Published in BMC Syst Biol on June 26, 2009
Cooperative and individualistic functions of the microRNAs in the miR-23a~27a~24-2 cluster and its implication in human diseases. Mol Cancer (2010) 2.14
Regulation of angiogenesis and choroidal neovascularization by members of microRNA-23~27~24 clusters. Proc Natl Acad Sci U S A (2011) 2.10
MiRNA-miRNA synergistic network: construction via co-regulating functional modules and disease miRNA topological features. Nucleic Acids Res (2010) 1.94
A novel computational framework for simultaneous integration of multiple types of genomic data to identify microRNA-gene regulatory modules. Bioinformatics (2011) 1.68
Computational approaches for microRNA studies: a review. Mamm Genome (2009) 1.39
c-MYC-regulated miR-23a/24-2/27a cluster promotes mammary carcinoma cell invasion and hepatic metastasis by targeting Sprouty2. J Biol Chem (2013) 1.37
Genomic organization of microRNAs. J Cell Physiol (2010) 1.35
MIR@NT@N: a framework integrating transcription factors, microRNAs and their targets to identify sub-network motifs in a meta-regulation network model. BMC Bioinformatics (2011) 1.33
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MicroRNAs in cancer treatment and prognosis. Am J Cancer Res (2012) 1.17
MicroRNAs coordinately regulate protein complexes. BMC Syst Biol (2011) 1.17
Biological robustness and the role of microRNAs: a network perspective. Curr Top Dev Biol (2012) 1.14
Identifying multi-layer gene regulatory modules from multi-dimensional genomic data. Bioinformatics (2012) 1.11
microRNAs: innovative targets for cerebral ischemia and stroke. Curr Drug Targets (2013) 1.10
Effects of the miR-143/-145 microRNA cluster on the colon cancer proteome and transcriptome. J Proteome Res (2012) 1.03
Regulatory coordination of clustered microRNAs based on microRNA-transcription factor regulatory network. BMC Syst Biol (2011) 0.98
Integrated analysis of miRNA and mRNA expression in childhood medulloblastoma compared with neural stem cells. PLoS One (2011) 0.93
A systematic screen reveals MicroRNA clusters that significantly regulate four major signaling pathways. PLoS One (2012) 0.92
MicroRNAs in bovine adipogenesis: genomic context, expression and function. BMC Genomics (2014) 0.88
Preferential regulation of stably expressed genes in the human genome suggests a widespread expression buffering role of microRNAs. BMC Genomics (2012) 0.88
Identifying dysfunctional miRNA-mRNA regulatory modules by inverse activation, cofunction, and high interconnection of target genes: a case study of glioblastoma. Neuro Oncol (2013) 0.87
Principles of miRNA-target regulation in metazoan models. Int J Mol Sci (2013) 0.86
A novel biclustering algorithm for the discovery of meaningful biological correlations between microRNAs and their target genes. BMC Bioinformatics (2013) 0.85
A network-biology perspective of microRNA function and dysfunction in cancer. Nat Rev Genet (2016) 0.85
Identification of senescence-inducing microRNAs in normal human keratinocytes. Int J Oncol (2011) 0.83
miRNA functional synergistic network analysis of mice with ischemic stroke. Neurol Sci (2014) 0.83
Integration of miRNA and protein profiling reveals coordinated neuroadaptations in the alcohol-dependent mouse brain. PLoS One (2013) 0.81
MicroRNA regulation of molecular pathways as a generic mechanism and as a core disease phenotype. Oncotarget (2015) 0.79
Microevolution of nematode miRNAs reveals diverse modes of selection. Genome Biol Evol (2014) 0.79
microRNAs in the Same Clusters Evolve to Coordinately Regulate Functionally Related Genes. Mol Biol Evol (2016) 0.78
A systematic analysis of a mi-RNA inter-pathway regulatory motif. J Clin Bioinforma (2013) 0.77
Annotation of the goat genome using next generation sequencing of microRNA expressed by the lactating mammary gland: comparison of three approaches. BMC Genomics (2015) 0.76
Computational developments in microRNA-regulated protein-protein interactions. BMC Syst Biol (2014) 0.76
SpidermiR: An R/Bioconductor Package for Integrative Analysis with miRNA Data. Int J Mol Sci (2017) 0.75
ceRNA crosstalk stabilizes protein expression and affects the correlation pattern of interacting proteins. Sci Rep (2017) 0.75
Functional interactions among members of the miR-17-92 cluster in lymphocyte development, differentiation and malignant transformation. Int Immunopharmacol (2015) 0.75
Network Properties for Ranking Predicted miRNA Targets in Breast Cancer. Adv Bioinformatics (2010) 0.75
MicroRNAs: genomics, biogenesis, mechanism, and function. Cell (2004) 198.59
MicroRNA expression profiles classify human cancers. Nature (2005) 69.12
The functions of animal microRNAs. Nature (2004) 64.85
miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res (2006) 39.25
miRBase: tools for microRNA genomics. Nucleic Acids Res (2007) 38.61
The impact of microRNAs on protein output. Nature (2008) 32.39
c-Myc-regulated microRNAs modulate E2F1 expression. Nature (2005) 31.81
Finding and evaluating community structure in networks. Phys Rev E Stat Nonlin Soft Matter Phys (2004) 24.12
MicroRNA genes are transcribed by RNA polymerase II. EMBO J (2004) 20.65
MicroRNA maturation: stepwise processing and subcellular localization. EMBO J (2002) 19.47
Vertebrate microRNA genes. Science (2003) 17.42
Development of human protein reference database as an initial platform for approaching systems biology in humans. Genome Res (2003) 14.79
Identification of mammalian microRNA host genes and transcription units. Genome Res (2004) 14.63
Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes. RNA (2005) 14.14
Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs. Nat Rev Genet (2004) 12.97
Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters. Cell (2008) 12.29
A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation. Cancer Res (2005) 10.46
Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes. Nat Immunol (2008) 10.42
Transcription and processing of human microRNA precursors. Mol Cell (2004) 8.98
Characterization of microRNA expression profiles in normal human tissues. BMC Genomics (2007) 8.01
Genomics of microRNA. Trends Genet (2006) 7.75
A guide through present computational approaches for the identification of mammalian microRNA targets. Nat Methods (2006) 7.00
RNA polymerase III transcribes human microRNAs. Nat Struct Mol Biol (2006) 6.81
microRNA target predictions across seven Drosophila species and comparison to mammalian targets. PLoS Comput Biol (2005) 6.77
The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans. Dev Cell (2005) 5.90
The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities. Nat Med (2008) 5.74
Clustering and conservation patterns of human microRNAs. Nucleic Acids Res (2005) 4.79
Global and local architecture of the mammalian microRNA-transcription factor regulatory network. PLoS Comput Biol (2007) 4.31
CFinder: locating cliques and overlapping modules in biological networks. Bioinformatics (2006) 4.27
Transgenic over-expression of the microRNA miR-17-92 cluster promotes proliferation and inhibits differentiation of lung epithelial progenitor cells. Dev Biol (2007) 4.16
Probabilistic model of the human protein-protein interaction network. Nat Biotechnol (2005) 3.99
Systematic evaluation of microRNA processing patterns in tissues, cell lines, and tumors. RNA (2007) 3.91
New human and mouse microRNA genes found by homology search. FEBS J (2005) 3.88
Mammalian microRNAs derived from genomic repeats. Trends Genet (2005) 3.60
Functional links between clustered microRNAs: suppression of cell-cycle inhibitors by microRNA clusters in gastric cancer. Nucleic Acids Res (2009) 3.44
Principles of microRNA regulation of a human cellular signaling network. Mol Syst Biol (2006) 3.27
A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation. J Cell Biol (2008) 3.02
Emerging role of miR-106b-25/miR-17-92 clusters in the control of transforming growth factor beta signaling. Cancer Res (2008) 3.01
The expansion of the metazoan microRNA repertoire. BMC Genomics (2006) 2.80
Human microRNA clusters: genomic organization and expression profile in leukemia cell lines. Biochem Biophys Res Commun (2006) 2.65
Mef2-mediated transcription of the miR379-410 cluster regulates activity-dependent dendritogenesis by fine-tuning Pumilio2 protein levels. EMBO J (2009) 2.65
A family of human microRNA genes from miniature inverted-repeat transposable elements. PLoS One (2007) 2.63
Origin and evolution of human microRNAs from transposable elements. Genetics (2007) 2.39
Histone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells. Mol Cell (2009) 2.27
MicroRNAs preferentially target the genes with high transcriptional regulation complexity. Biochem Biophys Res Commun (2006) 1.88
MicroRNA regulation of human protein protein interaction network. RNA (2007) 1.82
Inter- and intra-combinatorial regulation by transcription factors and microRNAs. BMC Genomics (2007) 1.45
A computational screen for mouse signaling pathways targeted by microRNA clusters. RNA (2008) 1.41
Characterization of microRNA-regulated protein-protein interaction network. Proteomics (2008) 1.41
microRNA expression in the aging mouse lung. BMC Genomics (2007) 1.37
Evolution of plant microRNA gene families. Cell Res (2007) 1.30
Computational analysis of biological functions and pathways collectively targeted by co-expressed microRNAs in cancer. BMC Bioinformatics (2007) 1.21
A bootstrap based analysis pipeline for efficient classification of phylogenetically related animal miRNAs. BMC Genomics (2007) 0.96
Mapping copy number variation by population-scale genome sequencing. Nature (2011) 12.55
miRecords: an integrated resource for microRNA-target interactions. Nucleic Acids Res (2008) 8.97
The oyster genome reveals stress adaptation and complexity of shell formation. Nature (2012) 5.30
Whole-genome sequencing in autism identifies hot spots for de novo germline mutation. Cell (2012) 4.03
Sensing movement: microsensors for body motion measurement. Sensors (Basel) (2011) 3.27
Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Nature (2011) 3.19
NONCODE: an integrated knowledge database of non-coding RNAs. Nucleic Acids Res (2005) 3.16
Analysis of Lrrk2 R1628P as a risk factor for Parkinson's disease. Ann Neurol (2008) 2.95
Topological structure analysis of the protein-protein interaction network in budding yeast. Nucleic Acids Res (2003) 2.90
Identification of a novel risk variant in the FUS gene in essential tremor. Neurology (2013) 2.84
NONCODE v3.0: integrative annotation of long noncoding RNAs. Nucleic Acids Res (2011) 2.82
Genomic comparison of the ants Camponotus floridanus and Harpegnathos saltator. Science (2010) 2.78
Large-scale prediction of long non-coding RNA functions in a coding-non-coding gene co-expression network. Nucleic Acids Res (2011) 2.55
NONCODEv4: exploring the world of long non-coding RNA genes. Nucleic Acids Res (2013) 2.37
Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Nat Biotechnol (2011) 2.37
De novo analysis of transcriptome dynamics in the migratory locust during the development of phase traits. PLoS One (2010) 2.19
Large-scale replication and heterogeneity in Parkinson disease genetic loci. Neurology (2012) 2.18
PlantTFDB 2.0: update and improvement of the comprehensive plant transcription factor database. Nucleic Acids Res (2010) 2.09
IMP-4 and OXA beta-lactamases in Acinetobacter baumannii from Singapore. J Antimicrob Chemother (2007) 1.98
Characterization and comparative profiling of the small RNA transcriptomes in two phases of locust. Genome Biol (2009) 1.96
Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade. J Clin Invest (2009) 1.80
Synthesis of well-defined hydrogel networks using click chemistry. Chem Commun (Camb) (2006) 1.79
Organization of the Caenorhabditis elegans small non-coding transcriptome: genomic features, biogenesis, and expression. Genome Res (2005) 1.77
NONCODE v2.0: decoding the non-coding. Nucleic Acids Res (2007) 1.69
US-guided percutaneous microwave coagulation of small breast cancers: a clinical study. Radiology (2012) 1.66
Utilizing sequence intrinsic composition to classify protein-coding and long non-coding transcripts. Nucleic Acids Res (2013) 1.64
Long noncoding RNA MALAT-1 is a new potential therapeutic target for castration resistant prostate cancer. J Urol (2013) 1.64
SLC1A2 variant associated with essential tremor but not Parkinson disease in Chinese subjects. Neurology (2013) 1.61
Glucocerebrosidase mutations and risk of Parkinson disease in Chinese patients. Arch Neurol (2007) 1.58
Multiple LRRK2 variants modulate risk of Parkinson disease: a Chinese multicenter study. Hum Mutat (2010) 1.57
Angiotensin AT2 receptor protects against cerebral ischemia-induced neuronal injury. FASEB J (2005) 1.54
Wild-type and 'a' epitope variants in chronic hepatitis B virus carriers positive for hepatitis B surface antigen and antibody. J Gastroenterol Hepatol (2002) 1.50
Triggering of toll-like receptor-4 in human multiple myeloma cells promotes proliferation and alters cell responses to immune and chemotherapy drug attack. Cancer Biol Ther (2011) 1.50
Methylene blue protects against paraquat-induced acute lung injury in rats. Int Immunopharmacol (2013) 1.47
Long non-coding RNAs function annotation: a global prediction method based on bi-colored networks. Nucleic Acids Res (2012) 1.46
An artificial biomineral formed by incorporation of copolymer micelles in calcite crystals. Nat Mater (2011) 1.46
ncFANs: a web server for functional annotation of long non-coding RNAs. Nucleic Acids Res (2011) 1.46
Shockwaves increase T-cell proliferation and IL-2 expression through ATP release, P2X7 receptors, and FAK activation. Am J Physiol Cell Physiol (2009) 1.46
Road Traffic Injury Prevention Initiatives: A Systematic Review and Metasummary of Effectiveness in Low and Middle Income Countries. PLoS One (2016) 1.46
Genetic associations with coronary heart disease: meta-analyses of 12 candidate genetic variants. Gene (2013) 1.45
Influence of E3 region on conditionally replicative adenovirus mediated cytotoxicity in hepatocellular carcinoma cells. Cancer Biol Ther (2009) 1.45
Adenomatous polyposis coli (APC)-independent regulation of beta-catenin degradation via a retinoid X receptor-mediated pathway. J Biol Chem (2003) 1.43
Transcriptional inhibiton of Hoxd4 expression by miRNA-10a in human breast cancer cells. BMC Mol Biol (2009) 1.42
Remission of rheumatoid arthritis and potential determinants: a national multi-center cross-sectional survey. Clin Rheumatol (2014) 1.41
Intratumor injection of oncolytic adenovirus expressing HSP70 prolonged survival in melanoma B16 bearing mice by enhanced immune response. Cancer Biol Ther (2007) 1.40
Clinically reported heterozygous mutations in the PINK1 kinase domain exert a gene dosage effect. Hum Mutat (2009) 1.39
Gene expression profile of murine long-term reconstituting vs. short-term reconstituting hematopoietic stem cells. Proc Natl Acad Sci U S A (2005) 1.32
NPInter: the noncoding RNAs and protein related biomacromolecules interaction database. Nucleic Acids Res (2006) 1.24
Murine hematopoietic stem cell distribution and proliferation in ablated and nonablated bone marrow transplantation. Blood (2002) 1.21
Utilization of metabolomics to identify serum biomarkers for hepatocellular carcinoma in patients with liver cirrhosis. Anal Chim Acta (2012) 1.20
dbDEMC: a database of differentially expressed miRNAs in human cancers. BMC Genomics (2010) 1.20
PPAR-gamma: therapeutic target for ischemic stroke. Trends Pharmacol Sci (2007) 1.20
Meta-prediction of phosphorylation sites with weighted voting and restricted grid search parameter selection. Nucleic Acids Res (2008) 1.20
The bright side of JNKs-Multitalented mediators in neuronal sprouting, brain development and nerve fiber regeneration. Prog Neurobiol (2006) 1.20
Validity of two self-report measures of sitting time. J Phys Act Health (2011) 1.18
Mitochondrial genomes reveal the global phylogeography and dispersal routes of the migratory locust. Mol Ecol (2012) 1.16
Mutations in LRRK2 increase phosphorylation of peroxiredoxin 3 exacerbating oxidative stress-induced neuronal death. Hum Mutat (2011) 1.16
Regulation of Nur77 expression by β-catenin and its mitogenic effect in colon cancer cells. FASEB J (2010) 1.14
LC-MS based serum metabolomics for identification of hepatocellular carcinoma biomarkers in Egyptian cohort. J Proteome Res (2012) 1.14
NPInter v2.0: an updated database of ncRNA interactions. Nucleic Acids Res (2013) 1.13
Epidemiology of eight common rheumatic diseases in China: a large-scale cross-sectional survey in Beijing. Rheumatology (Oxford) (2011) 1.12
Hypermethylation of EDNRB promoter contributes to the risk of colorectal cancer. Diagn Pathol (2013) 1.11
One-step microfluidic generation of pre-hatching embryo-like core-shell microcapsules for miniaturized 3D culture of pluripotent stem cells. Lab Chip (2013) 1.11
Systems genetics of susceptibility to obesity-induced diabetes in mice. Physiol Genomics (2011) 1.10
Elevated PLA2G7 gene promoter methylation as a gender-specific marker of aging increases the risk of coronary heart disease in females. PLoS One (2013) 1.09
LC-MS profiling of N-Glycans derived from human serum samples for biomarker discovery in hepatocellular carcinoma. J Proteome Res (2014) 1.08
Detection and comparison of epidermal growth factor receptor mutations in cells and fluid of malignant pleural effusion in non-small cell lung cancer. Lung Cancer (2007) 1.08
Prevalence and significance of anti-peptidylarginine deiminase 4 antibodies in rheumatoid arthritis. J Rheumatol (2008) 1.07
Cyclic compressive loading facilitates recovery after eccentric exercise. Med Sci Sports Exerc (2008) 1.05
Bonding the foe - NETting neutrophils immobilize the pro-inflammatory monosodium urate crystals. Front Immunol (2012) 1.04
IL-12 facilitates both the recovery of endogenous hematopoiesis and the engraftment of stem cells after ionizing radiation. Exp Hematol (2007) 1.04
Long non-coding RNAs and complex human diseases. Int J Mol Sci (2013) 1.03
Comparison between early and delayed systemic treatment with candesartan of rats after ischaemic stroke. J Hypertens (2007) 1.03
FTY720 attenuates hepatic ischemia-reperfusion injury in normal and cirrhotic livers. Am J Transplant (2005) 1.03
Sustained blockade of brain AT1 receptors before and after focal cerebral ischemia alleviates neurologic deficits and reduces neuronal injury, apoptosis, and inflammatory responses in the rat. J Cereb Blood Flow Metab (2004) 1.02
RNA interference suppressing PLCE1 gene expression decreases invasive power of human bladder cancer T24 cell line. Cancer Genet Cytogenet (2010) 1.01
The gamma catenin/CBP complex maintains survivin transcription in β-catenin deficient/depleted cancer cells. Curr Cancer Drug Targets (2011) 1.01
MicroRNA-encoding long non-coding RNAs. BMC Genomics (2008) 1.01
Alu-directed transcriptional regulation of some novel miRNAs. BMC Genomics (2009) 1.00
Meta-prediction of protein subcellular localization with reduced voting. Nucleic Acids Res (2007) 1.00
Identifying Hfq-binding small RNA targets in Escherichia coli. Biochem Biophys Res Commun (2006) 1.00
Alpha synuclein promoter and risk of Parkinson's disease: microsatellite and allelic size variability. Neurosci Lett (2003) 1.00
The interactome as a tree--an attempt to visualize the protein-protein interaction network in yeast. Nucleic Acids Res (2004) 1.00
Metabolomic analysis reveals that carnitines are key regulatory metabolites in phase transition of the locusts. Proc Natl Acad Sci U S A (2012) 1.00
Structural basis for the photochemistry of alpha-phycoerythrocyanin. Biochemistry (2007) 0.99
Dose-dependency of massage-like compressive loading on recovery of active muscle properties following eccentric exercise: rabbit study with clinical relevance. Br J Sports Med (2012) 0.99