| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Heart disease and stroke statistics--2012 update: a report from the American Heart Association.
|
Circulation
|
2011
|
31.98
|
|
2
|
Heart disease and stroke statistics--2013 update: a report from the American Heart Association.
|
Circulation
|
2012
|
30.79
|
|
3
|
Heart disease and stroke statistics--2011 update: a report from the American Heart Association.
|
Circulation
|
2010
|
30.07
|
|
4
|
Heart disease and stroke statistics--2014 update: a report from the American Heart Association.
|
Circulation
|
2013
|
28.02
|
|
5
|
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
|
Nat Genet
|
2010
|
23.08
|
|
6
|
Hundreds of variants clustered in genomic loci and biological pathways affect human height.
|
Nature
|
2010
|
20.01
|
|
7
|
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.
|
Nat Genet
|
2010
|
17.89
|
|
8
|
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.
|
Nat Genet
|
2010
|
16.96
|
|
9
|
Metabolite profiles and the risk of developing diabetes.
|
Nat Med
|
2011
|
12.22
|
|
10
|
Genome-wide association study of blood pressure and hypertension.
|
Nat Genet
|
2009
|
11.54
|
|
11
|
Variants in MTNR1B influence fasting glucose levels.
|
Nat Genet
|
2008
|
10.85
|
|
12
|
The Third Generation Cohort of the National Heart, Lung, and Blood Institute's Framingham Heart Study: design, recruitment, and initial examination.
|
Am J Epidemiol
|
2007
|
9.90
|
|
13
|
Genotype score in addition to common risk factors for prediction of type 2 diabetes.
|
N Engl J Med
|
2008
|
9.68
|
|
14
|
Prediction of incident diabetes mellitus in middle-aged adults: the Framingham Offspring Study.
|
Arch Intern Med
|
2007
|
8.59
|
|
15
|
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
|
Nat Genet
|
2010
|
7.94
|
|
16
|
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.
|
Nat Genet
|
2010
|
6.66
|
|
17
|
Executive summary: heart disease and stroke statistics--2014 update: a report from the American Heart Association.
|
Circulation
|
2014
|
6.55
|
|
18
|
Soft drink consumption and risk of developing cardiometabolic risk factors and the metabolic syndrome in middle-aged adults in the community.
|
Circulation
|
2007
|
6.34
|
|
19
|
Relations of serum phosphorus and calcium levels to the incidence of cardiovascular disease in the community.
|
Arch Intern Med
|
2007
|
6.29
|
|
20
|
Executive summary: heart disease and stroke statistics--2012 update: a report from the American Heart Association.
|
Circulation
|
2012
|
6.24
|
|
21
|
Executive summary: heart disease and stroke statistics--2013 update: a report from the American Heart Association.
|
Circulation
|
2013
|
6.13
|
|
22
|
Pericardial fat, visceral abdominal fat, cardiovascular disease risk factors, and vascular calcification in a community-based sample: the Framingham Heart Study.
|
Circulation
|
2008
|
5.95
|
|
23
|
Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study.
|
Lancet
|
2008
|
5.89
|
|
24
|
New loci associated with kidney function and chronic kidney disease.
|
Nat Genet
|
2010
|
5.58
|
|
25
|
Loss-of-function mutations in APOC3, triglycerides, and coronary disease.
|
N Engl J Med
|
2014
|
5.47
|
|
26
|
Body mass index, metabolic syndrome, and risk of type 2 diabetes or cardiovascular disease.
|
J Clin Endocrinol Metab
|
2006
|
5.33
|
|
27
|
Visceral and subcutaneous adipose tissue volumes are cross-sectionally related to markers of inflammation and oxidative stress: the Framingham Heart Study.
|
Circulation
|
2007
|
5.10
|
|
28
|
The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports.
|
BMC Med Genet
|
2007
|
5.02
|
|
29
|
Association of smoking cessation and weight change with cardiovascular disease among adults with and without diabetes.
|
JAMA
|
2013
|
4.81
|
|
30
|
Multiple loci associated with indices of renal function and chronic kidney disease.
|
Nat Genet
|
2009
|
4.78
|
|
31
|
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.
|
Nat Genet
|
2012
|
4.37
|
|
32
|
Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.
|
Nat Genet
|
2009
|
4.28
|
|
33
|
Low-grade albuminuria and incidence of cardiovascular disease events in nonhypertensive and nondiabetic individuals: the Framingham Heart Study.
|
Circulation
|
2005
|
4.08
|
|
34
|
Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways.
|
Diabetes
|
2010
|
4.07
|
|
35
|
Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits.
|
PLoS Genet
|
2011
|
3.92
|
|
36
|
Fatty liver is associated with dyslipidemia and dysglycemia independent of visceral fat: the Framingham Heart Study.
|
Hepatology
|
2010
|
3.60
|
|
37
|
Association of pericardial fat, intrathoracic fat, and visceral abdominal fat with cardiovascular disease burden: the Framingham Heart Study.
|
Eur Heart J
|
2009
|
3.54
|
|
38
|
Gamma glutamyl transferase and metabolic syndrome, cardiovascular disease, and mortality risk: the Framingham Heart Study.
|
Arterioscler Thromb Vasc Biol
|
2006
|
3.48
|
|
39
|
Neck circumference as a novel measure of cardiometabolic risk: the Framingham Heart study.
|
J Clin Endocrinol Metab
|
2010
|
3.39
|
|
40
|
Effect of aging on A1C levels in individuals without diabetes: evidence from the Framingham Offspring Study and the National Health and Nutrition Examination Survey 2001-2004.
|
Diabetes Care
|
2008
|
3.33
|
|
41
|
On the replication of genetic associations: timing can be everything!
|
Am J Hum Genet
|
2008
|
3.32
|
|
42
|
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
|
Nat Genet
|
2013
|
3.25
|
|
43
|
Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes.
|
Hum Mol Genet
|
2010
|
3.24
|
|
44
|
Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans.
|
J Clin Invest
|
2011
|
3.23
|
|
45
|
Trends in all-cause and cardiovascular disease mortality among women and men with and without diabetes mellitus in the Framingham Heart Study, 1950 to 2005.
|
Circulation
|
2009
|
3.23
|
|
46
|
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.
|
PLoS Genet
|
2012
|
3.21
|
|
47
|
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.
|
Nat Genet
|
2011
|
3.18
|
|
48
|
NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium.
|
PLoS Genet
|
2009
|
3.18
|
|
49
|
Visceral fat is associated with lower brain volume in healthy middle-aged adults.
|
Ann Neurol
|
2010
|
3.05
|
|
50
|
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.
|
Nat Genet
|
2012
|
3.04
|
|
51
|
Framingham Heart Study 100K project: genome-wide associations for cardiovascular disease outcomes.
|
BMC Med Genet
|
2007
|
2.93
|
|
52
|
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits.
|
PLoS Genet
|
2013
|
2.83
|
|
53
|
Abdominal subcutaneous adipose tissue: a protective fat depot?
|
Diabetes Care
|
2009
|
2.80
|
|
54
|
FTO genotype is associated with phenotypic variability of body mass index.
|
Nature
|
2012
|
2.77
|
|
55
|
Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors.
|
Circ Cardiovasc Genet
|
2010
|
2.76
|
|
56
|
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile.
|
Nat Genet
|
2011
|
2.73
|
|
57
|
Aminotransferase levels and 20-year risk of metabolic syndrome, diabetes, and cardiovascular disease.
|
Gastroenterology
|
2008
|
2.70
|
|
58
|
CUBN is a gene locus for albuminuria.
|
J Am Soc Nephrol
|
2011
|
2.70
|
|
59
|
Adiposity, cardiometabolic risk, and vitamin D status: the Framingham Heart Study.
|
Diabetes
|
2009
|
2.70
|
|
60
|
Statin use and sepsis events [corrected] in patients with chronic kidney disease.
|
JAMA
|
2007
|
2.69
|
|
61
|
Impact of impaired fasting glucose on cardiovascular disease: the Framingham Heart Study.
|
J Am Coll Cardiol
|
2008
|
2.64
|
|
62
|
Long-term trends in myocardial infarction incidence and case fatality in the National Heart, Lung, and Blood Institute's Framingham Heart study.
|
Circulation
|
2009
|
2.63
|
|
63
|
A 100K genome-wide association scan for diabetes and related traits in the Framingham Heart Study: replication and integration with other genome-wide datasets.
|
Diabetes
|
2007
|
2.60
|
|
64
|
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.
|
Am J Hum Genet
|
2012
|
2.53
|
|
65
|
Metabolite profiling identifies pathways associated with metabolic risk in humans.
|
Circulation
|
2012
|
2.51
|
|
66
|
Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans.
|
Diabetes
|
2010
|
2.44
|
|
67
|
Abdominal subcutaneous and visceral adipose tissue and insulin resistance in the Framingham heart study.
|
Obesity (Silver Spring)
|
2010
|
2.42
|
|
68
|
Impact of A1C screening criterion on the diagnosis of pre-diabetes among U.S. adults.
|
Diabetes Care
|
2010
|
2.38
|
|
69
|
Impact of abdominal visceral and subcutaneous adipose tissue on cardiometabolic risk factors: the Jackson Heart Study.
|
J Clin Endocrinol Metab
|
2010
|
2.37
|
|
70
|
The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts.
|
PLoS Genet
|
2007
|
2.35
|
|
71
|
Cardiovascular disease risk factors in chronic kidney disease: overall burden and rates of treatment and control.
|
Arch Intern Med
|
2006
|
2.28
|
|
72
|
Defining normal distributions of coronary artery calcium in women and men (from the Framingham Heart Study).
|
Am J Cardiol
|
2008
|
2.26
|
|
73
|
Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes.
|
Diabetes
|
2011
|
2.21
|
|
74
|
Analyze multivariate phenotypes in genetic association studies by combining univariate association tests.
|
Genet Epidemiol
|
2010
|
2.19
|
|
75
|
Visceral and subcutaneous fat quality and cardiometabolic risk.
|
JACC Cardiovasc Imaging
|
2013
|
2.19
|
|
76
|
High prevalence of peripheral arterial disease in persons with renal insufficiency: results from the National Health and Nutrition Examination Survey 1999-2000.
|
Circulation
|
2004
|
2.17
|
|
77
|
2-Aminoadipic acid is a biomarker for diabetes risk.
|
J Clin Invest
|
2013
|
2.15
|
|
78
|
Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height.
|
Am J Hum Genet
|
2010
|
2.15
|
|
79
|
Fatty kidney, hypertension, and chronic kidney disease: the Framingham Heart Study.
|
Hypertension
|
2011
|
2.13
|
|
80
|
Uromodulin levels associate with a common UMOD variant and risk for incident CKD.
|
J Am Soc Nephrol
|
2009
|
2.10
|
|
81
|
Low-grade albuminuria and the risks of hypertension and blood pressure progression.
|
Circulation
|
2005
|
2.09
|
|
82
|
Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide polymorphisms.
|
Diabetes Care
|
2010
|
2.06
|
|
83
|
Associations of adiponectin, resistin, and tumor necrosis factor-alpha with insulin resistance.
|
J Clin Endocrinol Metab
|
2008
|
2.03
|
|
84
|
Genome-wide association study for subclinical atherosclerosis in major arterial territories in the NHLBI's Framingham Heart Study.
|
BMC Med Genet
|
2007
|
2.00
|
|
85
|
Body fat distribution, incident cardiovascular disease, cancer, and all-cause mortality.
|
J Am Coll Cardiol
|
2013
|
1.96
|
|
86
|
Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction.
|
Circulation
|
2011
|
1.96
|
|
87
|
Biomarkers of the osteoprotegerin pathway: clinical correlates, subclinical disease, incident cardiovascular disease, and mortality.
|
Arterioscler Thromb Vasc Biol
|
2010
|
1.95
|
|
88
|
Increasing trends in incidence of overweight and obesity over 5 decades.
|
Am J Med
|
2007
|
1.95
|
|
89
|
Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque.
|
Nat Genet
|
2011
|
1.92
|
|
90
|
Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six Loci influencing serum magnesium levels.
|
PLoS Genet
|
2010
|
1.91
|
|
91
|
Lower urinary connective tissue growth factor levels and incident CKD stage 3 in the general population.
|
Am J Kidney Dis
|
2011
|
1.88
|
|
92
|
Genome-wide search for genes affecting serum uric acid levels: the Framingham Heart Study.
|
Metabolism
|
2005
|
1.88
|
|
93
|
Overweight, obesity, and the development of stage 3 CKD: the Framingham Heart Study.
|
Am J Kidney Dis
|
2008
|
1.82
|
|
94
|
Cross-classification of microalbuminuria and reduced glomerular filtration rate: associations between cardiovascular disease risk factors and clinical outcomes.
|
Arch Intern Med
|
2007
|
1.81
|
|
95
|
A genetic risk score is associated with incident cardiovascular disease and coronary artery calcium: the Framingham Heart Study.
|
Circ Cardiovasc Genet
|
2012
|
1.81
|
|
96
|
Common variants in the adiponectin gene (ADIPOQ) associated with plasma adiponectin levels, type 2 diabetes, and diabetes-related quantitative traits: the Framingham Offspring Study.
|
Diabetes
|
2008
|
1.80
|
|
97
|
Trends in cardiovascular disease risk factors in individuals with and without diabetes mellitus in the Framingham Heart Study.
|
Circulation
|
2009
|
1.77
|
|
98
|
Pericardial adipose tissue, atherosclerosis, and cardiovascular disease risk factors: the Jackson heart study.
|
Diabetes Care
|
2010
|
1.77
|
|
99
|
Ectopic fat depots and cardiovascular disease.
|
Circulation
|
2011
|
1.77
|
|
100
|
Parental occurrence of premature cardiovascular disease predicts increased coronary artery and abdominal aortic calcification in the Framingham Offspring and Third Generation cohorts.
|
Circulation
|
2007
|
1.75
|
|
101
|
Relations of insulin sensitivity to longitudinal blood pressure tracking: variations with baseline age, body mass index, and blood pressure.
|
Circulation
|
2005
|
1.75
|
|
102
|
Metabolic syndrome, insulin resistance, and brachial artery vasodilator function in Framingham Offspring participants without clinical evidence of cardiovascular disease.
|
Am J Cardiol
|
2008
|
1.74
|
|
103
|
Volumetric measurement of pericardial adipose tissue from contrast-enhanced coronary computed tomography angiography: a reproducibility study.
|
J Cardiovasc Comput Tomogr
|
2008
|
1.73
|
|
104
|
A genome-wide association search for type 2 diabetes genes in African Americans.
|
PLoS One
|
2012
|
1.72
|
|
105
|
TCF7L2 variants associate with CKD progression and renal function in population-based cohorts.
|
J Am Soc Nephrol
|
2008
|
1.71
|
|
106
|
Biomarkers of cardiovascular stress and incident chronic kidney disease.
|
Clin Chem
|
2013
|
1.71
|
|
107
|
The MYH9/APOL1 region and chronic kidney disease in European-Americans.
|
Hum Mol Genet
|
2011
|
1.71
|
|
108
|
Pericardial fat is associated with prevalent atrial fibrillation: the Framingham Heart Study.
|
Circ Arrhythm Electrophysiol
|
2010
|
1.70
|
|
109
|
Use of alternative thresholds defining insulin resistance to predict incident type 2 diabetes mellitus and cardiovascular disease.
|
Circulation
|
2008
|
1.68
|
|
110
|
Genome-wide association and functional follow-up reveals new loci for kidney function.
|
PLoS Genet
|
2012
|
1.68
|
|
111
|
Association of eGFR-Related Loci Identified by GWAS with Incident CKD and ESRD.
|
PLoS Genet
|
2011
|
1.68
|
|
112
|
The impact of reclassifying moderate CKD as a coronary heart disease risk equivalent on the number of US adults recommended lipid-lowering treatment.
|
Am J Kidney Dis
|
2007
|
1.67
|
|
113
|
Association of metabolic dysregulation with volumetric brain magnetic resonance imaging and cognitive markers of subclinical brain aging in middle-aged adults: the Framingham Offspring Study.
|
Diabetes Care
|
2011
|
1.66
|
|
114
|
Relation of visceral adiposity to circulating natriuretic peptides in ambulatory individuals.
|
Am J Cardiol
|
2011
|
1.65
|
|
115
|
Multimarker approach to evaluate the incidence of the metabolic syndrome and longitudinal changes in metabolic risk factors: the Framingham Offspring Study.
|
Circulation
|
2007
|
1.65
|
|
116
|
Multiple loci are associated with white blood cell phenotypes.
|
PLoS Genet
|
2011
|
1.65
|
|
117
|
Liver fat is reproducibly measured using computed tomography in the Framingham Heart Study.
|
J Gastroenterol Hepatol
|
2008
|
1.62
|
|
118
|
Genetics of the Framingham Heart Study population.
|
Adv Genet
|
2008
|
1.62
|
|
119
|
Patterns of abdominal fat distribution: the Framingham Heart Study.
|
Diabetes Care
|
2008
|
1.62
|
|
120
|
Impact of insulin resistance on risk of type 2 diabetes and cardiovascular disease in people with metabolic syndrome.
|
Diabetes Care
|
2007
|
1.61
|
|
121
|
Genetic association for renal traits among participants of African ancestry reveals new loci for renal function.
|
PLoS Genet
|
2011
|
1.60
|
|
122
|
Association of oxidative stress, insulin resistance, and diabetes risk phenotypes: the Framingham Offspring Study.
|
Diabetes Care
|
2007
|
1.60
|
|
123
|
Peri-aortic fat, cardiovascular disease risk factors, and aortic calcification: the Framingham Heart Study.
|
Atherosclerosis
|
2010
|
1.60
|
|
124
|
Simple area-based measurement for multidetector computed tomography to predict left ventricular size.
|
Eur Radiol
|
2010
|
1.59
|
|
125
|
Genome-wide association with diabetes-related traits in the Framingham Heart Study.
|
BMC Med Genet
|
2007
|
1.59
|
|
126
|
Variants in the CNR1 and the FAAH genes and adiposity traits in the community.
|
Obesity (Silver Spring)
|
2009
|
1.58
|
|
127
|
Characteristics and in-hospital outcomes of patients with non-ST-segment elevation myocardial infarction and chronic kidney disease undergoing percutaneous coronary intervention.
|
JACC Cardiovasc Interv
|
2011
|
1.57
|
|
128
|
Chronic kidney disease as a predictor of cardiovascular disease (from the Framingham Heart Study).
|
Am J Cardiol
|
2008
|
1.56
|
|
129
|
Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels.
|
Hum Mol Genet
|
2010
|
1.53
|
|
130
|
Overlap between common genetic polymorphisms underpinning kidney traits and cardiovascular disease phenotypes: the CKDGen consortium.
|
Am J Kidney Dis
|
2013
|
1.52
|
|
131
|
Cardiac natriuretic peptides, obesity, and insulin resistance: evidence from two community-based studies.
|
J Clin Endocrinol Metab
|
2011
|
1.50
|
|
132
|
Type 1 diabetes mellitus and cardiovascular disease: a scientific statement from the American Heart Association and American Diabetes Association.
|
Diabetes Care
|
2014
|
1.47
|
|
133
|
Axial area and anteroposterior diameter as estimates of left atrial size using computed tomography of the chest: comparison with 3-dimensional volume.
|
J Cardiovasc Comput Tomogr
|
2009
|
1.47
|
|
134
|
Inflammation, kidney function and albuminuria in the Framingham Offspring cohort.
|
Nephrol Dial Transplant
|
2010
|
1.46
|
|
135
|
Hemostatic markers of endothelial dysfunction and risk of incident type 2 diabetes: the Framingham Offspring Study.
|
Diabetes
|
2006
|
1.46
|
|
136
|
A combined epidemiologic and metabolomic approach improves CKD prediction.
|
J Am Soc Nephrol
|
2013
|
1.42
|
|
137
|
A genome-wide association for kidney function and endocrine-related traits in the NHLBI's Framingham Heart Study.
|
BMC Med Genet
|
2007
|
1.42
|
|
138
|
Arterial stiffness in mild-to-moderate CKD.
|
J Am Soc Nephrol
|
2009
|
1.41
|
|
139
|
Fatty liver, abdominal adipose tissue and atherosclerotic calcification in African Americans: the Jackson Heart Study.
|
Atherosclerosis
|
2012
|
1.40
|
|
140
|
Overweight, obesity, and elevated serum cystatin C levels in adults in the United States.
|
Am J Med
|
2008
|
1.37
|
|
141
|
Reference values for normal pulmonary artery dimensions by noncontrast cardiac computed tomography: the Framingham Heart Study.
|
Circ Cardiovasc Imaging
|
2011
|
1.34
|
|
142
|
Update on Prevention of Cardiovascular Disease in Adults With Type 2 Diabetes Mellitus in Light of Recent Evidence: A Scientific Statement From the American Heart Association and the American Diabetes Association.
|
Circulation
|
2015
|
1.33
|
|
143
|
Low hemoglobin A1c and risk of all-cause mortality among US adults without diabetes.
|
Circ Cardiovasc Qual Outcomes
|
2010
|
1.33
|
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