PubRank

Bernhard Hube

Author PubWeight™ 120.26‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Evolution of pathogenicity and sexual reproduction in eight Candida genomes. Nature 2009 5.90
2 Candida albicans secreted aspartyl proteinases in virulence and pathogenesis. Microbiol Mol Biol Rev 2003 4.07
3 Granulocytes govern the transcriptional response, morphology and proliferation of Candida albicans in human blood. Mol Microbiol 2005 3.00
4 Candida albicans pathogenicity mechanisms. Virulence 2013 2.60
5 In vivo transcript profiling of Candida albicans identifies a gene essential for interepithelial dissemination. Cell Microbiol 2007 2.35
6 Stage-specific gene expression of Candida albicans in human blood. Mol Microbiol 2003 1.97
7 Hydrolytic enzymes as virulence factors of Candida albicans. Mycoses 2005 1.96
8 the hyphal-associated adhesin and invasin Als3 of Candida albicans mediates iron acquisition from host ferritin. PLoS Pathog 2008 1.94
9 Candida albicans hyphal formation and the expression of the Efg1-regulated proteinases Sap4 to Sap6 are required for the invasion of parenchymal organs. Infect Immun 2002 1.82
10 Cellular interactions of Candida albicans with human oral epithelial cells and enterocytes. Cell Microbiol 2009 1.77
11 Glycosylphosphatidylinositol-anchored proteases of Candida albicans target proteins necessary for both cellular processes and host-pathogen interactions. J Biol Chem 2005 1.77
12 Candida albicans proteinases and host/pathogen interactions. Cell Microbiol 2004 1.73
13 Anti-fungal therapy at the HAART of viral therapy. Trends Microbiol 2002 1.72
14 In vivo and ex vivo comparative transcriptional profiling of invasive and non-invasive Candida albicans isolates identifies genes associated with tissue invasion. Mol Microbiol 2007 1.68
15 Human epithelial cells establish direct antifungal defense through TLR4-mediated signaling. J Clin Invest 2007 1.67
16 From attachment to damage: defined genes of Candida albicans mediate adhesion, invasion and damage during interaction with oral epithelial cells. PLoS One 2011 1.54
17 Quantitative expression of the Candida albicans secreted aspartyl proteinase gene family in human oral and vaginal candidiasis. Microbiology 2008 1.52
18 Importance of the Candida albicans cell wall during commensalism and infection. Curr Opin Microbiol 2012 1.50
19 Complement plays a central role in Candida albicans-induced cytokine production by human PBMCs. Eur J Immunol 2012 1.50
20 The secreted aspartyl proteinases Sap1 and Sap2 cause tissue damage in an in vitro model of vaginal candidiasis based on reconstituted human vaginal epithelium. Infect Immun 2003 1.49
21 Interaction of pathogenic yeasts with phagocytes: survival, persistence and escape. Curr Opin Microbiol 2010 1.39
22 An Interspecies Regulatory Network Inferred from Simultaneous RNA-seq of Candida albicans Invading Innate Immune Cells. Front Microbiol 2012 1.35
23 Candida albicans iron acquisition within the host. FEMS Yeast Res 2009 1.35
24 Candida albicans dimorphism as a therapeutic target. Expert Rev Anti Infect Ther 2012 1.34
25 Comparative and functional genomics provide insights into the pathogenicity of dermatophytic fungi. Genome Biol 2011 1.34
26 Candida albicans scavenges host zinc via Pra1 during endothelial invasion. PLoS Pathog 2012 1.34
27 Models of oral and vaginal candidiasis based on in vitro reconstituted human epithelia. Nat Protoc 2006 1.34
28 The facultative intracellular pathogen Candida glabrata subverts macrophage cytokine production and phagolysosome maturation. J Immunol 2011 1.33
29 Comparative genomics using Candida albicans DNA microarrays reveals absence and divergence of virulence-associated genes in Candida dubliniensis. Microbiology 2004 1.29
30 Infection of human oral epithelia with Candida species induces cytokine expression correlated to the degree of virulence. J Invest Dermatol 2002 1.27
31 Polymorphonuclear leukocytes (PMNs) induce protective Th1-type cytokine epithelial responses in an in vitro model of oral candidosis. Microbiology 2004 1.23
32 Expression analysis of the Candida albicans lipase gene family during experimental infections and in patient samples. FEMS Yeast Res 2004 1.20
33 Identifying infection-associated genes of Candida albicans in the postgenomic era. FEMS Yeast Res 2009 1.19
34 Two unlike cousins: Candida albicans and C. glabrata infection strategies. Cell Microbiol 2013 1.19
35 A novel immune evasion strategy of candida albicans: proteolytic cleavage of a salivary antimicrobial peptide. PLoS One 2009 1.18
36 Candida albicans interactions with epithelial cells and mucosal immunity. Microbes Infect 2011 1.17
37 Cellular responses of Candida albicans to phagocytosis and the extracellular activities of neutrophils are critical to counteract carbohydrate starvation, oxidative and nitrosative stress. PLoS One 2012 1.15
38 Exposure of Candida albicans to antifungal agents affects expression of SAP2 and SAP9 secreted proteinase genes. J Antimicrob Chemother 2005 1.13
39 Induction of ERK-kinase signalling triggers morphotype-specific killing of Candida albicans filaments by human neutrophils. Cell Microbiol 2007 1.13
40 Candida albicans-epithelial interactions: dissecting the roles of active penetration, induced endocytosis and host factors on the infection process. PLoS One 2012 1.12
41 Candida albicans-secreted aspartic proteinases modify the epithelial cytokine response in an in vitro model of vaginal candidiasis. Infect Immun 2005 1.11
42 Reduced expression of the hyphal-independent Candida albicans proteinase genes SAP1 and SAP3 in the efg1 mutant is associated with attenuated virulence during infection of oral epithelium. J Med Microbiol 2003 1.11
43 Persistence versus escape: Aspergillus terreus and Aspergillus fumigatus employ different strategies during interactions with macrophages. PLoS One 2012 1.08
44 Secreted aspartic protease cleavage of Candida albicans Msb2 activates Cek1 MAPK signaling affecting biofilm formation and oropharyngeal candidiasis. PLoS One 2012 1.06
45 Ciclopirox olamine treatment affects the expression pattern of Candida albicans genes encoding virulence factors, iron metabolism proteins, and drug resistance factors. Antimicrob Agents Chemother 2003 1.06
46 The yeast Candida albicans evades human complement attack by secretion of aspartic proteases. Mol Immunol 2009 1.06
47 Proteolytic cleavage of covalently linked cell wall proteins by Candida albicans Sap9 and Sap10. Eukaryot Cell 2010 1.03
48 Regulatory network modelling of iron acquisition by a fungal pathogen in contact with epithelial cells. BMC Syst Biol 2010 1.02
49 Thriving within the host: Candida spp. interactions with phagocytic cells. Med Microbiol Immunol 2013 1.02
50 The Candida albicans-specific gene EED1 encodes a key regulator of hyphal extension. PLoS One 2011 1.00
51 Human natural killer cells acting as phagocytes against Candida albicans and mounting an inflammatory response that modulates neutrophil antifungal activity. J Infect Dis 2013 1.00
52 A core filamentation response network in Candida albicans is restricted to eight genes. PLoS One 2013 0.99
53 The Inflammatory response induced by aspartic proteases of Candida albicans is independent of proteolytic activity. Infect Immun 2010 0.98
54 Secreted aspartic proteases of Candida albicans activate the NLRP3 inflammasome. Eur J Immunol 2013 0.98
55 Embryonated eggs as an alternative infection model to investigate Aspergillus fumigatus virulence. Infect Immun 2010 0.97
56 MfLIP1, a gene encoding an extracellular lipase of the lipid-dependent fungus Malassezia furfur. Microbiology 2006 0.96
57 The novel Candida albicans transporter Dur31 Is a multi-stage pathogenicity factor. PLoS Pathog 2012 0.95
58 The glycosylphosphatidylinositol-anchored protease Sap9 modulates the interaction of Candida albicans with human neutrophils. Infect Immun 2009 0.95
59 Processing of predicted substrates of fungal Kex2 proteinases from Candida albicans, C. glabrata, Saccharomyces cerevisiae and Pichia pastoris. BMC Microbiol 2008 0.94
60 Fungal adaptation to the host environment. Curr Opin Microbiol 2009 0.94
61 Host-pathogen interactions and virulence-associated genes during Candida albicans oral infections. Int J Med Microbiol 2011 0.94
62 The role of secreted aspartyl proteinases in Candida albicans keratitis. Invest Ophthalmol Vis Sci 2007 0.93
63 Small but crucial: the novel small heat shock protein Hsp21 mediates stress adaptation and virulence in Candida albicans. PLoS One 2012 0.93
64 Hgc1 mediates dynamic Candida albicans-endothelium adhesion events during circulation. Eukaryot Cell 2009 0.91
65 Factors supporting cysteine tolerance and sulfite production in Candida albicans. Eukaryot Cell 2013 0.90
66 Candida albicans adhesion to and invasion and damage of vaginal epithelial cells: stage-specific inhibition by clotrimazole and bifonazole. Antimicrob Agents Chemother 2011 0.90
67 Functional analysis of the phospholipase C gene CaPLC1 and two unusual phospholipase C genes, CaPLC2 and CaPLC3, of Candida albicans. Microbiology 2005 0.89
68 The early transcriptional response of human granulocytes to infection with Candida albicans is not essential for killing but reflects cellular communications. Infect Immun 2006 0.89
69 Zinc exploitation by pathogenic fungi. PLoS Pathog 2012 0.88
70 Pathogenesis of Candida albicans infections in the alternative chorio-allantoic membrane chicken embryo model resembles systemic murine infections. PLoS One 2011 0.88
71 The pH-regulated antigen 1 of Candida albicans binds the human complement inhibitor C4b-binding protein and mediates fungal complement evasion. J Biol Chem 2011 0.87
72 Oxygen accessibility and iron levels are critical factors for the antifungal action of ciclopirox against Candida albicans. J Antimicrob Chemother 2005 0.86
73 Differential role of NK cells against Candida albicans infection in immunocompetent or immunocompromised mice. Eur J Immunol 2014 0.86
74 Epithelial invasion outcompetes hypha development during Candida albicans infection as revealed by an image-based systems biology approach. Cytometry A 2013 0.86
75 Phenotypic screening, transcriptional profiling, and comparative genomic analysis of an invasive and non-invasive strain of Candida albicans. BMC Microbiol 2008 0.85
76 Immune evasion, stress resistance, and efficient nutrient acquisition are crucial for intracellular survival of Candida glabrata within macrophages. Eukaryot Cell 2013 0.85
77 Candida albicans PLD I activity is required for full virulence. Med Mycol 2004 0.85
78 Pathogenicity mechanisms and host response during oral Candida albicans infections. Expert Rev Anti Infect Ther 2014 0.84
79 Candida glabrata tryptophan-based pigment production via the Ehrlich pathway. Mol Microbiol 2010 0.84
80 Tissue infection and site-specific gene expression in Candida albicans. Adv Appl Microbiol 2003 0.83
81 Multiple functions of DOA1 in Candida albicans. Microbiology 2007 0.82
82 Role of pH-regulated antigen 1 of Candida albicans in the fungal recognition and antifungal response of human neutrophils. Mol Immunol 2011 0.82
83 Transcriptomics in human blood incubation reveals the importance of oxidative stress response in Saccharomyces cerevisiae clinical strains. BMC Genomics 2012 0.82
84 Embryonated chicken eggs as alternative infection model for pathogenic fungi. Methods Mol Biol 2012 0.80
85 Comparison of susceptibility and transcription profile of the new antifungal hassallidin A with caspofungin. Biochem Biophys Res Commun 2006 0.80
86 A peptide derived from the highly conserved protein GAPDH is involved in tissue protection by different antifungal strategies and epithelial immunomodulation. J Invest Dermatol 2012 0.80
87 PGA4, a GAS homologue from Candida albicans, is up-regulated early in infection processes. Fungal Genet Biol 2006 0.79
88 From attachment to invasion: infection associated genes of Candida albicans. Nihon Ishinkin Gakkai Zasshi 2008 0.79
89 Gene acquisition, duplication and metabolic specification: the evolution of fungal methylisocitrate lyases. Environ Microbiol 2011 0.79
90 Candida albicans releases soluble factors that potentiate cytokine production by human cells through a protease-activated receptor 1- and 2-independent pathway. Infect Immun 2009 0.78
91 Effect of antimycotic agents on the activity of aspartyl proteinases secreted by Candida albicans. J Med Microbiol 2003 0.78
92 Serial passaging of Candida albicans in systemic murine infection suggests that the wild type strain SC5314 is well adapted to the murine kidney. PLoS One 2013 0.78
93 Haemoperfused liver as an ex vivo model for organ invasion of Candida albicans. J Med Microbiol 2007 0.78
94 Hsp21 potentiates antifungal drug tolerance in Candida albicans. PLoS One 2013 0.77
95 Global transcriptome sequencing identifies chlamydospore specific markers in Candida albicans and Candida dubliniensis. PLoS One 2013 0.77
96 Candida and Candidosis today: where are we, and where to go? The Interdisciplinary Forum on Candidosis (IFOCAN) 2005, Göttingen (Germany), 23-25 September 2005. FEMS Yeast Res 2006 0.77
97 A family of glutathione peroxidases contributes to oxidative stress resistance in Candida albicans. Med Mycol 2014 0.77
98 HIV-1 and its transmembrane protein gp41 bind to different Candida species modulating adhesion. FEMS Immunol Med Microbiol 2003 0.76
99 Clotrimazole dampens vaginal inflammation and neutrophil infiltration in response to Candida albicans infection. Antimicrob Agents Chemother 2013 0.75
100 Limitation of (1→3)-β-D-glucan monitoring in major elective surgery involving cardiopulmonary bypass. Crit Care 2013 0.75
101 Kex2 protease converts the endoplasmic reticulum alpha1,2-mannosidase of Candida albicans into a soluble cytosolic form. Microbiology 2008 0.75
102 Isolation and amplification of fungal RNA for microarray analysis from host samples. Methods Mol Biol 2012 0.75
103 Corrigendum: Dual-species transcriptional profiling during systemic candidiasis reveals organ-specific host-pathogen interactions. Sci Rep 2016 0.75
104 Introduction: host responses. Methods Mol Biol 2009 0.75