PubRank

Nicole Soranzo

Author PubWeight™ 436.25‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Integrating common and rare genetic variation in diverse human populations. Nature 2010 32.30
2 Biological, clinical and population relevance of 95 loci for blood lipids. Nature 2010 28.21
3 Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet 2010 23.08
4 Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet 2008 22.35
5 Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature 2010 20.01
6 New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet 2010 17.89
7 Genome-wide association analysis identifies 20 loci that influence adult height. Nat Genet 2008 16.92
8 Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet 2008 15.94
9 Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet 2011 13.25
10 Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature 2011 13.25
11 Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet 2009 12.44
12 Variants in MTNR1B influence fasting glucose levels. Nat Genet 2008 10.85
13 Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet 2010 8.89
14 Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet 2010 7.94
15 Mapping cis- and trans-regulatory effects across multiple tissues in twins. Nat Genet 2012 6.97
16 Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. Nat Genet 2010 6.49
17 The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits. PLoS Genet 2012 6.15
18 The architecture of gene regulatory variation across multiple human tissues: the MuTHER study. PLoS Genet 2011 5.95
19 Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet 2009 5.81
20 Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies. Nat Genet 2009 5.32
21 A genome-wide perspective of genetic variation in human metabolism. Nat Genet 2009 5.00
22 A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose. PLoS Genet 2009 4.32
23 Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. Nat Genet 2009 4.28
24 Genome-wide association study identifies five loci associated with lung function. Nat Genet 2009 4.10
25 The UK10K project identifies rare variants in health and disease. Nature 2015 3.89
26 Genetic loci influencing kidney function and chronic kidney disease. Nat Genet 2010 3.75
27 Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation 2011 3.68
28 Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet 2011 3.40
29 Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet 2010 3.37
30 Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet 2013 3.25
31 BLUEPRINT to decode the epigenetic signature written in blood. Nat Biotechnol 2012 3.24
32 Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet 2012 3.21
33 Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes. Nat Genet 2011 3.20
34 New gene functions in megakaryopoiesis and platelet formation. Nature 2011 3.14
35 Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nat Genet 2012 3.04
36 Common variants near TERC are associated with mean telomere length. Nat Genet 2010 2.98
37 Collaborative meta-analysis: associations of 150 candidate genes with osteoporosis and osteoporotic fracture. Ann Intern Med 2009 2.80
38 Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium. Circulation 2010 2.78
39 Seventy-five genetic loci influencing the human red blood cell. Nature 2012 2.77
40 Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nat Genet 2011 2.73
41 Genome-wide association study identifies variants at 9p21 and 22q13 associated with development of cutaneous nevi. Nat Genet 2009 2.65
42 Positive selection on a human-specific transcription factor binding site regulating IL4 expression. Curr Biol 2003 2.59
43 Meta-analysis of genome-wide association data identifies two loci influencing age at menarche. Nat Genet 2009 2.58
44 Association of JAG1 with bone mineral density and osteoporotic fractures: a genome-wide association study and follow-up replication studies. Am J Hum Genet 2010 2.57
45 Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology. Proc Natl Acad Sci U S A 2010 2.47
46 A single-nucleotide polymorphism tagging set for human drug metabolism and transport. Nat Genet 2004 2.44
47 An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits. PLoS Genet 2010 2.43
48 Genetic predictors of the maximum doses patients receive during clinical use of the anti-epileptic drugs carbamazepine and phenytoin. Proc Natl Acad Sci U S A 2005 2.39
49 Ancient and recent positive selection transformed opioid cis-regulation in humans. PLoS Biol 2005 2.37
50 Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension. PLoS Genet 2010 2.24
51 Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. Am J Hum Genet 2010 2.15
52 Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. Nat Genet 2012 2.12
53 A genome-wide association study reveals variants in ARL15 that influence adiponectin levels. PLoS Genet 2009 2.09
54 Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption. Proc Natl Acad Sci U S A 2011 2.01
55 Synthetic associations are unlikely to account for many common disease genome-wide association signals. PLoS Biol 2011 2.00
56 Common variants in the region around Osterix are associated with bone mineral density and growth in childhood. Hum Mol Genet 2009 1.99
57 Male-pattern baldness susceptibility locus at 20p11. Nat Genet 2008 1.87
58 A genome-wide association study identifies three loci associated with mean platelet volume. Am J Hum Genet 2008 1.81
59 Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals. Atherosclerosis 2009 1.78
60 Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. Circulation 2013 1.77
61 Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet 2013 1.72
62 Loci at chromosomes 13, 19 and 20 influence age at natural menopause. Nat Genet 2009 1.72
63 A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One 2012 1.72
64 Multiple loci are associated with white blood cell phenotypes. PLoS Genet 2011 1.65
65 A GWAS sequence variant for platelet volume marks an alternative DNM3 promoter in megakaryocytes near a MEIS1 binding site. Blood 2012 1.59
66 IRF4 variants have age-specific effects on nevus count and predispose to melanoma. Am J Hum Genet 2010 1.55
67 Quantitative trait loci for CD4:CD8 lymphocyte ratio are associated with risk of type 1 diabetes and HIV-1 immune control. Am J Hum Genet 2009 1.51
68 Copy number variation of the APC gene is associated with regulation of bone mineral density. Bone 2012 1.46
69 Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2. Arterioscler Thromb Vasc Biol 2014 1.45
70 Biomarkers for type 2 diabetes and impaired fasting glucose using a nontargeted metabolomics approach. Diabetes 2013 1.44
71 Maps of open chromatin guide the functional follow-up of genome-wide association signals: application to hematological traits. PLoS Genet 2011 1.41
72 Positive selection on MMP3 regulation has shaped heart disease risk. Curr Biol 2004 1.39
73 Human serum metabolic profiles are age dependent. Aging Cell 2012 1.34
74 Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms. PLoS Genet 2011 1.30
75 Ischemic stroke is associated with the ABO locus: the EuroCLOT study. Ann Neurol 2013 1.30
76 Common genetic variation near the phospholamban gene is associated with cardiac repolarisation: meta-analysis of three genome-wide association studies. PLoS One 2009 1.28
77 Loci influencing blood pressure identified using a cardiovascular gene-centric array. Hum Mol Genet 2013 1.27
78 Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation. Blood 2012 1.26
79 The presence of methylation quantitative trait loci indicates a direct genetic influence on the level of DNA methylation in adipose tissue. PLoS One 2013 1.25
80 Population genetic and phylogenetic evidence for positive selection on regulatory mutations at the factor VII locus in humans. Genetics 2004 1.25
81 Association of the 9p21.3 locus with risk of first-ever myocardial infarction in Pakistanis: case-control study in South Asia and updated meta-analysis of Europeans. Arterioscler Thromb Vasc Biol 2010 1.23
82 A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation. PLoS Genet 2012 1.23
83 Identification of PLCL1 gene for hip bone size variation in females in a genome-wide association study. PLoS One 2008 1.21
84 JAK2V617F leads to intrinsic changes in platelet formation and reactivity in a knock-in mouse model of essential thrombocythemia. Blood 2013 1.18
85 The use of genome-wide eQTL associations in lymphoblastoid cell lines to identify novel genetic pathways involved in complex traits. PLoS One 2011 1.18
86 A comprehensive evaluation of potential lung function associated genes in the SpiroMeta general population sample. PLoS One 2011 1.13
87 A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function. PLoS Genet 2013 1.12
88 Maps of open chromatin highlight cell type-restricted patterns of regulatory sequence variation at hematological trait loci. Genome Res 2013 1.10
89 Functional interpretation of non-coding sequence variation: concepts and challenges. Bioessays 2013 1.06
90 A locus on chromosome 1p36 is associated with thyrotropin and thyroid function as identified by genome-wide association study. Am J Hum Genet 2010 1.05
91 Genetic predictors of fibrin D-dimer levels in healthy adults. Circulation 2011 1.05
92 Genes contributing to pain sensitivity in the normal population: an exome sequencing study. PLoS Genet 2012 1.04
93 Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium. Hum Mol Genet 2014 1.02
94 A multicenter study of BRD2 as a risk factor for juvenile myoclonic epilepsy. Epilepsia 2007 0.98
95 A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol. PLoS Genet 2011 0.97
96 Silencing of RhoA nucleotide exchange factor, ARHGEF3, reveals its unexpected role in iron uptake. Blood 2011 0.95
97 Genetic determinants of major blood lipids in Pakistanis compared with Europeans. Circ Cardiovasc Genet 2010 0.95
98 Genome-wide association study identifies two novel regions at 11p15.5-p13 and 1p31 with major impact on acute-phase serum amyloid A. PLoS Genet 2010 0.91
99 Small effective population size and genetic homogeneity in the Val Borbera isolate. Eur J Hum Genet 2012 0.89
100 Genome-wide meta-analysis of common variant differences between men and women. Hum Mol Genet 2012 0.88
101 Influence of ABCB1, ABCC1, ABCC2, and ABCG2 haplotypes on the cellular exposure of nelfinavir in vivo. Pharmacogenet Genomics 2005 0.87
102 Genome-wide association analysis of eating disorder-related symptoms, behaviors, and personality traits. Am J Med Genet B Neuropsychiatr Genet 2012 0.85
103 Promoter polymorphisms and allelic imbalance in ABCB1 expression. Pharmacogenet Genomics 2007 0.85
104 Genome wide association analysis of a founder population identified TAF3 as a gene for MCHC in humans. PLoS One 2013 0.78
105 Erratum: Whole-genome sequence-based analysis of thyroid function. Nat Commun 2015 0.77
106 Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis. Am J Hum Genet 2016 0.76
107 Association of genetic loci: replication or not, that is the question. Neurology 2005 0.76
108 Corrigendum: Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming. Nat Commun 2017 0.75
109 Erratum: A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans. Nat Commun 2015 0.75