Published in Biopolymers on January 01, 2010
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Building complex glycopeptides: Development of a cysteine-free native chemical ligation protocol. Angew Chem Int Ed Engl (2006) 1.53
Studies related to the relative thermodynamic stability of C-terminal peptidyl esters of O-hydroxy thiophenol: emergence of a doable strategy for non-cysteine ligation applicable to the chemical synthesis of glycopeptides. J Am Chem Soc (2006) 1.37
Native chemical ligation at valine: a contribution to peptide and glycopeptide synthesis. Angew Chem Int Ed Engl (2008) 1.34
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Toward homogeneous erythropoietin: chemical synthesis of the Ala1-Gly28 glycopeptide domain by "alanine" ligation. J Am Chem Soc (2009) 1.21
Toward homogeneous erythropoietin: fine tuning of the C-terminal acyl donor in the chemical synthesis of the Cys29-Gly77 glycopeptide domain. J Am Chem Soc (2009) 1.15
Synthesis of peptides by aminolysis of nitrophenyl esters. Nature (1955) 1.10
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A protocol for rapid generation of recombinant adenoviruses using the AdEasy system. Nat Protoc (2007) 5.15
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Pathogenomic sequence analysis of Bacillus cereus and Bacillus thuringiensis isolates closely related to Bacillus anthracis. J Bacteriol (2006) 3.23
Homer binds TRPC family channels and is required for gating of TRPC1 by IP3 receptors. Cell (2003) 3.11
Pattern recognition in retrosynthetic analysis: snapshots in total synthesis. J Org Chem (2007) 3.05
Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet (2013) 2.92
Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity. Nat Med (2011) 2.87
Induction therapy with autologous mesenchymal stem cells in living-related kidney transplants: a randomized controlled trial. JAMA (2012) 2.85
Podocyte-selective deletion of dicer induces proteinuria and glomerulosclerosis. J Am Soc Nephrol (2008) 2.74
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New chemistry with old functional groups: on the reaction of isonitriles with carboxylic acids--a route to various amide types. J Am Chem Soc (2008) 2.61
Pancreatic islet production of vascular endothelial growth factor--a is essential for islet vascularization, revascularization, and function. Diabetes (2006) 2.53
Soluble Eph A receptors inhibit tumor angiogenesis and progression in vivo. Oncogene (2002) 2.41
The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling. J Clin Invest (2008) 2.11
Small molecule natural products in the discovery of therapeutic agents: the synthesis connection. J Org Chem (2006) 2.04
Synthetic analogues of migrastatin that inhibit mammary tumor metastasis in mice. Proc Natl Acad Sci U S A (2005) 2.00
Addressing mechanistic issues in the coupling of isonitriles and carboxylic acids: potential routes to peptidic constructs. J Am Chem Soc (2008) 1.97
On the two-component microwave-mediated reaction of isonitriles with carboxylic acids: regarding alleged formimidate carboxylate mixed anhydrides. J Am Chem Soc (2008) 1.96
Blockade of EphA receptor tyrosine kinase activation inhibits vascular endothelial cell growth factor-induced angiogenesis. Mol Cancer Res (2002) 1.96
A straightforward route to functionalized trans-Diels-Alder motifs. J Am Chem Soc (2010) 1.92
Acetylation modulates cellular distribution and DNA sensing ability of interferon-inducible protein IFI16. Proc Natl Acad Sci U S A (2012) 1.88
Regulation of osteogenic differentiation during skeletal development. Front Biosci (2008) 1.88
A comprehensive analysis of the dual roles of BMPs in regulating adipogenic and osteogenic differentiation of mesenchymal progenitor cells. Stem Cells Dev (2009) 1.87
Improved dienophilicity of nitrocycloalkenes: prospects for the development of a trans-Diels-Alder paradigm. J Am Chem Soc (2009) 1.86
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Seed size, more than nutrient or tannin content, affects seed caching behavior of a common genus of Old World rodents. Ecology (2009) 1.85
Discovery of potent cell migration inhibitors through total synthesis: lessons from structure-activity studies of (+)-migrastatin. J Am Chem Soc (2004) 1.83
EphA2 receptor tyrosine kinase regulates endothelial cell migration and vascular assembly through phosphoinositide 3-kinase-mediated Rac1 GTPase activation. J Cell Sci (2004) 1.82
The ephrins and Eph receptors in angiogenesis. Cytokine Growth Factor Rev (2002) 1.80
Comprehensive proteomic profiling of the membrane constituents of a Mycobacterium tuberculosis strain. Mol Cell Proteomics (2003) 1.77
Recent advances in tumor-targeting anticancer drug conjugates. Bioorg Med Chem (2005) 1.77
Syntheses of Isomerically Pure Reference Octalins and Hydrindanes. Tetrahedron Lett (2009) 1.75
TRP-ML1 is a lysosomal monovalent cation channel that undergoes proteolytic cleavage. J Biol Chem (2005) 1.75
Mycobacterium tuberculosis functional network analysis by global subcellular protein profiling. Mol Biol Cell (2004) 1.73
The ephrin receptor tyrosine kinase A2 is a cellular receptor for Kaposi's sarcoma–associated herpesvirus. Nat Med (2012) 1.72
Applications of total synthesis to problems in neurodegeneration: Fascinating chemistry along the way. Acc Chem Res (2006) 1.72
The migrastatin family: discovery of potent cell migration inhibitors by chemical synthesis. J Am Chem Soc (2004) 1.67
Molecular and cellular approaches for the detection of protein-protein interactions: latest techniques and current limitations. Plant J (2008) 1.62
Monte Carlo based method for fluorescence tomographic imaging with lifetime multiplexing using time gates. Biomed Opt Express (2011) 1.61
Impaired tumor microenvironment in EphA2-deficient mice inhibits tumor angiogenesis and metastatic progression. FASEB J (2005) 1.61
A kinase-dependent role for EphA2 receptor in promoting tumor growth and metastasis. Oncogene (2005) 1.59
Real-time probing of membrane transport in living microbial cells using single nanoparticle optics and living cell imaging. Biochemistry (2004) 1.56
Total synthesis of guanacastepene a: a route to enantiomeric control. J Org Chem (2005) 1.56
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EphA2 receptor tyrosine kinase as a promising target for cancer therapeutics. Curr Cancer Drug Targets (2005) 1.54
BMP-9-induced osteogenic differentiation of mesenchymal progenitors requires functional canonical Wnt/beta-catenin signalling. J Cell Mol Med (2008) 1.54
Osteogenic BMPs promote tumor growth of human osteosarcomas that harbor differentiation defects. Lab Invest (2008) 1.54
Building complex glycopeptides: Development of a cysteine-free native chemical ligation protocol. Angew Chem Int Ed Engl (2006) 1.53
Cued spatial attention drives functionally relevant modulation of the mu rhythm in primary somatosensory cortex. J Neurosci (2010) 1.53
Wnt signaling and human diseases: what are the therapeutic implications? Lab Invest (2007) 1.51
Preparation and evaluation of unimolecular pentavalent and hexavalent antigenic constructs targeting prostate and breast cancer: a synthetic route to anticancer vaccine candidates. J Am Chem Soc (2006) 1.50
Overexpression of EPHA2 receptor destabilizes adherens junctions via a RhoA-dependent mechanism. J Cell Sci (2008) 1.48
Hey1 basic helix-loop-helix protein plays an important role in mediating BMP9-induced osteogenic differentiation of mesenchymal progenitor cells. J Biol Chem (2008) 1.48
Combining Usability Techniques to Design Geovisualization Tools for Epidemiology. Cartogr Geogr Inf Sci (2005) 1.46
High-sensitivity C-reactive protein predicts target organ damage in Chinese patients with metabolic syndrome. Metabolism (2007) 1.45
Kidney transplantation in mice using left and right kidney grafts. J Surg Res (2010) 1.44
Human cytomegalovirus tegument protein pUL83 inhibits IFI16-mediated DNA sensing for immune evasion. Cell Host Microbe (2013) 1.44
Vital roles of mTOR complex 2 in Notch-driven thymocyte differentiation and leukemia. J Exp Med (2012) 1.44
Elevation of receptor tyrosine kinase EphA2 mediates resistance to trastuzumab therapy. Cancer Res (2009) 1.44
Regulation of EphA2 receptor endocytosis by SHIP2 lipid phosphatase via phosphatidylinositol 3-Kinase-dependent Rac1 activation. J Biol Chem (2006) 1.41
The complete genome sequence of Bacillus thuringiensis Al Hakam. J Bacteriol (2007) 1.40
Toward homogeneous erythropoietin: non-NCL-based chemical synthesis of the Gln78-Arg166 glycopeptide domain. J Am Chem Soc (2009) 1.39
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Essential role of Vav family guanine nucleotide exchange factors in EphA receptor-mediated angiogenesis. Mol Cell Biol (2006) 1.37
Straightforward synthesis of panaxytriol: an active component of Red Ginseng. J Org Chem (2003) 1.36
Predicting mating patterns from pollination syndromes: the case of "sapromyiophily" in Tacca chantrieri (Taccaceae). Am J Bot (2005) 1.36
Ephrin-B1 transduces signals to activate integrin-mediated migration, attachment and angiogenesis. J Cell Sci (2002) 1.36
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Gelsemine: a thought-provoking target for total synthesis. Angew Chem Int Ed Engl (2003) 1.34
Eph receptor tyrosine kinases in tumor and tumor microenvironment. Curr Pharm Des (2004) 1.33
Full-field time-resolved fluorescence tomography of small animals. Opt Lett (2010) 1.32
A visualization system for space-time and multivariate patterns (VIS-STAMP). IEEE Trans Vis Comput Graph (2006) 1.32
The coupling of isonitriles and carboxylic acids occurring by sequential concerted rearrangement mechanisms. Org Lett (2008) 1.32
Inhibition of VEGF-dependent multistage carcinogenesis by soluble EphA receptors. Neoplasia (2003) 1.30
A membrane protein/signaling protein interaction network for Arabidopsis version AMPv2. Front Physiol (2010) 1.30
Design, synthesis, and biological evaluation of new-generation taxoids. J Med Chem (2008) 1.29
Discovery of (E)-9,10-dehydroepothilones through chemical synthesis: on the emergence of 26-trifluoro-(E)-9,10-dehydro-12,13-desoxyepothilone B as a promising anticancer drug candidate. J Am Chem Soc (2004) 1.28
On the remarkable antitumor properties of fludelone: how we got there. Angew Chem Int Ed Engl (2005) 1.28
High regeneration capacity helps tropical seeds to counter rodent predation. Oecologia (2011) 1.28
Synthetic carbohydrate-based antitumor vaccines: challenges and opportunities. Expert Rev Vaccines (2005) 1.27
Preparation and reactions of N-thioformyl peptides from amino thioacids and isonitriles. Tetrahedron Lett (2009) 1.27
Prospects for total synthesis: a vision for a totally synthetic vaccine targeting epithelial tumors. Proc Natl Acad Sci U S A (2004) 1.27
Ephrin-A1 facilitates mammary tumor metastasis through an angiogenesis-dependent mechanism mediated by EphA receptor and vascular endothelial growth factor in mice. Cancer Res (2006) 1.27
Development of efficient methods for accomplishing cysteine-free peptide and glycopeptide coupling. Angew Chem Int Ed Engl (2007) 1.27
S-Nitrosylation of DRP1 does not affect enzymatic activity and is not specific to Alzheimer's disease. J Alzheimers Dis (2010) 1.26
Development of an optical imaging platform for functional imaging of small animals using wide-field excitation. Biomed Opt Express (2010) 1.26
Identification and functional analysis of phosphorylated tyrosine residues within EphA2 receptor tyrosine kinase. J Biol Chem (2008) 1.24
Thio FCMA intermediates as strong acyl donors: a general solution to the formation of complex amide bonds. J Am Chem Soc (2009) 1.23
Establishment and characterization of a new highly metastatic human osteosarcoma cell line. Clin Exp Metastasis (2009) 1.23
A Diels-Alder Route to Angularly Functionalized Bicyclic Structures. Tetrahedron (2010) 1.23
Eph/ephrin profiling in human breast cancer reveals significant associations between expression level and clinical outcome. PLoS One (2011) 1.22
Noncatalytic reaction of isonitriles and carboxylic acids en route to amide-type linkages. Nat Protoc (2008) 1.21
The total synthesis of (+/-)-11-O-debenzoyltashironin. J Am Chem Soc (2006) 1.21