Published in Cell on July 13, 1990
Suppression of chromosome segregation defects of Escherichia coli muk mutants by mutations in topoisomerase I. Proc Natl Acad Sci U S A (2000) 2.32
Closing the ring: links between SMC proteins and chromosome partitioning, condensation, and supercoiling. Proc Natl Acad Sci U S A (2000) 2.14
Optimization of plasmid maintenance in the attenuated live vector vaccine strain Salmonella typhi CVD 908-htrA. Infect Immun (1999) 1.66
Definition of a minimal plasmid stabilization system from the broad-host-range plasmid RK2. J Bacteriol (1992) 1.48
Yeast telomere repeat sequence (TRS) improves circular plasmid segregation, and TRS plasmid segregation involves the RAP1 gene product. Mol Cell Biol (1992) 1.29
Minimal replication origin of the 200-kilobase Halobacterium plasmid pNRC100. J Bacteriol (1993) 1.26
Gyrase-dependent stabilization of pSC101 plasmid inheritance by transcriptionally active promoters. EMBO J (1991) 1.11
Excess intracellular concentration of the pSC101 RepA protein interferes with both plasmid DNA replication and partitioning. J Bacteriol (1993) 1.04
A single 43-bp sopC repeat of plasmid mini-F is sufficient to allow assembly of a functional nucleoprotein partition complex. Proc Natl Acad Sci U S A (1994) 1.00
Random diffusion can account for topA-dependent suppression of partition defects in low-copy-number plasmids. J Bacteriol (1992) 1.00
The pSC101 par locus alters protein-DNA interactions in vivo at the plasmid replication origin. J Bacteriol (1993) 0.94
Effects of the pSC101 partition (par) locus on in vivo DNA supercoiling near the plasmid replication origin. Nucleic Acids Res (1995) 0.88
Two enhancer elements for DNA replication of pSC101, par and a palindromic binding sequence of the Rep protein. J Bacteriol (1995) 0.88
Boundaries of the pSC101 minimal replicon are conditional. J Bacteriol (1995) 0.86
Isolation and characterization of plasmid mutations that enable partitioning of pSC101 replicons lacking the partition (par) locus. J Bacteriol (1995) 0.86
Separate roles of Escherichia coli replication proteins in synthesis and partitioning of pSC101 plasmid DNA. J Bacteriol (1999) 0.86
A DNA segment conferring stable maintenance on R6K gamma-origin core replicons. J Bacteriol (1995) 0.82
Opening the Strands of Replication Origins-Still an Open Question. Front Mol Biosci (2016) 0.78
The Escherichia coli terB sequence affects maintenance of a plasmid with the M13 phage replication origin. J Bacteriol (1991) 0.77
Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmid. J Bacteriol (1978) 75.38
Nonchromosomal antibiotic resistance in bacteria: genetic transformation of Escherichia coli by R-factor DNA. Proc Natl Acad Sci U S A (1972) 57.06
Analysis of gene control signals by DNA fusion and cloning in Escherichia coli. J Mol Biol (1980) 41.18
Construction of biologically functional bacterial plasmids in vitro. Proc Natl Acad Sci U S A (1973) 25.61
Lactose genes fused to exogenous promoters in one step using a Mu-lac bacteriophage: in vivo probe for transcriptional control sequences. Proc Natl Acad Sci U S A (1979) 22.59
High frequency transformation of Bacillus subtilis protoplasts by plasmid DNA. Mol Gen Genet (1979) 17.16
Transformation of Salmonella typhimurium by plasmid deoxyribonucleic acid. J Bacteriol (1974) 15.89
Recircularization and autonomous replication of a sheared R-factor DNA segment in Escherichia coli transformants. Proc Natl Acad Sci U S A (1973) 13.45
Uniform nomenclature for bacterial plasmids: a proposal. Bacteriol Rev (1976) 12.28
Non-chromosomal antibiotic resistance in bacteria. II. Molecular nature of R-factors isolated from Proteus mirabilis and Escherichia coli. J Mol Biol (1970) 11.86
Electron microscope heteroduplex studies of sequence relations among plasmids of Escherichia coli. II. Structure of drug resistance (R) factors and F factors. J Mol Biol (1973) 11.40
Replication and transcription of eukaryotic DNA in Escherichia coli. Proc Natl Acad Sci U S A (1974) 10.51
Multiple molecular species of circular R-factor DNA isolated from Escherichia coli. Nature (1969) 9.02
Cloning, isolation, and characterization of replication regions of complex plasmid genomes. Proc Natl Acad Sci U S A (1975) 8.85
Phenotypic expression in E. coli of a DNA sequence coding for mouse dihydrofolate reductase. Nature (1978) 8.76
Site specific recA--independent recombination between bacterial plasmids: involvement of palindromes at the recombinational loci. Proc Natl Acad Sci U S A (1975) 7.60
Decay of mRNA in Escherichia coli: investigation of the fate of specific segments of transcripts. Proc Natl Acad Sci U S A (1983) 6.79
Nucleotide sequence of cloned cDNA for bovine corticotropin-beta-lipotropin precursor. Nature (1979) 6.56
Identification and characterization of recD, a gene affecting plasmid maintenance and recombination in Escherichia coli. J Bacteriol (1986) 6.06
Gene expression in Streptomyces: construction and application of promoter-probe plasmid vectors in Streptomyces lividans. Mol Gen Genet (1982) 5.99
Replication control in a composite plasmid constructed by in vitro linkage of two distinct replicons. Nature (1976) 5.73
Transposable genetic elements and plasmid evolution. Nature (1976) 5.58
Revised interpretation of the origin of the pSC101 plasmid. J Bacteriol (1977) 5.51
Genome construction between bacterial species in vitro: replication and expression of Staphylococcus plasmid genes in Escherichia coli. Proc Natl Acad Sci U S A (1974) 5.47
Occurrence of insertion sequence (IS) regions on plasmid deoxyribonucleic acid as direct and inverted nucleotide sequence duplications. J Bacteriol (1975) 5.35
CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma. Proc Natl Acad Sci U S A (1996) 5.26
Nonchromosomal antibiotic resistance in bacteria. V. Isolation and characterization of R factor mutants exhibiting temperature-sensitive repression of fertility. J Bacteriol (1972) 4.85
Molecular and genetic studies of an R factor system consisting of independent transfer and drug resistance plasmids. J Bacteriol (1973) 4.81
Are chlamydial infections the most prevalent venereal disease? JAMA (1975) 4.79
Alignment of genetic and restriction maps of the photosynthesis region of the Rhodopseudomonas capsulata chromosome by a conjugation-mediated marker rescue technique. J Bacteriol (1983) 4.56
Dengue and chikungunya virus infection in man in Thailand, 1962-1964. I. Observations on hospitalized patients with hemorrhagic fever. Am J Trop Med Hyg (1969) 4.41
Cloning and characterization of EcoRI and HindIII restriction endonuclease-generated fragments of antibiotic resistance plasmids R6-5 and R6. Mol Gen Genet (1978) 4.33
Observations related to pathogenesis of dengue hemorrhagic fever. IV. Relation of disease severity to antibody response and virus recovered. Yale J Biol Med (1970) 4.30
Utilization of two distinct modes of replication by a hybrid plasmid constructed in vitro from separate replicons. Proc Natl Acad Sci U S A (1974) 4.27
Structure and genomic organization of the mouse dihydrofolate reductase gene. Cell (1980) 4.25
3'-end labeling of DNA with [alpha-32P]cordycepin-5'-triphosphate. Gene (1980) 4.22
Differential expression of photosynthesis genes in R. capsulata results from segmental differences in stability within the polycistronic rxcA transcript. Cell (1985) 4.15
Selected translocation of plasmid genes: frequency and regional specificity of translocation of the Tn3 element. J Bacteriol (1977) 4.08
Partitioning of bacterial plasmids during cell division: a cis-acting locus that accomplishes stable plasmid inheritance. Cell (1980) 4.01
Isolation of catenated forms of R factor DNA from minicells. Nat New Biol (1971) 3.99
Indirect selection of bacterial plasmids lacking identifiable phenotypic properties. J Bacteriol (1975) 3.88
Cloning and analysis of strong promoters is made possible by the downstream placement of a RNA termination signal. Proc Natl Acad Sci U S A (1981) 3.77
Isolation of histone genes from unfractionated sea urchin DNA by subculture cloning in E. coli. Nature (1975) 3.70
Involvement of multiple translocating DNA segments and recombinational hotspots in the structural evolution of bacterial plasmids. J Mol Biol (1976) 3.63
Cloning and endonuclease mapping of the hepatitis B viral genome. Nature (1979) 3.62
Letter: Potential biohazards of recombinant DNA molecules. Science (1974) 3.45
Penicillinase-producing Neisseria gonorrhoeae. Lancet (1976) 3.37
A sensitive radioimmunoassay for detecting products translated from cloned DNA fragments. Cell (1978) 3.30
Hemorrhagic fevers of Southeast Asia and South America: a comparative appraisal. Prog Med Virol (1967) 3.22
Growth-rate dependent regulation of mRNA stability in Escherichia coli. Nature (1984) 3.06
Tsg101: a novel tumor susceptibility gene isolated by controlled homozygous functional knockout of allelic loci in mammalian cells. Cell (1996) 2.92
Studies of mouse mitochondrial DNA in Escherichia coli: structure and function of the eucaryotic-procaryotic chimeric plasmids. Cell (1975) 2.80
The stability of E. coli gene transcripts is dependent on determinants localized to specific mRNA segments. Cell (1986) 2.79
Non-chromosomal antibiotic resistance in bacteria. 3. Isolation of the discrete transfer unit of the R-factor R1. Proc Natl Acad Sci U S A (1970) 2.76
In vivo site-specific genetic recombination promoted by the EcoRI restriction endonuclease. Proc Natl Acad Sci U S A (1977) 2.74
Nucleotide sequences encoding and promoting expression of three antibiotic resistance genes indigenous to Streptomyces. Mol Gen Genet (1985) 2.71
Coryneform bacterial endocarditis: difficulties in diagnosis and treatment, presentation of three cases, and review of literature. Mayo Clin Proc (1977) 2.63
The usefulness of preoperative laboratory screening. JAMA (1985) 2.55
An intercistronic stem-loop structure functions as an mRNA decay terminator necessary but insufficient for puf mRNA stability. Cell (1988) 2.53
Global analysis of growth phase responsive gene expression and regulation of antibiotic biosynthetic pathways in Streptomyces coelicolor using DNA microarrays. Genes Dev (2001) 2.49
Shock associated with dengue infection. I. Clinical and physiologic manifestations of dengue hemorrhagic fever in Thailand, 1964. J Pediatr (1966) 2.45
A+U content rather than a particular nucleotide order determines the specificity of RNase E cleavage. J Biol Chem (1994) 2.39
Identification and characterization of a self-regulated repressor of translocation of the Tn3 element. Proc Natl Acad Sci U S A (1979) 2.37
New chemical methods for synthesizing polynucleotides. Nucleic Acids Symp Ser (1980) 2.32
Translocation specificity of the Tn3 element: characterization of sites of multiple insertions. Cell (1980) 2.31
Structural and functional analysis of cloned DNA segments containing the replication and incompatibility regions of a miniplasmid derived from a copy number mutant of NR1. J Bacteriol (1979) 2.29
Complete nucleotide sequence of the Streptomyces lividans plasmid pIJ101 and correlation of the sequence with genetic properties. J Bacteriol (1988) 2.29
The rate of processing and degradation of antisense RNAI regulates the replication of ColE1-type plasmids in vivo. Cell (1991) 2.27
RNA degradation in Escherichia coli regulated by 3' adenylation and 5' phosphorylation. Nature (1995) 2.26
Carotid endarterectomy--an evidence-based review: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology (2005) 2.26
Transposition protein of Tn3: identification and characterisation of an essential repressor-controlled gene product. Nature (1980) 2.24
Effect of premature termination of translation on mRNA stability depends on the site of ribosome release. Proc Natl Acad Sci U S A (1987) 2.24
Prior antiplatelet use does not affect hemorrhage growth or outcome after ICH. Neurology (2009) 2.23
Bovine papilloma virus plasmids replicate randomly in mouse fibroblasts throughout S phase of the cell cycle. Cell (1987) 2.22
Deoxyoligonucleotide synthesis via the phosphoramidite method. Gene Amplif Anal (1983) 2.15
Genetic recombination through protoplast fusion in Streptomyces. Nature (1977) 2.14
Characterization of the structural gene and putative 5'-regulatory sequences for human proopiomelanocortin. Nature (1982) 2.04
The TSG101 tumor susceptibility gene is located in chromosome 11 band p15 and is mutated in human breast cancer. Cell (1997) 2.02
The Escherichia coli pcnB gene promotes adenylylation of antisense RNAI of ColE1-type plasmids in vivo and degradation of RNAI decay intermediates. Proc Natl Acad Sci U S A (1993) 1.99
Structural and functional analysis of the par region of the pSC 10 1 plasmid. Cell (1984) 1.98
A DNA cloning system for interspecies gene transfer in antibiotic-producing Streptomyces. Nature (1980) 1.95
Structural and functional analysis of transcriptional control of the Rhodobacter capsulatus puf operon. J Bacteriol (1989) 1.92
The N-terminal domain of the rne gene product has RNase E activity and is non-overlapping with the arginine-rich RNA-binding site. J Mol Biol (1996) 1.92
Replication timing of DNA sequences associated with human centromeres and telomeres. Mol Cell Biol (1990) 1.89
A TSG101/MDM2 regulatory loop modulates MDM2 degradation and MDM2/p53 feedback control. Proc Natl Acad Sci U S A (2001) 1.88
Excision of chromosomal DNA sequences from Streptomyces coelicolor forms a novel family of plasmids detectable in Streptomyces lividans. Mol Gen Genet (1981) 1.88
Role of DNA in RNA synthesis. XI. Selective transcription of gamma DNA segments in vitro by RNA polymerase of Escherichia coli. J Mol Biol (1967) 1.87
A simple method for quantitative urine culture. N Engl J Med (1967) 1.85
Transcription of complementary strands of phage lambda-DNA in vivo and in vitro. Proc Natl Acad Sci U S A (1967) 1.80
Site-specific RNase E cleavage of oligonucleotides and inhibition by stem-loops. Nature (1995) 1.79
Genetic analysis of the inter-relationship between plasmid replication and incompatibility. Mol Gen Genet (1979) 1.79
Covalently closed circular DNA molecules of low superhelix density as intermediate forms in plasmid replication. Nature (1976) 1.77
Site-specific DNA deletions occurring adjacent to the termini of a transposable ampicillin resistance element (Tn3). J Mol Biol (1977) 1.74
alphabeta sequence of F is IS31. J Bacteriol (1975) 1.73
Cell cycle-dependent subcellular localization of the TSG101 protein and mitotic and nuclear abnormalities associated with TSG101 deficiency. Proc Natl Acad Sci U S A (1998) 1.70
Inhibition of DNA and RNA polymerase reactions by chloroquine. Proc Natl Acad Sci U S A (1965) 1.70
An artificial intelligence program to advise physicians regarding antimicrobial therapy. Comput Biomed Res (1973) 1.69