Published in Nat Biotechnol on April 12, 2009
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Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency. Cell Stem Cell (2011) 6.11
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Integration-free iPS cells engineered using human artificial chromosome vectors. PLoS One (2011) 1.13
Technological overview of iPS induction from human adult somatic cells. Curr Gene Ther (2013) 1.13
microRNA-29b is a novel mediator of Sox2 function in the regulation of somatic cell reprogramming. Cell Res (2012) 1.12
Epigenetic modulation of miR-122 facilitates human embryonic stem cell self-renewal and hepatocellular carcinoma proliferation. PLoS One (2011) 1.11
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Assessing iPSC reprogramming methods for their suitability in translational medicine. J Cell Biochem (2012) 1.07
MicroRNA-mediated posttranscriptional regulation is required for maintaining undifferentiated properties of blastoderm and primordial germ cells in chickens. Proc Natl Acad Sci U S A (2011) 1.05
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Two miRNA clusters reveal alternative paths in late-stage reprogramming. Cell Stem Cell (2014) 1.04
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microRNA control of mouse and human pluripotent stem cell behavior. Annu Rev Cell Dev Biol (2013) 1.02
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Role of microRNA-138 as a potential tumor suppressor in head and neck squamous cell carcinoma. Int Rev Cell Mol Biol (2013) 1.00
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Deconstructing mitochondrial dysfunction in Alzheimer disease. Oxid Med Cell Longev (2013) 0.99
MiR-25 regulates Wwp2 and Fbxw7 and promotes reprogramming of mouse fibroblast cells to iPSCs. PLoS One (2012) 0.99
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A genome-wide RNAi screen identifies opposing functions of Snai1 and Snai2 on the Nanog dependency in reprogramming. Mol Cell (2014) 0.94
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Generation of induced pluripotent stem cells from human renal proximal tubular cells with only two transcription factors, OCT4 and SOX2. J Biol Chem (2012) 0.93
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Sodium butyrate promotes generation of human induced pluripotent stem cells through induction of the miR302/367 cluster. Stem Cells Dev (2013) 0.93
Induced multipotency in adult keratinocytes through down-regulation of ΔNp63 or DGCR8. Proc Natl Acad Sci U S A (2014) 0.92
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Lineage determinants in early endocrine development. Semin Cell Dev Biol (2012) 0.92
Matched miRNA and mRNA signatures from an hESC-based in vitro model of pancreatic differentiation reveal novel regulatory interactions. J Cell Sci (2013) 0.92
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Identification of Oct4-activating compounds that enhance reprogramming efficiency. Proc Natl Acad Sci U S A (2012) 0.91
Sirtuin 1 facilitates generation of induced pluripotent stem cells from mouse embryonic fibroblasts through the miR-34a and p53 pathways. PLoS One (2012) 0.91
Functional screen reveals essential roles of miR-27a/24 in differentiation of embryonic stem cells. EMBO J (2014) 0.91
miR-290/371-Mbd2-Myc circuit regulates glycolytic metabolism to promote pluripotency. EMBO J (2015) 0.91
Embryonic stem cell-derived microvesicles induce gene expression changes in Müller cells of the retina. PLoS One (2012) 0.90
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Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat Biotechnol (2007) 21.93
Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells. Cell (2008) 16.38
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Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse. Cell Stem Cell (2008) 12.45
Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells. Cell Stem Cell (2008) 12.29
A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors. Cell (2006) 11.01
miRiad roles for the miR-17-92 cluster in development and disease. Cell (2008) 8.02
Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation. Nat Rev Genet (2008) 7.30
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Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation. Nat Genet (2008) 5.26
Generation of induced pluripotent stem cells in the absence of drug selection. Cell Stem Cell (2007) 4.94
MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells. Nat Struct Mol Biol (2008) 3.98
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DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal. Nat Genet (2007) 9.25
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Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs. Genes Dev (2008) 7.07
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Reprogramming of a melanoma genome by nuclear transplantation. Genes Dev (2004) 2.75
MicroRNA-29 regulates T-box transcription factors and interferon-γ production in helper T cells. Immunity (2011) 2.71
MicroRNA function is globally suppressed in mouse oocytes and early embryos. Curr Biol (2010) 2.57
Loss of cardiac microRNA-mediated regulation leads to dilated cardiomyopathy and heart failure. Circ Res (2009) 2.44
Targeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzyme. Genome Res (2012) 2.02
Microfluidic-based multiplex qRT-PCR identifies diagnostic and prognostic microRNA signatures in the sera of prostate cancer patients. Cancer Res (2010) 1.89
53BP1 and NFBD1/MDC1-Nbs1 function in parallel interacting pathways activating ataxia-telangiectasia mutated (ATM) in response to DNA damage. Cancer Res (2003) 1.87
53BP1, an activator of ATM in response to DNA damage. DNA Repair (Amst) (2004) 1.84
Cell cycle regulation by MicroRNAs in embryonic stem cells. Cancer Res (2009) 1.69
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Deadly teamwork: neural cancer stem cells and the tumor microenvironment. Cell Stem Cell (2011) 1.49
Distinct requirements of microRNAs in NK cell activation, survival, and function. J Immunol (2010) 1.48
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Estimating the risk of drug-induced proarrhythmia using human induced pluripotent stem cell-derived cardiomyocytes. Toxicol Sci (2011) 1.45
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Sox1 marks an activated neural stem/progenitor cell in the hippocampus. Development (2012) 0.88
Watching reprogramming in real time. Nat Biotechnol (2009) 0.87
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