Published in Immunotherapy on March 01, 2011
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T-bet regulates IgG class switching and pathogenic autoantibody production. Proc Natl Acad Sci U S A (2002) 2.63
T-bet negatively regulates autoimmune myocarditis by suppressing local production of interleukin 17. J Exp Med (2006) 2.38
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T-bet controls autoaggressive CD8 lymphocyte responses in type 1 diabetes. J Exp Med (2004) 1.88
T-bet-dependent S1P5 expression in NK cells promotes egress from lymph nodes and bone marrow. J Exp Med (2009) 1.86
T-bet deficiency reduces atherosclerosis and alters plaque antigen-specific immune responses. Proc Natl Acad Sci U S A (2005) 1.82
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T-bet upregulation and subsequent interleukin 12 stimulation are essential for induction of Th1 mediated immunopathology in Crohn's disease. Gut (2004) 1.39
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T-bet regulates T-independent IgG2a class switching. Int Immunol (2003) 1.25
T-bet is essential for the progression of experimental autoimmune encephalomyelitis. Immunology (2006) 1.25
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T-bet, a Th1 transcription factor regulates the expression of Tim-3. Eur J Immunol (2010) 1.21
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The activated glucocorticoid receptor inhibits the transcription factor T-bet by direct protein-protein interaction. FASEB J (2007) 1.09
COX-2 inhibitors ameliorate experimental autoimmune encephalomyelitis through modulating IFN-gamma and IL-10 production by inhibiting T-bet expression. J Neuroimmunol (2007) 1.06
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T-bet dependent removal of Sin3A-histone deacetylase complexes at the Ifng locus drives Th1 differentiation. J Immunol (2008) 0.94
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Glucocorticoid treatment reduces T-bet and pSTAT1 expression in mononuclear cells from relapsing remitting multiple sclerosis patients. Clin Immunol (2007) 0.86
T-bet deficiency decreases susceptibility to experimental myasthenia gravis. Exp Neurol (2009) 0.84
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A continuous T-bet expression is required to silence the interleukin-4-producing potential in T helper type 1 cells. Immunology (2009) 0.83
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T-bet, pSTAT1 and pSTAT3 expression in peripheral blood mononuclear cells during pregnancy correlates with post-partum activation of multiple sclerosis. Clin Immunol (2008) 0.77
Tumor necrosis factor alpha production from CD8+ T cells mediates oviduct pathological sequelae following primary genital Chlamydia muridarum infection. Infect Immun (2011) 1.48
Antigen-specific CD4+ T cells produce sufficient IFN-gamma to mediate robust protective immunity against genital Chlamydia muridarum infection. J Immunol (2008) 1.34
Chlamydial protease-like activity factor induces protective immunity against genital chlamydial infection in transgenic mice that express the human HLA-DR4 allele. Infect Immun (2006) 1.27
Mast cells inhibit intramacrophage Francisella tularensis replication via contact and secreted products including IL-4. Proc Natl Acad Sci U S A (2008) 1.21
ERK1-deficient mice show normal T cell effector function and are highly susceptible to experimental autoimmune encephalomyelitis. J Immunol (2005) 1.20
Therapeutic enzyme deimmunization by combinatorial T-cell epitope removal using neutral drift. Proc Natl Acad Sci U S A (2011) 1.18
The cytokine signature of MOG-specific CD4 cells in the EAE of C57BL/6 mice. J Neuroimmunol (2005) 1.01
Allergen-specific MHC class II tetramer+ cells are detectable in allergic, but not in nonallergic, individuals. J Immunol (2006) 0.97
Regulation of adaptive immunity by the fractalkine receptor during autoimmune inflammation. J Immunol (2013) 0.95
Myelin-reactive type B T cells and T cells specific for low-affinity MHC-binding myelin peptides escape tolerance in HLA-DR transgenic mice. J Immunol (2008) 0.92
The PLPp-specific T-cell population promoted by pertussis toxin is characterized by high frequencies of IL-17-producing cells. Cytokine (2007) 0.89
Immunization with a combination of integral chlamydial antigens and a defined secreted protein induces robust immunity against genital chlamydial challenge. Infect Immun (2010) 0.88
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Immunoenrichment microwave and magnetic proteomics for quantifying CD47 in the experimental autoimmune encephalomyelitis model of multiple sclerosis. Electrophoresis (2012) 0.83
Mast cell TLR2 signaling is crucial for effective killing of Francisella tularensis. J Immunol (2012) 0.82
Non-FcεR bearing mast cells secrete sufficient interleukin-4 to control Francisella tularensis replication within macrophages. Cytokine (2011) 0.82
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Microwave and magnetic (M(2) ) proteomics of the experimental autoimmune encephalomyelitis animal model of multiple sclerosis. Electrophoresis (2012) 0.81
The critical role of antigen-presentation-induced cytokine crosstalk in the central nervous system in multiple sclerosis and experimental autoimmune encephalomyelitis. J Interferon Cytokine Res (2011) 0.80
The contribution of interleukin-12/interferon-gamma axis in protection against neonatal pulmonary Chlamydia muridarum challenge. J Interferon Cytokine Res (2010) 0.80
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Mast cells: multitalented facilitators of protection against bacterial pathogens. Expert Rev Clin Immunol (2013) 0.78
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Anaphylaxis and mortality induced by treatment of mice with anti-VLA-4 antibody and pertussis toxin. J Immunol (2011) 0.78
A T cell epitope-based vaccine protects against chlamydial infection in HLA-DR4 transgenic mice. Vaccine (2013) 0.78
Small molecule inhibitor of antigen binding and presentation by HLA-DR2b as a therapeutic strategy for the treatment of multiple sclerosis. J Immunol (2013) 0.77
Induction of polyclonal CD8+ T cell activation and effector function by Pertussis toxin. Cell Immunol (2010) 0.77
Prosurvival and proapoptotic functions of ERK1/2 activation in murine thymocytes in vitro. Cell Immunol (2009) 0.76
CD19 as a molecular target in CNS autoimmunity. Acta Neuropathol (2014) 0.76
Immunological adjuvants efficiently induce antigen-specific T cell responses in old mice: implications for vaccine adjuvant development in aged individuals. Cell Immunol (2002) 0.76
Stability of T-cell lineages in autoimmune diseases. Expert Rev Clin Immunol (2012) 0.75
Is there a place for 'immuno' in the immunotherapy of multiple sclerosis? Immunotherapy (2009) 0.75
Anti-CRLF2 Antibody-Armored Biodegradable Nanoparticles for Childhood B-ALL. Part Part Syst Charact (2013) 0.75
Suramin has adjuvant properties and promotes expansion of antigen-specific Th1 and Th2 cells in vivo. Int Immunopharmacol (2004) 0.75