Published in Trends Genet on January 26, 2010
A compendium of genome-wide associations for cancer: critical synopsis and reappraisal. J Natl Cancer Inst (2010) 2.00
The blood exposome and its role in discovering causes of disease. Environ Health Perspect (2014) 1.27
Phenotypic complexity, measurement bias, and poor phenotypic resolution contribute to the missing heritability problem in genetic association studies. PLoS One (2010) 1.26
Child development and molecular genetics: 14 years later. Child Dev (2012) 1.23
Genome-wide significant associations for variants with minor allele frequency of 5% or less--an overview: A HuGE review. Am J Epidemiol (2010) 1.21
A bayesian method for evaluating and discovering disease loci associations. PLoS One (2011) 1.19
Population growth inflates the per-individual number of deleterious mutations and reduces their mean effect. Genetics (2013) 1.17
Etiologic field effect: reappraisal of the field effect concept in cancer predisposition and progression. Mod Pathol (2014) 1.16
Regularized machine learning in the genetic prediction of complex traits. PLoS Genet (2014) 1.15
Cancer evolution and individual susceptibility. Integr Biol (Camb) (2011) 1.15
A systems-biology approach to modular genetic complexity. Chaos (2010) 1.10
A fast algorithm for learning epistatic genomic relationships. AMIA Annu Symp Proc (2010) 1.08
Population based allele frequencies of disease associated polymorphisms in the Personalized Medicine Research Project. BMC Genet (2010) 1.04
Low-pass genome-wide sequencing and variant inference using identity-by-descent in an isolated human population. Genetics (2011) 0.99
A pri-miR-218 variant and risk of cervical carcinoma in Chinese women. BMC Cancer (2013) 0.96
Estimating single nucleotide polymorphism associations using pedigree data: applications to breast cancer. Br J Cancer (2013) 0.90
Polymorphisms of the Interleukin 6 gene contribute to cervical cancer susceptibility in Eastern Chinese women. Hum Genet (2012) 0.89
Allele-specific deletions in mouse tumors identify Fbxw7 as germline modifier of tumor susceptibility. PLoS One (2012) 0.88
Potentially functional polymorphisms in the CASP7 gene contribute to gastric adenocarcinoma susceptibility in an eastern Chinese population. PLoS One (2013) 0.85
Analyzing heterogeneous complexity in complementary and alternative medicine research: a systems biology solution via parsimony phylogenetics. Forsch Komplementmed (2012) 0.85
A comparative analysis of methods for predicting clinical outcomes using high-dimensional genomic datasets. J Am Med Inform Assoc (2014) 0.84
A pilot genome-wide association study shows genomic variants enriched in the non-tumor cells of patients with well-differentiated neuroendocrine tumors of the ileum. Endocr Relat Cancer (2011) 0.84
Genetic predictors of circulating 25-hydroxyvitamin d and risk of colorectal cancer. Cancer Epidemiol Biomarkers Prev (2013) 0.84
The use of genomic information to optimize cancer chemotherapy. Semin Oncol (2011) 0.84
Cancer heterogeneity: origins and implications for genetic association studies. Trends Genet (2012) 0.83
Special considerations in prognostic research in cancer involving genetic polymorphisms. BMC Med (2013) 0.83
Genetic variants and their interactions in disease risk prediction - machine learning and network perspectives. BioData Min (2013) 0.83
Colorectal adenomas and cancer link to chromosome 13q22.1-13q31.3 in a large family with excess colorectal cancer. J Med Genet (2010) 0.83
The genetics of breast cancer: risk factors for disease. Appl Clin Genet (2011) 0.81
Learning Predictive Interactions Using Information Gain and Bayesian Network Scoring. PLoS One (2015) 0.81
A comparison of methods sensitive to interactions with small main effects. Genet Epidemiol (2012) 0.80
Uncovering hidden variance: pair-wise SNP analysis accounts for additional variance in nicotine dependence. Hum Genet (2010) 0.80
Evaluation of a two-stage framework for prediction using big genomic data. Brief Bioinform (2015) 0.80
LEAP: biomarker inference through learning and evaluating association patterns. Genet Epidemiol (2015) 0.80
Database of genetic studies of bipolar disorder. Psychiatr Genet (2011) 0.80
Genome wide association studies in presence of misclassified binary responses. BMC Genet (2013) 0.79
Multiple primary colorectal cancer: Individual or familial predisposition? World J Gastrointest Oncol (2015) 0.78
Unraveling heterogeneous susceptibility and the evolution of breast cancer using a systems biology approach. Genome Biol (2015) 0.78
Integrative genomic analysis for the discovery of biomarkers in prostate cancer. Biomark Insights (2014) 0.78
Rapid dissemination of RET-transgene-driven melanoma in the presence of non-obese diabetic alleles: Critical roles of Dectin-1 and Nitric-oxide synthase type 2. Oncoimmunology (2015) 0.77
Does radioiodine therapy in patients with differentiated thyroid cancer increase the frequency of another malignant neoplasm? ISRN Oncol (2011) 0.77
No boundaries: genomes, organisms, and ecological interactions responsible for divergence and reproductive isolation. J Hered (2014) 0.77
XRCC1 Arg194Trp and Arg399Gln polymorphisms and risk of extrahepatic cholangiocarcinoma: a hospital-based case-control study in China. Int J Clin Exp Med (2015) 0.75
Discovering causal interactions using Bayesian network scoring and information gain. BMC Bioinformatics (2016) 0.75
Identification of Stmm3 locus conferring resistance to late-stage chemically induced skin papillomas on mouse chromosome 4 by congenic mapping and allele-specific alteration analysis. Exp Anim (2014) 0.75
Artificial neural networks modeling gene-environment interaction. BMC Genet (2012) 0.75
The Ser326Cys polymorphism of hOGG1 is associated with intrahepatic cholangiocarcinoma susceptibility in a Chinese population. Int J Clin Exp Med (2015) 0.75
Extensive genomic variability of knops blood group polymorphisms is associated with sickle cell disease in Africa. Evol Bioinform Online (2015) 0.75
Using haplotype analysis to elucidate significant associations between genes and Hodgkin lymphoma. Leuk Res (2012) 0.75
Evaluating de novo locus-disease discoveries in GWAS using the signal-to-noise ratio. AMIA Annu Symp Proc (2011) 0.75
Congenic mapping and allele-specific alteration analysis of Stmm1 locus conferring resistance to early-stage chemically induced skin papillomas. PLoS One (2014) 0.75
Binomial Mixture Model Based Association Testing to Account for Genetic Heterogeneity for GWAS. Genet Epidemiol (2016) 0.75
To control false positives in gene-gene interaction analysis: two novel conditional entropy-based approaches. PLoS One (2013) 0.75
A weighted U statistic for association analyses considering genetic heterogeneity. Stat Med (2016) 0.75
Major milestones in translational oncology. BMC Med (2016) 0.75
Finding the missing heritability of complex diseases. Nature (2009) 67.95
Exome sequencing identifies the cause of a mendelian disorder. Nat Genet (2009) 32.06
Genome-wide association study identifies novel breast cancer susceptibility loci. Nature (2007) 29.23
Environmental and heritable factors in the causation of cancer--analyses of cohorts of twins from Sweden, Denmark, and Finland. N Engl J Med (2000) 25.49
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer. Nat Genet (2007) 22.96
Common genetic variation and human traits. N Engl J Med (2009) 21.03
Integrated detection and population-genetic analysis of SNPs and copy number variation. Nat Genet (2008) 19.55
Multiple loci identified in a genome-wide association study of prostate cancer. Nat Genet (2008) 17.65
Replication validity of genetic association studies. Nat Genet (2001) 16.30
Multiple newly identified loci associated with prostate cancer susceptibility. Nat Genet (2008) 15.43
A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21. Nat Genet (2007) 11.62
Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor-positive breast cancer. Nat Genet (2007) 10.81
An evaluation of statistical approaches to rare variant analysis in genetic association studies. Genet Epidemiol (2010) 10.54
Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24. Nat Genet (2007) 9.88
Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations. Nat Genet (2002) 9.71
Polygenes, risk prediction, and targeted prevention of breast cancer. N Engl J Med (2008) 9.64
Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1. Nat Genet (2009) 8.44
A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1). Nat Genet (2009) 8.39
Common variants on chromosome 5p12 confer susceptibility to estrogen receptor-positive breast cancer. Nat Genet (2008) 7.65
Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2. Nat Genet (2009) 7.30
Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer. Nat Genet (2008) 6.97
Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21. Nat Genet (2008) 6.75
A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3. Nat Genet (2008) 6.26
A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk. Nat Genet (2007) 6.02
A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. Am J Hum Genet (2009) 5.62
Common 5p15.33 and 6p21.33 variants influence lung cancer risk. Nat Genet (2008) 5.43
Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility. Nat Genet (2009) 5.06
Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33. Proc Natl Acad Sci U S A (2008) 4.76
Validating, augmenting and refining genome-wide association signals. Nat Rev Genet (2009) 4.56
The emerging landscape of breast cancer susceptibility. Nat Genet (2008) 4.27
New common variants affecting susceptibility to basal cell carcinoma. Nat Genet (2009) 4.15
CHEK2*1100delC and susceptibility to breast cancer: a collaborative analysis involving 10,860 breast cancer cases and 9,065 controls from 10 studies. Am J Hum Genet (2004) 3.97
Genome-wide association study identifies three loci associated with melanoma risk. Nat Genet (2009) 3.89
Autosomal dominant polycystic kidney disease: the last 3 years. Kidney Int (2009) 3.66
Environmental and heritable causes of cancer among 9.6 million individuals in the Swedish Family-Cancer Database. Int J Cancer (2002) 3.55
Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations. Nat Genet (2009) 3.46
Genome-wide significance for dense SNP and resequencing data. Genet Epidemiol (2008) 3.26
A major lung cancer susceptibility locus maps to chromosome 6q23-25. Am J Hum Genet (2004) 3.05
Reaching new heights: insights into the genetics of human stature. Trends Genet (2008) 2.89
Risk of estrogen receptor-positive and -negative breast cancer and single-nucleotide polymorphism 2q35-rs13387042. J Natl Cancer Inst (2009) 2.88
Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer. Nat Genet (2009) 2.85
A genome-wide association study of testicular germ cell tumor. Nat Genet (2009) 2.79
Genomics: when the smoke clears ... Nature (2008) 2.72
Cigarette smoking and subsequent risk of lung cancer in men and women: analysis of a prospective cohort study. Lancet Oncol (2008) 2.71
Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study. Cancer Res (2009) 2.63
Next generation disparities in human genomics: concerns and remedies. Trends Genet (2009) 2.53
Papillary thyroid carcinoma associated with papillary renal neoplasia: genetic linkage analysis of a distinct heritable tumor syndrome. J Clin Endocrinol Metab (2000) 2.52
A genome wide linkage search for breast cancer susceptibility genes. Genes Chromosomes Cancer (2006) 2.35
Genome-wide linkage screen for testicular germ cell tumour susceptibility loci. Hum Mol Genet (2006) 2.23
Genome-wide association studies, field synopses, and the development of the knowledge base on genetic variation and human diseases. Am J Epidemiol (2009) 2.15
Merging and emerging cohorts: necessary but not sufficient. Nature (2007) 1.96
Lynch syndrome genes. Fam Cancer (2005) 1.94
A subset of familial colorectal neoplasia kindreds linked to chromosome 9q22.2-31.2. Proc Natl Acad Sci U S A (2003) 1.84
A genome-wide association study of breast and prostate cancer in the NHLBI's Framingham Heart Study. BMC Med Genet (2007) 1.81
A gene predisposing to familial thyroid tumors with cell oxyphilia maps to chromosome 19p13.2. Am J Hum Genet (1998) 1.81
Polygenic determinants of severe hypertriglyceridemia. Hum Mol Genet (2008) 1.77
Localization of a susceptibility gene for familial nonmedullary thyroid carcinoma to chromosome 2q21. Am J Hum Genet (2001) 1.68
The molecular genetics of Usher syndrome. Clin Genet (2003) 1.68
Researching genetic versus nongenetic determinants of disease: a comparison and proposed unification. Sci Transl Med (2009) 1.67
Evidence for a colorectal cancer susceptibility locus on chromosome 3q21-q24 from a high-density SNP genome-wide linkage scan. Hum Mol Genet (2006) 1.42
Refinement of the basis and impact of common 11q23.1 variation to the risk of developing colorectal cancer. Hum Mol Genet (2008) 1.40
Prediction of Lynch syndrome in consecutive patients with colorectal cancer. J Natl Cancer Inst (2009) 1.40
Evidence of linkage to chromosome 9q22.33 in colorectal cancer kindreds from the United Kingdom. Cancer Res (2006) 1.37
Frequency of hereditary non-polyposis colorectal cancer and other colorectal cancer familial forms in Spain: a multicentre, prospective, nationwide study. Eur J Gastroenterol Hepatol (2004) 1.33
Commentary: grading the credibility of molecular evidence for complex diseases. Int J Epidemiol (2006) 1.23
Differential features of colorectal cancers fulfilling Amsterdam criteria without involvement of the mutator pathway. Clin Cancer Res (2005) 1.20
Linkage analysis in a large Swedish family supports the presence of a susceptibility locus for adenoma and colorectal cancer on chromosome 9q22.32-31.1. J Med Genet (2006) 1.18
Population-wide generalizability of genome-wide discovered associations. J Natl Cancer Inst (2009) 1.18
Is replication the gold standard for validating genome-wide association findings? PLoS One (2008) 1.18
Common familial colorectal cancer linked to chromosome 7q31: a genome-wide analysis. Cancer Res (2008) 1.17
Calibration of credibility of agnostic genome-wide associations. Am J Med Genet B Neuropsychiatr Genet (2008) 1.12
Schizophrenia genetics: new insights from new approaches. Br Med Bull (2009) 1.11
Genetic risk information for common diseases may indeed be already useful for prevention and early detection. Eur J Clin Invest (2010) 1.06
Genomewide high-density SNP linkage analysis of non-BRCA1/2 breast cancer families identifies various candidate regions and has greater power than microsatellite studies. BMC Genomics (2007) 1.01
The genetic concept of vitiligo. J Dermatol Sci (2005) 1.00
Genome-wide linkage scan reveals three putative breast-cancer-susceptibility loci. Am J Hum Genet (2009) 0.99
Genome-wide linkage scan for colorectal cancer susceptibility genes supports linkage to chromosome 3q. BMC Cancer (2008) 0.99
Mapping a new familial thyroid epithelial neoplasia susceptibility locus to chromosome 8p23.1-p22 by high-density single-nucleotide polymorphism genome-wide linkage analysis. J Clin Endocrinol Metab (2008) 0.96
Genome-wide scanning for linkage in Finnish breast cancer families. Eur J Hum Genet (2004) 0.95
Nicotine dependence may link the 15q25 locus to lung cancer risk. Carcinogenesis (2009) 0.93
Genome-wide linkage scan for breast cancer susceptibility loci in Swedish hereditary non-BRCA1/2 families: suggestive linkage to 10q23.32-q25.3. Genes Chromosomes Cancer (2007) 0.93
Current clinical selection strategies for identification of hereditary non-polyposis colorectal cancer families are inadequate: a meta-analysis. Clin Genet (2004) 0.92
Diet, nutrition and cancer: public, media and scientific confusion. Ann Oncol (2008) 0.90
Linkage and association: basic concepts. Adv Genet (2008) 0.85
Letter: Genetic heterogeneity recognized by Waardenburgh in 1935. Am J Hum Genet (1976) 0.76
Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nat Rev Genet (2008) 30.94
The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. BMJ (2009) 22.18
The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. PLoS Med (2009) 21.74
Power failure: why small sample size undermines the reliability of neuroscience. Nat Rev Neurosci (2013) 13.37
Systematic review of the empirical evidence of study publication bias and outcome reporting bias. PLoS One (2008) 13.32
The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. Ann Intern Med (2009) 12.16
The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. J Clin Epidemiol (2009) 11.80
The case of the misleading funnel plot. BMJ (2006) 8.26
Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of observational studies and randomised trials. BMJ (2014) 7.21
Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials. BMJ (2011) 6.80
Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database. Nat Genet (2008) 6.71
Sensitivity of between-study heterogeneity in meta-analysis: proposed metrics and empirical evaluation. Int J Epidemiol (2008) 5.88
Research grants: Conform and be funded. Nature (2012) 5.83
Correlation of quality measures with estimates of treatment effect in meta-analyses of randomized controlled trials. JAMA (2002) 5.81
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet (2012) 5.48
Assessment of claims of improved prediction beyond the Framingham risk score. JAMA (2009) 5.36
Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies. Nat Genet (2009) 5.32
Why current publication practices may distort science. PLoS Med (2008) 5.09
Evaluation of networks of randomized trials. Stat Methods Med Res (2007) 4.70
Predictive ability of DNA microarrays for cancer outcomes and correlates: an empirical assessment. Lancet (2003) 4.58
Number of published systematic reviews and global burden of disease: database analysis. BMJ (2003) 4.53
The PRISMA extension statement for reporting of systematic reviews incorporating network meta-analyses of health care interventions: checklist and explanations. Ann Intern Med (2015) 4.49
Neoadjuvant versus adjuvant systemic treatment in breast cancer: a meta-analysis. J Natl Cancer Inst (2005) 4.48
Heterogeneity testing in meta-analysis of genome searches. Genet Epidemiol (2005) 4.45
Public availability of published research data in high-impact journals. PLoS One (2011) 4.41
Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database. PLoS Genet (2012) 4.27
Relative citation impact of various study designs in the health sciences. JAMA (2005) 4.19
Comparisons of established risk prediction models for cardiovascular disease: systematic review. BMJ (2012) 4.16
Graphical methods and numerical summaries for presenting results from multiple-treatment meta-analysis: an overview and tutorial. J Clin Epidemiol (2010) 4.10
The emergence of translational epidemiology: from scientific discovery to population health impact. Am J Epidemiol (2010) 4.04
Methods for meta-analysis in genetic association studies: a review of their potential and pitfalls. Hum Genet (2007) 3.92
Predicting death: an empirical evaluation of predictive tools for mortality. Arch Intern Med (2011) 3.81
Seven new loci associated with age-related macular degeneration. Nat Genet (2013) 3.81
Relation between burden of disease and randomised evidence in sub-Saharan Africa: survey of research. BMJ (2002) 3.78
Translation of highly promising basic science research into clinical applications. Am J Med (2003) 3.74
Influence of reported study design characteristics on intervention effect estimates from randomized, controlled trials. Ann Intern Med (2012) 3.63
Overlapping meta-analyses on the same topic: survey of published studies. BMJ (2013) 3.57
Empirical evaluation of very large treatment effects of medical interventions. JAMA (2012) 3.48
Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study. Lancet (2012) 3.48
Assessing and reporting heterogeneity in treatment effects in clinical trials: a proposal. Trials (2010) 3.45
Selective reporting biases in cancer prognostic factor studies. J Natl Cancer Inst (2005) 3.41
Meta-analysis in genome-wide association studies. Pharmacogenomics (2009) 3.39
Association of LRRK2 exonic variants with susceptibility to Parkinson's disease: a case-control study. Lancet Neurol (2011) 3.36
Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: a metaanalysis. Am J Gastroenterol (2004) 3.28
Medicine. Life cycle of translational research for medical interventions. Science (2008) 3.12
The Scientific Foundation for personal genomics: recommendations from a National Institutes of Health-Centers for Disease Control and Prevention multidisciplinary workshop. Genet Med (2009) 2.91
Survival with aromatase inhibitors and inactivators versus standard hormonal therapy in advanced breast cancer: meta-analysis. J Natl Cancer Inst (2006) 2.91
HEGESMA: genome search meta-analysis and heterogeneity testing. Bioinformatics (2005) 2.81
Collaborative meta-analysis: associations of 150 candidate genes with osteoporosis and osteoporotic fracture. Ann Intern Med (2009) 2.80
The association between common vitamin D receptor gene variations and osteoporosis: a participant-level meta-analysis. Ann Intern Med (2006) 2.74
Transparent Reporting of a multivariable prediction model for Individual Prognosis or Diagnosis (TRIPOD): explanation and elaboration. Ann Intern Med (2015) 2.71
Evaluation of excess significance bias in animal studies of neurological diseases. PLoS Biol (2013) 2.70
Extended-interval aminoglycoside administration for children: a meta-analysis. Pediatrics (2004) 2.60
Meta-analysis of the association of beta2-adrenergic receptor polymorphisms with asthma phenotypes. J Allergy Clin Immunol (2005) 2.59
Meta-analysis methods for genome-wide association studies and beyond. Nat Rev Genet (2013) 2.58
Reporting and interpretation of SF-36 outcomes in randomised trials: systematic review. BMJ (2009) 2.57
Transforming epidemiology for 21st century medicine and public health. Cancer Epidemiol Biomarkers Prev (2013) 2.56
Comparative effectiveness of exercise and drug interventions on mortality outcomes: metaepidemiological study. BMJ (2013) 2.52
Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis. JAMA (2008) 2.52
Effects of interventions on survival in acute respiratory distress syndrome: an umbrella review of 159 published randomized trials and 29 meta-analyses. Intensive Care Med (2014) 2.51
Origin and funding of the most frequently cited papers in medicine: database analysis. BMJ (2006) 2.47
Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand. Arthritis Rheum (2009) 2.47
Claims of sex differences: an empirical assessment in genetic associations. JAMA (2007) 2.46
Almost all articles on cancer prognostic markers report statistically significant results. Eur J Cancer (2007) 2.46
Strengthening the reporting of genetic association studies (STREGA): an extension of the strengthening the reporting of observational studies in epidemiology (STROBE) statement. J Clin Epidemiol (2009) 2.45
Systematic evaluation of environmental factors: persistent pollutants and nutrients correlated with serum lipid levels. Int J Epidemiol (2012) 2.42
Sources of funding for Nobel Prize-winning work: public or private? FASEB J (2010) 2.42
Comparison of evidence on harms of medical interventions in randomized and nonrandomized studies. CMAJ (2006) 2.40
STrengthening the REporting of Genetic Association Studies (STREGA): an extension of the STROBE statement. PLoS Med (2009) 2.39
18F-fluorodeoxyglucose positron emission tomography to evaluate cervical node metastases in patients with head and neck squamous cell carcinoma: a meta-analysis. J Natl Cancer Inst (2008) 2.32
International ranking systems for universities and institutions: a critical appraisal. BMC Med (2007) 2.31
Can trial sequential monitoring boundaries reduce spurious inferences from meta-analyses? Int J Epidemiol (2008) 2.31
Treating anemia early in renal failure patients slows the decline of renal function: a randomized controlled trial. Kidney Int (2004) 2.30
A field synopsis on low-penetrance variants in DNA repair genes and cancer susceptibility. J Natl Cancer Inst (2008) 2.29
Transcription deregulation at the 15q25 locus in association with lung adenocarcinoma risk. Clin Cancer Res (2009) 2.28
How to use an article reporting a multiple treatment comparison meta-analysis. JAMA (2012) 2.28
STrengthening the Reporting of OBservational studies in Epidemiology--Molecular Epidemiology STROBE-ME: an extension of the STROBE statement. J Clin Epidemiol (2011) 2.24
Joint European League Against Rheumatism and European Renal Association-European Dialysis and Transplant Association (EULAR/ERA-EDTA) recommendations for the management of adult and paediatric lupus nephritis. Ann Rheum Dis (2012) 2.21
Hardy-Weinberg equilibrium in genetic association studies: an empirical evaluation of reporting, deviations, and power. Eur J Hum Genet (2005) 2.21
Survival and disease-progression benefits with treatment regimens for advanced colorectal cancer: a meta-analysis. Lancet Oncol (2007) 2.19
A nutrient-wide association study on blood pressure. Circulation (2012) 2.19
Local literature bias in genetic epidemiology: an empirical evaluation of the Chinese literature. PLoS Med (2005) 2.18
Large-scale replication and heterogeneity in Parkinson disease genetic loci. Neurology (2012) 2.18
Genome-wide association studies, field synopses, and the development of the knowledge base on genetic variation and human diseases. Am J Epidemiol (2009) 2.15
Multiple-treatments meta-analysis of chemotherapy and targeted therapies in advanced breast cancer. J Natl Cancer Inst (2008) 2.15
What should the genome-wide significance threshold be? Empirical replication of borderline genetic associations. Int J Epidemiol (2011) 2.13
Modern health care as a game theory problem. Eur J Clin Invest (2015) 2.09
Percutaneous coronary intervention versus conservative therapy in nonacute coronary artery disease: a meta-analysis. Circulation (2005) 2.06
Ensuring the integrity of clinical practice guidelines: a tool for protecting patients. BMJ (2013) 2.06
US studies may overestimate effect sizes in softer research. Proc Natl Acad Sci U S A (2013) 2.06
A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22. Arthritis Rheum (2010) 2.02
Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration. Hum Mol Genet (2011) 1.98
Prognostic effect size of cardiovascular biomarkers in datasets from observational studies versus randomised trials: meta-epidemiology study. BMJ (2011) 1.97
Exploring the geometry of treatment networks. Ann Intern Med (2008) 1.95
Lack of replication of thirteen single-nucleotide polymorphisms implicated in Parkinson's disease: a large-scale international study. Lancet Neurol (2006) 1.92
Optimal timing of coronary angiography and potential intervention in non-ST-elevation acute coronary syndromes. Eur Heart J (2010) 1.91
Persistence of contradicted claims in the literature. JAMA (2007) 1.90
Replication in genome-wide association studies. Stat Sci (2009) 1.89
Meta-analysis: test performance of ultrasonography for giant-cell arteritis. Ann Intern Med (2005) 1.88