Published in Nature on December 20, 2009
Structure of the human mTOR complex I and its implications for rapamycin inhibition. Mol Cell (2010) 3.33
mTOR kinase structure, mechanism and regulation. Nature (2013) 2.80
ATR signalling: more than meeting at the fork. Biochem J (2011) 2.37
Helix unwinding and base flipping enable human MTERF1 to terminate mitochondrial transcription. Cell (2010) 1.93
DNA damage sensing by the ATM and ATR kinases. Cold Spring Harb Perspect Biol (2013) 1.72
A structural model for regulation of NHEJ by DNA-PKcs autophosphorylation. DNA Repair (Amst) (2010) 1.71
DNA double strand break repair via non-homologous end-joining. Transl Cancer Res (2013) 1.61
Repair of double-strand breaks by end joining. Cold Spring Harb Perspect Biol (2013) 1.58
Detection and repair of ionizing radiation-induced DNA double strand breaks: new developments in nonhomologous end joining. Int J Radiat Oncol Biol Phys (2013) 1.57
Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes. Genes Dev (2010) 1.55
XRCC4 protein interactions with XRCC4-like factor (XLF) create an extended grooved scaffold for DNA ligation and double strand break repair. J Biol Chem (2011) 1.48
ATM activation in the presence of oxidative stress. Cell Cycle (2010) 1.40
Structural dynamics in DNA damage signaling and repair. Curr Opin Struct Biol (2010) 1.31
DNA-PK: a dynamic enzyme in a versatile DSB repair pathway. DNA Repair (Amst) (2014) 1.31
Structural characterization of filaments formed by human Xrcc4-Cernunnos/XLF complex involved in nonhomologous DNA end-joining. Proc Natl Acad Sci U S A (2011) 1.18
Choosing the right path: does DNA-PK help make the decision? Mutat Res (2011) 1.18
An unprecedented nucleic acid capture mechanism for excision of DNA damage. Nature (2010) 1.17
EM-fold: de novo atomic-detail protein structure determination from medium-resolution density maps. Structure (2012) 1.15
Rpn1 and Rpn2 coordinate ubiquitin processing factors at proteasome. J Biol Chem (2012) 1.15
Trp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γ and p53 signaling. Nat Chem Biol (2012) 1.15
A method for systematic mapping of protein lysine methylation identifies functions for HP1β in DNA damage response. Mol Cell (2013) 1.14
Human mitochondrial mTERF wraps around DNA through a left-handed superhelical tandem repeat. Nat Struct Mol Biol (2010) 1.12
Nonhomologous end joining: a good solution for bad ends. DNA Repair (Amst) (2014) 1.08
Visualization of a DNA-PK/PARP1 complex. Nucleic Acids Res (2012) 1.08
Chemotherapeutic compounds targeting the DNA double-strand break repair pathways: the good, the bad, and the promising. Front Oncol (2014) 1.06
Nucleic acid recognition by tandem helical repeats. Curr Opin Struct Biol (2011) 1.06
The nonsense-mediated mRNA decay SMG-1 kinase is regulated by large-scale conformational changes controlled by SMG-8. Genes Dev (2011) 1.05
Small Molecules, Inhibitors of DNA-PK, Targeting DNA Repair, and Beyond. Front Pharmacol (2013) 1.05
Structural insights into NHEJ: building up an integrated picture of the dynamic DSB repair super complex, one component and interaction at a time. DNA Repair (Amst) (2014) 1.03
BCL::Fold--de novo prediction of complex and large protein topologies by assembly of secondary structure elements. PLoS One (2012) 1.00
The spatial organization of non-homologous end joining: from bridging to end joining. DNA Repair (Amst) (2014) 0.99
The N-terminal region of the DNA-dependent protein kinase catalytic subunit is required for its DNA double-stranded break-mediated activation. J Biol Chem (2013) 0.97
The DNA-dependent protein kinase: A multifunctional protein kinase with roles in DNA double strand break repair and mitosis. Prog Biophys Mol Biol (2014) 0.96
One small step for Mot1; one giant leap for other Swi2/Snf2 enzymes? Biochim Biophys Acta (2011) 0.93
Coordination of DNA-PK activation and nuclease processing of DNA termini in NHEJ. Antioxid Redox Signal (2010) 0.90
Targeting nonhomologous end-joining through epidermal growth factor receptor inhibition: rationale and strategies for radiosensitization. Semin Radiat Oncol (2010) 0.90
All stressed out without ATM kinase. Sci Signal (2011) 0.87
Unraveling the complexities of DNA-dependent protein kinase autophosphorylation. Mol Cell Biol (2014) 0.87
Structural mechanisms underlying signaling in the cellular response to DNA double strand breaks. Mutat Res (2013) 0.86
The enterococcal cytolysin synthetase has an unanticipated lipid kinase fold. Elife (2015) 0.86
The DNA damage response kinases DNA-dependent protein kinase (DNA-PK) and ataxia telangiectasia mutated (ATM) Are stimulated by bulky adduct-containing DNA. J Biol Chem (2011) 0.86
Requirement of the FATC domain of protein kinase Tel1 for localization to DNA ends and target protein recognition. Mol Biol Cell (2015) 0.85
Evidence for a remodelling of DNA-PK upon autophosphorylation from electron microscopy studies. Nucleic Acids Res (2011) 0.85
Non-homologous DNA end joining and alternative pathways to double-strand break repair. Nat Rev Mol Cell Biol (2017) 0.85
DNA repair targeted therapy: The past or future of cancer treatment? Pharmacol Ther (2016) 0.84
Structural biology of DNA repair: spatial organisation of the multicomponent complexes of nonhomologous end joining. J Nucleic Acids (2010) 0.84
N-terminal constraint activates the catalytic subunit of the DNA-dependent protein kinase in the absence of DNA or Ku. Nucleic Acids Res (2011) 0.84
Hitting the brakes: termination of mitochondrial transcription. Biochim Biophys Acta (2011) 0.84
Genome-wide identification, evolution and expression analysis of mTERF gene family in maize. PLoS One (2014) 0.84
Ionizing radiation-induced DNA injury and damage detection in patients with breast cancer. Genet Mol Biol (2015) 0.84
Tor forms a dimer through an N-terminal helical solenoid with a complex topology. Nat Commun (2016) 0.83
A network of SMG-8, SMG-9 and SMG-1 C-terminal insertion domain regulates UPF1 substrate recruitment and phosphorylation. Nucleic Acids Res (2015) 0.83
Analysis of mutations that dissociate G(2) and essential S phase functions of human ataxia telangiectasia-mutated and Rad3-related (ATR) protein kinase. J Biol Chem (2011) 0.82
Kinase activity profiling of pneumococcal pneumonia. PLoS One (2011) 0.81
Two-Stage Synapsis of DNA Ends during Non-homologous End Joining. Mol Cell (2016) 0.81
Genetic evidence links the ASTRA protein chaperone component Tti2 to the SAGA transcription factor Tra1. Genetics (2012) 0.79
Structure of the intact ATM/Tel1 kinase. Nat Commun (2016) 0.79
An Intrinsically Disordered APLF Links Ku, DNA-PKcs and XRCC4-DNA Ligase IV in an Extended Flexible Non-Homologous End Joining Complex. J Biol Chem (2016) 0.78
Coincident In Vitro Analysis of DNA-PK-Dependent and -Independent Nonhomologous End Joining. J Nucleic Acids (2010) 0.78
Conformational flexibility and subunit arrangement of the modular yeast Spt-Ada-Gcn5 acetyltransferase complex. J Biol Chem (2015) 0.78
Crystal structure of Cex1p reveals the mechanism of tRNA trafficking between nucleus and cytoplasm. Nucleic Acids Res (2013) 0.78
The C-terminal residues of Saccharomyces cerevisiae Mec1 are required for its localization, stability, and function. G3 (Bethesda) (2013) 0.77
Non-canonical Bromodomain within DNA-PKcs Promotes DNA Damage Response and Radioresistance through Recognizing an IR-Induced Acetyl-Lysine on H2AX. Chem Biol (2015) 0.77
Prospects for the Use of ATR Inhibitors to Treat Cancer. Pharmaceuticals (Basel) (2010) 0.77
Structure of the human dimeric ATM kinase. Cell Cycle (2016) 0.77
Recognition of DNA Termini by the C-Terminal Region of the Ku80 and the DNA-Dependent Protein Kinase Catalytic Subunit. PLoS One (2015) 0.76
The Dimeric Architecture of Checkpoint Kinases Mec1ATR and Tel1ATM Reveal a Common Structural Organization. J Biol Chem (2016) 0.76
Loss of nonsense mediated decay suppresses mutations in Saccharomyces cerevisiae TRA1. BMC Genet (2012) 0.76
The RNA helicase DHX34 functions as a scaffold for SMG1-mediated UPF1 phosphorylation. Nat Commun (2016) 0.76
Mutation of serine 1333 in the ATR HEAT repeats creates a hyperactive kinase. PLoS One (2014) 0.76
Reversion of the ErbB malignant phenotype and the DNA damage response. Exp Mol Pathol (2012) 0.76
New diagnosis of atypical ataxia-telangiectasia in a 17-year-old boy with T-cell acute lymphoblastic leukemia and a novel ATM mutation. J Hum Genet (2017) 0.75
ATR-mediated regulation of nuclear and cellular plasticity. DNA Repair (Amst) (2016) 0.75
Lysines 3241 and 3260 of DNA-PKcs are important for genomic stability and radioresistance. Biochem Biophys Res Commun (2016) 0.75
Dynamic structures in DNA damage responses & cancer. Prog Biophys Mol Biol (2015) 0.75
Computational determination of the orientation of a heat repeat-like domain of DNA-PKcs. Comput Biol Chem (2012) 0.75
Crystallization and preliminary analysis of crystals of the 24-meric hemocyanin of the emperor scorpion (Pandinus imperator). PLoS One (2012) 0.75
Interaction between HIV-1 Tat and DNA-PKcs modulates HIV transcription and class switch recombination. Int J Biol Sci (2014) 0.75
What Combined Measurements From Structures and Imaging Tell Us About DNA Damage Responses. Methods Enzymol (2017) 0.75
Coot: model-building tools for molecular graphics. Acta Crystallogr D Biol Crystallogr (2004) 227.01
The CCP4 suite: programs for protein crystallography. Acta Crystallogr D Biol Crystallogr (1994) 187.88
Refinement of macromolecular structures by the maximum-likelihood method. Acta Crystallogr D Biol Crystallogr (1997) 137.43
PHENIX: building new software for automated crystallographic structure determination. Acta Crystallogr D Biol Crystallogr (2002) 53.61
Use of non-crystallographic symmetry in protein structure refinement. Acta Crystallogr D Biol Crystallogr (1996) 8.03
Generation, representation and flow of phase information in structure determination: recent developments in and around SHARP 2.0. Acta Crystallogr D Biol Crystallogr (2003) 7.82
The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen. Cell (1993) 7.17
Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination. Cell (2002) 6.34
DNA end-joining: from yeast to man. Trends Biochem Sci (1998) 4.94
DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product. Cell (1995) 4.64
Structure of importin-beta bound to the IBB domain of importin-alpha. Nature (1999) 4.05
Structural insights into phosphoinositide 3-kinase catalysis and signalling. Nature (1999) 3.81
scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair. Proc Natl Acad Sci U S A (1991) 3.69
Structure of the Cand1-Cul1-Roc1 complex reveals regulatory mechanisms for the assembly of the multisubunit cullin-dependent ubiquitin ligases. Cell (2004) 3.07
A DNA-activated protein kinase from HeLa cell nuclei. Mol Cell Biol (1990) 2.95
The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs. Cell (1999) 2.89
Interaction of DNA-dependent protein kinase with DNA and with Ku: biochemical and atomic-force microscopy studies. EMBO J (1997) 2.78
Three-dimensional structure of the human DNA-PKcs/Ku70/Ku80 complex assembled on DNA and its implications for DNA DSB repair. Mol Cell (2006) 2.43
Cryo-EM structure of the DNA-dependent protein kinase catalytic subunit at subnanometer resolution reveals alpha helices and insight into DNA binding. Structure (2008) 2.17
X-ray sensitive mutants of Chinese hamster ovary cells defective in double-strand break rejoining. Mutat Res (1985) 2.10
Purification and characterization of a template-associated protein kinase that phosphorylates RNA polymerase II. J Biol Chem (1993) 2.08
Geometry of a complex formed by double strand break repair proteins at a single DNA end: recruitment of DNA-PKcs induces inward translocation of Ku protein. Nucleic Acids Res (1999) 1.96
FAT: a novel domain in PIK-related kinases. Trends Biochem Sci (2000) 1.96
Responses to DNA damage and regulation of cell cycle checkpoints by the ATM protein kinase family. Curr Opin Genet Dev (1997) 1.94
trans Autophosphorylation at DNA-dependent protein kinase's two major autophosphorylation site clusters facilitates end processing but not end joining. Mol Cell Biol (2007) 1.80
DNA damage and the DNA-activated protein kinase. Trends Biochem Sci (1993) 1.79
Solution structure of the C-terminal domain of Ku80 suggests important sites for protein-protein interactions. Structure (2004) 1.78
Mapping of protein-protein interactions within the DNA-dependent protein kinase complex. Nucleic Acids Res (1999) 1.72
Three-dimensional structure and regulation of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs). Structure (2005) 1.62
Structure of DNA-dependent protein kinase: implications for its regulation by DNA. EMBO J (1999) 1.54
The solution structure of the FATC domain of the protein kinase target of rapamycin suggests a role for redox-dependent structural and cellular stability. J Biol Chem (2005) 1.49
Visualization of DNA-induced conformational changes in the DNA repair kinase DNA-PKcs. EMBO J (2003) 1.32
Characterization of an X-ray-hypersensitive mutant of V79 Chinese hamster cells. Mutat Res (1988) 1.25
Cryo-EM imaging of the catalytic subunit of the DNA-dependent protein kinase. J Mol Biol (1998) 1.21
The 3D solution structure of the C-terminal region of Ku86 (Ku86CTR). J Mol Biol (2004) 1.14
Ta6Br14 is a useful cluster compound for isomorphous replacement in protein crystallography. Acta Crystallogr D Biol Crystallogr (1994) 0.82
Insights into DNA recombination from the structure of a RAD51-BRCA2 complex. Nature (2002) 4.22
Heterogeneity and inaccuracy in protein structures solved by X-ray crystallography. Structure (2004) 3.32
Full-length archaeal Rad51 structure and mutants: mechanisms for RAD51 assembly and control by BRCA2. EMBO J (2003) 2.95
Is one solution good enough? Nat Struct Mol Biol (2006) 2.91
Tumor risks and genotype-phenotype-proteotype analysis in 358 patients with germline mutations in SDHB and SDHD. Hum Mutat (2010) 2.75
Knowledge-based real-space explorations for low-resolution structure determination. Structure (2006) 2.52
Crystallographic refinement by knowledge-based exploration of complex energy landscapes. Structure (2005) 2.42
Analysis of the thyrotropin receptor-thyrotropin interaction by comparative modeling. Thyroid (2004) 2.28
SDM--a server for predicting effects of mutations on protein stability and malfunction. Nucleic Acids Res (2011) 2.28
BUB1 and BUBR1: multifaceted kinases of the cell cycle. Trends Biochem Sci (2010) 1.99
Structural basis of hepatocyte growth factor/scatter factor and MET signalling. Proc Natl Acad Sci U S A (2006) 1.85
Sequence fingerprints in BRCA2 and RAD51: implications for DNA repair and cancer. DNA Repair (Amst) (2003) 1.72
pyDock: electrostatics and desolvation for effective scoring of rigid-body protein-protein docking. Proteins (2007) 1.69
mCSM: predicting the effects of mutations in proteins using graph-based signatures. Bioinformatics (2013) 1.69
Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ. EMBO J (2007) 1.66
Atomic interactions and profile of small molecules disrupting protein-protein interfaces: the TIMBAL database. Chem Biol Drug Des (2009) 1.64
Crystal structure of the TSH receptor in complex with a thyroid-stimulating autoantibody. Thyroid (2007) 1.64
Genome3D: a UK collaborative project to annotate genomic sequences with predicted 3D structures based on SCOP and CATH domains. Nucleic Acids Res (2012) 1.63
Structural biology and drug discovery. Drug Discov Today (2005) 1.59
A novel type of deubiquitinating enzyme. J Biol Chem (2003) 1.57
Chimeric glycosyltransferases for the generation of hybrid glycopeptides. Chem Biol (2009) 1.57
The crystal structure of fibroblast growth factor (FGF) 19 reveals novel features of the FGF family and offers a structural basis for its unusual receptor affinity. Biochemistry (2004) 1.57
Ab initio construction of polypeptide fragments: efficient generation of accurate, representative ensembles. Proteins (2003) 1.56
Distinguishing structural and functional restraints in evolution in order to identify interaction sites. J Mol Biol (2004) 1.52
Functional map and domain structure of MET, the product of the c-met protooncogene and receptor for hepatocyte growth factor/scatter factor. Proc Natl Acad Sci U S A (2003) 1.42
Structural biology in fragment-based drug design. Curr Opin Struct Biol (2010) 1.36
Structural and functional constraints in the evolution of protein families. Nat Rev Mol Cell Biol (2009) 1.35
Dynamic control of Rad51 recombinase by self-association and interaction with BRCA2. Mol Cell (2003) 1.33
Probing hot spots at protein-ligand binding sites: a fragment-based approach using biophysical methods. J Med Chem (2006) 1.31
On the origins of enzyme inhibitor selectivity and promiscuity: a case study of protein kinase binding to staurosporine. Chem Biol Drug Des (2009) 1.30
Crystal structure of folliculin reveals a hidDENN function in genetically inherited renal cancer. Open Biol (2012) 1.29
Structural biology and drug discovery of difficult targets: the limits of ligandability. Chem Biol (2012) 1.27
A structural bioinformatics approach to the analysis of nonsynonymous single nucleotide polymorphisms (nsSNPs) and their relation to disease. J Bioinform Comput Biol (2007) 1.26
Nanostructured films from hierarchical self-assembly of amyloidogenic proteins. Nat Nanotechnol (2010) 1.19
Evidence that heparin saccharides promote FGF2 mitogenesis through two distinct mechanisms. J Biol Chem (2008) 1.19
Structural constraints on protein self-processing in L-aspartate-alpha-decarboxylase. EMBO J (2003) 1.19
Application of fragment growing and fragment linking to the discovery of inhibitors of Mycobacterium tuberculosis pantothenate synthetase. Angew Chem Int Ed Engl (2009) 1.19
Andante: reducing side-chain rotamer search space during comparative modeling using environment-specific substitution probabilities. Bioinformatics (2007) 1.18
Structure of an Xrcc4-DNA ligase IV yeast ortholog complex reveals a novel BRCT interaction mode. DNA Repair (Amst) (2006) 1.18
Prediction by graph theoretic measures of structural effects in proteins arising from non-synonymous single nucleotide polymorphisms. PLoS Comput Biol (2008) 1.16
Conformer generation under restraints. Curr Opin Struct Biol (2006) 1.16
Structural biology and drug discovery for protein-protein interactions. Trends Pharmacol Sci (2012) 1.15
Towards a resolution of the stoichiometry of the fibroblast growth factor (FGF)-FGF receptor-heparin complex. J Mol Biol (2004) 1.14
Functional specificity of the Xenopus T-domain protein Brachyury is conferred by its ability to interact with Smad1. Dev Cell (2005) 1.13
An algorithm for predicting protein-protein interaction sites: Abnormally exposed amino acid residues and secondary structure elements. Protein Sci (2006) 1.12
Cockroach allergen Bla g 2: structure, function, and implications for allergic sensitization. Am J Respir Crit Care Med (2002) 1.11
BIPA: a database for protein-nucleic acid interaction in 3D structures. Bioinformatics (2009) 1.10
Biophysical and computational fragment-based approaches to targeting protein-protein interactions: applications in structure-guided drug discovery. Q Rev Biophys (2012) 1.09
Using a fragment-based approach to target protein-protein interactions. Chembiochem (2013) 1.09
Cooperative dimerization of fibroblast growth factor 1 (FGF1) upon a single heparin saccharide may drive the formation of 2:2:1 FGF1.FGFR2c.heparin ternary complexes. J Biol Chem (2005) 1.08
Defining the molecular basis of BubR1 kinetochore interactions and APC/C-CDC20 inhibition. J Biol Chem (2010) 1.08
High-resolution crystal structure of the human Notch 1 ankyrin domain. Biochem J (2005) 1.06
The crystal structure of the N-terminal region of BUB1 provides insight into the mechanism of BUB1 recruitment to kinetochores. Structure (2009) 1.05
Ulla: a program for calculating environment-specific amino acid substitution tables. Bioinformatics (2009) 1.05
Inhibition of Mycobacterium tuberculosis pantothenate synthetase by analogues of the reaction intermediate. Chembiochem (2008) 1.05
Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure (2011) 1.04
Crystal structure of rat liver betaine homocysteine s-methyltransferase reveals new oligomerization features and conformational changes upon substrate binding. J Mol Biol (2004) 1.03
Non-homologous end-joining partners in a helical dance: structural studies of XLF-XRCC4 interactions. Biochem Soc Trans (2011) 1.02
Advantages of fine-grained side chain conformer libraries. Protein Eng (2003) 1.01
Identifying interaction motifs in CK2beta--a ubiquitous kinase regulatory subunit. Trends Biochem Sci (2006) 1.00
Structural bioinformatics mutation analysis reveals genotype-phenotype correlations in von Hippel-Lindau disease and suggests molecular mechanisms of tumorigenesis. Proteins (2009) 1.00
Multimers of the fibroblast growth factor (FGF)-FGF receptor-saccharide complex are formed on long oligomers of heparin. Biochem J (2006) 1.00
Cell biology: brief encounters bolster contacts. Nature (2006) 1.00
Coupling growth-factor engineering with nanotechnology for therapeutic angiogenesis. Proc Natl Acad Sci U S A (2010) 0.99
Comprehensive, atomic-level characterization of structurally characterized protein-protein interactions: the PICCOLO database. BMC Bioinformatics (2011) 0.97
Characterization of spindle checkpoint kinase Mps1 reveals domain with functional and structural similarities to tetratricopeptide repeat motifs of Bub1 and BubR1 checkpoint kinases. J Biol Chem (2011) 0.97
Model-building strategies for low-resolution X-ray crystallographic data. Acta Crystallogr D Biol Crystallogr (2009) 0.96
Structural enzymology of Li(+)-sensitive/Mg(2+)-dependent phosphatases. J Mol Biol (2002) 0.95
Genome bioinformatic analysis of nonsynonymous SNPs. BMC Bioinformatics (2007) 0.95
Organisation of the pantothenate (vitamin B5) biosynthesis pathway in higher plants. Plant J (2004) 0.94
Protein-protein interactions as druggable targets: recent technological advances. Curr Opin Pharmacol (2013) 0.94
Crystal structures of Yersinia enterocolitica salicylate synthase and its complex with the reaction products salicylate and pyruvate. J Mol Biol (2006) 0.93
Structural and functional restraints on the occurrence of single amino acid variations in human proteins. PLoS One (2010) 0.93
Satisfaction of hydrogen-bonding potential influences the conservation of polar sidechains. Proteins (2009) 0.93
Structural and functional restraints in the evolution of protein families and superfamilies. Biochem Soc Trans (2009) 0.93
Discarding functional residues from the substitution table improves predictions of active sites within three-dimensional structures. PLoS Comput Biol (2008) 0.93
Structural insights into the role of domain flexibility in human DNA ligase IV. Structure (2012) 0.92
Does a more precise chemical description of protein-ligand complexes lead to more accurate prediction of binding affinity? J Chem Inf Model (2014) 0.92
1.15 A crystal structure of the X. tropicalis Spred1 EVH1 domain suggests a fourth distinct peptide-binding mechanism within the EVH1 family. FEBS Lett (2005) 0.91
Expanding the solvent chemical space for self-assembly of dipeptide nanostructures. ACS Nano (2014) 0.91
Molecular dissection of the interaction between the small G proteins Rac1 and RhoA and protein kinase C-related kinase 1 (PRK1). J Biol Chem (2003) 0.91
Molecular mechanism of SSR128129E, an extracellularly acting, small-molecule, allosteric inhibitor of FGF receptor signaling. Cancer Cell (2013) 0.91
Optimization of the interligand Overhauser effect for fragment linking: application to inhibitor discovery against Mycobacterium tuberculosis pantothenate synthetase. J Am Chem Soc (2010) 0.91
Structural and functional insights into the role of the N-terminal Mps1 TPR domain in the SAC (spindle assembly checkpoint). Biochem J (2012) 0.91