Published in Metallomics on May 21, 2010
Mechanism of quinolone action and resistance. Biochemistry (2014) 1.34
Fluoroquinolone-gyrase-DNA complexes: two modes of drug binding. J Biol Chem (2014) 1.08
Topoisomerase II and leukemia. Ann N Y Acad Sci (2014) 1.04
Drug interactions with Bacillus anthracis topoisomerase IV: biochemical basis for quinolone action and resistance. Biochemistry (2011) 1.01
DNA cleavage and opening reactions of human topoisomerase IIα are regulated via Mg2+-mediated dynamic bending of gate-DNA. Proc Natl Acad Sci U S A (2012) 0.99
Iron chelators with topoisomerase-inhibitory activity and their anticancer applications. Antioxid Redox Signal (2012) 0.91
Phytochemicals as Anticancer and Chemopreventive Topoisomerase II Poisons. Phytochem Rev (2014) 0.91
Use of divalent metal ions in the DNA cleavage reaction of topoisomerase IV. Nucleic Acids Res (2011) 0.86
Bypassing fluoroquinolone resistance with quinazolinediones: studies of drug-gyrase-DNA complexes having implications for drug design. ACS Chem Biol (2014) 0.83
Functional determinants of gate-DNA selection and cleavage by bacterial type II topoisomerases. Nucleic Acids Res (2013) 0.82
Catalytic core of human topoisomerase IIα: insights into enzyme-DNA interactions and drug mechanism. Biochemistry (2014) 0.81
QnrS1 structure-activity relationships. J Antimicrob Chemother (2014) 0.78
Metal ion and inter-domain interactions as functional networks in E. coli topoisomerase I. Gene (2013) 0.78
Calcium inhibition of ribonuclease H1 two-metal ion catalysis. J Am Chem Soc (2014) 0.77
Single-molecule Förster resonance energy transfer (FRET) analysis discloses the dynamics of the DNA-topoisomerase II (Top2) interaction in the presence of TOP2-targeting agents. J Biol Chem (2017) 0.75
Novel xanthone-polyamine conjugates as catalytic inhibitors of human topoisomerase IIα. Bioorg Med Chem Lett (2017) 0.75
Interactions between quinolones and Bacillus anthracis gyrase and the basis of drug resistance. Biochemistry (2017) 0.75
DNA topoisomerases: structure, function, and mechanism. Annu Rev Biochem (2001) 12.53
Cellular roles of DNA topoisomerases: a molecular perspective. Nat Rev Mol Cell Biol (2002) 11.79
Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 A resolution. Nature (1998) 10.49
DNA topoisomerases. Annu Rev Biochem (1996) 9.48
Topoisomerase I inhibitors: camptothecins and beyond. Nat Rev Cancer (2006) 9.15
Cloning and primary structure of Staphylococcus aureus DNA topoisomerase IV: a primary target of fluoroquinolones. Mol Microbiol (1994) 7.89
A topoisomerase IIbeta-mediated dsDNA break required for regulated transcription. Science (2006) 6.71
Structure and mechanism of DNA topoisomerase II. Nature (1996) 4.56
Escherichia coli mutants thermosensitive for deoxyribonucleic acid gyrase subunit A: effects on deoxyribonucleic acid replication, transcription, and bacteriophage growth. J Bacteriol (1979) 4.48
Making and breaking nucleic acids: two-Mg2+-ion catalysis and substrate specificity. Mol Cell (2006) 4.26
Crystal structure of an N-terminal fragment of the DNA gyrase B protein. Nature (1991) 3.93
The functional response of upstream DNA to dynamic supercoiling in vivo. Nat Struct Mol Biol (2008) 3.90
DNA topoisomerases: harnessing and constraining energy to govern chromosome topology. Q Rev Biophys (2008) 3.50
Cleavage of DNA by mammalian DNA topoisomerase II. J Biol Chem (1983) 3.05
DNA gyrase and topoisomerase IV: biochemical activities, physiological roles during chromosome replication, and drug sensitivities. Biochim Biophys Acta (1998) 3.00
Metal-ion coordination by U6 small nuclear RNA contributes to catalysis in the spliceosome. Nature (2000) 2.97
Toprim--a conserved catalytic domain in type IA and II topoisomerases, DnaG-type primases, OLD family nucleases and RecR proteins. Nucleic Acids Res (1998) 2.82
Yeast DNA topoisomerase II is encoded by a single-copy, essential gene. Cell (1984) 2.80
Structural basis for gate-DNA recognition and bending by type IIA topoisomerases. Nature (2007) 2.79
Double strand DNA cleavage by type II DNA topoisomerase from Drosophila melanogaster. J Biol Chem (1983) 2.69
The DNA cleavage reaction of topoisomerase II: wolf in sheep's clothing. Nucleic Acids Res (2008) 2.64
Moving one DNA double helix through another by a type II DNA topoisomerase: the story of a simple molecular machine. Q Rev Biophys (1998) 2.62
Conformational and thermodynamic properties of supercoiled DNA. Annu Rev Biophys Biomol Struct (1994) 2.59
Tryptic fragments of the Escherichia coli DNA gyrase A protein. J Biol Chem (1989) 2.56
The DNA dependence of the ATPase activity of DNA gyrase. J Biol Chem (1984) 2.51
Etoposide, topoisomerase II and cancer. Curr Med Chem Anticancer Agents (2005) 2.49
The capture of a DNA double helix by an ATP-dependent protein clamp: a key step in DNA transport by type II DNA topoisomerases. Cell (1992) 2.48
Acids and bases. Science (1966) 2.47
Stretched and overwound DNA forms a Pauling-like structure with exposed bases. Proc Natl Acad Sci U S A (1998) 2.35
Biochemical and pharmacological properties of p170 and p180 forms of topoisomerase II. Biochemistry (1989) 2.26
Cloning and sequencing of cDNA encoding human DNA topoisomerase II and localization of the gene to chromosome region 17q21-22. Proc Natl Acad Sci U S A (1988) 2.26
Stepwise analyses of metal ions in RNase H catalysis from substrate destabilization to product release. EMBO J (2006) 2.23
Understanding the immutability of restriction enzymes: crystal structure of BglII and its DNA substrate at 1.5 A resolution. Nat Struct Biol (2000) 2.22
Topoisomerase II: A specific marker for cell proliferation. J Cell Biol (1986) 2.22
Proliferation- and cell cycle-dependent differences in expression of the 170 kilodalton and 180 kilodalton forms of topoisomerase II in NIH-3T3 cells. Cell Growth Differ (1991) 2.20
Crystal structures of the Klenow fragment of DNA polymerase I complexed with deoxynucleoside triphosphate and pyrophosphate. Biochemistry (1993) 2.19
Eukaryotic topoisomerases recognize nucleic acid topology by preferentially interacting with DNA crossovers. EMBO J (1990) 2.16
DNA topoisomerase IIbeta and neural development. Science (2000) 2.14
Topoisomerase II as a target for anticancer drugs: when enzymes stop being nice. Prog Nucleic Acid Res Mol Biol (2000) 2.13
Yeast DNA topoisomerase II. An ATP-dependent type II topoisomerase that catalyzes the catenation, decatenation, unknotting, and relaxation of double-stranded DNA rings. J Biol Chem (1982) 2.09
Investigating the biological functions of DNA topoisomerases in eukaryotic cells. Biochim Biophys Acta (1998) 2.06
Structural evidence for a two-metal-ion mechanism of group I intron splicing. Science (2005) 2.05
Fluoroquinolones: action and resistance. Curr Top Med Chem (2003) 2.04
Stability constants of Mg2+ and Cd2+ complexes of adenine nucleotides and thionucleotides and rate constants for formation and dissociation of MgATP and MgADP. Biochemistry (1984) 2.01
DNA topoisomerase II, genotoxicity, and cancer. Mutat Res (2007) 1.95
Eukaryotic DNA topoisomerase II beta. Bioessays (1998) 1.83
Structural principles for the inhibition of the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I by phosphorothioates. J Mol Biol (1998) 1.78
The dynamic response of upstream DNA to transcription-generated torsional stress. Nat Struct Mol Biol (2004) 1.74
The Tn7 transposase is a heteromeric complex in which DNA breakage and joining activities are distributed between different gene products. EMBO J (1996) 1.74
Isolation of cDNA clones encoding the beta isozyme of human DNA topoisomerase II and localisation of the gene to chromosome 3p24. Nucleic Acids Res (1992) 1.74
Tying a molecular knot with optical tweezers. Nature (1999) 1.73
The purification and characterization of DNA topoisomerases I and II of the yeast Saccharomyces cerevisiae. J Biol Chem (1984) 1.72
Type II topoisomerases as targets for quinolone antibacterials: turning Dr. Jekyll into Mr. Hyde. Curr Pharm Des (2001) 1.70
Human topoisomerase IIalpha rapidly relaxes positively supercoiled DNA: implications for enzyme action ahead of replication forks. J Biol Chem (2005) 1.68
Dynamics of human DNA topoisomerases IIalpha and IIbeta in living cells. J Cell Biol (2002) 1.67
Purification of topoisomerase II from amsacrine-resistant P388 leukemia cells. Evidence for two forms of the enzyme. J Biol Chem (1987) 1.66
Physiological regulation of eukaryotic topoisomerase II. Biochim Biophys Acta (1998) 1.61
A novel and unified two-metal mechanism for DNA cleavage by type II and IA topoisomerases. Nature (2010) 1.59
Characterization and immunological identification of cDNA clones encoding two human DNA topoisomerase II isozymes. Proc Natl Acad Sci U S A (1989) 1.58
Untangling intracellular DNA topology. Mol Microbiol (2004) 1.57
On the coupling between ATP usage and DNA transport by yeast DNA topoisomerase II. J Biol Chem (1993) 1.56
Involvement of a specific metal ion in the transition of the hammerhead ribozyme to its catalytic conformation. J Biol Chem (1997) 1.55
The role of metals in catalysis by the restriction endonuclease BamHI. Nat Struct Biol (1998) 1.55
Recent advances in understanding structure-function relationships in the type II topoisomerase mechanism. Biochem Soc Trans (2005) 1.55
WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing. Nat Struct Mol Biol (2006) 1.55
Critical role of magnesium ions in DNA polymerase beta's closing and active site assembly. J Am Chem Soc (2004) 1.55
Topoisomerase II inactivation prevents the completion of DNA replication in budding yeast. Mol Cell (2008) 1.54
Visualizing polynucleotide polymerase machines at work. EMBO J (2006) 1.52
DNA gyrase complex with DNA: determinants for site-specific DNA breakage. EMBO J (1986) 1.52
Human DNA topoisomerase I: relaxation, roles, and damage control. Chromosoma (2005) 1.51
Calcium-promoted DNA cleavage by eukaryotic topoisomerase II: trapping the covalent enzyme-DNA complex in an active form. Biochemistry (1987) 1.50
The role of GyrB in the DNA cleavage-religation reaction of DNA gyrase: a proposed two metal-ion mechanism. J Mol Biol (2002) 1.48
Thirty years of Escherichia coli DNA gyrase: from in vivo function to single-molecule mechanism. Biochimie (2007) 1.47
Structural similarities between topoisomerases that cleave one or both DNA strands. Proc Natl Acad Sci U S A (1998) 1.47
Eukaryotic topoisomerase II. Characterization of enzyme turnover. J Biol Chem (1986) 1.46
Effect of antineoplastic agents on the DNA cleavage/religation reaction of eukaryotic topoisomerase II: inhibition of DNA religation by etoposide. Biochemistry (1989) 1.45
Structure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187. Proc Natl Acad Sci U S A (2003) 1.44
A novel endonuclease mechanism directly visualized for I-PpoI. Nat Struct Biol (1999) 1.43
Metal ion catalysis during group II intron self-splicing: parallels with the spliceosome. Genes Dev (1999) 1.42
Proliferation-dependent regulation of DNA topoisomerase II in cultured human cells. Cancer Res (1988) 1.41
Regulation of DNA repair fidelity by molecular checkpoints: "gates" in DNA polymerase beta's substrate selection. Biochemistry (2006) 1.40
Topoisomerase II alpha and topoisomerase II beta genes: characterization and mapping to human chromosomes 17 and 3, respectively. Cancer Res (1992) 1.39
A common topology for bacterial and eukaryotic transcription initiation? EMBO Rep (2007) 1.39
Crystal structures of an NH2-terminal fragment of T4 DNA polymerase and its complexes with single-stranded DNA and with divalent metal ions. Biochemistry (1996) 1.38
Stabilization of eukaryotic topoisomerase II-DNA cleavage complexes. Curr Top Med Chem (2003) 1.36
Thiophilic metal ion rescue of phosphorothioate interference within the Tetrahymena ribozyme P4-P6 domain. RNA (1999) 1.34
Effects of magnesium and related divalent metal ions in topoisomerase structure and function. Nucleic Acids Res (2009) 1.32
Functional compatibility between isoform alpha and beta of type II DNA topoisomerase. J Cell Sci (2004) 1.31
Structures of normal single-stranded DNA and deoxyribo-3'-S-phosphorothiolates bound to the 3'-5' exonucleolytic active site of DNA polymerase I from Escherichia coli. Biochemistry (1999) 1.31
Site-specific cleavage of a DNA hairpin by topoisomerase II. DNA secondary structure as a determinant of enzyme recognition/cleavage. J Biol Chem (1994) 1.30
The why and how of DNA unlinking. Nucleic Acids Res (2009) 1.26
The acidic triad conserved in type IA DNA topoisomerases is required for binding of Mg(II) and subsequent conformational change. J Biol Chem (2000) 1.26
Double-stranded DNA cleavage/religation reaction of eukaryotic topoisomerase II: evidence for a nicked DNA intermediate. Biochemistry (1989) 1.25
Isolation and characterization of a human cDNA clone encoding a novel DNA topoisomerase II homologue from HeLa cells. FEBS Lett (1990) 1.24
Nucleotide-dependent domain movement in the ATPase domain of a human type IIA DNA topoisomerase. J Biol Chem (2005) 1.24
Appendix. II: Alignment of primary sequences of DNA topoisomerases. Adv Pharmacol (1994) 1.23
Hin-mediated DNA knotting and recombining promote replicon dysfunction and mutation. BMC Mol Biol (2007) 1.22
DNA sequence selectivity of topoisomerases and topoisomerase poisons. Biochim Biophys Acta (1998) 1.20
Effects of antineoplastic drugs on the post-strand-passage DNA cleavage/religation equilibrium of topoisomerase II. Biochemistry (1991) 1.19
Isolation and characterization of the gene encoding Drosophila DNA topoisomerase II. Proc Natl Acad Sci U S A (1986) 1.18
DNA topoisomerase II in therapy-related acute promyelocytic leukemia. N Engl J Med (2005) 3.06
The DNA cleavage reaction of topoisomerase II: wolf in sheep's clothing. Nucleic Acids Res (2008) 2.64
DNA topoisomerase II, genotoxicity, and cancer. Mutat Res (2007) 1.95
Human topoisomerase IIalpha rapidly relaxes positively supercoiled DNA: implications for enzyme action ahead of replication forks. J Biol Chem (2005) 1.68
A novel and unified two-metal mechanism for DNA cleavage by type II and IA topoisomerases. Nature (2010) 1.59
Topoisomerase II and the etiology of chromosomal translocations. DNA Repair (Amst) (2006) 1.41
A two-drug model for etoposide action against human topoisomerase IIalpha. J Biol Chem (2002) 1.38
Stabilization of eukaryotic topoisomerase II-DNA cleavage complexes. Curr Top Med Chem (2003) 1.36
Mechanism of quinolone action and resistance. Biochemistry (2014) 1.34
Voreloxin is an anticancer quinolone derivative that intercalates DNA and poisons topoisomerase II. PLoS One (2010) 1.29
From music to macromolecules: using rich media/podcast lecture recordings to enhance the preclinical educational experience. Med Teach (2008) 1.22
Metnase promotes restart and repair of stalled and collapsed replication forks. Nucleic Acids Res (2010) 1.21
1,4-Benzoquinone is a topoisomerase II poison. Biochemistry (2004) 1.21
Human topoisomerase IIalpha uses a two-metal-ion mechanism for DNA cleavage. Nucleic Acids Res (2008) 1.17
(-)-Epigallocatechin gallate, a major constituent of green tea, poisons human type II topoisomerases. Chem Res Toxicol (2008) 1.15
Proteomic analysis of human metaphase chromosomes reveals topoisomerase II alpha as an Aurora B substrate. Nucleic Acids Res (2002) 1.15
The geometry of DNA supercoils modulates topoisomerase-mediated DNA cleavage and enzyme response to anticancer drugs. Biochemistry (2006) 1.12
Polychlorinated biphenyl quinone metabolites poison human topoisomerase IIalpha: altering enzyme function by blocking the N-terminal protein gate. Biochemistry (2006) 1.11
Molecular analysis of t(15;17) genomic breakpoints in secondary acute promyelocytic leukemia arising after treatment of multiple sclerosis. Blood (2008) 1.11
Using 3'-bridging phosphorothiolates to isolate the forward DNA cleavage reaction of human topoisomerase IIalpha. Biochemistry (2008) 1.11
Bioflavonoids as poisons of human topoisomerase II alpha and II beta. Biochemistry (2007) 1.10
Quinone-induced enhancement of DNA cleavage by human topoisomerase IIalpha: adduction of cysteine residues 392 and 405. Biochemistry (2007) 1.10
Direct measurement of DNA bending by type IIA topoisomerases: implications for non-equilibrium topology simplification. Nucleic Acids Res (2011) 1.10
Structure of a topoisomerase II-DNA-nucleotide complex reveals a new control mechanism for ATPase activity. Nat Struct Mol Biol (2012) 1.09
Bimodal recognition of DNA geometry by human topoisomerase II alpha: preferential relaxation of positively supercoiled DNA requires elements in the C-terminal domain. Biochemistry (2008) 1.09
Topoisomerase II and leukemia. Ann N Y Acad Sci (2014) 1.04
Direct monitoring of the strand passage reaction of DNA topoisomerase II triggers checkpoint activation. PLoS Genet (2013) 1.04
Topoisomerase IV-quinolone interactions are mediated through a water-metal ion bridge: mechanistic basis of quinolone resistance. Nucleic Acids Res (2013) 1.04
DNA Topology and Topoisomerases: Teaching a "Knotty" Subject. Biochem Mol Biol Educ (2008) 1.04
Interactions between the etoposide derivative F14512 and human type II topoisomerases: implications for the C4 spermine moiety in promoting enzyme-mediated DNA cleavage. Biochemistry (2011) 1.03
Effects of benzene metabolites on DNA cleavage mediated by human topoisomerase II alpha: 1,4-hydroquinone is a topoisomerase II poison. Chem Res Toxicol (2005) 1.02
Impact of the C-terminal domain of topoisomerase IIalpha on the DNA cleavage activity of the human enzyme. Biochemistry (2005) 1.02
Oxidative metabolites of curcumin poison human type II topoisomerases. Biochemistry (2012) 1.02
Drug interactions with Bacillus anthracis topoisomerase IV: biochemical basis for quinolone action and resistance. Biochemistry (2011) 1.01
N-acetyl-p-benzoquinone imine, the toxic metabolite of acetaminophen, is a topoisomerase II poison. Biochemistry (2004) 1.01
DNA cleavage and opening reactions of human topoisomerase IIα are regulated via Mg2+-mediated dynamic bending of gate-DNA. Proc Natl Acad Sci U S A (2012) 0.99
Interaction between tumor suppressor adenomatous polyposis coli and topoisomerase IIalpha: implication for the G2/M transition. Mol Biol Cell (2008) 0.99
Substituents on etoposide that interact with human topoisomerase IIalpha in the binary enzyme-drug complex: contributions to etoposide binding and activity. Biochemistry (2008) 0.99
Dietary polyphenols as topoisomerase II poisons: B ring and C ring substituents determine the mechanism of enzyme-mediated DNA cleavage enhancement. Chem Res Toxicol (2008) 0.99
Topoisomerase II - drug interaction domains: identification of substituents on etoposide that interact with the enzyme. Biochemistry (2007) 0.98
Biological characterization of MLN944: a potent DNA binding agent. Mol Cancer Ther (2004) 0.97
Cobalt enhances DNA cleavage mediated by human topoisomerase II alpha in vitro and in cultured cells. Biochemistry (2004) 0.97
Site-specific DNA cleavage by Chlorella virus topoisomerase II. Biochemistry (2002) 0.97
Exocyclic DNA lesions stimulate DNA cleavage mediated by human topoisomerase II alpha in vitro and in cultured cells. Biochemistry (2005) 0.96
Overcoming target-mediated quinolone resistance in topoisomerase IV by introducing metal-ion-independent drug-enzyme interactions. ACS Chem Biol (2013) 0.96
Tryptophane-205 of human topoisomerase I is essential for camptothecin inhibition of negative but not positive supercoil removal. Nucleic Acids Res (2007) 0.95
The geometry of DNA supercoils modulates the DNA cleavage activity of human topoisomerase I. Nucleic Acids Res (2010) 0.94
Evidence for direct involvement of epirubicin in the formation of chromosomal translocations in t(15;17) therapy-related acute promyelocytic leukemia. Blood (2009) 0.92
Yeast recombination pathways triggered by topoisomerase II-mediated DNA breaks. Nucleic Acids Res (2003) 0.92
Amsacrine as a topoisomerase II poison: importance of drug-DNA interactions. Biochemistry (2012) 0.90
Mutation of cysteine residue 455 to alanine in human topoisomerase IIalpha confers hypersensitivity to quinones: enhancing DNA scission by closing the N-terminal protein gate. Chem Res Toxicol (2007) 0.89
The efficacy of topoisomerase II-targeted anticancer agents reflects the persistence of drug-induced cleavage complexes in cells. Biochemistry (2008) 0.88
Stimulation of topoisomerase II-mediated DNA cleavage by benzene metabolites. Chem Biol Interact (2005) 0.88
Quinolone action against human topoisomerase IIalpha: stimulation of enzyme-mediated double-stranded DNA cleavage. Biochemistry (2003) 0.88
Use of divalent metal ions in the dna cleavage reaction of human type II topoisomerases. Biochemistry (2009) 0.86
Activation of the DNA-dependent protein kinase by drug-induced and radiation-induced DNA strand breaks. Radiat Res (2003) 0.86
Chlorella virus Marburg topoisomerase II: high DNA cleavage activity as a characteristic of Chlorella virus type II enzymes. Biochemistry (2005) 0.86
Ability of viral topoisomerase II to discern the handedness of supercoiled DNA: bimodal recognition of DNA geometry by type II enzymes. Biochemistry (2006) 0.86
Use of divalent metal ions in the DNA cleavage reaction of topoisomerase IV. Nucleic Acids Res (2011) 0.86
Role of the water-metal ion bridge in mediating interactions between quinolones and Escherichia coli topoisomerase IV. Biochemistry (2014) 0.85
Coordinating the two protomer active sites of human topoisomerase IIalpha: nicks as topoisomerase II poisons. Biochemistry (2009) 0.85
Natural products as topoisomerase II poisons: effects of thymoquinone on DNA cleavage mediated by human topoisomerase IIα. Chem Res Toxicol (2014) 0.84
Prospective tracing of MLL-FRYL clone with low MEIS1 expression from emergence during neuroblastoma treatment to diagnosis of myelodysplastic syndrome. Blood (2008) 0.84
Etoposide quinone is a redox-dependent topoisomerase II poison. Biochemistry (2011) 0.84
Metal ion interactions in the DNA cleavage/ligation active site of human topoisomerase IIalpha. Biochemistry (2009) 0.83
Chiral discrimination and writhe-dependent relaxation mechanism of human topoisomerase IIα. J Biol Chem (2013) 0.83
First ruthenium organometallic complex of antibacterial agent ofloxacin. Crystal structure and interactions with DNA. Inorg Chem (2010) 0.82
Human topoisomerase IIalpha possesses an intrinsic nucleic acid specificity for DNA ligation. Use of 5' covalently activated oligonucleotide substrates to study enzyme mechanism. J Biol Chem (2002) 0.81
Catalytic core of human topoisomerase IIα: insights into enzyme-DNA interactions and drug mechanism. Biochemistry (2014) 0.81
DNA ligation catalyzed by human topoisomerase II alpha. Biochemistry (2004) 0.81
Etoposide quinone is a covalent poison of human topoisomerase IIβ. Biochemistry (2014) 0.80
Epimerization of green tea catechins during brewing does not affect the ability to poison human type II topoisomerases. Chem Res Toxicol (2013) 0.80
Molecular basis of the targeting of topoisomerase II-mediated DNA cleavage by VP16 derivatives conjugated to triplex-forming oligonucleotides. Nucleic Acids Res (2006) 0.80
Topoisomerase IIalpha binding domains of adenomatous polyposis coli influence cell cycle progression and aneuploidy. PLoS One (2010) 0.78
Contributions of the D-Ring to the activity of etoposide against human topoisomerase IIα: potential interactions with DNA in the ternary enzyme--drug--DNA complex. Biochemistry (2011) 0.78
Topoisomerase IB-DNA interactions: X marks the spot. Structure (2010) 0.76
Cleavage of plasmid DNA by eukaryotic topoisomerase II. Methods Mol Biol (2009) 0.75
Activity of quinolone CP-115,955 against bacterial and human type II topoisomerases is mediated by different interactions. Biochemistry (2015) 0.75
DNA methylation impacts the cleavage activity of Chlorella virus topoisomerase II. Biochemistry (2005) 0.75