirk/dyrk1b kinase targets quiescent pancreatic cancer cells. Mol Cancer Ther (2011) 0.88
Therapeutic effects of hypercapnia on chronic lung injury and vascular remodeling in neonatal rats. Am J Physiol Lung Cell Mol Physiol (2009) 0.88
Epinephrine increases mortality after brief asphyxial cardiac arrest in an in vivo rat model. Anesth Analg (2006) 0.87
Hypercapnia increases cerebral tissue oxygen tension in anesthetized rats. Can J Anaesth (2003) 0.86
Do soluble mediators cause ventilator-induced lung injury and multi-organ failure? Intensive Care Med (2010) 0.86
Prolonged mechanical ventilation induces cell cycle arrest in newborn rat lung. PLoS One (2011) 0.85
Inhibition of the NOTCH pathway using γ-secretase inhibitor RO4929097 has limited antitumor activity in established glial tumors. Anticancer Drugs (2015) 0.85
Relative effects of negative versus positive pressure ventilation depend on applied conditions. Intensive Care Med (2012) 0.84
Rescue treatment with a Rho-kinase inhibitor normalizes right ventricular function and reverses remodeling in juvenile rats with chronic pulmonary hypertension. Am J Physiol Heart Circ Physiol (2010) 0.84
Mechanical ventilation-induced apoptosis in newborn rat lung is mediated via FasL/Fas pathway. Am J Physiol Lung Cell Mol Physiol (2013) 0.84
Hydrogen sulfide in lung injury: therapeutic hope from a toxic gas? Anesthesiology (2010) 0.83
The effect of global hypoxia on myocardial function after successful cardiopulmonary resuscitation in a laboratory model. Resuscitation (2005) 0.82
Scoring systems for the critically ill: use, misuse and abuse. Can J Anaesth (2006) 0.82
Positive clinical trials: understand the control group before implementing the result. Am J Respir Crit Care Med (2004) 0.82
12-hour versus 24-hour creatinine clearance in critically ill pediatric patients. Pediatr Res (2005) 0.82
Fatal fibrinolysis during orthotopic liver transplantation in patients receiving solvent/detergent-treated plasma (Octaplas). J Cardiothorac Vasc Anesth (2006) 0.81
Perioperative modifications of respiratory function. Best Pract Res Clin Anaesthesiol (2010) 0.81
Use of dynamic CT in acute respiratory distress syndrome (ARDS) with comparison of positive and negative pressure ventilation. Eur Radiol (2008) 0.81
Hypercapnia: clinical relevance and mechanisms of action. Curr Opin Crit Care (2015) 0.81
Transthoracic echocardiography does not improve prediction of outcome over APACHE II in medical-surgical intensive care. Can J Anaesth (2003) 0.80
Therapeutic hypercapnia: careful science, better trials. Am J Respir Crit Care Med (2005) 0.80
Cyclooxygenase inhibition in ventilator-induced lung injury. Anesth Analg (2010) 0.80
Positive end-expiratory pressure increments during anesthesia in normal lung result in hysteresis and greater numbers of smaller aerated airspaces. Anesthesiology (2013) 0.80
Sustained therapeutic hypercapnia attenuates pulmonary arterial Rho-kinase activity and ameliorates chronic hypoxic pulmonary hypertension in juvenile rats. Am J Physiol Heart Circ Physiol (2012) 0.79
Corticosteroids for septic shock. N Engl J Med (2008) 0.79
Hypocapnia attenuates mesenteric ischemia-reperfusion injury in a rat model. Can J Anaesth (2005) 0.79
Spontaneous Effort During Mechanical Ventilation: Maximal Injury With Less Positive End-Expiratory Pressure. Crit Care Med (2016) 0.79
Synthesis and evaluation of indenopyrazoles as cyclin-dependent kinase inhibitors. 3. Structure activity relationships at C3(1,2). J Med Chem (2002) 0.78
Mechanical ventilation effect on surfactant content, function, and lung compliance in the newborn rat. Pediatr Res (2004) 0.78
Prevention of pain from propofol injection. BMJ (2011) 0.78
Visualizing the Propagation of Acute Lung Injury. Anesthesiology (2016) 0.78
Treatment of life-threatening post-haemorrhagic anaemia with cell-free haemoglobin solution in an adolescent Jehovah's Witness. Br J Haematol (2002) 0.77
Hypercapnia in acute illness: sometimes good, sometimes not. Crit Care Med (2011) 0.77
Hypoxemia during surgery: learning from history, science, and current practice. Can J Anaesth (2010) 0.77
Ventilator-induced lung injury: the role of gene activation. Curr Opin Crit Care (2012) 0.77
Vascular remodeling protects against ventilator-induced lung injury in the in vivo rat. Anesthesiology (2008) 0.76
Ventilator-induced diaphragm dysfunction: from mice (hopefully) to men. Anesthesiology (2012) 0.75
In reply. Anesthesiology (2015) 0.75
Hypocapnia and the injured brain: Evidence for harm. Crit Care Med (2011) 0.75
Rebuttal from Gerard F. Curley, John G. Laffey and Brian P. Kavanagh. J Physiol (2013) 0.75
Compartmentalization of lung injury--atelectasis versus overstretch. Crit Care Med (2014) 0.75
Pediatric ventilation -- towards simpler approaches for complex diseases. Paediatr Anaesth (2005) 0.75