Published in Database (Oxford) on July 29, 2010
Reactome: a database of reactions, pathways and biological processes. Nucleic Acids Res (2010) 11.23
Annotating cancer variants and anti-cancer therapeutics in reactome. Cancers (Basel) (2012) 2.35
The Reactome BioMart. Database (Oxford) (2011) 1.66
The G protein-coupled receptor heterodimer network (GPCR-HetNet) and its hub components. Int J Mol Sci (2014) 0.89
Advancements in therapeutically targeting orphan GPCRs. Front Pharmacol (2015) 0.77
The Universal Protein Resource (UniProt) 2009. Nucleic Acids Res (2008) 14.82
How many drug targets are there? Nat Rev Drug Discov (2006) 14.22
Reactome: a knowledge base of biologic pathways and processes. Genome Biol (2007) 13.36
Guide to Receptors and Channels (GRAC), 3rd edition. Br J Pharmacol (2008) 13.18
The Gene Ontology in 2010: extensions and refinements. Nucleic Acids Res (2009) 11.49
Ensembl's 10th year. Nucleic Acids Res (2009) 10.82
The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints. Mol Pharmacol (2003) 9.99
Chemical Entities of Biological Interest: an update. Nucleic Acids Res (2009) 8.92
RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor. Nature (1998) 5.98
Heterodimerization is required for the formation of a functional GABA(B) receptor. Nature (1998) 5.59
A human functional protein interaction network and its application to cancer data analysis. Genome Biol (2010) 4.73
A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons. Cell (2001) 3.52
The G protein-coupled receptor repertoires of human and mouse. Proc Natl Acad Sci U S A (2003) 3.24
Sensing odorants and pheromones with chemosensory receptors. Annu Rev Physiol (2009) 2.87
Molecular mechanisms of ligand binding, signaling, and regulation within the superfamily of G-protein-coupled receptors: molecular modeling and mutagenesis approaches to receptor structure and function. Pharmacol Ther (2004) 2.44
Receptors coupled to heterotrimeric G proteins of the G12 family. Trends Pharmacol Sci (2005) 1.76
Regulation of RhoGEF proteins by G12/13-coupled receptors. Br J Pharmacol (2009) 1.45
An escort for GPCRs: implications for regulation of receptor density at the cell surface. Trends Pharmacol Sci (2008) 1.29
The identification of ligands at orphan G-protein coupled receptors. Annu Rev Pharmacol Toxicol (2004) 1.23
The role of GPCR dimerisation/oligomerisation in receptor signalling. Ernst Schering Found Symp Proc (2006) 1.12
When a G protein-coupled receptor does not couple to a G protein. Mol Biosyst (2007) 1.04
Orphan GPCRs and their ligands. Pharmacol Ther (2005) 1.02
RAMPs: accessory proteins for seven transmembrane domain receptors. Trends Pharmacol Sci (1999) 0.95
Maximizing serendipity: strategies for identifying ligands for orphan G-protein-coupled receptors. Curr Opin Pharmacol (2003) 0.91
Accessory proteins for heterotrimeric G-protein: Implication in the cardiovascular system. Pathophysiology (2009) 0.85
Detection of G protein-coupled receptor-mediated cellular response involved in cytoskeletal rearrangement using surface plasmon resonance. Biosens Bioelectron (2009) 0.84
Velvet: algorithms for de novo short read assembly using de Bruijn graphs. Genome Res (2008) 151.16
Initial sequencing and comparative analysis of the mouse genome. Nature (2002) 96.15
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007) 75.09
The Bioperl toolkit: Perl modules for the life sciences. Genome Res (2002) 58.63
The Pfam protein families database. Nucleic Acids Res (2002) 51.34
The generic genome browser: a building block for a model organism system database. Genome Res (2002) 42.64
Patterns of somatic mutation in human cancer genomes. Nature (2007) 38.41
The minimum information about a genome sequence (MIGS) specification. Nat Biotechnol (2008) 31.04
Automated generation of heuristics for biological sequence comparison. BMC Bioinformatics (2005) 24.54
Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Nature (2004) 24.40
A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis. Nat Biotechnol (2008) 21.72
The genome sequence of the malaria mosquito Anopheles gambiae. Science (2002) 20.36
International network of cancer genome projects. Nature (2010) 20.35
A small-cell lung cancer genome with complex signatures of tobacco exposure. Nature (2009) 18.39
The Sequence Ontology: a tool for the unification of genome annotations. Genome Biol (2005) 18.20
EnsMart: a generic system for fast and flexible access to biological data. Genome Res (2004) 17.64
Evolutionary and biomedical insights from the rhesus macaque genome. Science (2007) 16.21
Reactome knowledgebase of human biological pathways and processes. Nucleic Acids Res (2008) 15.69
The consensus coding sequence (CCDS) project: Identifying a common protein-coding gene set for the human and mouse genomes. Genome Res (2009) 14.90
Ensembl 2011. Nucleic Acids Res (2010) 14.68
The International Protein Index: an integrated database for proteomics experiments. Proteomics (2004) 14.67
Ensembl 2012. Nucleic Acids Res (2011) 14.55
Reactome: a knowledge base of biologic pathways and processes. Genome Biol (2007) 13.36
The genome sequence of Caenorhabditis briggsae: a platform for comparative genomics. PLoS Biol (2003) 13.32
The PRoteomics IDEntifications (PRIDE) database and associated tools: status in 2013. Nucleic Acids Res (2012) 13.14
Promoting coherent minimum reporting guidelines for biological and biomedical investigations: the MIBBI project. Nat Biotechnol (2008) 12.96
EnsemblCompara GeneTrees: Complete, duplication-aware phylogenetic trees in vertebrates. Genome Res (2008) 12.72
Ensembl 2014. Nucleic Acids Res (2013) 12.62
Prepublication data sharing. Nature (2009) 12.24
Unlocking the secrets of the genome. Nature (2009) 11.80
Ensembl 2013. Nucleic Acids Res (2012) 11.70
A common open representation of mass spectrometry data and its application to proteomics research. Nat Biotechnol (2004) 11.42
Optimized design and assessment of whole genome tiling arrays. Bioinformatics (2007) 11.38
Reactome: a database of reactions, pathways and biological processes. Nucleic Acids Res (2010) 11.23
Ensembl's 10th year. Nucleic Acids Res (2009) 10.82
Mouse genomic variation and its effect on phenotypes and gene regulation. Nature (2011) 10.66
The minimum information about a proteomics experiment (MIAPE). Nat Biotechnol (2007) 10.24
Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project. Science (2010) 9.78
Oases: robust de novo RNA-seq assembly across the dynamic range of expression levels. Bioinformatics (2012) 9.68
Comparative genome and proteome analysis of Anopheles gambiae and Drosophila melanogaster. Science (2002) 9.43
Genome sequence of Aedes aegypti, a major arbovirus vector. Science (2007) 9.19
The BioPAX community standard for pathway data sharing. Nat Biotechnol (2010) 9.19
The Ontology Lookup Service, a lightweight cross-platform tool for controlled vocabulary queries. BMC Bioinformatics (2006) 8.68
A high-resolution map of human evolutionary constraint using 29 mammals. Nature (2011) 8.67
The Reactome pathway knowledgebase. Nucleic Acids Res (2013) 8.56
The minimum information required for reporting a molecular interaction experiment (MIMIx). Nat Biotechnol (2007) 8.24
Broadening the horizon--level 2.5 of the HUPO-PSI format for molecular interactions. BMC Biol (2007) 8.03
A standard variation file format for human genome sequences. Genome Biol (2010) 7.83
PRIDE: the proteomics identifications database. Proteomics (2005) 7.52
The IntAct molecular interaction database in 2012. Nucleic Acids Res (2011) 7.49
Enredo and Pecan: genome-wide mammalian consistency-based multiple alignment with paralogs. Genome Res (2008) 7.35
The Ensembl core software libraries. Genome Res (2004) 7.30
The HGNC Database in 2008: a resource for the human genome. Nucleic Acids Res (2007) 7.29
Calling on a million minds for community annotation in WikiProteins. Genome Biol (2008) 7.11
EGASP: the human ENCODE Genome Annotation Assessment Project. Genome Biol (2006) 7.06
Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome. Genome Res (2007) 7.05
Development and mapping of 2240 new SSR markers for rice (Oryza sativa L.). DNA Res (2002) 6.65
Integrating biological data--the Distributed Annotation System. BMC Bioinformatics (2008) 6.56
The European Nucleotide Archive. Nucleic Acids Res (2010) 6.48
Challenges and standards in integrating surveys of structural variation. Nat Genet (2007) 6.05
Heritable individual-specific and allele-specific chromatin signatures in humans. Science (2010) 5.94
Genome analysis of the platypus reveals unique signatures of evolution. Nature (2008) 5.74
The landscape of histone modifications across 1% of the human genome in five human cell lines. Genome Res (2007) 5.67
A guide to the Proteomics Identifications Database proteomics data repository. Proteomics (2009) 5.63
Efficient storage of high throughput DNA sequencing data using reference-based compression. Genome Res (2011) 5.60
Immunity-related genes and gene families in Anopheles gambiae. Science (2002) 5.47
A 3.9-centimorgan-resolution human single-nucleotide polymorphism linkage map and screening set. Am J Hum Genet (2003) 5.34
Petabyte-scale innovations at the European Nucleotide Archive. Nucleic Acids Res (2008) 5.21
The genomic basis of adaptive evolution in threespine sticklebacks. Nature (2012) 5.20
Genome-wide nucleotide-level mammalian ancestor reconstruction. Genome Res (2008) 5.12
PSICQUIC and PSISCORE: accessing and scoring molecular interactions. Nat Methods (2011) 5.01
Improvements to services at the European Nucleotide Archive. Nucleic Acids Res (2009) 5.00
A physical map of the mouse genome. Nature (2002) 4.97
An integrated resource for genome-wide identification and analysis of human tissue-specific differentially methylated regions (tDMRs). Genome Res (2008) 4.84
mzML--a community standard for mass spectrometry data. Mol Cell Proteomics (2010) 4.81
Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors. Genome Res (2012) 4.80
A human functional protein interaction network and its application to cancer data analysis. Genome Biol (2010) 4.73
The Ontology Lookup Service: more data and better tools for controlled vocabulary queries. Nucleic Acids Res (2008) 4.73
Toward interoperable bioscience data. Nat Genet (2012) 4.72
High-resolution genome-wide in vivo footprinting of diverse transcription factors in human cells. Genome Res (2010) 4.69
A database and API for variation, dense genotyping and resequencing data. BMC Bioinformatics (2010) 4.68