Published in J Neurophysiol on January 27, 2011
The transient receptor potential channel TRPA1: from gene to pathophysiology. Pflugers Arch (2012) 1.63
TRESK channel contribution to nociceptive sensory neurons excitability: modulation by nerve injury. Mol Pain (2011) 1.09
Facial injections of pruritogens or algogens elicit distinct behavior responses in rats and excite overlapping populations of primary sensory and trigeminal subnucleus caudalis neurons. J Neurophysiol (2011) 1.01
Perceptual mapping of chemesthetic stimuli in naïve assessors. Chemosens Percept (2015) 0.84
Anti-hyperalgesic effects of anti-serotonergic compounds on serotonin- and capsaicin-evoked thermal hyperalgesia in the rat. Neuroscience (2011) 0.83
Modulation of TRESK background K+ channel by membrane stretch. PLoS One (2013) 0.82
Novel menthol-derived cooling compounds activate primary and second-order trigeminal sensory neurons and modulate lingual thermosensitivity. Chem Senses (2011) 0.81
Behavioral model of itch, alloknesis, pain and allodynia in the lower hindlimb and correlative responses of lumbar dorsal horn neurons in the mouse. Neuroscience (2014) 0.80
Eugenol and carvacrol induce temporally desensitizing patterns of oral irritation and enhance innocuous warmth and noxious heat sensation on the tongue. Pain (2013) 0.78
Eugenol and carvacrol excite first- and second-order trigeminal neurons and enhance their heat-evoked responses. Neuroscience (2014) 0.78
Gustatory modulation of the responses of trigeminal subnucleus caudalis neurons to noxious stimulation of the tongue in rats. Eur J Neurosci (2013) 0.77
Food vibrations: Asian spice sets lips trembling. Proc Biol Sci (2013) 0.76
Thermosensitive transient receptor potential (TRP) channel agonists and their role in mechanical, thermal and nociceptive sensations as assessed using animal models. Chemosens Percept (2015) 0.75
Sanshool on The Fingertip Interferes with Vibration Detection in a Rapidly-Adapting (RA) Tactile Channel. PLoS One (2016) 0.75
The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature (1997) 30.59
A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain (1988) 18.17
Impaired nociception and pain sensation in mice lacking the capsaicin receptor. Science (2000) 15.16
The cloned capsaicin receptor integrates multiple pain-producing stimuli. Neuron (1998) 13.03
ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures. Cell (2003) 10.94
A TRP channel that senses cold stimuli and menthol. Cell (2002) 8.66
Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin. Neuron (2004) 8.17
The menthol receptor TRPM8 is the principal detector of environmental cold. Nature (2007) 6.16
Attenuated cold sensitivity in TRPM8 null mice. Neuron (2007) 4.73
TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells. Nature (2004) 4.50
Nociceptor and hair cell transducer properties of TRPA1, a channel for pain and hearing. J Neurosci (2005) 3.99
Specificity of cold thermotransduction is determined by differential ionic channel expression. Nat Neurosci (2002) 3.01
Capsaicin binds to the intracellular domain of the capsaicin-activated ion channel. J Neurosci (1999) 2.29
TRPA1 modulates mechanotransduction in cutaneous sensory neurons. J Neurosci (2009) 2.07
Characterization of the mouse cold-menthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a fluorometric imaging plate reader (FLIPR) assay. Br J Pharmacol (2004) 1.97
Emergence of functional sensory subtypes as defined by transient receptor potential channel expression. J Neurosci (2007) 1.87
Pungent agents from Szechuan peppers excite sensory neurons by inhibiting two-pore potassium channels. Nat Neurosci (2008) 1.66
Paraesthesiae from ectopic impulse generation in human sensory nerves. Brain (1980) 1.61
Variable threshold of trigeminal cold-thermosensitive neurons is determined by a balance between TRPM8 and Kv1 potassium channels. J Neurosci (2009) 1.61
Enhanced withdrawal responses to heat and mechanical stimuli following intraplantar injection of capsaicin in rats. Pain (1996) 1.49
Radial stretch reveals distinct populations of mechanosensitive mammalian somatosensory neurons. Proc Natl Acad Sci U S A (2008) 1.24
Low-threshold mechanoreceptive afferents in the human lingual nerve. J Neurophysiol (1997) 1.23
Hydroxy-alpha-sanshool activates TRPV1 and TRPA1 in sensory neurons. Eur J Neurosci (2007) 1.16
Alkylamides that produce tingling paresthesia activate tactile and thermal trigeminal neurons. Brain Res (1999) 1.11
Compounds from Sichuan and Melegueta peppers activate, covalently and non-covalently, TRPA1 and TRPV1 channels. Br J Pharmacol (2009) 1.09
Topical application of L-menthol induces heat analgesia, mechanical allodynia, and a biphasic effect on cold sensitivity in rats. Behav Brain Res (2010) 1.08
Converting cold into pain. Exp Brain Res (2009) 1.06
Pungent qualities of sanshool-related compounds evaluated by a sensory test and activation of rat TRPV1. Biosci Biotechnol Biochem (2005) 1.04
Physiological basis of tingling paresthesia evoked by hydroxy-alpha-sanshool. J Neurosci (2010) 0.98
Behavioral evidence of thermal hyperalgesia and mechanical allodynia induced by intradermal cinnamaldehyde in rats. Neurosci Lett (2010) 0.95
Self- and cross-desensitization of oral irritation by menthol and cinnamaldehyde (CA) via peripheral interactions at trigeminal sensory neurons. Chem Senses (2010) 0.92
Attenuation of formalin-induced nociceptive behaviors following local peripheral injection of gabapentin. Pain (1998) 0.92
Psychophysical evaluation of a sanshool derivative (alkylamide) and the elucidation of mechanisms subserving tingle. PLoS One (2010) 0.91
Tongue mechanoreceptors: comparison of afferent fibers in the lingual nerve and chorda tympani. Brain Res (1971) 0.85
Activation of lumbar spinal wide-dynamic range neurons by a sanshool derivative. J Neurophysiol (2009) 0.84
Synthesis and evaluation of new alkylamides derived from alpha-hydroxysanshool, the pungent molecule in szechuan pepper. J Agric Food Chem (2009) 0.81
The molecular basis of individual differences in phenylthiocarbamide and propylthiouracil bitterness perception. Curr Biol (2005) 3.41
Bitter taste receptors for saccharin and acesulfame K. J Neurosci (2004) 2.09
Effects of TRPA1 agonists mustard oil and cinnamaldehyde on lumbar spinal wide-dynamic range neuronal responses to innocuous and noxious cutaneous stimuli in rats. J Neurophysiol (2007) 1.71
Isoflurane anesthesia blunts cerebral responses to noxious and innocuous stimuli: a fMRI study. Life Sci (1997) 1.57
Activation of superficial dorsal horn neurons in the mouse by a PAR-2 agonist and 5-HT: potential role in itch. J Neurosci (2009) 1.48
Allelic polymorphism within the TAS1R3 promoter is associated with human taste sensitivity to sucrose. Curr Biol (2009) 1.39
Excitation of mouse superficial dorsal horn neurons by histamine and/or PAR-2 agonist: potential role in itch. J Neurophysiol (2009) 1.38
Quantifying spatial heterogeneity in dynamic contrast-enhanced MRI parameter maps. Magn Reson Med (2009) 1.37
Responses of superficial dorsal horn neurons to intradermal serotonin and other irritants: comparison with scratching behavior. J Neurophysiol (2002) 1.36
Enhanced scratching evoked by PAR-2 agonist and 5-HT but not histamine in a mouse model of chronic dry skin itch. Pain (2010) 1.34
Dorsal horn neurons expressing NK-1 receptors mediate scratching in rats. Neuroreport (2010) 1.34
Neural processing of itch. Neuroscience (2013) 1.32
Scratching behavior and Fos expression in superficial dorsal horn elicited by protease-activated receptor agonists and other itch mediators in mice. J Pharmacol Exp Ther (2009) 1.31
Determination of serum propofol concentrations by breath analysis using ion mobility spectrometry. Br J Anaesth (2009) 1.20
In vitro culture studies of Sutherlandia frutescens on human tumor cell lines. J Ethnopharmacol (2004) 1.19
The binding site for neohesperidin dihydrochalcone at the human sweet taste receptor. BMC Struct Biol (2007) 1.17
Oral irritant properties of menthol: sensitizing and desensitizing effects of repeated application and cross-desensitization to nicotine. Physiol Behav (2001) 1.16
Facial injections of pruritogens and algogens excite partly overlapping populations of primary and second-order trigeminal neurons in mice. J Neurophysiol (2010) 1.15
Superficial dorsal horn neurons identified by intracutaneous histamine: chemonociceptive responses and modulation by morphine. J Neurophysiol (2000) 1.15
Neurons in superficial trigeminal subnucleus caudalis responsive to oral cooling, menthol, and other irritant stimuli. J Neurophysiol (2006) 1.13
Differential itch- and pain-related behavioral responses and µ-opoid modulation in mice. Acta Derm Venereol (2010) 1.12
Oral irritation by mustard oil: self-desensitization and cross-desensitization with capsaicin. Chem Senses (2003) 1.10
Naturally occurring hypothermia is more advantageous than fever in severe forms of lipopolysaccharide- and Escherichia coli-induced systemic inflammation. Am J Physiol Regul Integr Comp Physiol (2012) 1.10
Modulation of bitter taste perception by a small molecule hTAS2R antagonist. Curr Biol (2010) 1.09
Role of TNF-alpha in sensitization of nociceptive dorsal horn neurons induced by application of nucleus pulposus to L5 dorsal root ganglion in rats. Pain (2004) 1.09
Opioid modulation of scratching and spinal c-fos expression evoked by intradermal serotonin. J Neurosci (2003) 1.08
Prenatal diagnosis of solid placental masses: the value of color flow imaging. Ultrasound Obstet Gynecol (2000) 1.08
Topical application of L-menthol induces heat analgesia, mechanical allodynia, and a biphasic effect on cold sensitivity in rats. Behav Brain Res (2010) 1.08
Association between common variation in genes encoding sweet taste signaling components and human sucrose perception. Chem Senses (2010) 1.06
Modulation of oral heat and cold pain by irritant chemicals. Chem Senses (2007) 1.06
Antinociception induced by chronic exposure of rats to cigarette smoke. Neurosci Lett (2004) 1.06
Mouse model of touch-evoked itch (alloknesis). J Invest Dermatol (2012) 1.04
Fetal prognosis in varix of the intrafetal umbilical vein. J Ultrasound Med (1998) 1.04
5-Hydroxytryptamine (5-HT)2 receptor involvement in acute 5-HT-evoked scratching but not in allergic pruritus induced by dinitrofluorobenzene in rats. J Pharmacol Exp Ther (2003) 1.04
Deletion of the preprotachykinin A gene in mice does not reduce scratching behavior elicited by intradermal serotonin. Neurosci Lett (2003) 1.02
Nicotinic receptor involvement in antinociception induced by exposure to cigarette smoke. Neurosci Lett (2005) 1.01
Spinal c-fos expression associated with spontaneous biting in a mouse model of dry skin pruritus. Neurosci Lett (2004) 1.01
Facial injections of pruritogens or algogens elicit distinct behavior responses in rats and excite overlapping populations of primary sensory and trigeminal subnucleus caudalis neurons. J Neurophysiol (2011) 1.01
Behavioral and electrophysiological assessment of hyperalgesia and changes in dorsal horn responses following partial sciatic nerve ligation in rats. Pain (1996) 0.99
Sensitization, desensitization and stimulus-induced recovery of trigeminal neuronal responses to oral capsaicin and nicotine. J Neurophysiol (2000) 0.99
Spontaneous itch in the absence of hyperalgesia in a mouse hindpaw dry skin model. Neurosci Lett (2010) 0.98
Neurobiological and psychophysical mechanisms underlying the oral sensation produced by carbonated water. J Neurosci (1999) 0.97
Nicotine suppression of gustatory responses of neurons in the nucleus of the solitary tract. J Neurophysiol (2006) 0.96
Halothane and propofol differentially affect electroencephalographic responses to noxious stimulation. Br J Anaesth (2005) 0.96
Propofol directly depresses lumbar dorsal horn neuronal responses to noxious stimulation in goats. Can J Anaesth (2000) 0.95
Behavioral evidence of thermal hyperalgesia and mechanical allodynia induced by intradermal cinnamaldehyde in rats. Neurosci Lett (2010) 0.95
Quantitative and qualitative effects of isoflurane on movement occurring after noxious stimulation. Anesthesiology (1999) 0.95
Anti-proliferative and antioxidant activities of Saposhnikovia divaricata. Oncol Rep (2007) 0.95
In vivo characterization of clinical anaesthesia and its components. Br J Anaesth (2002) 0.95
Roles for substance P and gastrin-releasing peptide as neurotransmitters released by primary afferent pruriceptors. J Neurophysiol (2012) 0.95
Taste suppression following lingual capsaicin pre-treatment in humans. Chem Senses (2002) 0.95
The organum vasculosum laminae terminalis in immune-to-brain febrigenic signaling: a reappraisal of lesion experiments. Am J Physiol Regul Integr Comp Physiol (2003) 0.94
Confirmation of the location of spinothalamic neurons in the cat and monkey by the retrograde transport of horseradish peroxidase. Brain Res (1975) 0.94
Enhanced responses of lumbar superficial dorsal horn neurons to intradermal PAR-2 agonist but not histamine in a mouse hindpaw dry skin itch model. J Neurophysiol (2011) 0.93
Self- and cross-desensitization of oral irritation by menthol and cinnamaldehyde (CA) via peripheral interactions at trigeminal sensory neurons. Chem Senses (2010) 0.92
Dopamine reuptake inhibition in the rostral agranular insular cortex produces antinociception. J Neurosci (1999) 0.92
Mustard oil has differential effects on the response of trigeminal caudalis neurons to heat and acidity. Pain (2004) 0.92
Stability and cytotoxicity of gambogic acid and its derivative, gambogoic acid. Biol Pharm Bull (2005) 0.92
Psychophysical evaluation of a sanshool derivative (alkylamide) and the elucidation of mechanisms subserving tingle. PLoS One (2010) 0.91
Spatial summation in human thermal pain perception: comparison within and between dermatomes. Pain (1992) 0.91
In vitro anti-proliferative and antioxidant studies on Devil's Club Oplopanax horridus. J Ethnopharmacol (2006) 0.91
Cross-desensitization of responses of rat trigeminal subnucleus caudalis neurons to cinnamaldehyde and menthol. Neurosci Lett (2007) 0.91
Antiproliferation effect of Rosemary (Rosmarinus officinalis) on human ovarian cancer cells in vitro. Phytomedicine (2012) 0.91
Application of nucleus pulposus to L5 dorsal root ganglion in rats enhances nociceptive dorsal horn neuronal windup. J Neurophysiol (2005) 0.90
Differential effects of halothane and isoflurane on lumbar dorsal horn neuronal windup and excitability. Br J Anaesth (2005) 0.89
Quantitative assessment of directed hind limb scratching behavior as a rodent itch model. J Neurosci Methods (2003) 0.89
c-fos expression in superficial dorsal horn of cervical spinal cord associated with spontaneous scratching in rats with dry skin. Neurosci Lett (2003) 0.89
Spinal NMDA receptor involvement in expansion of dorsal horn neuronal receptive field area produced by intracutaneous histamine. J Neurophysiol (1998) 0.89