Published in Nucleic Acids Res on May 12, 2010
antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences. Nucleic Acids Res (2011) 9.22
antiSMASH 2.0--a versatile platform for genome mining of secondary metabolite producers. Nucleic Acids Res (2013) 8.10
Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. Nat Prod Rep (2013) 5.38
BAGEL3: Automated identification of genes encoding bacteriocins and (non-)bactericidal posttranslationally modified peptides. Nucleic Acids Res (2013) 3.23
Genome mining for ribosomally synthesized natural products. Curr Opin Chem Biol (2010) 1.58
Microbial metabolic exchange--the chemotype-to-phenotype link. Nat Chem Biol (2011) 1.55
DAMPD: a manually curated antimicrobial peptide database. Nucleic Acids Res (2011) 1.24
CAMP: Collection of sequences and structures of antimicrobial peptides. Nucleic Acids Res (2013) 1.24
Primer on agar-based microbial imaging mass spectrometry. J Bacteriol (2012) 1.22
Expanding the biotechnology potential of lactobacilli through comparative genomics of 213 strains and associated genera. Nat Commun (2015) 1.22
LAMP: A Database Linking Antimicrobial Peptides. PLoS One (2013) 1.21
Triggers and cues that activate antibiotic production by actinomycetes. J Ind Microbiol Biotechnol (2013) 1.14
Genome mining demonstrates the widespread occurrence of gene clusters encoding bacteriocins in cyanobacteria. PLoS One (2011) 1.11
Computational approaches to natural product discovery. Nat Chem Biol (2015) 1.05
In silico analysis highlights the frequency and diversity of type 1 lantibiotic gene clusters in genome sequenced bacteria. BMC Genomics (2010) 1.04
ThioFinder: a web-based tool for the identification of thiopeptide gene clusters in DNA sequences. PLoS One (2012) 0.94
Pep2Path: automated mass spectrometry-guided genome mining of peptidic natural products. PLoS Comput Biol (2014) 0.92
Database-Guided Discovery of Potent Peptides to Combat HIV-1 or Superbugs. Pharmaceuticals (Basel) (2013) 0.90
Genome mining for methanobactins. BMC Biol (2013) 0.90
Improved methods for classification, prediction, and design of antimicrobial peptides. Methods Mol Biol (2015) 0.89
Draft genomes of gammaproteobacterial methanotrophs isolated from terrestrial ecosystems. Genome Announc (2015) 0.88
Draft genome sequence of Paenibacillus polymyxa OSY-DF, which coproduces a lantibiotic, paenibacillin, and polymyxin E1. J Bacteriol (2012) 0.87
Comparative genome analysis of Streptococcus infantarius subsp. infantarius CJ18, an African fermented camel milk isolate with adaptations to dairy environment. BMC Genomics (2013) 0.87
Comparative genomics analysis of Streptococcus isolates from the human small intestine reveals their adaptation to a highly dynamic ecosystem. PLoS One (2013) 0.87
Independent Co-Option of a Tailed Bacteriophage into a Killing Complex in Pseudomonas. MBio (2015) 0.86
Complete genome sequence of Streptococcus mutans GS-5, a serotype c strain. J Bacteriol (2012) 0.86
Class IIa bacteriocins: diversity and new developments. Int J Mol Sci (2012) 0.86
Novel LanT associated lantibiotic clusters identified by genome database mining. PLoS One (2014) 0.85
Genome Sequence and Transcriptome Analysis of Meat-Spoilage-Associated Lactic Acid Bacterium Lactococcus piscium MKFS47. Appl Environ Microbiol (2015) 0.81
Activation of the SMU.1882 transcription by CovR in Streptococcus mutans. PLoS One (2010) 0.80
BactPepDB: a database of predicted peptides from a exhaustive survey of complete prokaryote genomes. Database (Oxford) (2014) 0.80
Genomics-Based Exploration of Virulence Determinants and Host-Specific Adaptations of Pseudomonas syringae Strains Isolated from Grasses. Pathogens (2014) 0.79
Metabolic profiling as a tool for prioritizing antimicrobial compounds. J Ind Microbiol Biotechnol (2015) 0.78
Complete genome sequence of Leuconostoc gelidum subsp. gasicomitatum KG16-1, isolated from vacuum-packaged vegetable sausages. Stand Genomic Sci (2016) 0.77
A large-scale structural classification of antimicrobial peptides. Biomed Res Int (2015) 0.77
Improved Draft Genome Sequence of Probiotic Strain Lactobacillus gasseri K7. Genome Announc (2014) 0.76
Genome analysis of environmental and clinical P. aeruginosa isolates from sequence type-1146. PLoS One (2014) 0.76
Mechanistic Understanding of Lanthipeptide Biosynthetic Enzymes. Chem Rev (2017) 0.75
Analyses of the probiotic property and stress resistance-related genes of Lactococcus lactis subsp. lactis NCDO 2118 through comparative genomics and in vitro assays. PLoS One (2017) 0.75
Genomic Diversity of Enterotoxigenic Strains of Bacteroides fragilis. PLoS One (2016) 0.75
Draft Genome Sequence of the Bacteriocin-Producing Bradyrhizobium japonicum Strain FN1. Genome Announc (2015) 0.75
The pangenome of (Antarctic) Pseudoalteromonas bacteria: evolutionary and functional insights. BMC Genomics (2017) 0.75
Lactobacillus oligofermentans glucose, ribose and xylose transcriptomes show higher similarity between glucose and xylose catabolism-induced responses in the early exponential growth phase. BMC Genomics (2016) 0.75
High Throughput Identification of Antimicrobial Peptides from Fish Gastrointestinal Microbiota. Toxins (Basel) (2017) 0.75
Basic local alignment search tool. J Mol Biol (1990) 659.07
BLAT--the BLAST-like alignment tool. Genome Res (2002) 126.78
Identifying bacterial genes and endosymbiont DNA with Glimmer. Bioinformatics (2007) 47.63
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Combining evidence using p-values: application to sequence homology searches. Bioinformatics (1998) 16.51
Bacteriocins: developing innate immunity for food. Nat Rev Microbiol (2005) 5.77
A primer on metagenomics. PLoS Comput Biol (2010) 4.40
Lantibiotics: peptides of diverse structure and function. Annu Rev Microbiol (2007) 4.00
Lantibiotics: mode of action, biosynthesis and bioengineering. Curr Pharm Biotechnol (2009) 2.56
The continuing story of class IIa bacteriocins. Microbiol Mol Biol Rev (2006) 2.39
Discovery of unique lanthionine synthetases reveals new mechanistic and evolutionary insights. PLoS Biol (2010) 1.74
Identification of a novel two-peptide lantibiotic, lichenicidin, following rational genome mining for LanM proteins. Appl Environ Microbiol (2009) 1.68
BAGEL: a web-based bacteriocin genome mining tool. Nucleic Acids Res (2006) 1.64
Structure-function relationships of the non-lanthionine-containing peptide (class II) bacteriocins produced by gram-positive bacteria. Curr Pharm Biotechnol (2009) 1.59
Genetic features of circular bacteriocins produced by Gram-positive bacteria. FEMS Microbiol Rev (2007) 1.39
The biology of lantibiotics from the lacticin 481 group is coming of age. FEMS Microbiol Rev (2006) 1.38
Genetically engineered bacteriocins and their potential as the next generation of antimicrobials. Curr Pharm Des (2005) 1.10
Comparative study of the pln locus of the quorum-sensing regulated bacteriocin-producing L. plantarum J51 strain. Int J Food Microbiol (2008) 0.95
Genetic screening of lactic acid bacteria of oenological origin for bacteriocin-encoding genes. Food Microbiol (2008) 0.94
Bacteriocins from plant pathogenic bacteria. FEMS Microbiol Lett (2007) 0.93
Complete genome sequence of Lactobacillus plantarum WCFS1. Proc Natl Acad Sci U S A (2003) 8.40
Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. Nat Prod Rep (2013) 5.38
Bistability, epigenetics, and bet-hedging in bacteria. Annu Rev Microbiol (2008) 4.74
Phenotypic variation in bacteria: the role of feedback regulation. Nat Rev Microbiol (2006) 3.73
Complete genome sequence of the prototype lactic acid bacterium Lactococcus lactis subsp. cremoris MG1363. J Bacteriol (2007) 3.43
BAGEL3: Automated identification of genes encoding bacteriocins and (non-)bactericidal posttranslationally modified peptides. Nucleic Acids Res (2013) 3.23
Projector 2: contig mapping for efficient gap-closure of prokaryotic genome sequence assemblies. Nucleic Acids Res (2005) 3.22
An alternative bactericidal mechanism of action for lantibiotic peptides that target lipid II. Science (2006) 3.05
LysM, a widely distributed protein motif for binding to (peptido)glycans. Mol Microbiol (2008) 2.98
Bet-hedging and epigenetic inheritance in bacterial cell development. Proc Natl Acad Sci U S A (2008) 2.88
Proteomics of protein secretion by Bacillus subtilis: separating the "secrets" of the secretome. Microbiol Mol Biol Rev (2004) 2.67
Subcellular sites for bacterial protein export. Mol Microbiol (2004) 2.50
Stripping Bacillus: ComK auto-stimulation is responsible for the bistable response in competence development. Mol Microbiol (2005) 2.35
Controlling competence in Bacillus subtilis: shared use of regulators. Microbiology (2003) 2.30
Phosphatases modulate the bistable sporulation gene expression pattern in Bacillus subtilis. Mol Microbiol (2005) 2.29
Cell wall attachment of a widely distributed peptidoglycan binding domain is hindered by cell wall constituents. J Biol Chem (2003) 2.28
The Lactococcus lactis CodY regulon: identification of a conserved cis-regulatory element. J Biol Chem (2005) 2.11
A generally applicable validation scheme for the assessment of factors involved in reproducibility and quality of DNA-microarray data. BMC Genomics (2005) 1.96
Genome2D: a visualization tool for the rapid analysis of bacterial transcriptome data. Genome Biol (2004) 1.93
Discovering lactic acid bacteria by genomics. Antonie Van Leeuwenhoek (2002) 1.90
MicroPreP: a cDNA microarray data pre-processing framework. Appl Bioinformatics (2003) 1.86
Improving the predictive value of the competence transcription factor (ComK) binding site in Bacillus subtilis using a genomic approach. Nucleic Acids Res (2002) 1.84
Lantibiotic structures as guidelines for the design of peptides that can be modified by lantibiotic enzymes. Biochemistry (2005) 1.84
The relative value of operon predictions. Brief Bioinform (2008) 1.81
Time-resolved determination of the CcpA regulon of Lactococcus lactis subsp. cremoris MG1363. J Bacteriol (2006) 1.69
Post-translational modification of therapeutic peptides by NisB, the dehydratase of the lantibiotic nisin. Biochemistry (2005) 1.68
FIVA: Functional Information Viewer and Analyzer extracting biological knowledge from transcriptome data of prokaryotes. Bioinformatics (2007) 1.65
CodY of Streptococcus pneumoniae: link between nutritional gene regulation and colonization. J Bacteriol (2007) 1.64
BAGEL: a web-based bacteriocin genome mining tool. Nucleic Acids Res (2006) 1.64
The iturin and fengycin families of lipopeptides are key factors in antagonism of Bacillus subtilis toward Podosphaera fusca. Mol Plant Microbe Interact (2007) 1.61
Transient heterogeneity in extracellular protease production by Bacillus subtilis. Mol Syst Biol (2008) 1.60
Effects of phosphorelay perturbations on architecture, sporulation, and spore resistance in biofilms of Bacillus subtilis. J Bacteriol (2006) 1.56
UniFrag and GenomePrimer: selection of primers for genome-wide production of unique amplicons. Bioinformatics (2003) 1.55
Genome engineering reveals large dispensable regions in Bacillus subtilis. Mol Biol Evol (2003) 1.55
Novel surface display system for proteins on non-genetically modified gram-positive bacteria. Appl Environ Microbiol (2006) 1.53
SpxB regulates O-acetylation-dependent resistance of Lactococcus lactis peptidoglycan to hydrolysis. J Biol Chem (2007) 1.51
Regulation of glutamine and glutamate metabolism by GlnR and GlnA in Streptococcus pneumoniae. J Biol Chem (2006) 1.50
Autolysis of Lactococcus lactis is increased upon D-alanine depletion of peptidoglycan and lipoteichoic acids. J Bacteriol (2005) 1.49
The novel transcriptional regulator SczA mediates protection against Zn2+ stress by activation of the Zn2+-resistance gene czcD in Streptococcus pneumoniae. Mol Microbiol (2007) 1.49
The Rok protein of Bacillus subtilis represses genes for cell surface and extracellular functions. J Bacteriol (2005) 1.49
A novel class of heat and secretion stress-responsive genes is controlled by the autoregulated CssRS two-component system of Bacillus subtilis. J Bacteriol (2002) 1.48
PePPER: a webserver for prediction of prokaryote promoter elements and regulons. BMC Genomics (2012) 1.47
NisT, the transporter of the lantibiotic nisin, can transport fully modified, dehydrated, and unmodified prenisin and fusions of the leader peptide with non-lantibiotic peptides. J Biol Chem (2004) 1.47
Dissection and modulation of the four distinct activities of nisin by mutagenesis of rings A and B and by C-terminal truncation. Appl Environ Microbiol (2007) 1.46
The cop operon is required for copper homeostasis and contributes to virulence in Streptococcus pneumoniae. Mol Microbiol (2011) 1.46
AcmA of Lactococcus lactis is an N-acetylglucosaminidase with an optimal number of LysM domains for proper functioning. FEBS J (2005) 1.45
To have neighbour's fare: extending the molecular toolbox for Streptococcus pneumoniae. Microbiology (2006) 1.45
Temporal separation of distinct differentiation pathways by a dual specificity Rap-Phr system in Bacillus subtilis. Mol Microbiol (2007) 1.44
Overview on sugar metabolism and its control in Lactococcus lactis - the input from in vivo NMR. FEMS Microbiol Rev (2005) 1.44
Live Cell Imaging of Bacillus subtilis and Streptococcus pneumoniae using Automated Time-lapse Microscopy. J Vis Exp (2011) 1.43
Copper stress affects iron homeostasis by destabilizing iron-sulfur cluster formation in Bacillus subtilis. J Bacteriol (2010) 1.40
Molecular Genetics Information System (MOLGENIS): alternatives in developing local experimental genomics databases. Bioinformatics (2004) 1.38
Projector: automatic contig mapping for gap closure purposes. Nucleic Acids Res (2003) 1.38
Production of dehydroamino acid-containing peptides by Lactococcus lactis. Appl Environ Microbiol (2007) 1.36
LmrCD is a major multidrug resistance transporter in Lactococcus lactis. Mol Microbiol (2006) 1.34
Probing direct interactions between CodY and the oppD promoter of Lactococcus lactis. J Bacteriol (2005) 1.29
Cell envelope stress induced by the bacteriocin Lcn972 is sensed by the Lactococcal two-component system CesSR. Mol Microbiol (2007) 1.28
ArgR and AhrC are both required for regulation of arginine metabolism in Lactococcus lactis. J Bacteriol (2004) 1.27
Development of genomic array footprinting for identification of conditionally essential genes in Streptococcus pneumoniae. Appl Environ Microbiol (2007) 1.26
Bet hedging or not? A guide to proper classification of microbial survival strategies. Bioessays (2011) 1.26
Mechanisms and evolution of control logic in prokaryotic transcriptional regulation. Microbiol Mol Biol Rev (2009) 1.25
Transcriptome analysis of temporal regulation of carbon metabolism by CcpA in Bacillus subtilis reveals additional target genes. J Mol Microbiol Biotechnol (2007) 1.25
Transcriptome analysis and related databases of Lactococcus lactis. Antonie Van Leeuwenhoek (2002) 1.25
Identification and characterization of two novel clostridial bacteriocins, circularin A and closticin 574. Appl Environ Microbiol (2003) 1.25
Heterochronic phosphorelay gene expression as a source of heterogeneity in Bacillus subtilis spore formation. J Bacteriol (2010) 1.23
Visualization of differential gene expression by improved cyan fluorescent protein and yellow fluorescent protein production in Bacillus subtilis. Appl Environ Microbiol (2004) 1.21
NisC, the cyclase of the lantibiotic nisin, can catalyze cyclization of designed nonlantibiotic peptides. Biochemistry (2007) 1.21
Directionality and coordination of dehydration and ring formation during biosynthesis of the lantibiotic nisin. J Biol Chem (2009) 1.21
Regulation of the metC-cysK operon, involved in sulfur metabolism in Lactococcus lactis. J Bacteriol (2002) 1.21
Pediocin PA-1, a wide-spectrum bacteriocin from lactic acid bacteria. Crit Rev Food Sci Nutr (2002) 1.21
Genome sequences of Lactococcus lactis MG1363 (revised) and NZ9000 and comparative physiological studies. J Bacteriol (2010) 1.20
Transcriptome analysis reveals mechanisms by which Lactococcus lactis acquires nisin resistance. Antimicrob Agents Chemother (2006) 1.19