Published in J Immunol on March 29, 2010
Microglial cells contribute to endogenous brain defenses after acute neonatal focal stroke. J Neurosci (2011) 1.64
Reduced GM1 ganglioside in CFTR-deficient human airway cells results in decreased β1-integrin signaling and delayed wound repair. Am J Physiol Cell Physiol (2014) 1.44
Abnormal trafficking and degradation of TLR4 underlie the elevated inflammatory response in cystic fibrosis. J Immunol (2011) 1.31
Dysfunctional CFTR alters the bactericidal activity of human macrophages against Pseudomonas aeruginosa. PLoS One (2011) 1.24
Critical modifier role of membrane-cystic fibrosis transmembrane conductance regulator-dependent ceramide signaling in lung injury and emphysema. J Immunol (2010) 1.14
Rapid structural changes and acidification of guard cell vacuoles during stomatal closure require phosphatidylinositol 3,5-bisphosphate. Plant Cell (2013) 1.01
Defective CFTR expression and function are detectable in blood monocytes: development of a new blood test for cystic fibrosis. PLoS One (2011) 0.98
Coral host cells acidify symbiotic algal microenvironment to promote photosynthesis. Proc Natl Acad Sci U S A (2014) 0.95
Targeting the Intracellular Environment in Cystic Fibrosis: Restoring Autophagy as a Novel Strategy to Circumvent the CFTR Defect. Front Pharmacol (2013) 0.84
Acid sphingomyelinase in macrophage biology. Cell Mol Life Sci (2011) 0.84
Second-hand cigarette smoke impairs bacterial phagocytosis in macrophages by modulating CFTR dependent lipid-rafts. PLoS One (2015) 0.83
Acid sphingomyelinase inhibition protects mice from lung edema and lethal Staphylococcus aureus sepsis. J Mol Med (Berl) (2015) 0.82
TRPC6 channel translocation into phagosomal membrane augments phagosomal function. Proc Natl Acad Sci U S A (2015) 0.80
CFTR activity and mitochondrial function. Redox Biol (2013) 0.79
Hematopoietic and mesenchymal stem cells for the treatment of chronic respiratory diseases: role of plasticity and heterogeneity. ScientificWorldJournal (2014) 0.79
Cystic Fibrosis Lung Immunity: The Role of the Macrophage. J Innate Immun (2016) 0.79
Reactive-oxygen-species-mediated P. aeruginosa killing is functional in human cystic fibrosis macrophages. PLoS One (2013) 0.78
Role of Sphingolipids in the Pathobiology of Lung Inflammation. Mediators Inflamm (2015) 0.77
Avian Influenza Virus Infection of Immortalized Human Respiratory Epithelial Cells Depends upon a Delicate Balance between Hemagglutinin Acid Stability and Endosomal pH. J Biol Chem (2015) 0.77
Partial Restoration of CFTR Function in cftr-Null Mice following Targeted Cell Replacement Therapy. Mol Ther (2017) 0.76
Monosodium Urate Crystals Promote Innate Anti-Mycobacterial Immunity and Improve BCG Efficacy as a Vaccine against Tuberculosis. PLoS One (2015) 0.76
β1-Integrin Accumulates in Cystic Fibrosis Luminal Airway Epithelial Membranes and Decreases Sphingosine, Promoting Bacterial Infections. Cell Host Microbe (2017) 0.75
Modulating Innate and Adaptive Immunity by (R)-Roscovitine: Potential Therapeutic Opportunity in Cystic Fibrosis. J Innate Immun (2016) 0.75
Cysteamine re-establishes the clearance of Pseudomonas aeruginosa by macrophages bearing the cystic fibrosis-relevant F508del-CFTR mutation. Cell Death Dis (2017) 0.75
Staphylococcus aureus Survives in Cystic Fibrosis Macrophages, Forming a Reservoir for Chronic Pneumonia. Infect Immun (2017) 0.75
Human Cystic Fibrosis Macrophages Have Defective Calcium-Dependent Protein Kinase C Activation of the NADPH Oxidase, an Effect Augmented by Burkholderia cenocepacia. J Immunol (2017) 0.75
Liposomes loaded with bioactive lipids enhance antibacterial innate immunity irrespective of drug resistance. Sci Rep (2017) 0.75
Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand. Proc Natl Acad Sci U S A (2007) 7.96
Effects of reduced mucus oxygen concentration in airway Pseudomonas infections of cystic fibrosis patients. J Clin Invest (2002) 6.35
Cystic fibrosis. Lancet (2003) 5.00
Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis. Nat Med (2008) 3.41
PAF-mediated pulmonary edema: a new role for acid sphingomyelinase and ceramide. Nat Med (2004) 2.66
Lipid raft clustering and redox signaling platform formation in coronary arterial endothelial cells. Hypertension (2005) 2.62
Inhaled medication and inhalation devices for lung disease in patients with cystic fibrosis: A European consensus. J Cyst Fibros (2009) 2.59
Dense chromatin activates Polycomb repressive complex 2 to regulate H3 lysine 27 methylation. Science (2012) 2.50
Ceramide-enriched membrane domains. Biochim Biophys Acta (2005) 2.25
Retracted CXCR2 mediates NADPH oxidase-independent neutrophil extracellular trap formation in cystic fibrosis airway inflammation. Nat Med (2010) 2.17
Structure-based modeling of the functional HIV-1 intasome and its inhibition. Proc Natl Acad Sci U S A (2010) 2.16
Liver cell death and anemia in Wilson disease involve acid sphingomyelinase and ceramide. Nat Med (2007) 2.14
Pseudomonas aeruginosa microevolution during cystic fibrosis lung infection establishes clones with adapted virulence. Am J Respir Crit Care Med (2009) 2.08
Organization of the core structure of the postsynaptic density. Proc Natl Acad Sci U S A (2008) 2.06
The requirement for cellular transportin 3 (TNPO3 or TRN-SR2) during infection maps to human immunodeficiency virus type 1 capsid and not integrase. J Virol (2009) 1.99
Development of genome-wide DNA polymorphism database for map-based cloning of rice genes. Plant Physiol (2004) 1.98
Mitochondrial ceramide-rich macrodomains functionalize Bax upon irradiation. PLoS One (2011) 1.86
Anthracyclines induce DNA damage response-mediated protection against severe sepsis. Immunity (2013) 1.83
Biofilm formation, icaADBC transcription, and polysaccharide intercellular adhesin synthesis by staphylococci in a device-related infection model. Infect Immun (2005) 1.78
Genomic evidence for ameiotic evolution in the bdelloid rotifer Adineta vaga. Nature (2013) 1.76
Decreased NKX3.1 protein expression in focal prostatic atrophy, prostatic intraepithelial neoplasia, and adenocarcinoma: association with gleason score and chromosome 8p deletion. Cancer Res (2006) 1.76
How human location-specific contact patterns impact spatial transmission between populations? Sci Rep (2013) 1.74
Targeting Bcl-2-IP3 receptor interaction to reverse Bcl-2's inhibition of apoptotic calcium signals. Mol Cell (2008) 1.71
Light-induced rescue of breathing after spinal cord injury. J Neurosci (2008) 1.68
Molecular architecture of the regulatory Locus sae of Staphylococcus aureus and its impact on expression of virulence factors. J Bacteriol (2003) 1.67
KNN/BNT composite lead-free films for high-frequency ultrasonic transducer applications. IEEE Trans Ultrason Ferroelectr Freq Control (2011) 1.65
Evolution of scaling emergence in large-scale spatial epidemic spreading. PLoS One (2011) 1.64
Prevalence of and racial differences in pterygium: a multiethnic population study in Asians. Ophthalmology (2012) 1.63
Protein kinase A type I and type II define distinct intracellular signaling compartments. Circ Res (2008) 1.62
NOD2 promotes renal injury by exacerbating inflammation and podocyte insulin resistance in diabetic nephropathy. Kidney Int (2013) 1.61
Congenital lethal motor neuron disease with a novel defect in ribosome biogenesis. Neurology (2014) 1.59
Development of integrated preamplifier for high-frequency ultrasonic transducers and low-power handheld receiver. IEEE Trans Ultrason Ferroelectr Freq Control (2011) 1.58
Three common TP53 polymorphisms in susceptibility to breast cancer, evidence from meta-analysis. Breast Cancer Res Treat (2009) 1.56
Serum protein S100A9, SOD3, and MMP9 as new diagnostic biomarkers for pulmonary tuberculosis by iTRAQ-coupled two-dimensional LC-MS/MS. Proteomics (2014) 1.55
Ceramide-mediated clustering is required for CD95-DISC formation. Oncogene (2003) 1.53
CD95 rapidly clusters in cells of diverse origins. Cancer Biol Ther (2003) 1.50
Ceramide-enriched membrane domains--structure and function. Biochim Biophys Acta (2008) 1.49
Intron 3 16 bp duplication polymorphism of TP53 contributes to cancer susceptibility: a meta-analysis. Carcinogenesis (2010) 1.47
Integrated intravascular optical coherence tomography ultrasound imaging system. J Biomed Opt (2010) 1.47
Subcellular organelle lipidomics in TLR-4-activated macrophages. J Lipid Res (2010) 1.46
Scanning peptide array analyses identify overlapping binding sites for the signalling scaffold proteins, beta-arrestin and RACK1, in cAMP-specific phosphodiesterase PDE4D5. Biochem J (2006) 1.46
Ceramide, membrane rafts and infections. J Mol Med (Berl) (2004) 1.45
Photocatalytic oxidation of arsenite over TiO2: is superoxide the main oxidant in normal air-saturated aqueous solutions? Environ Sci Technol (2011) 1.42
Identification of a hybrid PKS/NRPS required for pseurotin A biosynthesis in the human pathogen Aspergillus fumigatus. Chembiochem (2007) 1.42
Patient-specific dose estimation for pediatric chest CT. Med Phys (2008) 1.41
Biological aspects of ceramide-enriched membrane domains. Prog Lipid Res (2007) 1.40
Rapid detection of the ACMG/ACOG-recommended 23 CFTR disease-causing mutations using ion torrent semiconductor sequencing. J Biomol Tech (2012) 1.40
MicroRNAome of porcine pre- and postnatal development. PLoS One (2010) 1.40
Role of Wnt/beta-catenin signaling pathway in epithelial-mesenchymal transition of human prostate cancer induced by hypoxia-inducible factor-1alpha. Int J Urol (2007) 1.36
A Th17- and Th2-skewed cytokine profile in cystic fibrosis lungs represents a potential risk factor for Pseudomonas aeruginosa infection. Am J Respir Crit Care Med (2013) 1.36
Acid sphingomyelinase-ceramide system mediates effects of antidepressant drugs. Nat Med (2013) 1.36
Nucleoporin NUP153 phenylalanine-glycine motifs engage a common binding pocket within the HIV-1 capsid protein to mediate lentiviral infectivity. PLoS Pathog (2013) 1.36
Integrated optical coherence tomography, ultrasound and photoacoustic imaging for ovarian tissue characterization. Biomed Opt Express (2011) 1.35
Reduction of false positives by internal features for polyp detection in CT-based virtual colonoscopy. Med Phys (2005) 1.34
Nitrogen-doped porous carbon nanofiber webs as anodes for lithium ion batteries with a superhigh capacity and rate capability. Adv Mater (2012) 1.33
PSD-95 is required to sustain the molecular organization of the postsynaptic density. J Neurosci (2011) 1.33
High-resolution coregistered intravascular imaging with integrated ultrasound and optical coherence tomography probe. Appl Phys Lett (2010) 1.32
Gold biomineralization by a metallophore from a gold-associated microbe. Nat Chem Biol (2013) 1.31
Cell volume regulatory ion channels in cell proliferation and cell death. Methods Enzymol (2007) 1.31
Activation of Nod-like receptor protein 3 inflammasomes turns on podocyte injury and glomerular sclerosis in hyperhomocysteinemia. Hypertension (2012) 1.31
Suicidal erythrocyte death in sepsis. J Mol Med (Berl) (2006) 1.30
Isolation and characterization of a new ginsenoside from the fresh root of Panax Ginseng. Molecules (2010) 1.30
Reactive oxygen species limit neutrophil life span by activating death receptor signaling. Blood (2004) 1.30
Functional Inhibitors of Acid Sphingomyelinase (FIASMAs): a novel pharmacological group of drugs with broad clinical applications. Cell Physiol Biochem (2010) 1.29
miR-148b functions as a tumor suppressor in pancreatic cancer by targeting AMPKα1. Mol Cancer Ther (2012) 1.29
Ceramide and cell death receptor clustering. Biochim Biophys Acta (2002) 1.29
Acid sphingomyelinase and its redox amplification in formation of lipid raft redox signaling platforms in endothelial cells. Antioxid Redox Signal (2007) 1.28
Rhinoviruses infect human epithelial cells via ceramide-enriched membrane platforms. J Biol Chem (2005) 1.28
An improved electronic colon cleansing method for detection of colonic polyps by virtual colonoscopy. IEEE Trans Biomed Eng (2006) 1.28
Roles of mixing patterns in cooperation on a scale-free networked game. Phys Rev E Stat Nonlin Soft Matter Phys (2007) 1.27
Identification and characterization of PWWP domain residues critical for LEDGF/p75 chromatin binding and human immunodeficiency virus type 1 infectivity. J Virol (2008) 1.27
A novel potassium channel in lymphocyte mitochondria. J Biol Chem (2005) 1.26
Dapper1 is a nucleocytoplasmic shuttling protein that negatively modulates Wnt signaling in the nucleus. J Biol Chem (2008) 1.26
Epstein-Barr virus-induced gene 3 negatively regulates IL-17, IL-22 and RORgamma t. Eur J Immunol (2008) 1.26
Immunisation in the current management of cystic fibrosis patients. J Cyst Fibros (2005) 1.25
NKX-3.1 interacts with prostate-derived Ets factor and regulates the activity of the PSA promoter. Cancer Res (2002) 1.25
Novel combined miniature optical coherence tomography ultrasound probe for in vivo intravascular imaging. J Biomed Opt (2011) 1.25
Ceramide-rich membrane rafts mediate CD40 clustering. J Immunol (2002) 1.24
Effect of treatment with dornase alpha on airway inflammation in patients with cystic fibrosis. Am J Respir Crit Care Med (2003) 1.24
miRNA-141, downregulated in pancreatic cancer, inhibits cell proliferation and invasion by directly targeting MAP4K4. Mol Cancer Ther (2013) 1.23
MiR-130b is a prognostic marker and inhibits cell proliferation and invasion in pancreatic cancer through targeting STAT3. PLoS One (2013) 1.23
Cystic fibrosis and innate immunity: how chloride channel mutations provoke lung disease. Cell Microbiol (2008) 1.22
Colistin-tobramycin combinations are superior to monotherapy concerning the killing of biofilm Pseudomonas aeruginosa. J Infect Dis (2010) 1.21
Sequence diversity of the mucABD locus in Pseudomonas aeruginosa isolates from patients with cystic fibrosis. Microbiology (2006) 1.20
Integrated ultrasound and photoacoustic probe for co-registered intravascular imaging. J Biomed Opt (2011) 1.20
Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes. Proc Natl Acad Sci U S A (2008) 1.20
Biological cost of hypermutation in Pseudomonas aeruginosa strains from patients with cystic fibrosis. Microbiology (2007) 1.20
Mortality and morbidity associated with simultaneous bilateral or staged bilateral total knee arthroplasty: a meta-analysis. Arch Orthop Trauma Surg (2011) 1.19
Six cytotoxic annonaceous acetogenins from Annona squamosa seeds. Food Chem (2012) 1.19
HRP2 determines the efficiency and specificity of HIV-1 integration in LEDGF/p75 knockout cells but does not contribute to the antiviral activity of a potent LEDGF/p75-binding site integrase inhibitor. Nucleic Acids Res (2012) 1.18
Pim kinase substrate identification and specificity. J Biochem (2007) 1.17
Sphingolipids in the lungs. Am J Respir Crit Care Med (2008) 1.17
Repression of seed maturation genes by a trihelix transcriptional repressor in Arabidopsis seedlings. Plant Cell (2009) 1.15
Flagellin induces myeloid-derived suppressor cells: implications for Pseudomonas aeruginosa infection in cystic fibrosis lung disease. J Immunol (2012) 1.15
Antidiabetic effects of malonyl ginsenosides from Panax ginseng on type 2 diabetic rats induced by high-fat diet and streptozotocin. J Ethnopharmacol (2012) 1.15