Chromatin immunoprecipitation (ChIP).

Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma. Nat Med (2015) 2.05

American Thyroid Association Guide to investigating thyroid hormone economy and action in rodent and cell models. Thyroid (2013) 1.41

Epigenetics of host-pathogen interactions: the road ahead and the road behind. PLoS Pathog (2012) 1.24

The histone acetyltransferase PCAF regulates p21 transcription through stress-induced acetylation of histone H3. Cell Cycle (2012) 1.24

Repair of naturally occurring mismatches can induce mutations in flanking DNA. Elife (2014) 1.06

Role of ChIP-seq in the discovery of transcription factor binding sites, differential gene regulation mechanism, epigenetic marks and beyond. Cell Cycle (2014) 1.01

Erg is a crucial regulator of endocardial-mesenchymal transformation during cardiac valve morphogenesis. Development (2012) 0.98

Mesodermal iPSC-derived progenitor cells functionally regenerate cardiac and skeletal muscle. J Clin Invest (2015) 0.98

Smad7 inhibits autocrine expression of TGF-β2 in intestinal epithelial cells in baboon necrotizing enterocolitis. Am J Physiol Gastrointest Liver Physiol (2012) 0.97

Analysis of chromatin dynamics during glucocorticoid receptor activation. Mol Cell Biol (2012) 0.97

Epigenetic regulation of mesenchymal stem cells: a focus on osteogenic and adipogenic differentiation. Stem Cells Int (2011) 0.96

Activation of the glutaredoxin-1 gene by nuclear factor κB enhances signaling. Free Radic Biol Med (2011) 0.90

Drosophila COP9 signalosome subunit 7 interacts with multiple genomic loci to regulate development. Nucleic Acids Res (2014) 0.89

Patient mutation in AIRE disrupts P-TEFb binding and target gene transcription. Nucleic Acids Res (2011) 0.88

EGCG prevents PCB-126-induced endothelial cell inflammation via epigenetic modifications of NF-κB target genes in human endothelial cells. J Nutr Biochem (2015) 0.88

Feedback modulation of cholesterol metabolism by the lipid-responsive non-coding RNA LeXis. Nature (2016) 0.87

Long Noncoding RNA-Directed Epigenetic Regulation of Gene Expression Is Associated With Anxiety-like Behavior in Mice. Biol Psychiatry (2015) 0.86

Nuclear orphan receptor NR2F6 directly antagonizes NFAT and RORγt binding to the Il17a promoter. J Autoimmun (2012) 0.86

Antagonism versus cooperativity with TALE cofactors at the base of the functional diversification of Hox protein function. PLoS Genet (2013) 0.85

TALE homeodomain proteins regulate site-specific terminal differentiation, LCE genes and epidermal barrier. J Cell Sci (2011) 0.82

Transcriptional and post-transcriptional control of adipocyte differentiation by Jumonji domain-containing protein 6. Nucleic Acids Res (2015) 0.82

CCAAT enhancer binding protein and nuclear factor of activated T cells regulate HIV-1 LTR via a novel conserved downstream site in cells of the monocyte-macrophage lineage. PLoS One (2014) 0.82

The translation initiation factor eIF3i up-regulates vascular endothelial growth factor A, accelerates cell proliferation, and promotes angiogenesis in embryonic development and tumorigenesis. J Biol Chem (2014) 0.82

Polycomb Repressive Complex 1 Generates Discrete Compacted Domains that Change during Differentiation. Mol Cell (2017) 0.82

The zinc finger transcription factor ZXDC activates CCL2 gene expression by opposing BCL6-mediated repression. Mol Immunol (2013) 0.82

Elution of High-affinity (>10-9 KD) Antibodies from Tissue Sections: Clues to the Molecular Mechanism and Use in Sequential Immunostaining. J Histochem Cytochem (2014) 0.81

Improving vascular maturation using noncoding RNAs increases antitumor effect of chemotherapy. JCI Insight (2016) 0.80

Exposure to coplanar PCBs induces endothelial cell inflammation through epigenetic regulation of NF-κB subunit p65. Toxicol Appl Pharmacol (2015) 0.80

LPP inhibits collective cell migration during lung cancer dissemination. Oncogene (2015) 0.80

GATA6 regulates EMT and tumour dissemination, and is a marker of response to adjuvant chemotherapy in pancreatic cancer. Gut (2016) 0.79

Porcine circovirus type 2 activates PI3K/Akt and p38 MAPK pathways to promote interleukin-10 production in macrophages via Cap interaction of gC1qR. Oncotarget (2016) 0.79

CDK11 in TREX/THOC Regulates HIV mRNA 3' End Processing. Cell Host Microbe (2015) 0.78

TR4 Nuclear Receptor Alters the Prostate Cancer CD133+ Stem/Progenitor Cell Invasion via Modulating the EZH2-Related Metastasis Gene Expression. Mol Cancer Ther (2015) 0.78

Resveratrol suppresses myofibroblast activity of human buccal mucosal fibroblasts through the epigenetic inhibition of ZEB1 expression. Oncotarget (2016) 0.78

G-protein-coupled receptor controls steroid hormone signaling in cell membrane. Sci Rep (2015) 0.78

NQO1 Stabilizes p53 in Response to Oncogene-Induced Senescence. Int J Biol Sci (2015) 0.77

ARID3B Directly Regulates Ovarian Cancer Promoting Genes. PLoS One (2015) 0.77

RB localizes to DNA double-strand breaks and promotes DNA end resection and homologous recombination through the recruitment of BRG1. Genes Dev (2016) 0.76

A temporal gate for viral enhancers to co-opt Toll-like-receptor transcriptional activation pathways upon acute infection. PLoS Pathog (2015) 0.76

SF002-96-1, a new drimane sesquiterpene lactone from an Aspergillus species, inhibits survivin expression. Beilstein J Org Chem (2013) 0.76

Ovarian granulosa cells utilize scavenger receptor SR-BI to evade cellular cholesterol homeostatic control for steroid synthesis. J Lipid Res (2012) 0.76

TargetOrtho: a phylogenetic footprinting tool to identify transcription factor targets. Genetics (2014) 0.76

Choosing a suitable method for the identification of replication origins in microbial genomes. Front Microbiol (2015) 0.76

Complex cis-regulatory landscape of the insulin receptor gene underlies the broad expression of a central signaling regulator. Development (2016) 0.75

BCL-3 attenuation of TNFA expression involves an incoherent feed-forward loop regulated by chromatin structure. PLoS One (2013) 0.75

Transcriptional Coactivator and Chromatin Protein PC4 Is Involved in Hippocampal Neurogenesis and Spatial Memory Extinction. J Biol Chem (2016) 0.75

Morph-X-Select: Morphology-based tissue aptamer selection for ovarian cancer biomarker discovery. Biotechniques (2016) 0.75

p53 elevation in human cells halt SV40 infection by inhibiting T-ag expression. Oncotarget (2016) 0.75

Epigenetic Repeat-Induced Gene Silencing in the Chromosomal and Extrachromosomal Contexts in Human Cells. PLoS One (2016) 0.75

SELMAP - SELEX affinity landscape MAPping of transcription factor binding sites using integrated microfluidics. Sci Rep (2016) 0.75

Constitutive Activation of the Nlrc4 Inflammasome Prevents Hepatic Fibrosis and Promotes Hepatic Regeneration after Partial Hepatectomy. Mediators Inflamm (2015) 0.75

HUR protects NONO from degradation by mir320, which is induced by p53 upon UV irradiation. Oncotarget (2016) 0.75

HOXA repression is mediated by nucleoporin Nup93 assisted by its interactors Nup188 and Nup205. Epigenetics Chromatin (2016) 0.75

Chromatin immunoprecipitation from dorsal root ganglia tissue following axonal injury. J Vis Exp (2011) 0.75

Role of Litopenaeus vannamei Yin Yang 1 in the regulation of the white spot syndrome virus immediate-early gene ie1. J Virol (2017) 0.75

Multiplexing of ChIP-Seq Samples in an Optimized Experimental Condition Has Minimal Impact on Peak Detection. PLoS One (2015) 0.75

Differential Regulation of Vascular Endothelial Growth Factors by Promoter-targeted shRNAs. Mol Ther Nucleic Acids (2015) 0.75

Interferon Regulatory Factor 8 (IRF8) Impairs Induction of Interferon Induced with Tetratricopeptide Repeat Motif (IFIT) Gene Family Members. J Biol Chem (2016) 0.75

The cyclic AMP signaling pathway: Exploring targets for successful drug discovery (Review). Mol Med Rep (2016) 0.75

Evidence for genetic regulation of mRNA expression of the dosage-sensitive gene retinoic acid induced-1 (RAI1) in human brain. Sci Rep (2016) 0.75

Activation of TPA-response element present in human Lemur Tyrosine Kinase 2 (lmtk2) gene increases its expression. Biochem Biophys Rep (2017) 0.75

CDK6 protects epithelial ovarian cancer from platinum-induced death via FOXO3 regulation. EMBO Mol Med (2017) 0.75

Intermittent glucocorticoid steroid dosing enhances muscle repair without eliciting muscle atrophy. J Clin Invest (2017) 0.75

Histone H4-K16 acetylation controls chromatin structure and protein interactions. Science (2006) 11.20

A unifying model for the selective regulation of inducible transcription by CpG islands and nucleosome remodeling. Cell (2009) 6.26

A role for Dicer in immune regulation. J Exp Med (2006) 5.81

T cell lineage choice and differentiation in the absence of the RNase III enzyme Dicer. J Exp Med (2005) 5.26

Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication. Genes Dev (2006) 5.15

The insulator binding protein CTCF positions 20 nucleosomes around its binding sites across the human genome. PLoS Genet (2008) 4.91

Selective and antagonistic functions of SWI/SNF and Mi-2beta nucleosome remodeling complexes during an inflammatory response. Genes Dev (2006) 4.61

Transcript dynamics of proinflammatory genes revealed by sequence analysis of subcellular RNA fractions. Cell (2012) 4.10

Mechanical disruption of individual nucleosomes reveals a reversible multistage release of DNA. Proc Natl Acad Sci U S A (2002) 3.52

gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair. Mol Cell (2005) 3.24

Cross-interference of RLR and TLR signaling pathways modulates antibacterial T cell responses. Nat Immunol (2012) 2.72

Molecular biology. Chromatin higher order folding--wrapping up transcription. Science (2002) 2.71

Transcriptional competence and the active marking of tissue-specific enhancers by defined transcription factors in embryonic and induced pluripotent stem cells. Genes Dev (2009) 2.70

Dynamic assembly of silent chromatin during thymocyte maturation. Nat Genet (2004) 2.68

A histone acetylation switch regulates H2A.Z deposition by the SWR-C remodeling enzyme. Science (2013) 2.67

Ikaros DNA-binding proteins as integral components of B cell developmental-stage-specific regulatory circuits. Immunity (2007) 2.65

The SANT domain: a unique histone-tail-binding module? Nat Rev Mol Cell Biol (2004) 2.63

Regulation of B cell fate commitment and immunoglobulin heavy-chain gene rearrangements by Ikaros. Nat Immunol (2008) 2.40

An intensive primary-literature-based teaching program directly benefits undergraduate science majors and facilitates their transition to doctoral programs. CBE Life Sci Educ (2006) 2.37

Essential role for the SANT domain in the functioning of multiple chromatin remodeling enzymes. Mol Cell (2002) 2.33

The Ino80 chromatin-remodeling enzyme regulates replisome function and stability. Nat Struct Mol Biol (2008) 2.30

Global regulation of H2A.Z localization by the INO80 chromatin-remodeling enzyme is essential for genome integrity. Cell (2011) 2.26

DNA translocation and loop formation mechanism of chromatin remodeling by SWI/SNF and RSC. Mol Cell (2006) 2.25

Recruitment of the recombinational repair machinery to a DNA double-strand break in yeast. Mol Cell (2003) 2.17

Rad54p is a chromatin remodeling enzyme required for heteroduplex DNA joint formation with chromatin. J Biol Chem (2003) 2.15

Mechanisms that regulate localization of a DNA double-strand break to the nuclear periphery. Genes Dev (2009) 2.13

Epigenetic characterization of hematopoietic stem cell differentiation using miniChIP and bisulfite sequencing analysis. Proc Natl Acad Sci U S A (2007) 2.13

Interplay between Ino80 and Swr1 chromatin remodeling enzymes regulates cell cycle checkpoint adaptation in response to DNA damage. Genes Dev (2006) 2.05

ATP-dependent chromatin remodeling. Curr Top Dev Biol (2005) 2.02

Selective regulation of lymphopoiesis and leukemogenesis by individual zinc fingers of Ikaros. Nat Immunol (2013) 1.88

A Rik1-associated, cullin-dependent E3 ubiquitin ligase is essential for heterochromatin formation. Genes Dev (2005) 1.87

Structural analysis of the yeast SWI/SNF chromatin remodeling complex. Nat Struct Biol (2003) 1.86

Pioneer factor interactions and unmethylated CpG dinucleotides mark silent tissue-specific enhancers in embryonic stem cells. Proc Natl Acad Sci U S A (2007) 1.81

Histone H3 lysine 56 methylation regulates DNA replication through its interaction with PCNA. Mol Cell (2012) 1.79

Predominant interaction of both Ikaros and Helios with the NuRD complex in immature thymocytes. J Biol Chem (2007) 1.76

Principles of dimer-specific gene regulation revealed by a comprehensive characterization of NF-κB family DNA binding. Nat Immunol (2011) 1.72

Chromatin and the genome integrity network. Nat Rev Genet (2013) 1.72

Phosphorylation of linker histones regulates ATP-dependent chromatin remodeling enzymes. Nat Struct Biol (2002) 1.71

Class-specific regulation of pro-inflammatory genes by MyD88 pathways and IkappaBzeta. J Biol Chem (2008) 1.62

Interleukin-10 inhibits interleukin-12 p40 gene transcription by targeting a late event in the activation pathway. Mol Cell Biol (2004) 1.62

SWI/SNF is required for transcriptional memory at the yeast GAL gene cluster. Genes Dev (2007) 1.61

Probing SWI/SNF remodeling of the nucleosome by unzipping single DNA molecules. Nat Struct Mol Biol (2006) 1.58

C/EBPbeta regulation in lipopolysaccharide-stimulated macrophages. Mol Cell Biol (2003) 1.58

Architecture of the SWI/SNF-nucleosome complex. Mol Cell Biol (2008) 1.58

The SIN domain of the histone octamer is essential for intramolecular folding of nucleosomal arrays. Nat Struct Biol (2002) 1.55

DNA instructed displacement of histones H2A and H2B at an inducible promoter. Mol Cell (2004) 1.53

A common mechanism for mitotic inactivation of C2H2 zinc finger DNA-binding domains. Genes Dev (2002) 1.53

A native peptide ligation strategy for deciphering nucleosomal histone modifications. J Biol Chem (2003) 1.53

Automethylation of G9a and its implication in wider substrate specificity and HP1 binding. Nucleic Acids Res (2007) 1.52

Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros transcription factor. Immunity (2003) 1.51

Genome-wide identification of Ikaros targets elucidates its contribution to mouse B-cell lineage specification and pre-B-cell differentiation. Blood (2013) 1.51

Restraint of inflammatory signaling by interdependent strata of negative regulatory pathways. Nat Immunol (2012) 1.49

A c-Rel subdomain responsible for enhanced DNA-binding affinity and selective gene activation. Genes Dev (2005) 1.45

Phosphorylation of histone H4 serine 1 during DNA damage requires casein kinase II in S. cerevisiae. Curr Biol (2005) 1.41

CDK9 regulates AR promoter selectivity and cell growth through serine 81 phosphorylation. Mol Endocrinol (2010) 1.35

Swi3p controls SWI/SNF assembly and ATP-dependent H2A-H2B displacement. Nat Struct Mol Biol (2007) 1.35

ATP-dependent and ATP-independent roles for the Rad54 chromatin remodeling enzyme during recombinational repair of a DNA double strand break. J Biol Chem (2005) 1.31

An inducible enhancer required for Il12b promoter activity in an insulated chromatin environment. Mol Cell Biol (2007) 1.26

NFIL3 is a regulator of IL-12 p40 in macrophages and mucosal immunity. J Immunol (2011) 1.25

Chromatin and transcription: histones continue to make their marks. Nat Cell Biol (2003) 1.25

A conserved Swi2/Snf2 ATPase motif couples ATP hydrolysis to chromatin remodeling. Mol Cell Biol (2005) 1.24

Creating designer histones by native chemical ligation. Methods Enzymol (2004) 1.21

Recombinational repair within heterochromatin requires ATP-dependent chromatin remodeling. Cell (2009) 1.21

Selectivity of the NF-{kappa}B response. Cold Spring Harb Perspect Biol (2009) 1.20

Nucleosome dynamics regulates DNA processing. Nat Struct Mol Biol (2013) 1.19

Common interaction surfaces of the toll-like receptor 4 cytoplasmic domain stimulate multiple nuclear targets. Mol Cell Biol (2003) 1.16

Control of glycolysis in contracting skeletal muscle. II. Turning it off. Am J Physiol Endocrinol Metab (2002) 1.14

Switching on chromatin: mechanistic role of histone H4-K16 acetylation. Cell Cycle (2006) 1.12

The effect of whey isolate and resistance training on strength, body composition, and plasma glutamine. Int J Sport Nutr Exerc Metab (2006) 1.11

Selective dimerization of a C2H2 zinc finger subfamily. Mol Cell (2003) 1.09

The RSC chromatin remodelling enzyme has a unique role in directing the accurate positioning of nucleosomes. EMBO J (2011) 1.09

Splicing kinetics and transcript release from the chromatin compartment limit the rate of Lipid A-induced gene expression. RNA (2013) 1.08

Heterochromatin assembly: a new twist on an old model. Chromosome Res (2006) 1.08

Immune inhibitory ligand CD200 induction by TLRs and NLRs limits macrophage activation to protect the host from meningococcal septicemia. Cell Host Microbe (2010) 1.08

Modulating acetyl-CoA binding in the GCN5 family of histone acetyltransferases. J Biol Chem (2002) 1.08

DNA repair choice defines a common pathway for recruitment of chromatin regulators. Nat Commun (2013) 1.08

Moderate-intensity resistance exercise training in patients with chronic heart failure improves strength, endurance, heart rate variability, and forearm blood flow. J Card Fail (2004) 1.06

Evaluation of the long-term reconstituting subset of hematopoietic stem cells with CD150. Stem Cells (2009) 1.06

The LRS and SIN domains: two structurally equivalent but functionally distinct nucleosomal surfaces required for transcriptional silencing. Mol Cell Biol (2006) 1.06

Chromatin remodeling activities act on UV-damaged nucleosomes and modulate DNA damage accessibility to photolyase. J Biol Chem (2003) 1.06

Chromatin dynamics during repair of chromosomal DNA double-strand breaks. Epigenomics (2009) 1.05

Dominant role for signal transduction in the transcriptional memory of yeast GAL genes. Mol Cell Biol (2010) 1.03

Effects of whey isolate, creatine, and resistance training on muscle hypertrophy. Med Sci Sports Exerc (2007) 1.03

Fatigue depresses maximal in vitro skeletal muscle Na(+)-K(+)-ATPase activity in untrained and trained individuals. J Appl Physiol (1985) (2002) 1.03

Prolonged exercise to fatigue in humans impairs skeletal muscle Na+-K+-ATPase activity, sarcoplasmic reticulum Ca2+ release, and Ca2+ uptake. J Appl Physiol (1985) (2004) 1.02

Circuit resistance training in chronic heart failure improves skeletal muscle mitochondrial ATP production rate--a randomized controlled trial. J Card Fail (2007) 1.01

Control of glycolysis in contracting skeletal muscle. I. Turning it on. Am J Physiol Endocrinol Metab (2002) 1.01

Transgenic expression of Helios in B lineage cells alters B cell properties and promotes lymphomagenesis. J Immunol (2005) 1.01

A Rad51 presynaptic filament is sufficient to capture nucleosomal homology during recombinational repair of a DNA double-strand break. Mol Cell (2008) 1.00

A distal enhancer in Il12b is the target of transcriptional repression by the STAT3 pathway and requires the basic leucine zipper (B-ZIP) protein NFIL3. J Biol Chem (2011) 0.98

Self-renewal of the long-term reconstituting subset of hematopoietic stem cells is regulated by Ikaros. Stem Cells (2009) 0.98

Upstream of Ikaros. Trends Immunol (2003) 0.96

Micrococcal Nuclease-Southern Blot Assay: I. MNase and Restriction Digestions. CSH Protoc (2007) 0.95

Role of chromatin states in transcriptional memory. Biochim Biophys Acta (2009) 0.94

Assembly of silent chromatin during thymocyte development. Semin Immunol (2005) 0.94

Transcription. Unlocking the gates to gene expression. Science (2002) 0.93

Dignam and Roeder nuclear extract preparation. Cold Spring Harb Protoc (2009) 0.93

Identification of an androgen-dependent enhancer within the prostate stem cell antigen gene. Mol Endocrinol (2002) 0.92