Published in JAMA on October 12, 2009
A phase II study of DAS181, a novel host directed antiviral for the treatment of influenza infection. J Infect Dis (2012) 2.07
Nowcasting pandemic influenza A/H1N1 2009 hospitalizations in the Netherlands. Eur J Epidemiol (2011) 0.89
Extracorporeal life support for pandemic influenza: the role of extracorporeal membrane oxygenation in pandemic management. J Extra Corpor Technol (2010) 0.86
Limiting severe outcomes and impact on intensive care units of moderate-intermediate 2009 pandemic influenza: role of infectious diseases units. PLoS One (2012) 0.82
Chapter 5. Essential equipment, pharmaceuticals and supplies. Recommendations and standard operating procedures for intensive care unit and hospital preparations for an influenza epidemic or mass disaster. Intensive Care Med (2010) 0.80
[New flu (H1n1): phantom or intensive medicine super-GAU -- a view from the Austrian reality ]. Wien Klin Wochenschr (2010) 0.77
Pandemic influenza: implications for preparation and delivery of critical care services. J Intensive Care Med (2011) 0.77
Predictors of symptoms of posttraumatic stress in Chinese university students during the 2009 H1N1 influenza pandemic. Med Sci Monit (2011) 0.75
Critically Ill patients with 2009 influenza A(H1N1) in Mexico. JAMA (2009) 9.41
Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012. Crit Care Med (2013) 39.56
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med (2008) 31.57
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012. Intensive Care Med (2013) 17.37
A randomized trial of protocol-based care for early septic shock. N Engl J Med (2014) 16.05
Physician staffing patterns and clinical outcomes in critically ill patients: a systematic review. JAMA (2002) 9.89
RIFLE criteria for acute kidney injury are associated with hospital mortality in critically ill patients: a cohort analysis. Crit Care (2006) 9.29
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Intensive Care Med (2007) 8.33
The Surviving Sepsis Campaign: results of an international guideline-based performance improvement program targeting severe sepsis. Crit Care Med (2010) 6.69
National estimates of severe sepsis in United States emergency departments. Crit Care Med (2007) 5.99
Understanding the inflammatory cytokine response in pneumonia and sepsis: results of the Genetic and Inflammatory Markers of Sepsis (GenIMS) Study. Arch Intern Med (2007) 5.65
Nighttime intensivist staffing and mortality among critically ill patients. N Engl J Med (2012) 5.22
Variation in critical care services across North America and Western Europe. Crit Care Med (2008) 5.00
The epidemiology of severe sepsis in children in the United States. Am J Respir Crit Care Med (2002) 4.72
The Surviving Sepsis Campaign: results of an international guideline-based performance improvement program targeting severe sepsis. Intensive Care Med (2010) 4.64
The effect of multidisciplinary care teams on intensive care unit mortality. Arch Intern Med (2010) 4.41
Effect of eritoran, an antagonist of MD2-TLR4, on mortality in patients with severe sepsis: the ACCESS randomized trial. JAMA (2013) 3.78
Risk prediction with procalcitonin and clinical rules in community-acquired pneumonia. Ann Emerg Med (2008) 3.44
Severe sepsis in pre-hospital emergency care: analysis of incidence, care, and outcome. Am J Respir Crit Care Med (2012) 3.36
The epidemiology of mechanical ventilation use in the United States. Crit Care Med (2010) 3.28
Drotrecogin alfa (activated) administration across clinically important subgroups of patients with severe sepsis. Crit Care Med (2003) 3.18
Racial variation in the incidence, care, and outcomes of severe sepsis: analysis of population, patient, and hospital characteristics. Am J Respir Crit Care Med (2007) 3.17
The next generation of sepsis clinical trial designs: what is next after the demise of recombinant human activated protein C?*. Crit Care Med (2014) 3.17
Intensive care unit quality improvement: a "how-to" guide for the interdisciplinary team. Crit Care Med (2006) 3.15
Pneumonia: still the old man's friend? Arch Intern Med (2003) 3.12
Renal failure in the ICU: comparison of the impact of acute renal failure and end-stage renal disease on ICU outcomes. Kidney Int (2002) 3.07
Hospitalized community-acquired pneumonia in the elderly: age- and sex-related patterns of care and outcome in the United States. Am J Respir Crit Care Med (2002) 3.02
The circulatory-respiratory determination of death in organ donation. Crit Care Med (2010) 3.02
Acute kidney injury in non-severe pneumonia is associated with an increased immune response and lower survival. Kidney Int (2009) 2.97
Prospective meta-analysis using individual patient data in intensive care medicine. Intensive Care Med (2009) 2.93
Organizational characteristics, outcomes, and resource use in 78 Brazilian intensive care units: the ORCHESTRA study. Intensive Care Med (2015) 2.92
Three-year outcomes for Medicare beneficiaries who survive intensive care. JAMA (2010) 2.87
An Official ATS/AACN/ACCP/ESICM/SCCM Policy Statement: Responding to Requests for Potentially Inappropriate Treatments in Intensive Care Units. Am J Respir Crit Care Med (2015) 2.86
The association of sepsis syndrome and organ dysfunction with mortality in emergency department patients with suspected infection. Ann Emerg Med (2006) 2.84
The adult respiratory distress syndrome cognitive outcomes study: long-term neuropsychological function in survivors of acute lung injury. Am J Respir Crit Care Med (2012) 2.72
Practical guidance for evidence-based ICU family conferences. Chest (2008) 2.68
Trends in the epidemiology of pediatric severe sepsis*. Pediatr Crit Care Med (2013) 2.67
Critical care medicine training and certification for emergency physicians. Ann Emerg Med (2005) 2.67
End-of-life care for the critically ill: A national intensive care unit survey. Crit Care Med (2006) 2.61
What are cancer centers advertising to the public?: a content analysis. Ann Intern Med (2014) 2.50
Disability among elderly survivors of mechanical ventilation. Am J Respir Crit Care Med (2010) 2.50
Effects of drotrecogin alfa (activated) on organ dysfunction in the PROWESS trial. Crit Care Med (2003) 2.44
Harmonizing international trials of early goal-directed resuscitation for severe sepsis and septic shock: methodology of ProCESS, ARISE, and ProMISe. Intensive Care Med (2013) 2.44
Prioritizing the organization and management of intensive care services in the United States: the PrOMIS Conference. Crit Care Med (2007) 2.42
Surrogate decision-makers' perspectives on discussing prognosis in the face of uncertainty. Am J Respir Crit Care Med (2008) 2.40
Relationship between staff perceptions of hospital norms and hospital-level end-of-life treatment intensity. J Palliat Med (2007) 2.39
The pressure to withhold or withdraw life-sustaining therapy from critically ill patients in the United States. Am J Respir Crit Care Med (2007) 2.39
Long-term mortality and medical care charges in patients with severe sepsis. Crit Care Med (2003) 2.39
Inflammatory markers at hospital discharge predict subsequent mortality after pneumonia and sepsis. Am J Respir Crit Care Med (2008) 2.37
Is survival better at hospitals with higher "end-of-life" treatment intensity? Med Care (2010) 2.35
A randomized, double-blind, placebo-controlled trial of TAK-242 for the treatment of severe sepsis. Crit Care Med (2010) 2.31
Survival after liver transplantation in the United States: a disease-specific analysis of the UNOS database. Liver Transpl (2004) 2.31
Growth of intensive care unit resource use and its estimated cost in Medicare. Crit Care Med (2008) 2.31
Severe sepsis epidemiology: sampling, selection, and society. Crit Care (2004) 2.28
Infection rate and acute organ dysfunction risk as explanations for racial differences in severe sepsis. JAMA (2010) 2.27
"It's not just what the doctor tells me:" factors that influence surrogate decision-makers' perceptions of prognosis. Crit Care Med (2010) 2.25
Perceptions of safety culture vary across the intensive care units of a single institution. Crit Care Med (2007) 2.24
Hospital deaths in patients with sepsis from 2 independent cohorts. JAMA (2014) 2.23
Plasma neutrophil gelatinase-associated lipocalin predicts recovery from acute kidney injury following community-acquired pneumonia. Kidney Int (2011) 2.22
Posttraumatic stress and complicated grief in family members of patients in the intensive care unit. J Gen Intern Med (2008) 2.12
Critical care medicine training and certification for emergency physicians. Crit Care Med (2005) 2.12
Haloperidol use is associated with lower hospital mortality in mechanically ventilated patients. Crit Care Med (2005) 2.11
Severe sepsis and septic shock. N Engl J Med (2013) 2.10
An official American Thoracic Society workshop report: assessment and palliative management of dyspnea crisis. Ann Am Thorac Soc (2013) 2.08
A randomized trial of two methods to disclose prognosis to surrogate decision makers in intensive care units. Am J Respir Crit Care Med (2010) 2.07
A comparison of critical care research funding and the financial burden of critical illness in the United States. Crit Care Med (2012) 2.07
Do hospitals provide lower quality of care to black patients for pneumonia? Crit Care Med (2010) 2.07
Forging a critical alliance: Addressing the research needs of the United States critical illness and injury community. Crit Care Med (2009) 2.03
Use of intensive care services during terminal hospitalizations in England and the United States. Am J Respir Crit Care Med (2009) 2.00
Assessing the feasibility of the American College of Surgeons' benchmarks for the triage of trauma patients. Arch Surg (2011) 1.95
Critical care bed growth in the United States. A comparison of regional and national trends. Am J Respir Crit Care Med (2015) 1.93
A multicenter mortality prediction model for patients receiving prolonged mechanical ventilation. Crit Care Med (2012) 1.92
How does lack of insurance affect use of intensive care? A population-based study. Crit Care Med (2006) 1.92
Temporal changes in management and outcome of septic shock in patients with malignancies in the intensive care unit. Crit Care Med (2008) 1.89
The first international consensus conference on continuous renal replacement therapy. Kidney Int (2002) 1.89
The effects of trauma center care, admission volume, and surgical volume on paralysis after traumatic spinal cord injury. Ann Surg (2009) 1.86
How clinicians discuss critically ill patients' preferences and values with surrogates: an empirical analysis. Crit Care Med (2015) 1.82
Using simulation to isolate physician variation in intensive care unit admission decision making for critically ill elders with end-stage cancer: a pilot feasibility study. Crit Care Med (2008) 1.81
Establishing an evidence base for physician-family communication and shared decision making in the intensive care unit. Crit Care Med (2006) 1.80
Influence of comorbid conditions on long-term mortality after pneumonia in older people. J Am Geriatr Soc (2007) 1.79
An empirical study of surrogates' preferred level of control over value-laden life support decisions in intensive care units. Am J Respir Crit Care Med (2010) 1.79
Physician attitudes toward regionalization of adult critical care: a national survey. Crit Care Med (2009) 1.79
Outcome measures for clinical research in sepsis: a report of the 2nd Cambridge Colloquium of the International Sepsis Forum. Crit Care Med (2005) 1.77
Understanding the potential role of statins in pneumonia and sepsis. Crit Care Med (2011) 1.77
I don't want to be the one saying 'we should just let him die': intrapersonal tensions experienced by surrogate decision makers in the ICU. J Gen Intern Med (2012) 1.76
Variability in management of early severe sepsis. Emerg Med J (2010) 1.76
Racial variation in end-of-life intensive care use: a race or hospital effect? Health Serv Res (2006) 1.76
Development and pilot testing of a decision aid for surrogates of patients with prolonged mechanical ventilation. Crit Care Med (2012) 1.76
Quality of death: assessing the importance placed on end-of-life treatment in the intensive-care unit. Med Care (2004) 1.76
Identifying family members who may struggle in the role of surrogate decision maker. Crit Care Med (2012) 1.75
A randomized trial of the effect of patient race on physicians' intensive care unit and life-sustaining treatment decisions for an acutely unstable elder with end-stage cancer. Crit Care Med (2011) 1.75
Hospital mortality and resource use in subgroups of the Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis (PROWESS) trial. Crit Care Med (2004) 1.73
Surrogate decision makers' interpretation of prognostic information: a mixed-methods study. Ann Intern Med (2012) 1.73
Comparison of Cox and Gray's survival models in severe sepsis. Crit Care Med (2004) 1.72
Differences in immune response may explain lower survival among older men with pneumonia. Crit Care Med (2009) 1.71
Comparison of medical admissions to intensive care units in the United States and United Kingdom. Am J Respir Crit Care Med (2011) 1.69
The lingering consequences of sepsis: a hidden public health disaster? JAMA (2010) 1.67
Informal caregiver burden among survivors of prolonged mechanical ventilation. Am J Respir Crit Care Med (2006) 1.64
Investigating conflict in ICUs-is the clinicians' perspective enough? Crit Care Med (2014) 1.64
Surrogate decision makers' responses to physicians' predictions of medical futility. Chest (2009) 1.64
Access to urban acute care services in high- vs. middle-income countries: an analysis of seven cities. Intensive Care Med (2013) 1.64