Published in Proc Natl Acad Sci U S A on April 16, 2002
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Basophils and the T helper 2 environment can promote the development of lupus nephritis. Nat Med (2010) 3.24
T-bet is essential for encephalitogenicity of both Th1 and Th17 cells. J Exp Med (2009) 2.96
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T-bet deficiency reduces atherosclerosis and alters plaque antigen-specific immune responses. Proc Natl Acad Sci U S A (2005) 1.82
Contribution of IRF5 in B cells to the development of murine SLE-like disease through its transcriptional control of the IgG2a locus. Proc Natl Acad Sci U S A (2010) 1.79
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T-bet, a Th1 transcription factor, is up-regulated in T cells from patients with aplastic anemia. Blood (2006) 1.64
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T-bet is required for protection against vaccinia virus infection. J Virol (2005) 1.00
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T-bet and mucosal Th1 responses in the gastrointestinal tract. Gut (2002) 0.88
Altered type II interferon precedes autoantibody accrual and elevated type I interferon activity prior to systemic lupus erythematosus classification. Ann Rheum Dis (2016) 0.87
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Lymphadenopathy in a novel mouse model of Bartonella-induced cat scratch disease results from lymphocyte immigration and proliferation and is regulated by interferon-alpha/beta. Am J Pathol (2008) 0.87
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Dysregulation of innate and adaptive serum mediators precedes systemic lupus erythematosus classification and improves prognostic accuracy of autoantibodies. J Autoimmun (2016) 0.84
Hepatitis C viremia reversibly maintains subset of antigen-specific T-bet+ tissue-like memory B-cells. J Viral Hepat (2016) 0.84
T-bet regulates immunity to Francisella tularensis live vaccine strain infection, particularly in lungs. Infect Immun (2014) 0.83
Delineation of the role of platelet-activating factor in the immunoglobulin G2 antibody response. Clin Diagn Lab Immunol (2004) 0.83
B cells expressing the transcription factor T-bet drive lupus-like autoimmunity. J Clin Invest (2017) 0.83
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Host differences in influenza-specific CD4 T cell and B cell responses are modulated by viral strain and route of immunization. PLoS One (2012) 0.82
T-bet+ B cells are induced by human viral infections and dominate the HIV gp140 response. JCI Insight (2017) 0.82
Cutting Edge: IL-4, IL-21, and IFN-γ Interact To Govern T-bet and CD11c Expression in TLR-Activated B Cells. J Immunol (2016) 0.81
Linking obesity with type 2 diabetes: the role of T-bet. Diabetes Metab Syndr Obes (2014) 0.81
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Protective neutralizing influenza antibody response in the absence of T follicular helper cells. Nat Immunol (2016) 0.79
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An Excess of the Proinflammatory Cytokines IFN-γ and IL-12 Impairs the Development of the Memory CD8+ T Cell Response to Chlamydia trachomatis. J Immunol (2015) 0.76
Tbet or Continued RORγt Expression Is Not Required for Th17-Associated Immunopathology. J Immunol (2016) 0.76
T Cell Production of IFNγ in Response to TLR7/IL-12 Stimulates Optimal B Cell Responses to Viruses. PLoS One (2016) 0.75
T-bet Is Required for the Rapid Clearance of Attenuated Rabies Virus from Central Nervous System Tissue. J Immunol (2015) 0.75
Crystal structure of the DNA binding domain of the transcription factor T-bet suggests simultaneous recognition of distant genome sites. Proc Natl Acad Sci U S A (2016) 0.75
Tbet Deficiency Causes T Helper Cell Dependent Airways Eosinophilia and Mucus Hypersecretion in Response to Rhinovirus Infection. PLoS Pathog (2016) 0.75
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The influence of tobacco smoking on humoral immune response in insulin dependent diabetic pregnancy. Indian J Clin Biochem (2006) 0.75
Sterilizing immunity to influenza virus infection requires local antigen-specific T cell response in the lungs. Sci Rep (2016) 0.75
STAT1 regulates marginal zone B cell differentiation in response to inflammation and infection with blood-borne bacteria. J Exp Med (2016) 0.75
Dissecting the relationships of IgG subclasses and complements in membranous lupus nephritis and idiopathic membranous nephropathy. PLoS One (2017) 0.75
Boosting Adaptive Immunity: A New Role for PAFR Antagonists. Sci Rep (2016) 0.75
T-bet(+)CD11c(+) B cells are critical for antichromatin immunoglobulin G production in the development of lupus. Arthritis Res Ther (2017) 0.75
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The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cells. Nat Immunol (2009) 1.66
IL-2 production in developing Th1 cells is regulated by heterodimerization of RelA and T-bet and requires T-bet serine residue 508. J Exp Med (2005) 1.64
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T-bet, a T cell-associated transcription factor, is expressed in Hodgkin's lymphoma. Hum Pathol (2005) 1.52
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Administration of BMP2/7 in utero partially reverses Rubinstein-Taybi syndrome-like skeletal defects induced by Pdk1 or Cbp mutations in mice. J Clin Invest (2011) 1.50
Transcription factor T-bet regulates inflammatory arthritis through its function in dendritic cells. J Clin Invest (2006) 1.49
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Increased susceptibility of mice lacking T-bet to infection with Mycobacterium tuberculosis correlates with increased IL-10 and decreased IFN-gamma production. J Immunol (2005) 1.41
Transcription factor T-bet regulates skin sclerosis through its function in innate immunity and via IL-13. Proc Natl Acad Sci U S A (2007) 1.39
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Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy. Hum Mol Genet (2012) 1.36
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T-bet plays a key role in NK-mediated control of melanoma metastatic disease. J Immunol (2008) 1.32
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