Published in Infect Immun on October 04, 2010
Manipulation of small Rho GTPases is a pathogen-induced process detected by NOD1. Nature (2013) 1.63
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Microbial amyloids induce interleukin 17A (IL-17A) and IL-22 responses via Toll-like receptor 2 activation in the intestinal mucosa. Infect Immun (2012) 0.95
Nod2 suppresses Borrelia burgdorferi mediated murine Lyme arthritis and carditis through the induction of tolerance. PLoS One (2011) 0.91
Mucosal immunity to pathogenic intestinal bacteria. Nat Rev Immunol (2016) 0.90
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Nucleotide-oligomerization-domain-2 affects commensal gut microbiota composition and intracerebral immunopathology in acute Toxoplasma gondii induced murine ileitis. PLoS One (2014) 0.88
Salmonella Typhimurium Co-Opts the Host Type I IFN System To Restrict Macrophage Innate Immune Transcriptional Responses Selectively. J Immunol (2015) 0.85
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TLR2 regulates neutrophil recruitment and cytokine production with minor contributions from TLR9 during hypersensitivity pneumonitis. PLoS One (2013) 0.81
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Role of mouse peptidoglycan recognition protein PGLYRP2 in the innate immune response to Salmonella enterica serovar Typhimurium infection in vivo. Infect Immun (2012) 0.80
Collaborative action of Toll-like and NOD-like receptors as modulators of the inflammatory response to pathogenic bacteria. Mediators Inflamm (2014) 0.79
Salmonella enterica serovar Typhimurium ΔmsbB triggers exacerbated inflammation in Nod2 deficient mice. PLoS One (2014) 0.78
NOD2 is dispensable for ATG16L1 deficiency-mediated resistance to urinary tract infection. Autophagy (2013) 0.78
Phenotyping of Nod1/2 double deficient mice and characterization of Nod1/2 in systemic inflammation and associated renal disease. Biol Open (2012) 0.78
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A NOD to zebrafish models of inflammatory bowel disease pathogenesis. Dis Model Mech (2011) 0.76
Host-microbial Cross-talk in Inflammatory Bowel Disease. Immune Netw (2017) 0.75
NOD2 dependent neutrophil recruitment is required for early protective immune responses against infectious Litomosoides sigmodontis L3 larvae. Sci Rep (2016) 0.75
A Potential Role of Salmonella Infection in the Onset of Inflammatory Bowel Diseases. Front Immunol (2017) 0.75
Role of nucleotide-binding oligomerization domain 1 (NOD1) and its variants in human cytomegalovirus control in vitro and in vivo. Proc Natl Acad Sci U S A (2016) 0.75
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Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf. Nat Immunol (2006) 9.64
Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease. J Biol Chem (2003) 9.37
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An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid. Nat Immunol (2003) 6.46
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Salmonella exploits caspase-1 to colonize Peyer's patches in a murine typhoid model. J Exp Med (2000) 2.18
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Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity. Immunity (2007) 2.15
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Enteric flora expands gut lamina propria CX3CR1+ dendritic cells supporting inflammatory immune responses under normal and inflammatory conditions. J Immunol (2010) 2.06
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Salmonella typhimurium disseminates within its host by manipulating the motility of infected cells. Proc Natl Acad Sci U S A (2006) 1.42
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Unleashing the therapeutic potential of NOD-like receptors. Nat Rev Drug Discov (2009) 1.39
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Toll signaling: the TIReless quest for specificity. Nat Immunol (2003) 1.00
Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection. J Biol Chem (2003) 10.79
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Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island. Nat Immunol (2004) 7.22
Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry. Nat Immunol (2009) 5.83
Nod-like proteins in immunity, inflammation and disease. Nat Immunol (2006) 5.25
The NLR gene family: a standard nomenclature. Immunity (2008) 4.77
Peptidoglycan molecular requirements allowing detection by Nod1 and Nod2. J Biol Chem (2003) 3.83
Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17-secreting T cells. Blood (2010) 3.06
Bacterial infection causes stress-induced memory dysfunction in mice. Gut (2010) 3.06
Crohn's disease-associated ATG16L1 polymorphism modulates pro-inflammatory cytokine responses selectively upon activation of NOD2. Gut (2011) 2.91
NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-kappaB and JNK pathways by inducing reactive oxygen species production. EMBO Rep (2008) 2.83
Amino acid starvation induced by invasive bacterial pathogens triggers an innate host defense program. Cell Host Microbe (2012) 2.70
Toll-like receptor 2-dependent bacterial sensing does not occur via peptidoglycan recognition. EMBO Rep (2004) 2.64
Nucleotide-binding oligomerization domain-2 modulates specific TLR pathways for the induction of cytokine release. J Immunol (2005) 2.52
Recognition of Staphylococcus aureus by the innate immune system. Clin Microbiol Rev (2005) 2.50
GLP-1 receptor activation indirectly reduces hepatic lipid accumulation but does not attenuate development of atherosclerosis in diabetic male ApoE(-/-) mice. Endocrinology (2012) 2.48
Identification of an innate T helper type 17 response to intestinal bacterial pathogens. Nat Med (2011) 2.48
A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune system. Proc Natl Acad Sci U S A (2007) 2.46
IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1beta and IL-6 production through a caspase 1-dependent mechanism. Proc Natl Acad Sci U S A (2005) 2.46
Shigella induces mitochondrial dysfunction and cell death in nonmyleoid cells. Cell Host Microbe (2009) 2.21
Gene-environment interaction modulated by allelic heterogeneity in inflammatory diseases. Proc Natl Acad Sci U S A (2003) 2.16
Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity. Immunity (2007) 2.15
NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosis. PLoS Pathog (2005) 2.04
Acquisition of a multifunctional IgA+ plasma cell phenotype in the gut. Nature (2011) 2.04
Specific MAIT cell behaviour among innate-like T lymphocytes in critically ill patients with severe infections. Intensive Care Med (2013) 2.02
Conversion of PtdIns(4,5)P(2) into PtdIns(5)P by the S.flexneri effector IpgD reorganizes host cell morphology. EMBO J (2002) 1.94
Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists. Eur J Immunol (2005) 1.90
Bacterial membrane vesicles deliver peptidoglycan to NOD1 in epithelial cells. Cell Microbiol (2009) 1.87
Modulating immunity as a therapy for bacterial infections. Nat Rev Microbiol (2012) 1.86
Nods, Nalps and Naip: intracellular regulators of bacterial-induced inflammation. Cell Microbiol (2003) 1.79
Nod2-dependent Th2 polarization of antigen-specific immunity. J Immunol (2008) 1.78
NLRC5 limits the activation of inflammatory pathways. J Immunol (2010) 1.73
The protein ATG16L1 suppresses inflammatory cytokines induced by the intracellular sensors Nod1 and Nod2 in an autophagy-independent manner. Immunity (2013) 1.71
pH-dependent internalization of muramyl peptides from early endosomes enables Nod1 and Nod2 signaling. J Biol Chem (2009) 1.68
An N-terminal addressing sequence targets NLRX1 to the mitochondrial matrix. J Cell Sci (2009) 1.62
The role of Toll-like receptors and Nod proteins in bacterial infection. Mol Immunol (2004) 1.61
Listeria phospholipases subvert host autophagic defenses by stalling pre-autophagosomal structures. EMBO J (2013) 1.61
Intracellular vs extracellular recognition of pathogens--common concepts in mammals and flies. Trends Microbiol (2002) 1.59
Anti-inflammatory effect of Lactobacillus casei on Shigella-infected human intestinal epithelial cells. J Immunol (2006) 1.55
The role of mitochondria in cellular defense against microbial infection. Semin Immunol (2009) 1.52
NACHT-LRR proteins (NLRs) in bacterial infection and immunity. Trends Microbiol (2005) 1.42
The pattern-recognition molecule Nod1 is localized at the plasma membrane at sites of bacterial interaction. Cell Microbiol (2007) 1.41
Murine Nod1 but not its human orthologue mediates innate immune detection of tracheal cytotoxin. EMBO Rep (2005) 1.41
Unleashing the therapeutic potential of NOD-like receptors. Nat Rev Drug Discov (2009) 1.39
The microbial and danger signals that activate Nod-like receptors. Cytokine (2008) 1.38
NOD1 activators link innate immunity to insulin resistance. Diabetes (2011) 1.38
Parkinson's disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures. J Neural Transm (Vienna) (2011) 1.35
Triggering receptor expressed on myeloid cells-1 (TREM-1) amplifies the signals induced by the NACHT-LRR (NLR) pattern recognition receptors. J Leukoc Biol (2006) 1.34
Peptidoglycan-modifying enzyme Pgp1 is required for helical cell shape and pathogenicity traits in Campylobacter jejuni. PLoS Pathog (2012) 1.34
Role of AmiA in the morphological transition of Helicobacter pylori and in immune escape. PLoS Pathog (2006) 1.34
Mitochondria in innate immunity. EMBO Rep (2011) 1.31
Enhancement of reactive oxygen species production and chlamydial infection by the mitochondrial Nod-like family member NLRX1. J Biol Chem (2010) 1.31
Aspergillus fumigatus induces innate immune responses in alveolar macrophages through the MAPK pathway independently of TLR2 and TLR4. J Immunol (2006) 1.29
Nod1 participates in the innate immune response to Pseudomonas aeruginosa. J Biol Chem (2005) 1.29
The frameshift mutation in Nod2 results in unresponsiveness not only to Nod2- but also Nod1-activating peptidoglycan agonists. J Biol Chem (2005) 1.28
Mitochondrial ROS fuel the inflammasome. Cell Res (2011) 1.26